Science

BioXFEL’s mission is to broaden the scientific community’s exposure to the development of new techniques for observing molecular machines. Utilizing the capabilities of X-ray free electron lasers, we will work to develop the tools and software applications needed to expand this knowledge outward. These applications will be applied to a wide range of scientific inquiry, including the studies of photosynthesis, enzyme function at the atomic level and drug-delivery proteins.

OnDA Solution Scattering Monitoring Software

Background description here:

 

Video tutorial

 

FAQs

 

Download link for .pdf of manual.

Beam Times

Serial Crystallography

Serial Crystallography at LCLS - Resources and tutorial

Cheetah

CrystFEL

OnDA

cctbx.xfel

Single Particles

Hawk

Data Archives (Single Particles and Nanocrystals)

CXIDB - Practice Datasets from LCLS

Visualizing Crystallographic Concepts

XRay View

Key for types of experiment:

SFX = serial fs crystallography in liquid jet; LCP SFX = lipidic cubic phase SFX; TR = time resolved; 2DX = 2D crystals; FixT = Fixed target; phasing = shape transforms / high intensity / SAD ; SP = single particle; SAXS/WAXS = small/wide angle X-ray scattering; SMX = serial millisecond crystallography, usually with slow jet at synchrotron; FSS = fast solution scattering ; CSX = correlated Xray scattering; SFD = serial fiber diffraction

BioXFEL Beamtime Archive

X-ray Free Electron Lasers

X-ray Free Electron Lasers (XFEL) produce a stream of unimaginably intense X-rays and in unimaginably short pulses, so intense and so rapid that they can capture the fastest biological processes. X-ray Free Electron Lasers offer a unique and exciting opportunity to explore biological mechanisms in areas that were previously thought impossible.

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Projects

The BioXFEL Center benefits from the research performed at several major universities and laboratories. Here you'll find the descriptions of these projects and the laboratories leading them. 

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