Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): R. B. Doak, C. Reich, H. Bottin, A. Hartmann, K. Nass, F. Krasniqi, J. Andreasson, S. Stern, L. Lomb, M. M. Seibert, J. Ullrich, S. a. Bajt, D. Rolles, P. Holl, B. Rudek, J. Davidsson, R. L. Shoeman, C. Y. Hampton, H. Graafsma, N. Coppola, A. Rudenko, L. Foucar, M. Barthelmess, F. Stellato, C. Caleman, G. Weidenspointner, A. Barty, S. Marchesini, E. Malmerberg, I. Schlichting, R. A. Kirian, X. Wang, L. Johansson, M. Liang, G. n. Hauser, J. Schulz, R. Sierra, D. P. DePonte, H. Soltau, N. Timneanu, B. Erk, T. R. M. Barends, J. D. Bozek, R. Hartmann, C. Wunderer, H. Fleckenstein, A. Hˆmke, K.-U. K¸hnel, L. Str¸der, F. R. N. C. Maia, S. W. Epp, A. Aquila, S. Kassemeyer, D. Starodub, I. Grotjohann, C. Bostedt, V. Elser, G. J. Williams, J. Hajdu, R. Neutze, D. Arnlund, H. Hirsemann, N. Kimmel, A. V. Martin, L. Gumprecht, M. J. Bogan, T. A. White, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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