Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): G. Weidenspointner, R. Sierra, A. Hartmann, N. Timneanu, F. Krasniqi, I. Schlichting, M. Liang, C. Reich, T. R. M. Barends, J. Schulz, D. Rolles, H. Soltau, L. Str¸der, B. Rudek, L. Johansson, R. Hartmann, S. W. Epp, C. Y. Hampton, H. Fleckenstein, S. Kassemeyer, A. Rudenko, K.-U. K¸hnel, F. Stellato, J. D. Bozek, V. Elser, R. Neutze, A. Barty, N. Kimmel, E. Malmerberg, I. Grotjohann, M. J. Bogan, C. Caleman, T. A. White, J. Hajdu, D. P. DePonte, H. Hirsemann, B. Erk, L. Gumprecht, R. B. Doak, G. n. Hauser, S. Stern, H. Bottin, S. a. Bajt, A. Hˆmke, K. Nass, P. Holl, F. R. N. C. Maia, J. Andreasson, M. M. Seibert, C. Wunderer, A. Aquila, J. Ullrich, N. Coppola, D. Starodub, M. Barthelmess, C. Bostedt, L. Lomb, R. L. Shoeman, D. Arnlund, H. Graafsma, S. Marchesini, A. V. Martin, L. Foucar, R. A. Kirian, G. J. Williams, J. Davidsson, X. Wang, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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