Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): G. Weidenspointner, I. Schlichting, S. Stern, A. V. Martin, P. Holl, G. J. Williams, M. M. Seibert, D. Arnlund, S. a. Bajt, J. Schulz, H. Soltau, L. Johansson, N. Coppola, F. Krasniqi, M. Barthelmess, C. Reich, R. L. Shoeman, A. Hartmann, H. Fleckenstein, K.-U. K¸hnel, J. D. Bozek, D. Rolles, S. Marchesini, B. Rudek, R. A. Kirian, I. Grotjohann, A. Rudenko, N. Timneanu, F. Stellato, M. Liang, X. Wang, C. Y. Hampton, R. Sierra, J. Hajdu, H. Hirsemann, L. Gumprecht, E. Malmerberg, L. Str¸der, T. R. M. Barends, C. Caleman, R. Hartmann, A. Barty, H. Bottin, K. Nass, J. Andreasson, D. P. DePonte, S. Kassemeyer, S. W. Epp, B. Erk, G. n. Hauser, J. Ullrich, L. Lomb, A. Hˆmke, N. Kimmel, F. R. N. C. Maia, M. J. Bogan, V. Elser, C. Wunderer, R. Neutze, J. Davidsson, H. Graafsma, L. Foucar, D. Starodub, T. A. White, C. Bostedt, R. B. Doak, A. Aquila, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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