News

Structural biology is solved -- now what?

The splendid computational success of AlphaFold and RoseTTAFold in solving the 60-year-old problem of protein folding raises an obvious question: what new avenues should structural biology explore? We propose a strong pivot toward the goal of reading mechanism and function directly from the amino acid sequence.

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Few-fs resolution of a photoactive protein traversing a conical intersection

The structural dynamics of a molecule are determined by the underlying potential energy landscape. Conical intersections are funnels connecting otherwise separate potential energy surfaces. Posited almost a century ago, conical intersections remain the subject of intense scientific interest.

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Filming Antibiotic Resistance in Slow-Motion

Using the X-ray laser European XFEL an international team of researchers has successfully filmed a reaction step that is important for the development of antibiotic resistance.

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BioXFEL Scientific Director John Spence passes away

John Spence, the Scientific Director of BioXFEL, died peacefully Monday morning, June 28, in Boston. John was BioXFEL, he was a visionary in building the team and establishing the resulting community. He strongly impacted all faces of BioXFEL.

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BioXFEL Postdoctoral Fellowship Award

Sabine Botha is a Postdoctoral Research Scholar in the group of Prof. John Spence at Arizona State University. She completed her undergraduate education and masters program at the University of Oxford (UK) in Engineering Science, specializing in Biomedical and Information Engineering.

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Reach Out Semi-finals

We are all very proud of our BioXFEL Scholar, Tek Narsigh Malla and our BioXFEL interns and UPR undergraduates Gabriela Díaz Figueroa and Ana Sofía Santiago-Russe for making it into the Semi-final round of the Reach Out Science Slam Competition. They gave wonderful presentations and  did an excellent job representing the BioXFEL Center.

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