Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): T. A. White, G. Weidenspointner, I. Schlichting, M. Barthelmess, D. Rolles, R. L. Shoeman, B. Rudek, N. Coppola, J. Schulz, H. Soltau, S. Stern, L. Johansson, S. Marchesini, C. Y. Hampton, R. A. Kirian, A. Rudenko, F. Stellato, J. D. Bozek, H. Fleckenstein, K.-U. K¸hnel, N. Timneanu, A. Barty, M. Liang, E. Malmerberg, R. Sierra, C. Caleman, I. Grotjohann, G. n. Hauser, L. Str¸der, D. P. DePonte, R. Hartmann, B. Erk, J. Hajdu, X. Wang, H. Hirsemann, L. Gumprecht, C. Wunderer, A. Hˆmke, F. R. N. C. Maia, S. Kassemeyer, T. R. M. Barends, H. Bottin, K. Nass, J. Andreasson, N. Kimmel, A. Aquila, M. J. Bogan, D. Starodub, R. Neutze, C. Bostedt, S. W. Epp, L. Lomb, J. Ullrich, D. Arnlund, R. B. Doak, A. V. Martin, G. J. Williams, J. Davidsson, V. Elser, H. Graafsma, L. Foucar, C. Reich, P. Holl, A. Hartmann, M. M. Seibert, F. Krasniqi, S. a. Bajt, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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