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A National Science Foundation Science and Technology Center

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Crystal Cryocooling Distorts Conformational Heterogeneity in a Model Michaelis Complex of DHFR

By Daniel A. Keedy, Henry Van den Bedem, David A. Sivak, Gregory A. Petsko, Dagmar Ringe¹, Mark A. Wilson, James S. Fraser

1. Brandeis University

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