A large international team lead by Valerie Paneels and Gebhard Schertler revealed the molecular mechanism of light receptor activation in the eyes of vertebrae animals by time-resolved serial femtosecond crystallography (TR-SFX). The article appeared in Nature online on March 22 2023. BioXFEL researchers Schmidt and Stojković were invited to write a News and Views article summarizing the general findings focused on the light-activated bovine rhodopsin.

The News and Views article is available here: https://www.nature.com/articles/d41586-023-00504-4.

 

Figure

Caption: The structure of the eye-pigment rhodopsin in the resting state. The retinal is shown in green in the 11-cis configuration. The retinal is bound via a Schiff-base to a lysine sidechain. BioXFEL researchers Schmidt and Stojković wrote a News and Views article in Nature summarizing newest results on the activation of rhodopsin by light.