Time-resolved protein nanocrystallography using an X-ray free-electron laser
29 Jan 2012 | Publications | Contributor(s): L. Gumprecht, S. W. Epp, J. Hajdu, H. Hirsemann, S. Kassemeyer, A. Hartmann, F. Krasniqi, C. Reich, J. Andreasson, H. Bottin, V. Elser, K. Nass, N. Kimmel, D. Rolles, M. J. Bogan, B. Rudek, R. Neutze, L. Lomb, T. A. White, J. Ullrich, C. Y. Hampton, A. Rudenko, R. B. Doak, F. Stellato, L. Foucar, S. Stern, J. Davidsson, H. Graafsma, S. a. Bajt, A. Barty, P. Holl, E. Malmerberg, M. M. Seibert, C. Caleman, I. Schlichting, G. Weidenspointner, N. Coppola, D. P. DePonte, M. Barthelmess, B. Erk, R. L. Shoeman, G. n. Hauser, L. Johansson, J. Schulz, H. Soltau, C. Wunderer, S. Marchesini, A. Hˆmke, R. A. Kirian, F. R. N. C. Maia, K.-U. K¸hnel, J. D. Bozek, H. Fleckenstein, X. Wang, R. Sierra, A. Aquila, N. Timneanu, D. Starodub, M. Liang, C. Bostedt, I. Grotjohann, T. R. M. Barends, D. Arnlund, L. Str¸der, A. V. Martin, R. Hartmann, G. J. Williams, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
We demonstrate the use of an X-ray free electron laser synchronized with an optical pump laser to obtain X-ray diffraction snapshots from the photoactivated states of large membrane protein complexes …
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