Biology with X-ray Free Electron Lasers (BioXFEL) is a Science and Technology Center established by the National Science Foundation in 2013. Composed of eight U.S. research universities and aimed at addressing the fundamental questions in biology at the molecular level. Using a pulsed hard X-ray laser, our researchers can capture biological molecules in atomic detail, view their functional motions by taking brief snapshots, and observe interactions in their native environment. This opens up a new world to biology, to science, and to human health.

Our Mission

X-ray lasers provide snapshots of unprecedented clarity depicting the building blocks of life. The motions and arrangements of these blocks underlie all biological function.


Lab Groups

The BioXFEL Center benefits from the research performed at several major universities and laboratories. Here you'll find the descriptions of the laboratories affiliated with the Center. 


Our Team

BioXFEL is a consortium of eight national institutions with international collaborations and projects. Our team consists of more than 100 scientists, faculty, staff, students and administrators. Meet some of our member below, or click here to get a full list of our members.


External Advisors

Our expert team of external advisors routinely assesses the progress BioXFEL is making towards our mission and goals and advises the BioXFEL leadership with suggestions for ensuring our success. Meet our advisors below.


Contact Us

For more information

BioXFEL Science and Technology Center
700 Ellicott Street
Buffalo, New York  14203
Phone 716. 898. 8610
Email This email address is being protected from spambots. You need JavaScript enabled to view it.


Join Us

XFEL Biophysics Experimentalist (Arizona State University)  

The Department of Physics at Arizona State University (ASU) seeks applicants for a postdoctoral position in the development of new sample-delivery methods for time-resolved X-ray diffraction of biological samples using X-ray free-electron lasers. The successful applicants will become part of an interdisciplinary team at ASU working on solving important biological questions using XFELs, funded by the NSF's  BioXFEL program, which supports this project at six campuses (see https://www.bioxfel.org ).