Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): T. R. M. Barends, S. Kassemeyer, A. Aquila, D. Starodub, I. Grotjohann, C. Bostedt, S. W. Epp, G. J. Williams, N. Kimmel, J. Hajdu, D. Arnlund, M. J. Bogan, H. Hirsemann, A. V. Martin, R. Neutze, L. Gumprecht, V. Elser, C. Reich, H. Bottin, A. Hartmann, R. B. Doak, K. Nass, F. Krasniqi, J. Andreasson, T. A. White, L. Lomb, P. Holl, J. Ullrich, D. Rolles, M. M. Seibert, B. Rudek, S. a. Bajt, S. Stern, F. Stellato, N. Coppola, J. Davidsson, C. Y. Hampton, M. Barthelmess, H. Graafsma, A. Rudenko, R. L. Shoeman, L. Foucar, C. Caleman, S. Marchesini, G. Weidenspointner, A. Barty, R. A. Kirian, E. Malmerberg, I. Schlichting, G. n. Hauser, N. Timneanu, J. Schulz, D. P. DePonte, M. Liang, H. Soltau, B. Erk, R. Sierra, L. Johansson, X. Wang, J. D. Bozek, C. Wunderer, L. Str¸der, H. Fleckenstein, A. Hˆmke, R. Hartmann, K.-U. K¸hnel, F. R. N. C. Maia, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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