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Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals

28 Feb 2011 | Publications | Contributor(s): R. A. Kirian, F. R. Maia, A. Aquila, X. Wang, A. V. Martin, L. Lomb, T. A. White, A. Barty, Henry Chapman, Petra Fromme, James Holton, Mark S. Hunter, Marius Schmidt, John Spence

A complete set of structure factors has been extracted from hundreds of thousands of femtosecond single-shot X-ray microdiffraction patterns taken from randomly oriented nanocrystals. The method of …

https://www.bioxfel.org/resources/Structure-factor-analysis-of-femtosecond-microdiffraction

Femtosecond X-ray protein nanocrystallography

02 Feb 2011 | Publications | Contributor(s): D. P. DePonte, M. Barthelmess, B. Erk, R. A. Kirian, G. Hauser, G. J. Williams, T. A. White, J. Schulz, S. Bajt, L. Lomb, A. Rocker, O. Jonsson, F. Krasniqi, M. Svenda, C. D. Schroter, J. D. Bozek, R. Hartmann, H. Graafsma, K. U. Kuhnel, S. Stern, N. Coppola, D. Rolles, M. J. Bogan, B. Rudek, R. B. Doak, A. Aquila, G. Schaller, T. R. Barends, S. Herrmann, I. Grotjohann, M. Adolph, A. V. Martin, F. Schopper, C. Y. Hampton, J. Krzywinski, R. Neutze, H. Soltau, A. Homke, N. Timneanu, D. Starodub, M. M. Seibert, C. Caleman, L. Gumprecht, J. Andreasson, R. G. Sierra, H. Gorke, X. Wang, K. Nass, S. Schorb, D. Pietschner, M. Bott, B. Nilsson, R. Andritschke, G. Potdevin, T. Gorkhover, J. Ullrich, S. Boutet, I. Andersson, L. Struder, A. Rudenko, P. Holl, F. R. Maia, C. Reich, J. Hajdu, R. L. Shoeman, H. Hirsemann, L. Foucar, S. W. Epp, N. Kimmel, D. Rupp, M. Liang, C. Bostedt, A. Barty, G. Weidenspointner, S. Marchesini, I. Schlichting, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …

https://www.bioxfel.org/resources/Femtosecond-X-ray-protein-nanocrystallography

X-ray diffraction from membrane protein nanocrystals

04 Jan 2011 | Publications | Contributor(s): R. A. Kirian, S. Marchesini, D. A. Shapiro, D. Starodub, X. Wang, R. B. Doak, D. P. DePonte, Petra Fromme, Mark S. Hunter, John Spence, Uwe Weierstall

Membrane proteins constitute > 30% of the proteins in an average cell, and yet the number of currently known structures of unique membrane proteins is < 300. To develop new concepts for membrane …

https://www.bioxfel.org/resources/X-ray-diffraction-from-membrane-protein