Positions posted based on availability.

Diamond Light Source

A newly funded Wellcome Investigator Award in Science entitled, “Dynamic Structural Biology: New Tools and Strategies for General Applications” has positions for up to four post-doctoral research associates (PDRAs). The principal science drivers include (metallo)enzymes that either make or degrade antibiotics. These include, but are not limited to, isopenicillin N synthase and a broad range of beta-lactamases.  We conduct research and development at the forefront of serial and time-resolved macromolecular crystallography. We also work to transfer those techniques that are complementary and synergistic between XFELs, synchrotrons and cryo-EM. Our research and development efforts cross several fronts in biophysics from enzyme kinetics to various types of spectroscopy and includes a variety of serial crystallography experiments at Diamond Light Source and at several XFEL facilities around the world. We are seeking scientists interested in time-resolved structural biology and/or with experience in serial femtosecond crystallography or spectroscopy at XFEL sources.

For more information please contact Allen Orville at This email address is being protected from spambots. You need JavaScript enabled to view it. . For details and how to apply please follow these links:

Biophysics (Job ID 10149) with an emphasis on enzymes reaction mechanisms.

Computational (Job ID 10187) with an emphasis on serial crystallography data processing and/or molecular dynamics simulations.

Instrumentation / engineering (Job ID 10188) with an emphasis on serial crystallography correlated with X-ray emission spectroscopy collected at storage rings and/or at XFELs.

Multiple Job Openings at Uppsala University

We are a constellation of young scientists at Uppsala University interested in bioimaging with X-ray lasers.

We have been part several seminal experiments which created the field and are now looking to fill several open positions to create the team that can take the next step!

Link to Job Posting


Multiple Job Openings at Universität Hamburg: “Cluster of Excellence 'Advanced Imaging of Matter' - Structural Dynamics of Surface Catalytic Reactions investigated at X-ray Free-Electron Lasers”

With the new X-ray free-electron lasers in Hamburg, FLASH at DESY and the European XFEL, it is now possible to perform real-time investigations of the geometric structure during surface chemical reactions.


Link to Job Posting


LCLS – SRD Div. Director [Senior/ Distinguished Staff Scientist]

Link to job posting

Job Requisition #: 3370
Classification Title: Staff Scientist- Senior
Location: Menlo Park, CA (HQ)
# of openings: 1

Position Summary


The Linac Coherent Light Source (LCLS) is an internationally preeminent science facility, operated by Stanford University at the SLAC National Accelerator Laboratory on behalf of the Department of Energy, Office of Science. This facility provides world-leading scientific capabilities to a global user community, covering a very broad research portfolio that includes the investigation of advanced materials and chemical catalysts for clean energy systems, drug discovery for modern pharmaceuticals, and fundamental studies of extreme states of matter.

This is a pivotal time for LCLS, and a rare opportunity to shape the scientific nature and direction of the facility. We are nearing completion of LCLS-II, representing more than a billion dollars of investment in a new accelerator complex that will increase the X-ray repetition rate and average power by almost 4 orders of magnitude. LCLS-II will transform our ability to observe electronic and molecular dynamics, with a new suite of end stations being designed to make optimum use of the new sources. A subsequent upgrade to enable the delivery of high energy X-rays (LCLS-II-HE) is also underway, opening up the study of rare, transient and heterogeneous systems with atomic resolution and femtosecond precision. 

LCLS is renowned for driving continual improvements in the capabilities of its X-ray source, instrumentation and associated technologies, coupled to deep engagement with our domestic and international user community to anticipate and meet their scientific needs in the short-term (via experimental delivery) and in the long-term (via prioritized facility development).

We are now seeking a scientific leader who can sustain and enhance these activities for the LCLS-II and LCLS-II-HE era and lead our Science, Research and Development (SRD) Division. Reporting to the Associate Laboratory Director (ALD) for LCLS, the SRD Division Leader provides top-level leadership to our beamline scientists and associated technical areas, including detectors and sample delivery and functions as a member of the LCLS leadership team. This position will also serve as a senior scientist and define research frontiers and directions in the field of X-ray ultrafast science.


