Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): C. Reich, A. Hartmann, I. Schlichting, F. Krasniqi, G. Weidenspointner, S. Marchesini, R. A. Kirian, H. Soltau, X. Wang, D. Rolles, L. Johansson, B. Rudek, J. Schulz, M. Liang, R. Sierra, N. Timneanu, T. R. M. Barends, C. Y. Hampton, K.-U. K¸hnel, A. Rudenko, J. D. Bozek, F. Stellato, H. Fleckenstein, R. Hartmann, L. Str¸der, A. Barty, I. Grotjohann, E. Malmerberg, S. W. Epp, C. Caleman, S. Kassemeyer, G. n. Hauser, H. Hirsemann, V. Elser, D. P. DePonte, L. Gumprecht, B. Erk, J. Hajdu, R. Neutze, N. Kimmel, M. J. Bogan, C. Wunderer, K. Nass, A. Hˆmke, J. Andreasson, F. R. N. C. Maia, H. Bottin, T. A. White, R. B. Doak, A. Aquila, D. Starodub, L. Lomb, S. Stern, C. Bostedt, J. Ullrich, M. M. Seibert, S. a. Bajt, P. Holl, D. Arnlund, L. Foucar, A. V. Martin, J. Davidsson, G. J. Williams, H. Graafsma, R. L. Shoeman, N. Coppola, M. Barthelmess, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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