Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): M. Liang, R. Sierra, I. Schlichting, N. Timneanu, G. Weidenspointner, E. Malmerberg, C. Caleman, A. Barty, R. Hartmann, H. Soltau, L. Johansson, L. Str¸der, J. Schulz, B. Erk, G. n. Hauser, D. P. DePonte, H. Fleckenstein, K.-U. K¸hnel, X. Wang, S. Kassemeyer, J. D. Bozek, A. Hˆmke, F. R. N. C. Maia, C. Wunderer, T. R. M. Barends, R. Neutze, I. Grotjohann, N. Kimmel, M. J. Bogan, D. Starodub, C. Bostedt, A. Aquila, R. B. Doak, H. Hirsemann, L. Gumprecht, J. Hajdu, S. W. Epp, A. V. Martin, G. J. Williams, D. Arnlund, M. M. Seibert, K. Nass, V. Elser, S. a. Bajt, J. Andreasson, P. Holl, H. Bottin, F. Krasniqi, C. Reich, A. Hartmann, J. Ullrich, T. A. White, R. L. Shoeman, N. Coppola, L. Lomb, M. Barthelmess, D. Rolles, B. Rudek, H. Graafsma, L. Foucar, S. Marchesini, J. Davidsson, S. Stern, R. A. Kirian, A. Rudenko, F. Stellato, C. Y. Hampton, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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