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Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals

28 Feb 2011 | Publications | Contributor(s): A. V. Martin, L. Lomb, T. A. White, A. Barty, F. R. Maia, R. A. Kirian, A. Aquila, X. Wang, Henry Chapman, Petra Fromme, James Holton, Mark S. Hunter, Marius Schmidt, John Spence

A complete set of structure factors has been extracted from hundreds of thousands of femtosecond single-shot X-ray microdiffraction patterns taken from randomly oriented nanocrystals. The method of …

https://www.bioxfel.org/resources/Structure-factor-analysis-of-femtosecond-microdiffraction

Femtosecond X-ray protein nanocrystallography

02 Feb 2011 | Publications | Contributor(s): A. Aquila, J. Andreasson, O. Jonsson, H. Gorke, D. Rolles, M. Svenda, B. Rudek, K. Nass, L. Lomb, S. Marchesini, N. Coppola, G. Potdevin, C. Y. Hampton, M. J. Bogan, A. V. Martin, J. Ullrich, R. B. Doak, I. Andersson, F. Schopper, T. A. White, S. Bajt, M. Adolph, A. Homke, J. Hajdu, H. Hirsemann, D. Starodub, C. Caleman, L. Foucar, R. Hartmann, S. Stern, N. Timneanu, G. Weidenspointner, D. Pietschner, M. M. Seibert, B. Nilsson, L. Gumprecht, I. Schlichting, T. R. Barends, S. Herrmann, G. J. Williams, C. Reich, M. Bott, A. Rudenko, J. Schulz, R. Andritschke, F. R. Maia, R. Neutze, L. Struder, A. Barty, J. D. Bozek, P. Holl, H. Graafsma, D. Rupp, C. Bostedt, K. U. Kuhnel, R. G. Sierra, X. Wang, S. Schorb, N. Kimmel, G. Schaller, D. P. DePonte, M. Liang, B. Erk, I. Grotjohann, G. Hauser, T. Gorkhover, S. Boutet, M. Barthelmess, A. Rocker, J. Krzywinski, R. A. Kirian, H. Soltau, F. Krasniqi, C. D. Schroter, S. W. Epp, R. L. Shoeman, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …

https://www.bioxfel.org/resources/Femtosecond-X-ray-protein-nanocrystallography

X-ray diffraction from membrane protein nanocrystals

04 Jan 2011 | Publications | Contributor(s): D. Starodub, X. Wang, R. B. Doak, D. P. DePonte, R. A. Kirian, D. A. Shapiro, S. Marchesini, Petra Fromme, Mark S. Hunter, John Spence, Uwe Weierstall

Membrane proteins constitute > 30% of the proteins in an average cell, and yet the number of currently known structures of unique membrane proteins is < 300. To develop new concepts for membrane …

https://www.bioxfel.org/resources/X-ray-diffraction-from-membrane-protein