XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity

By Linda C. Johansson, Benjamin Stauch1, John D. McCorvy, Gye Won Han, Nilkanth N Patel1, Xi-Ping Huang, Alexander Batyuk, Cornelius Gati, Samuel T. Slocum, Chufeng Li2, Jessica M. Grandner, Shuming Hao, Reid H. J. Olsen, Alexandra R. Tribo, Sahba Zaare, Lan Zhu2, Nadia Zatsepin2, Uwe Weierstall2, Saïd Yous, Raymond C. Stevens, Wei Liu2, Bryan L. Roth, Vsevolod Katritch, Vadim Cherezov3

1. University of Southern California 2. Arizona State University 3. Bridge Institute - University of Southern California

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Type

journal-article

Author

Linda C. Johansson and Benjamin Stauch and John D. McCorvy and Gye Won Han and Nilkanth Patel and Xi-Ping Huang and Alexander Batyuk and Cornelius Gati and Samuel T. Slocum and Chufeng Li and Jessica M. Grandner and Shuming Hao and Reid H. J. Olsen and Alexandra R. Tribo and Sahba Zaare and Lan Zhu and Nadia A. Zatsepin and Uwe Weierstall and Saïd Yous and Raymond C. Stevens and Wei Liu and Bryan L. Roth and Vsevolod Katritch and Vadim Cherezov

Citation

Johansson, L.C. et al., 2019. XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity. Nature. Available at: http://dx.doi.org/10.1038/s41586-019-1144-0.

DOI

Funding

NSF-STC Biology with X-ray Lasers (NSF-1231306)