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Serial femtosecond crystallography of G protein-coupled receptors

19 Dec 2013 | Publications | Contributor(s): S. Basu, J. E. Koglin, N. A. Zatsepin, V. Katritch, M. Caffrey, S. T. Shah, D. Wang, R. A. Kirian, W. Liu, R. C. Stevens, C. Wang, I. Grotjohann, A. Barty, K. R. Beyerlein, G. W. Han, S. Boutet, D. Wacker, C. Gati, M. M. Seibert, T. A. White, K. N. Rendek, G. J. Williams, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall

X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …

https://www.bioxfel.org/resources/Serial-femtosecond-crystallography-of-G

Simultaneous femtosecond X-ray spectroscopy and diffraction of photosystem II at room temperature

25 Apr 2013 | Publications | Contributor(s): A. Zouni, N. K. Sauter, J. Yano, W. E. White, G. J. Williams, R. W. Grosse-Kunstleve, J. Kern, T. C. Weng, D. Sokaras, R. G. Sierra, A. Lampe, J. E. Koglin, S. Boutet, C. Glockner, P. Glatzel, M. J. Latimer, A. R. Fry, N. Echols, J. Sellberg, V. K. Yach, G. Han, R. Tran, J. Hellmich, S. Koroidov, D. Milathianaki, R. Alonso-Mori, B. Lassalle-Kaiser, P. D. Adams, M. J. Bogan, H. Laksmono, A. Miahnahri, J. Messinger, U. Bergmann, D. W. Schafer, R. J. Gildea, J. Hattne, S. Gul, D. Difiore, P. H. Zwart, M. M. Seibert, Mark Messerschmidt, Ranga Setlur

Intense femtosecond x-ray pulses produced at the Linac Coherent Light Source (LCLS) were used for simultaneous x-ray diffraction (XRD) and x-ray emission spectroscopy (XES) of microcrystals of …

https://www.bioxfel.org/resources/Simultaneous-femtosecond-X-ray-spectroscopy-and

Crystallography: Sources of inspiration

31 Dec 2012 | Publications | Contributor(s): S. McSweeney, Petra Fromme

2014.

https://www.bioxfel.org/resources/Crystallography:-Sources-of-inspiration

High-resolution protein structure determination by serial femtosecond crystallography

19 Jul 2012 | Publications | Contributor(s): W. Ghonsalves, M. W. Tate, L. C. Johansson, G. Haller, C. Kenney, J. Pines, T. A. White, M. J. Bogan, R. Neutze, N. van Bakel, A. Barty, I. Schlichting, D. Schafer, R. B. Doak, S. Boutet, L. Lomb, G. Katona, M. M. Seibert, K. Nass, P. Hart, C. Caleman, J. Morse, F. Stellato, M. Hromalik, R. L. Shoeman, N. Timneanu, S. M. Gruner, A. Aquila, D. P. DePonte, R. A. Kirian, L. J. Koerner, G. J. Williams, C. Y. Hampton, J. Steinbrener, T. R. Barends, M. Liang, P. A. Montanez, A. V. Martin, J. Defever, D. Wang, R. Herbst, N. A. Zatsepin, S. Kassemeyer, L. Redecke, H. T. Philipp, D. Arnlund, Henry Chapman, Petra Fromme, Mark S. Hunter, Christopher Kupitz, Mark Messerschmidt, John Spence, Uwe Weierstall

Structure determination of proteins and other macromolecules has historically required the growth of high-quality crystals sufficiently large to diffract x-rays efficiently while withstanding …

https://www.bioxfel.org/resources/High-resolution-protein-structure-determination-by

In vivo protein crystallization opens new routes in structural biology

29 Feb 2012 | Publications | Contributor(s): L. Struder, J. Ullrich, X. Wang, H. Soltau, S. Boutet, C. Y. Hampton, A. V. Martin, G. Weidenspointner, N. Kimmel, J. Davidsson, T. Ekeberg, M. M. Seibert, R. Koopmann, L. Gumprecht, A. Barty, F. Stellato, C. Bostedt, S. Stern, M. Duszenko, R. B. Doak, K. Cupelli, I. Schlichting, D. Rehders, B. Rudek, H. Graafsma, P. Holl, J. Schulz, H. Hirsemann, S. Bajt, L. Redecke, A. Rudenko, G. J. Williams, C. Reich, J. D. Bozek, T. A. White, M. Liang, R. Hartmann, L. Foucar, N. Coppola, A. Aquila, F. R. Maia, C. Betzel, S. Kassemeyer, M. Barthelmess, R. A. Kirian, D. P. Deponte, B. Erk, H. Fleckenstein, N. Timneanu, J. Hajdu, T. Stehle, R. L. Shoeman, L. Lomb, A. Hartmann, G. Hauser, C. Caleman, S. W. Epp, M. J. Bogan, R. G. Sierra, K. Nass, J. Andreasson, D. Rolles, C. B. Wunderer, Henry Chapman, Petra Fromme, Mark S. Hunter, Mark Messerschmidt, John Spence, Uwe Weierstall

Protein crystallization in cells has been observed several times in nature. However, owing to their small size these crystals have not yet been used for X-ray crystallographic analysis.

https://www.bioxfel.org/resources/In-vivo-protein-crystallization-opens