  • Provide scientific direction to the group of ~30 LCLS beamline scientists, to guide and develop their careers and maximize the scientific benefit provided to our experimental user program. Oversee all aspects of hiring, performance management and staff development.
  • Oversee and optimize the scientific role of LCLS in the design, planning, execution, analysis and publication of  experiments.
  • Working with the wider LCLS team and user community, identify prioritized research directions for LCLS that will deliver internationally leading results at a scale commensurate with the level of investment and ambition of our laboratory and sponsors. This includes the identification of facility developments, experimental campaigns, and the use of in-house beam time and research activities.
  • Plan, commission and exploit the identified developments, and establish appropriate mechanisms for oversight of optimized deployment, ongoing effectiveness and future improvement to meet the evolving LCLS needs.
  • Drive the continual development of in-house scientific excellence, innovation and adventure in our scientific and technical staff.
  • Foster a highly collaborative, positive, respectful and inclusive culture in all aspects of our work.
  • Arbitrate any proposed changes to the scope of planned or ongoing experiments to optimize scientific impact consistent with operational constraints and the decisions of our peer-review process.
  • Ensure the SRD team has the appropriate staff, skills, knowledge and abilities to deliver its mission both now and in the future – consistent with financial and operational constraints.
  • As part of the LCLS leadership team, and a senior member of SLAC, provide proactive strategic and operational solutions to deliver the wider LCLS/SLAC strategy.
  • Engage all parts of the LCLS user community, including our staff and the local SLAC/Stanford research teams, to solicit advice and active engagement in LCLS scientific objectives, operations and development.
  • Reach out to the wider research community to inform and expand the user base for LCLS to ensure long-term alignment to the nation’s most compelling scientific objectives.
  • Oversee a complete set of robust, fair and productive working practices and processes to achieve the mission of SRD, including delivery of scope consistent with the agreed budget and schedule.
  • Other duties as assigned by LCLS/SLAC management.

NoteThis position is a dual posting at the Senior or Distinguished Staff Scientist level. Where appropriate, consideration may be given to a faculty appointment via a separate parallel assessment process. Appointment at the Senior or Distinguished Staff Scientist level is a regular-continuing position and requires an achieved recognition of leadership internationally, as a result of original developments in field of expertise.

Applicants should include a cover letter, a statement of research including brief summary of accomplishments, a curriculum vitae, a list of publications, and names of three references for future letters of recommendation with the application. Potential applicants who wish to discuss the position in more detail may contact the LCLS Director, Prof Mike Dunne at  This email address is being protected from spambots. You need JavaScript enabled to view it. .


Education & Experience:

Ph.D. in a scientific field strongly related to LCLS science, with at least 10 years of post-Ph.D. professional experience including:

  • Extensive body of research, development, or applied work that is internationally acknowledged to have defined major advancements in research.
  • Substantial experience in delivering complex, multi-year technical projects.
  • Extensive experience leading and managing scientific and technical research groups.
  • Proven record of independent research including publications in major journals and conference presentations in x-ray science

Knowledge, Skills and Abilities:

  • Define research frontiers and directions. Innovate, develop, and apply advanced technical principles, theories, concepts, and highly advanced technologies.
  • Proven ability to mentor junior staff and peers, with a strong focus on career development.
  • Work and communicate effectively with a diverse population.
  • Define, prioritize and deliver a complex portfolio of research programs.
  • Interpersonal skills that can secure the trust of a broad research community and manage any conflicts in a manner that reinforces our strong commitment to a respectful, inclusive and diverse workplace.
  • Successfully manage organizational and cultural change in a complex environment
  • Commitment to safety as an overarching priority.

SLAC Manager Competencies:

  • Team Effectiveness: Effectively motivates team members and fosters a diverse and collaborative team environment; leverages team members’ strengths for overall team effectiveness; incorporates insights to improve team operations.
  • Purpose & Vision: Articulates a clear vision of expected outcomes; inspires others to execute work plans and feel a sense of purpose and ownership for the mission.
  • Builds Trust: Earns trust and credibility from team members, peers and stakeholders; demonstrates SLAC values of respect and integrity.
  • Relationships: Builds relationships to foster trust, collaboration, and a positive climate to achieve team, department/directorate and lab goals.
  • Communication: Ensures effective information flow to various audiences; delivers clear and appropriate written and verbal communications; makes clear and impactful presentations to a variety of internal and external audiences.
  • Navigates Complexity: Manages a multitude of information and complex circumstances to discern what is most important; demonstrates effective problem-solving, decision-making, and takes appropriate action, even in difficult situations or with conflicting data.
  • Results through Others: Achieves expected results by effectively delegating and managing the work of others.
  • Aligns Priorities: Ensures planning and prioritization of resources and work efforts; ensures alignment of direct and matrix reports to support organizational goals and business plans.
  • Applies Lab Acumen: Maintains understanding of lab efforts and direction as well as current research and trends, considers technology and customer impacts, and contributes relevant, informed ideas to lab growth.
  • Self-Awareness: Seeks feedback from others and takes ownership of, and actions to address what is learned; recognizes impact on others and adjusts as needed; pursues continuous learning opportunities; implements a meaningful development plan.


Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.


May work extended hours depending on operational or research needs.


  • Interpersonal Skills: Demonstrates the ability to work well with Stanford colleagues and clients and with external organizations.
  • Promote Culture of Safety: Demonstrates commitment to personal responsibility and value for environment, safety and security; communicates related concerns; uses and promotes safe behaviors based on training and lessons learned.  Meets the applicable roles and responsibilities as described in the ESH Manual, Chapter 1—General Policy and Responsibilities: http://www-group.slac.stanford.edu/esh/eshmanual/pdfs/ESHch01.pdf
  • Subject to and expected to comply with all applicable University policies and procedures, including but not limited to the personnel policies and other policies found in the University's Administrative Guide, http://adminguide.stanford.edu.



