Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): E. Malmerberg, L. Lomb, C. Caleman, J. Ullrich, A. Barty, S. Marchesini, R. A. Kirian, X. Wang, L. Foucar, B. Erk, J. Davidsson, G. n. Hauser, H. Graafsma, D. P. DePonte, N. Timneanu, M. Liang, R. Sierra, A. Hˆmke, I. Schlichting, F. R. N. C. Maia, G. Weidenspointner, C. Wunderer, T. R. M. Barends, L. Str¸der, R. Hartmann, H. Soltau, D. Starodub, L. Johansson, C. Bostedt, S. W. Epp, J. Schulz, A. Aquila, S. Kassemeyer, V. Elser, K.-U. K¸hnel, A. V. Martin, J. D. Bozek, G. J. Williams, H. Fleckenstein, D. Arnlund, M. J. Bogan, R. Neutze, N. Kimmel, I. Grotjohann, F. Krasniqi, C. Reich, T. A. White, A. Hartmann, R. B. Doak, D. Rolles, L. Gumprecht, B. Rudek, S. Stern, J. Hajdu, H. Hirsemann, P. Holl, M. M. Seibert, S. a. Bajt, K. Nass, A. Rudenko, J. Andreasson, F. Stellato, H. Bottin, C. Y. Hampton, M. Barthelmess, R. L. Shoeman, N. Coppola, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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