Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): L. Str¸der, C. Y. Hampton, R. Hartmann, A. Rudenko, F. Stellato, J. Davidsson, S. Stern, H. Graafsma, L. Foucar, A. Barty, E. Malmerberg, S. Kassemeyer, C. Caleman, G. Weidenspointner, I. Schlichting, G. n. Hauser, M. J. Bogan, D. P. DePonte, R. Neutze, B. Erk, N. Kimmel, J. Schulz, H. Soltau, L. Johansson, C. Wunderer, R. B. Doak, A. Hˆmke, F. R. N. C. Maia, H. Fleckenstein, K.-U. K¸hnel, X. Wang, J. D. Bozek, P. Holl, A. Aquila, M. M. Seibert, D. Starodub, S. a. Bajt, C. Bostedt, T. R. M. Barends, I. Grotjohann, M. Barthelmess, D. Arnlund, R. L. Shoeman, A. V. Martin, N. Coppola, G. J. Williams, J. Hajdu, S. W. Epp, H. Hirsemann, L. Gumprecht, R. A. Kirian, A. Hartmann, F. Krasniqi, S. Marchesini, C. Reich, H. Bottin, K. Nass, V. Elser, J. Andreasson, M. Liang, D. Rolles, R. Sierra, B. Rudek, N. Timneanu, J. Ullrich, T. A. White, L. Lomb, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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