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Breaking the radiation damage limit with Cryo-SAXS
07 Jan 2013 | Publications | Contributor(s): H. Chen, R. E. Thorne, R. E. Gillilan, J. B. Hopkins, S. P. Meisburger, M. Warkentin, Lois Pollack
Small angle x-ray scattering (SAXS) is a versatile and widely used technique for obtaining low-resolution structures of macromolecules and complexes. SAXS experiments measure molecules in solution, …
https://www.bioxfel.org/resources/228
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Small-angle X-ray scattering and single-molecule FRET spectroscopy produce highly divergent views of the low-denaturant unfolded state
03 May 2012 | Publications | Contributor(s): G. Haran, T. R. Sosnick, K. Plaxco, S. P. Meisburger, J. Hinshaw, T. Y. Yoo, Lois Pollack
The results of more than a dozen single-molecule Forster resonance energy transfer (smFRET) experiments suggest that chemically unfolded polypeptides invariably collapse from an expanded random coil …
https://www.bioxfel.org/resources/297
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Purification and SAXS analysis of the integrin linked kinase, PINCH, parvin (IPP) heterotrimeric complex
31 Dec 2011 | Publications | Contributor(s): A. L. Stiegler, T. J. Boggon, D. A. Calderwood, Tom Grant, Joseph Luft, Edward Snell
The heterotrimeric protein complex containing the integrin linked kinase (ILK), parvin, and PINCH proteins, termed the IPP complex, is an essential component of focal adhesions, where it interacts …
https://www.bioxfel.org/resources/283
