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De novo protein crystal structure determination from X-ray free-electron laser data

08 Jan 2014 | Publications | Contributor(s): K. Nass, S. Botha, G. J. Williams, T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, S. Boutet, I. Schlichting, R. B. Doak, Mark Messerschmidt

The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …

https://www.bioxfel.org/resources/238

Protein structural ensembles are revealed by redefining X-ray electron density noise

06 Jan 2014 | Publications | Contributor(s): T. Alber, J. S. Fraser, P. T. Lang, James Holton

To increase the power of X-ray crystallography to determine not only the structures but also the motions of biomolecules, we developed methods to address two classic crystallographic problems: …

https://www.bioxfel.org/resources/282

Crystallographic data processing for free-electron laser sources

30 Jun 2013 | Publications | Contributor(s): N. A. Zatsepin, F. Stellato, T. A. White, A. Barty, R. A. Kirian, Henry Chapman, James Holton

A processing pipeline for diffraction data acquired using the `serial crystallography' methodology with a free-electron laser source is described with reference to the crystallographic analysis suite …

https://www.bioxfel.org/resources/236

Simultaneous femtosecond X-ray spectroscopy and diffraction of photosystem II at room temperature

25 Apr 2013 | Publications | Contributor(s): S. Gul, J. E. Koglin, P. H. Zwart, C. Glockner, M. J. Latimer, N. K. Sauter, A. R. Fry, W. E. White, J. Sellberg, R. W. Grosse-Kunstleve, G. Han, T. C. Weng, J. Hellmich, R. G. Sierra, D. Milathianaki, S. Boutet, H. Laksmono, P. Glatzel, B. Lassalle-Kaiser, M. J. Bogan, N. Echols, A. Miahnahri, V. K. Yach, J. Messinger, R. Tran, D. W. Schafer, S. Koroidov, J. Hattne, R. Alonso-Mori, D. Difiore, M. M. Seibert, G. J. Williams, P. D. Adams, A. Zouni, J. Yano, A. Lampe, U. Bergmann, J. Kern, R. J. Gildea, D. Sokaras, Mark Messerschmidt, Ranga Setlur

Intense femtosecond x-ray pulses produced at the Linac Coherent Light Source (LCLS) were used for simultaneous x-ray diffraction (XRD) and x-ray emission spectroscopy (XES) of microcrystals of …

https://www.bioxfel.org/resources/293

Crystallography: Sources of inspiration

31 Dec 2012 | Publications | Contributor(s): S. McSweeney, Petra Fromme

2014.

https://www.bioxfel.org/resources/237

Single mimivirus particles intercepted and imaged with an X-ray laser

02 Feb 2011 | Publications | Contributor(s): P. Holl, S. Stern, M. Svenda, R. Hartmann, L. Struder, D. Pietschner, J. Krzywinski, C. Abergel, H. Hirsemann, A. Homke, F. Schopper, S. Herrmann, M. J. Bogan, R. Andritschke, L. Foucar, T. Gorkhover, N. Coppola, J. Andreasson, B. Iwan, G. Williams, A. A. Miahnahri, D. Westphal, C. Y. Hampton, M. Barthelmess, R. L. Shoeman, A. Rocker, G. Potdevin, D. Rupp, J. Schulz, C. Caleman, V. Seltzer, O. Jonsson, S. Schorb, M. M. Seibert, R. G. Sierra, L. Lomb, D. P. DePonte, J. Hajdu, B. Rudek, H. Graafsma, A. Barty, F. R. Maia, S. Boutet, M. Hantke, K. U. Kuhnel, T. Ekeberg, B. Erk, G. Weidenspointner, C. Reich, I. Schlichting, S. W. Epp, R. Kirian, M. Adolph, G. Hauser, D. Rolles, J. M. Claverie, C. Bostedt, H. Soltau, A. Martin, N. Kimmel, S. Marchesini, M. Liang, R. B. Doak, L. Gumprecht, D. Odic, J. D. Bozek, B. Nilsson, H. Gorke, A. Aquila, F. Krasniqi, S. Bajt, M. Bott, K. O. Hodgson, T. A. White, A. Rudenko, G. Schaller, D. Starodub, J. Ullrich, C. D. Schroter, I. Andersson, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …

https://www.bioxfel.org/resources/294

Reconstruction from a single diffraction pattern of azimuthally projected electron density of molecules aligned parallel to a single axis

31 Dec 2009 | Publications | Contributor(s): V. L. Shneerson, D. Starodub, Dilano Saldin, John Spence

Diffraction from the individual molecules of a molecular beam, aligned parallel to a single axis by a strong electric field or other means, has been proposed as a means of structure determination of …

https://www.bioxfel.org/resources/286