Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): C. Caleman, H. Graafsma, A. Barty, L. Foucar, E. Malmerberg, J. Davidsson, R. B. Doak, G. n. Hauser, D. P. DePonte, I. Schlichting, B. Erk, G. Weidenspointner, M. M. Seibert, S. a. Bajt, P. Holl, F. R. N. C. Maia, J. Schulz, C. Wunderer, H. Soltau, A. Hˆmke, L. Johansson, R. L. Shoeman, N. Coppola, M. Barthelmess, X. Wang, C. Bostedt, H. Fleckenstein, A. Aquila, K.-U. K¸hnel, D. Starodub, J. D. Bozek, S. Marchesini, T. R. M. Barends, R. A. Kirian, G. J. Williams, D. Arnlund, I. Grotjohann, A. V. Martin, R. Sierra, S. W. Epp, N. Timneanu, M. Liang, C. Reich, H. Hirsemann, A. Hartmann, L. Gumprecht, F. Krasniqi, J. Hajdu, R. Hartmann, L. Str¸der, V. Elser, B. Rudek, H. Bottin, K. Nass, D. Rolles, J. Andreasson, S. Kassemeyer, T. A. White, F. Stellato, J. Ullrich, C. Y. Hampton, A. Rudenko, L. Lomb, R. Neutze, S. Stern, N. Kimmel, M. J. Bogan, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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