Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): J. D. Bozek, H. Fleckenstein, K.-U. K¸hnel, D. Starodub, C. Bostedt, S. Marchesini, A. Aquila, R. A. Kirian, X. Wang, I. Grotjohann, M. Liang, A. V. Martin, R. Sierra, G. J. Williams, N. Timneanu, D. Arnlund, T. R. M. Barends, J. Hajdu, H. Hirsemann, L. Gumprecht, R. Hartmann, F. Krasniqi, C. Reich, L. Str¸der, A. Hartmann, H. Bottin, K. Nass, S. W. Epp, J. Andreasson, B. Rudek, S. Kassemeyer, D. Rolles, L. Lomb, V. Elser, J. Ullrich, A. Rudenko, R. Neutze, F. Stellato, N. Kimmel, C. Y. Hampton, M. J. Bogan, J. Davidsson, H. Graafsma, L. Foucar, T. A. White, R. B. Doak, E. Malmerberg, C. Caleman, A. Barty, G. Weidenspointner, S. Stern, I. Schlichting, M. M. Seibert, B. Erk, S. a. Bajt, G. n. Hauser, P. Holl, D. P. DePonte, J. Schulz, H. Soltau, L. Johansson, R. L. Shoeman, F. R. N. C. Maia, N. Coppola, C. Wunderer, M. Barthelmess, A. Hˆmke, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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