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De novo protein crystal structure determination from X-ray free-electron laser data

08 Jan 2014 | Publications | Contributor(s): R. B. Doak, K. Nass, S. Botha, G. J. Williams, T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, S. Boutet, I. Schlichting, Mark Messerschmidt

The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …

https://www.bioxfel.org/resources/238

Protein structural ensembles are revealed by redefining X-ray electron density noise

06 Jan 2014 | Publications | Contributor(s): P. T. Lang, T. Alber, J. S. Fraser, James Holton

To increase the power of X-ray crystallography to determine not only the structures but also the motions of biomolecules, we developed methods to address two classic crystallographic problems: …

https://www.bioxfel.org/resources/282

Crystallographic data processing for free-electron laser sources

30 Jun 2013 | Publications | Contributor(s): R. A. Kirian, N. A. Zatsepin, F. Stellato, T. A. White, A. Barty, Henry Chapman, James Holton

A processing pipeline for diffraction data acquired using the `serial crystallography' methodology with a free-electron laser source is described with reference to the crystallographic analysis suite …

https://www.bioxfel.org/resources/236

Simultaneous femtosecond X-ray spectroscopy and diffraction of photosystem II at room temperature

25 Apr 2013 | Publications | Contributor(s): R. Alonso-Mori, S. Koroidov, C. Glockner, M. J. Latimer, J. E. Koglin, P. D. Adams, J. Sellberg, G. Han, A. R. Fry, U. Bergmann, R. J. Gildea, D. Milathianaki, J. Hellmich, P. H. Zwart, S. Gul, B. Lassalle-Kaiser, M. J. Bogan, H. Laksmono, W. E. White, R. W. Grosse-Kunstleve, N. K. Sauter, J. Messinger, D. W. Schafer, A. Miahnahri, R. G. Sierra, T. C. Weng, D. Difiore, M. M. Seibert, J. Hattne, S. Boutet, P. Glatzel, J. Yano, G. J. Williams, A. Zouni, V. K. Yach, R. Tran, N. Echols, J. Kern, D. Sokaras, A. Lampe, Mark Messerschmidt, Ranga Setlur

Intense femtosecond x-ray pulses produced at the Linac Coherent Light Source (LCLS) were used for simultaneous x-ray diffraction (XRD) and x-ray emission spectroscopy (XES) of microcrystals of …

https://www.bioxfel.org/resources/293

Crystallography: Sources of inspiration

31 Dec 2012 | Publications | Contributor(s): S. McSweeney, Petra Fromme

2014.

https://www.bioxfel.org/resources/237

Single mimivirus particles intercepted and imaged with an X-ray laser

02 Feb 2011 | Publications | Contributor(s): R. Kirian, M. Adolph, S. W. Epp, J. Schulz, B. Rudek, A. Barty, G. Potdevin, D. P. DePonte, L. Gumprecht, N. Kimmel, S. Marchesini, M. Liang, R. B. Doak, B. Erk, H. Graafsma, F. R. Maia, C. Reich, J. Hajdu, S. Bajt, M. Bott, K. O. Hodgson, T. A. White, D. Rolles, C. Bostedt, I. Schlichting, A. Martin, G. Weidenspointner, R. Hartmann, L. Struder, P. Holl, S. Stern, M. Svenda, B. Nilsson, H. Soltau, A. Aquila, G. Hauser, D. Odic, J. M. Claverie, T. Gorkhover, N. Coppola, S. Herrmann, M. J. Bogan, R. Andritschke, L. Foucar, H. Gorke, D. Starodub, F. Krasniqi, C. D. Schroter, J. D. Bozek, A. Rudenko, R. L. Shoeman, M. Barthelmess, D. Pietschner, J. Ullrich, C. Abergel, I. Andersson, A. Homke, G. Schaller, L. Lomb, V. Seltzer, O. Jonsson, S. Schorb, M. M. Seibert, R. G. Sierra, B. Iwan, H. Hirsemann, A. A. Miahnahri, F. Schopper, C. Y. Hampton, J. Krzywinski, T. Ekeberg, S. Boutet, M. Hantke, K. U. Kuhnel, D. Rupp, D. Westphal, C. Caleman, J. Andreasson, A. Rocker, G. Williams, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …

https://www.bioxfel.org/resources/294

Reconstruction from a single diffraction pattern of azimuthally projected electron density of molecules aligned parallel to a single axis

31 Dec 2009 | Publications | Contributor(s): V. L. Shneerson, D. Starodub, Dilano Saldin, John Spence

Diffraction from the individual molecules of a molecular beam, aligned parallel to a single axis by a strong electric field or other means, has been proposed as a means of structure determination of …

https://www.bioxfel.org/resources/286