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Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals

28 Feb 2011 | Publications | Contributor(s): X. Wang, A. V. Martin, L. Lomb, T. A. White, A. Barty, R. A. Kirian, F. R. Maia, A. Aquila, Henry Chapman, Petra Fromme, James Holton, Mark S. Hunter, Marius Schmidt, John Spence

A complete set of structure factors has been extracted from hundreds of thousands of femtosecond single-shot X-ray microdiffraction patterns taken from randomly oriented nanocrystals. The method of …

https://www.bioxfel.org/resources/Structure-factor-analysis-of-femtosecond-microdiffraction

Femtosecond X-ray protein nanocrystallography

02 Feb 2011 | Publications | Contributor(s): X. Wang, S. Schorb, R. G. Sierra, F. Schopper, M. Barthelmess, G. J. Williams, C. Y. Hampton, R. A. Kirian, J. Schulz, A. V. Martin, T. Gorkhover, S. Boutet, D. Starodub, L. Lomb, K. U. Kuhnel, C. Caleman, O. Jonsson, J. D. Bozek, A. Homke, M. Svenda, H. Graafsma, R. L. Shoeman, S. W. Epp, B. Nilsson, N. Coppola, I. Grotjohann, M. J. Bogan, G. Schaller, D. Pietschner, R. B. Doak, S. Marchesini, H. Soltau, F. R. Maia, M. Adolph, C. Reich, J. Krzywinski, A. Rudenko, S. Bajt, T. A. White, L. Gumprecht, K. Nass, C. Bostedt, N. Timneanu, J. Andreasson, A. Barty, M. M. Seibert, H. Gorke, D. Rupp, R. Hartmann, S. Stern, B. Erk, I. Andersson, G. Hauser, M. Bott, G. Potdevin, D. P. DePonte, R. Andritschke, J. Ullrich, T. R. Barends, S. Herrmann, F. Krasniqi, L. Struder, L. Foucar, C. D. Schroter, P. Holl, J. Hajdu, A. Rocker, H. Hirsemann, R. Neutze, B. Rudek, N. Kimmel, I. Schlichting, A. Aquila, M. Liang, G. Weidenspointner, D. Rolles, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …

https://www.bioxfel.org/resources/Femtosecond-X-ray-protein-nanocrystallography

X-ray diffraction from membrane protein nanocrystals

04 Jan 2011 | Publications | Contributor(s): X. Wang, D. Starodub, R. B. Doak, D. P. DePonte, R. A. Kirian, S. Marchesini, D. A. Shapiro, Petra Fromme, Mark S. Hunter, John Spence, Uwe Weierstall

Membrane proteins constitute > 30% of the proteins in an average cell, and yet the number of currently known structures of unique membrane proteins is < 300. To develop new concepts for membrane …

https://www.bioxfel.org/resources/X-ray-diffraction-from-membrane-protein