0 Citation(s)

0 questions (Ask a question)

The Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source

By Raymond G. Sierra, Alexander Batyuk, Zhibin Sun, Andrew Aquila, Mark S. Hunter1, Thomas J. Lane, Mengning Liang, Chun Hong Yoon, Roberto Alonso-Mori, Rebecca Armenta, Jean-Charles Castagna, Michael Hollenbeck, Ted O. Osier, Matt Hayes, Jeff Aldrich, Robin Curtis, Jason E. Koglin, Theodore Rendahl, Evan Rodriguez, Sergio Carbajo, Serge Guillet, Rob Paul, Philip Hart, Kazutaka Nakahara, Gabriella Carini, Hasan Demirci2, E. Han Dao, Brandon Hayes1, Yashas P. Rao, Matthieu Chollet, Yiping Feng, Franklin D. Fuller, Christopher Kupitz1, Takahiro Sato, Matthew H. Seaberg, Sanghoon Song, Tim B. Van Driel, Hasan Yavas, Diling Zhu, Aina E. Cohen, Soichi Wakatsuki, Sébastien Boutet

1. SLAC National Accelerator Laboratory 2. Biosciences Division at SLAC National Accelerator Laboratory

See also

No results found.

Category

BioXFEL Publications

Published on

Type

journal-article

Author

Raymond G. Sierra and Alexander Batyuk and Zhibin Sun and Andrew Aquila and Mark S. Hunter and Thomas J. Lane and Mengning Liang and Chun Hong Yoon and Roberto Alonso-Mori and Rebecca Armenta and Jean-Charles Castagna and Michael Hollenbeck and Ted O. Osier and Matt Hayes and Jeff Aldrich and Robin Curtis and Jason E. Koglin and Theodore Rendahl and Evan Rodriguez and Sergio Carbajo and Serge Guillet and Rob Paul and Philip Hart and Kazutaka Nakahara and Gabriella Carini and Hasan DeMirci and E. Han Dao and Brandon M. Hayes and Yashas P. Rao and Matthieu Chollet and Yiping Feng and Franklin D. Fuller and Christopher Kupitz and Takahiro Sato and Matthew H. Seaberg and Sanghoon Song and Tim B. van Driel and Hasan Yavas and Diling Zhu and Aina E. Cohen and Soichi Wakatsuki and Sébastien Boutet

Citation

Sierra, R.G. et al., 2019. The Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source. Journal of Synchrotron Radiation, 26(2), pp.346–357. Available at: http://dx.doi.org/10.1107/s1600577519001577.

Abstract

The Macromolecular Femtosecond Crystallography (MFX) instrument at the Linac Coherent Light Source (LCLS) is the seventh and newest instrument at the world's first hard X-ray free-electron laser. It was designed with a primary focus on structural biology, employing the ultrafast pulses of X-rays from LCLS at atmospheric conditions to overcome radiation damage limitations in biological measurements. It is also capable of performing various time-resolved measurements. The MFX design consists of a versatile base system capable of supporting multiple methods, techniques and experimental endstations. The primary techniques supported are forward scattering and crystallography, with capabilities for various spectroscopic methods and time-resolved measurements. The location of the MFX instrument allows for utilization of multiplexing methods, increasing user access to LCLS by running multiple experiments simultaneously.

DOI

http://dx.doi.org/10.1107/s1600577519001577