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Chromatin-remodeling and the initiation of transcription

By Yahli Lorch, Roger Kornberg1

1. Stanford University

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Category

BioXFEL Publications

Published on

Type

journal-article

Author

Yahli Lorch and Roger D. Kornberg

Citation

Lorch, Y. & Kornberg, R.D., 2015. Chromatin-remodeling and the initiation of transcription. Quarterly Reviews of Biophysics, 48(04), pp.465–470. Available at: http://dx.doi.org/10.1017/s0033583515000116.

Abstract

AbstractThe nucleosome serves as a general gene repressor by the occlusion of regulatory and promoter DNA sequences. Repression is relieved by the SWI/SNF-RSC family of chromatin-remodeling complexes. Research reviewed here has revealed the essential features of the remodeling process.

DOI

http://dx.doi.org/10.1017/s0033583515000116