The Hauptman-Woodward Medical Research Institute attracts talented scientists and support staff to explore exciting research opportunities and the freedom to pursue the unknown. We offer an excellent benefits package including health insurance, generous retirement plan, disability, and life insurance coverage, competitive vacation/holiday policies, and pre-tax spending accounts. The Institute is a welcoming environment and embraces diversity in people as well as the skills they bring to us.

Current Openings:

Postdoctoral Associate

A Postdoctoral Associate position is available based at the Hauptman-Woodward Medical Research Institute (HWI) and affiliated with the University at Buffalo. We are looking for a highly motivated structural biologist with an interest in metalloproteins and methods development to join a project with the Snell and Bowman laboratories involving the structural study of biological systems that are impacted by free radical activity and metalloproteins, where the modeled metal and/or coordination state are of interest for further investigation. The work will involve a collaboration with laboratories at Stanford and Oxford and will use X-ray crystallography, UV-spectroscopy, and micro-PIXE techniques. The eventual aim involves structural studies using X-ray free-electron sources for radiation chemistry-free data. It is possible that neutron studies would also take place. The position involves working directly with the Crystallization Center at the Institute and will have access to a Glacios cryo-EM with Falcon 4 detector. The Institute runs the IMCA beamline at the Advanced Photon Source. It is anticipated that multiple structural techniques will be employed, and while the candidate should have structural biology expertise, they are not expected to be proficient in all structural biology techniques. Molecular biology expertise is required to produce target proteins and complexes. Many techniques will be employed.

This position is based at HWI but offered through the University at Buffalo. Application instructions and details are available at the University of Buffalo job posting site.

Research Scientist

BioXFEL is an NSF Supported Science and Technology Center developing the biological applications of X-ray Free Electron Lasers. It is a consortium of 8 institutions led by staff from the Department of Materials Design and Innovation (MDI) at the University at Buffalo, State University of New York (UB), and administratively headquartered at the Hauptman-Woodward Medical Research Institute. One of the teams in BioXFEL provides data processing support for XFEL experiments around the world. We are looking for a research scientist that can join this team and provide data processing support for crystallographic and potentially solution and single-particle XFEL experiments. The support functions would be based in Buffalo with the opportunity to attend some beamtimes if necessary. The support team consists of staff from multiple BioXFEL institutes. We are looking for a candidate who can operate effectively in a diverse community of students and investigators who shares our vision of helping all constituents reach their full potential.

The successful candidate(s) will be involved with the following:
• Assisting in data processing for crystallographic based XFEL experiments.
• Assisting in the analysis and drafting of publications related to results.
• Establishing expertise to help support potential single-particle and solution-based experiments.
• Helping teach others best practices for data processing.
• Contributing to the scientific development of new techniques and methodologies dependent on level and experience.

The candidate would be based at the Hauptman-Woodward Medical Research Institute in Buffalo New York but work closely with UB, HWI, and BioXFEL scientists and students as part of the effort. This position is based at HWI but offered through the University at Buffalo. Application instructions and details are available at the University of Buffalo job posting site.

EEO Statement

The Hauptman-Woodward Medical Research Institute, Inc. (HWI) as an equal opportunity employer, extends employment opportunities to qualified applicants and employees on a non-discriminatory basis without regard to race, color, sex, creed, age, religion, national origin, marital status, veteran status, sexual orientation, genetic predisposition, carrier status, or disability that would prevent the performance of the essential requirements of the job with or without a reasonable accommodation in compliance with the appropriate New York State and Federal laws, or any other legally protected characteristics. This policy applies to all conditions and terms of employment.