Synthesis, structure, docking and cytotoxic studies of ferrocene–hormone conjugates for hormone-dependent breast cancer application

By José A. Carmona-Negrón, Alberto Santana, Arnold L. Rheingold, Enrique Meléndez

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Type

journal-article

Author

José A. Carmona-Negrón and Alberto Santana and Arnold L. Rheingold and Enrique Meléndez

Citation

Carmona-Negrón, J.A. et al., 2019. Synthesis, structure, docking and cytotoxic studies of ferrocene–hormone conjugates for hormone-dependent breast cancer application. Dalton Transactions. Available at: http://dx.doi.org/10.1039/c8dt01856a.

Abstract

Ferrocene–estrogen conjugates can be recognized by ERα, suggesting that estrogens could serve as vectors to target specifically breast cancer cell lines.

DOI

Funding

NSF-STC Biology with X-ray Lasers (NSF-1231306)