Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): P. Holl, K.-U. K¸hnel, M. M. Seibert, J. D. Bozek, S. a. Bajt, H. Fleckenstein, F. Krasniqi, C. Reich, A. Hartmann, M. Barthelmess, I. Grotjohann, R. L. Shoeman, N. Coppola, X. Wang, B. Rudek, D. Rolles, R. A. Kirian, L. Gumprecht, J. Hajdu, S. Marchesini, H. Hirsemann, F. Stellato, C. Y. Hampton, T. R. M. Barends, A. Rudenko, N. Timneanu, K. Nass, M. Liang, J. Andreasson, R. Sierra, H. Bottin, E. Malmerberg, C. Caleman, S. W. Epp, A. Barty, L. Str¸der, R. Hartmann, L. Lomb, J. Ullrich, V. Elser, B. Erk, G. n. Hauser, D. P. DePonte, L. Foucar, J. Davidsson, S. Kassemeyer, H. Graafsma, F. R. N. C. Maia, C. Wunderer, T. A. White, A. Hˆmke, M. J. Bogan, I. Schlichting, R. Neutze, G. Weidenspointner, N. Kimmel, C. Bostedt, S. Stern, A. Aquila, D. Starodub, H. Soltau, R. B. Doak, L. Johansson, J. Schulz, G. J. Williams, D. Arnlund, A. V. Martin, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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