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Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals

28 Feb 2011 | Publications | Contributor(s): A. Barty, R. A. Kirian, F. R. Maia, A. Aquila, X. Wang, A. V. Martin, L. Lomb, T. A. White, Henry Chapman, Petra Fromme, James Holton, Mark S. Hunter, Marius Schmidt, John Spence

A complete set of structure factors has been extracted from hundreds of thousands of femtosecond single-shot X-ray microdiffraction patterns taken from randomly oriented nanocrystals. The method of …

https://www.bioxfel.org/resources/Structure-factor-analysis-of-femtosecond-microdiffraction

Femtosecond X-ray protein nanocrystallography

02 Feb 2011 | Publications | Contributor(s): C. Bostedt, G. Weidenspointner, A. Barty, D. Rupp, I. Schlichting, M. Liang, T. Gorkhover, S. Boutet, N. Kimmel, G. Hauser, J. Schulz, D. P. DePonte, B. Erk, G. J. Williams, M. Barthelmess, S. W. Epp, R. A. Kirian, R. L. Shoeman, F. Krasniqi, J. D. Bozek, C. D. Schroter, H. Graafsma, A. Rocker, K. U. Kuhnel, O. Jonsson, M. Svenda, L. Lomb, S. Marchesini, B. Rudek, G. Schaller, A. Aquila, D. Rolles, I. Grotjohann, M. J. Bogan, T. A. White, R. B. Doak, S. Bajt, N. Coppola, F. Schopper, J. Krzywinski, C. Y. Hampton, H. Soltau, A. V. Martin, S. Stern, R. Hartmann, M. Adolph, C. Caleman, H. Gorke, A. Homke, K. Nass, D. Starodub, J. Andreasson, N. Timneanu, M. M. Seibert, T. R. Barends, L. Gumprecht, S. Herrmann, B. Nilsson, G. Potdevin, J. Ullrich, D. Pietschner, I. Andersson, M. Bott, R. Andritschke, R. Neutze, F. R. Maia, J. Hajdu, C. Reich, H. Hirsemann, A. Rudenko, L. Foucar, S. Schorb, P. Holl, R. G. Sierra, X. Wang, L. Struder, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …

https://www.bioxfel.org/resources/Femtosecond-X-ray-protein-nanocrystallography

X-ray diffraction from membrane protein nanocrystals

04 Jan 2011 | Publications | Contributor(s): D. P. DePonte, R. A. Kirian, S. Marchesini, D. A. Shapiro, X. Wang, D. Starodub, R. B. Doak, Petra Fromme, Mark S. Hunter, John Spence, Uwe Weierstall

Membrane proteins constitute > 30% of the proteins in an average cell, and yet the number of currently known structures of unique membrane proteins is < 300. To develop new concepts for membrane …

https://www.bioxfel.org/resources/X-ray-diffraction-from-membrane-protein