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Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals

28 Feb 2011 | Publications | Contributor(s): A. Aquila, X. Wang, A. V. Martin, L. Lomb, T. A. White, A. Barty, R. A. Kirian, F. R. Maia, Henry Chapman, Petra Fromme, James Holton, Mark S. Hunter, Marius Schmidt, John Spence

A complete set of structure factors has been extracted from hundreds of thousands of femtosecond single-shot X-ray microdiffraction patterns taken from randomly oriented nanocrystals. The method of …

https://www.bioxfel.org/resources/Structure-factor-analysis-of-femtosecond-microdiffraction

Femtosecond X-ray protein nanocrystallography

02 Feb 2011 | Publications | Contributor(s): A. Rocker, S. Herrmann, G. Schaller, F. Krasniqi, C. D. Schroter, T. R. Barends, I. Grotjohann, L. Lomb, O. Jonsson, M. Svenda, R. Neutze, D. Rolles, J. Krzywinski, B. Rudek, H. Soltau, A. Aquila, N. Coppola, M. J. Bogan, R. B. Doak, C. Y. Hampton, X. Wang, J. Andreasson, A. V. Martin, S. Schorb, H. Gorke, R. G. Sierra, F. Schopper, K. Nass, M. Adolph, A. Homke, S. Boutet, G. Potdevin, D. Starodub, J. Ullrich, C. Caleman, T. Gorkhover, I. Andersson, N. Timneanu, M. M. Seibert, L. Gumprecht, L. Foucar, D. Pietschner, J. Hajdu, B. Nilsson, S. W. Epp, H. Hirsemann, R. L. Shoeman, M. Bott, R. Andritschke, I. Schlichting, A. Rudenko, S. Marchesini, G. Weidenspointner, F. R. Maia, C. Reich, L. Struder, P. Holl, A. Barty, S. Bajt, G. J. Williams, D. Rupp, J. Schulz, C. Bostedt, T. A. White, N. Kimmel, M. Liang, D. P. DePonte, J. D. Bozek, B. Erk, S. Stern, H. Graafsma, R. Hartmann, G. Hauser, K. U. Kuhnel, M. Barthelmess, R. A. Kirian, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall

X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …

https://www.bioxfel.org/resources/Femtosecond-X-ray-protein-nanocrystallography

X-ray diffraction from membrane protein nanocrystals

04 Jan 2011 | Publications | Contributor(s): D. A. Shapiro, S. Marchesini, X. Wang, D. Starodub, R. B. Doak, D. P. DePonte, R. A. Kirian, Petra Fromme, Mark S. Hunter, John Spence, Uwe Weierstall

Membrane proteins constitute > 30% of the proteins in an average cell, and yet the number of currently known structures of unique membrane proteins is < 300. To develop new concepts for membrane …

https://www.bioxfel.org/resources/X-ray-diffraction-from-membrane-protein