College of Letters and Science

Department of Physics                                                                                   

Marius Schmidt                                                                                      


Research Associate Position

September 25, 2018


The Department of Physics at the University of Wisconsin-Milwaukee (UWM) seeks an outstanding candidate for a post-doctoral position in the group of Prof. Marius Schmidt to begin as soon as possible. The successful applicant will become part of an interdisciplinary team at the UWM that aims to solve important biological questions using ultra-brilliant, pulsed X-ray sources such as newest generation synchrotron light sources and the expanding global network of free-electron X-ray laser facilities (XFELs, see e.g. Tenboer et al., 2014, Science; Pande et al. 2016, Science; Olmos et al., 2018, BMC-Biology). The successful candidate will have the opportunity to be productive with significant national and international recognition, collaborate with the team of UWM faculty supported by the BioXFEL National Science Foundation (NFS)-Science and Technology Center (STC), and work collaboratively in the STC - a consortium of eight universities across the U.S. including University of Buffalo, Arizona State, Cornell, Stanford, UCSF, Rice, Miami of Ohio, and UWM. Beamtime opportunities at the LCLS and other XFELs (European XFEL, SwissFEL, SACLA) are available within the group and within the BioXFEL STC network. This is a unique opportunity to enter this highly innovative field of research. Research areas of interest include, but are not limited to: time-resolved crystallography, molecular biology, biophysics, time-resolved optical spectroscopy, X-ray diffraction and imaging, and enzymology. UWM is in the Milwaukee metropolitan area, at Lake Michigan, close to the Chicago greater area. Minimum Qualifications: • Doctorate in (Bio)Physics, Biology, (Bio)Chemistry or a related field. • A demonstrated record of research accomplishments (papers). • Willingness to travel to synchrotrons and free electron X-ray lasers in the US, Europe and Japan to collect data. • Familiarity with use of computers, and basic programming skills are required.

Please also check https://uwm.edu/physics/people/schmidt-marius/ and http://people.uwm.edu/smarius/.

Interested candidates contact, by phone or email: Marius Schmidt, University of Wisconsin-Milwaukee Physics Department, Milwaukee, Wi53211, email: This email address is being protected from spambots. You need JavaScript enabled to view it. , phone +1-414-229-4338.



Postdoctoral Research Scholar (Job # 12921)





The department of Physics at Arizona State University seeks applicants for a postdoctoral research scholar to work in the field of biological sample delivery for X-ray lasers.

The successful applicant will work with the National Science Foundation's BioXFEL Science and Technology Center (STC) (https://www.bioxfel.org), a consortium of six US campuses devoted to the application and development of X-ray lasers for biology. This supports the research programs of seven faculty at ASU, where a compact campus XFEL is under construction. He/she will work under the supervision of Prof J. Spence and collaborate with other BioXFEL faculty, while also conducting original research. This may involve the use of our two-photon 3D printer for microfluidic mixing devices to enable time-resolved X-ray crystallography and solution scattering at XFELs. Applicants should hold a doctorate or equivalent degree in a relevant field of science, such as physics, bioengineering, biophysics, fluid dynamics, microfluidics or chemistry. Applicants are responsible for having three references sent to the address below by the relevant deadline, and also for providing the names of these referees and a CV. More details can be obtained from  This email address is being protected from spambots. You need JavaScript enabled to view it. .

ASU is situated near Phoenix, Arizona, and is one of the largest universities in the United States. Recently ranked as one of the top 100 research universities in the world, its 40 Physics department faculty work mainly in Biophysics, Nano and Materials Science, Cosmology and Particle Astrophysics, and hold many honors (http://physics.asu.edu). It is also home the Beyond Center (http://beyond.asu.edu).

To apply, please send electronically to https://physics.asu.edu/content/postdoctoral-research-scholar-job-12921. The following materials:  a cover letter, a CV, a publication list, and a detailed summary of research experience and interests, and 3 reference letters. Applications should be submitted in one complete attachment. For more information about the position, contact John Spence, John This email address is being protected from spambots. You need JavaScript enabled to view it.

The initial review of applications will begin July 2, 2019 if not filled; applications will be reviewed every week thereafter until the search is closed.

A background check is required for employment.

Arizona State University is a VEVRAA Federal Contractor and an Equal Opportunity Affirmative Action Employer. All qualified applicants will be considered without regard to race, color, sex, religion, national origin, disability, protected veteran status, or any other basis protected by law. https://www.asu.edu/aad/manuals/acd/acd401.html.  https://www.asu.edu/titleIX.

In compliance with federal law, ASU prepares an annual report on campus security and fire safety programs and resources.  ASU’s Annual Security and Fire Safety Report is available online at https://www.asu.edu/police/PDFs/ASU-Clery-Report.pdf. You may request a hard copy of the report by contacting the ASU Police Department at 480-965-3456.