Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): S. W. Epp, M. Liang, A. Hartmann, J. Schulz, R. Sierra, F. Krasniqi, H. Soltau, N. Timneanu, C. Reich, L. Johansson, V. Elser, J. D. Bozek, R. Hartmann, D. Rolles, H. Fleckenstein, B. Rudek, K.-U. K¸hnel, L. Str¸der, T. A. White, A. Rudenko, S. Kassemeyer, F. Stellato, I. Grotjohann, C. Y. Hampton, S. Stern, J. Hajdu, R. Neutze, E. Malmerberg, H. Hirsemann, N. Kimmel, C. Caleman, L. Gumprecht, M. J. Bogan, A. Barty, R. B. Doak, D. P. DePonte, H. Bottin, B. Erk, K. Nass, G. n. Hauser, J. Andreasson, L. Lomb, M. M. Seibert, A. Hˆmke, J. Ullrich, S. a. Bajt, F. R. N. C. Maia, P. Holl, C. Wunderer, X. Wang, J. Davidsson, R. L. Shoeman, D. Starodub, H. Graafsma, N. Coppola, C. Bostedt, L. Foucar, M. Barthelmess, A. Aquila, T. R. M. Barends, D. Arnlund, G. Weidenspointner, A. V. Martin, S. Marchesini, G. J. Williams, I. Schlichting, R. A. Kirian, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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