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Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals

28 Feb 2011 | Publications | Contributor(s): X. Wang, A. V. Martin, L. Lomb, T. A. White, A. Barty, F. R. Maia, R. A. Kirian, A. Aquila, Henry Chapman, Petra Fromme, James Holton, Mark S. Hunter, Marius Schmidt, John Spence

A complete set of structure factors has been extracted from hundreds of thousands of femtosecond single-shot X-ray microdiffraction patterns taken from randomly oriented nanocrystals. The method of …

https://www.bioxfel.org/resources/Structure-factor-analysis-of-femtosecond-microdiffraction

Femtosecond X-ray protein nanocrystallography

02 Feb 2011 | Publications | Contributor(s): G. Weidenspointner, I. Schlichting, L. Gumprecht, R. L. Shoeman, F. R. Maia, N. Timneanu, C. Reich, M. M. Seibert, A. Rudenko, S. W. Epp, J. Schulz, G. J. Williams, D. Rupp, C. Bostedt, M. Bott, A. Barty, S. Marchesini, R. Andritschke, H. Graafsma, K. U. Kuhnel, J. D. Bozek, B. Erk, T. A. White, L. Struder, S. Bajt, G. Hauser, P. Holl, D. P. DePonte, G. Schaller, I. Grotjohann, R. Hartmann, F. Krasniqi, N. Kimmel, C. D. Schroter, M. Liang, A. Rocker, S. Stern, J. Krzywinski, H. Soltau, B. Rudek, T. R. Barends, M. Barthelmess, A. Aquila, S. Herrmann, R. A. Kirian, D. Rolles, H. Gorke, K. Nass, J. Andreasson, A. V. Martin, L. Lomb, R. Neutze, F. Schopper, O. Jonsson, C. Y. Hampton, M. Svenda, J. Ullrich, I. Andersson, G. Potdevin, R. G. Sierra, D. Starodub, N. Coppola, C. Caleman, X. Wang, M. J. Bogan, A. Homke, S. Schorb, R. B. Doak, J. Hajdu, H. Hirsemann, L. Foucar, B. Nilsson, T. Gorkhover, M. Adolph, S. Boutet, D. Pietschner, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …

https://www.bioxfel.org/resources/Femtosecond-X-ray-protein-nanocrystallography

X-ray diffraction from membrane protein nanocrystals

04 Jan 2011 | Publications | Contributor(s): D. P. DePonte, R. A. Kirian, D. A. Shapiro, S. Marchesini, D. Starodub, X. Wang, R. B. Doak, Petra Fromme, Mark S. Hunter, John Spence, Uwe Weierstall

Membrane proteins constitute > 30% of the proteins in an average cell, and yet the number of currently known structures of unique membrane proteins is < 300. To develop new concepts for membrane …

https://www.bioxfel.org/resources/X-ray-diffraction-from-membrane-protein