Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): A. V. Martin, K. Nass, G. J. Williams, J. Andreasson, D. Arnlund, H. Bottin, S. Kassemeyer, S. W. Epp, F. Krasniqi, M. J. Bogan, C. Reich, L. Lomb, R. Neutze, A. Hartmann, J. Ullrich, N. Kimmel, V. Elser, B. Rudek, L. Foucar, R. B. Doak, J. Davidsson, D. Rolles, H. Graafsma, T. A. White, P. Holl, F. Stellato, I. Schlichting, M. M. Seibert, C. Y. Hampton, G. Weidenspointner, S. a. Bajt, A. Rudenko, S. Stern, E. Malmerberg, H. Soltau, M. Barthelmess, C. Caleman, L. Johansson, R. L. Shoeman, A. Barty, J. Schulz, N. Coppola, B. Erk, K.-U. K¸hnel, R. A. Kirian, G. n. Hauser, J. D. Bozek, D. P. DePonte, H. Fleckenstein, S. Marchesini, F. R. N. C. Maia, I. Grotjohann, M. Liang, C. Wunderer, R. Sierra, A. Hˆmke, N. Timneanu, X. Wang, H. Hirsemann, L. Str¸der, C. Bostedt, L. Gumprecht, R. Hartmann, A. Aquila, J. Hajdu, D. Starodub, T. R. M. Barends, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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