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Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals

28 Feb 2011 | Publications | Contributor(s): A. Barty, R. A. Kirian, F. R. Maia, A. Aquila, X. Wang, A. V. Martin, L. Lomb, T. A. White, Henry Chapman, Petra Fromme, James Holton, Mark S. Hunter, Marius Schmidt, John Spence

A complete set of structure factors has been extracted from hundreds of thousands of femtosecond single-shot X-ray microdiffraction patterns taken from randomly oriented nanocrystals. The method of …

https://www.bioxfel.org/resources/Structure-factor-analysis-of-femtosecond-microdiffraction

Femtosecond X-ray protein nanocrystallography

02 Feb 2011 | Publications | Contributor(s): L. Gumprecht, J. Andreasson, N. Timneanu, T. R. Barends, H. Gorke, M. M. Seibert, S. Herrmann, K. Nass, C. Bostedt, A. Barty, D. Rupp, I. Andersson, G. Potdevin, M. Bott, R. Neutze, J. Ullrich, R. Andritschke, G. Hauser, D. P. DePonte, B. Erk, L. Foucar, L. Struder, R. G. Sierra, J. Hajdu, P. Holl, X. Wang, H. Hirsemann, S. Schorb, C. D. Schroter, A. Rocker, F. Krasniqi, I. Schlichting, N. Kimmel, T. Gorkhover, G. Weidenspointner, M. Liang, S. Boutet, B. Rudek, A. Aquila, D. Rolles, S. W. Epp, G. J. Williams, M. Barthelmess, R. L. Shoeman, J. Schulz, R. A. Kirian, F. Schopper, C. Y. Hampton, A. V. Martin, K. U. Kuhnel, L. Lomb, J. D. Bozek, O. Jonsson, H. Graafsma, M. Svenda, S. Marchesini, C. Caleman, A. Homke, D. Starodub, I. Grotjohann, N. Coppola, T. A. White, G. Schaller, M. J. Bogan, S. Bajt, R. B. Doak, D. Pietschner, B. Nilsson, S. Stern, M. Adolph, R. Hartmann, J. Krzywinski, H. Soltau, F. R. Maia, C. Reich, A. Rudenko, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …

https://www.bioxfel.org/resources/Femtosecond-X-ray-protein-nanocrystallography

X-ray diffraction from membrane protein nanocrystals

04 Jan 2011 | Publications | Contributor(s): D. A. Shapiro, S. Marchesini, X. Wang, D. Starodub, R. B. Doak, D. P. DePonte, R. A. Kirian, Petra Fromme, Mark S. Hunter, John Spence, Uwe Weierstall

Membrane proteins constitute > 30% of the proteins in an average cell, and yet the number of currently known structures of unique membrane proteins is < 300. To develop new concepts for membrane …

https://www.bioxfel.org/resources/X-ray-diffraction-from-membrane-protein