What's New: Past Month


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  1. Exposing Hidden Alternative Backbone Conformations in X-ray Crystallography Using qFit

    Describing the multiple conformations of proteins is important for understanding the relationship between molecular flexibility and function. However, most methods for interpreting data from X-ray …


  2. De novo phasing with X-ray laser reveals mosquito larvicide BinAB structure

    BinAB is a naturally occurring paracrystalline larvicide distributed worldwide to combat the devastating diseases borne by mosquitoes. These crystals are composed of homologous molecules, BinA and …


  3. Structural enzymology using X-ray free electron lasers

    Mix-and-inject serial crystallography (MISC) is a technique designed to image enzyme catalyzed reactions in which small protein crystals are mixed with a substrate just prior to being probed by …


  4. BioXFEL NSF GRFP Workshop Registration


  5. Coherent diffraction of single Rice Dwarf virus particles using hard X-rays at the Linac Coherent Light Source

    For several decades, X-ray crystallography has been the dominant technique to solve the three-dimensional (3D) structure of biological macromolecules at atomic resolution. Structures of proteins, …


  6. Job Opening: Research Specialist

    Arizona State University is currently seeking a research specialist. This position in experimental biophysics would assist scientists in collecting experimental data at the Linac Coherent Light …


  7. Three-dimensional-printed gas dynamic virtual nozzles for x-ray laser sample delivery

    Reliable sample delivery is essential to biological imaging using X-ray Free Electron Lasers (XFELs). Continuous injection using the Gas Dynamic Virtual Nozzle (GDVN) has proven valuable, …


  8. XFEL data analysis for structural biology

    X-ray Free Electron Lasers (XFELs) have advanced research in structure biology, by exploiting their ultra-short and bright X-ray pulses. The resulting “diffraction before destruction” …


  9. Structure solved from smallest protein crystals yet

    The room temperature structure of natively formed protein nanocrystals consisting of 9,000 unit cells has been solved to 2 Å resolution using an unattenuated X-ray free-electron laser (XFEL) beam, …


  10. BioXFEL Opens Interactive Exhibit at the Buffalo Museum of Science

    BioXFEL recently unveiled an installation at the Buffalo Museum of Science. It is located within the exhibit “Our Marvelous Earth”. Visitors can explore the world of crystallography through an …


  11. Markelz receives $1.35 million to study molecules’ vibrations, opening new possibilities for an emerging field

    Molecules vibrate and resonate. These vibrations enable life to function, they are believed to play a role in photosynthesis in plants and protein folding in general. BioXFEL participant and …


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