The lipid phase preference of the adenosine A2A receptor depends on its ligand binding state
Category
Published on
Type
journal-article
Author
M. Gertrude Gutierrez and Jacob Deyell and Kate L. White and Lucia C. Dalle Ore and Vadim Cherezov and Raymond C. Stevens and Noah Malmstadt
Citation
Gutierrez, M.G. et al., 2019. The lipid phase preference of the adenosine A2A receptor depends on its ligand binding state. Chemical Communications, 55(40), pp.5724–5727. Available at: http://dx.doi.org/10.1039/c8cc10130b.
Abstract
As cholesterol fraction increases, ligand-bound receptor occupies more vesicle surface area, demonstrating co-localization with the cholesterol-rich phase.