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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): R. L. Shoeman, L. Foucar, S. Boutet, I. Schlichting, R. B. Doak, K. Nass, S. Botha, G. J. Williams, T. R. Barends, J. E. Koglin, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://www.bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): G. W. Han, A. Barty, K. R. Beyerlein, S. Boutet, D. Wacker, M. M. Seibert, C. Gati, T. A. White, G. J. Williams, K. N. Rendek, S. Basu, N. A. Zatsepin, J. E. Koglin, V. Katritch, M. Caffrey, S. T. Shah, D. Wang, R. A. Kirian, W. Liu, R. C. Stevens, I. Grotjohann, C. Wang, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://www.bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): M. Bott, R. Andritschke, A. Barty, G. J. Williams, T. R. Barends, D. Rupp, J. Schulz, S. Herrmann, C. Bostedt, L. Struder, P. Holl, D. P. DePonte, J. D. Bozek, R. Neutze, B. Erk, H. Graafsma, G. Hauser, K. U. Kuhnel, N. Kimmel, M. Liang, A. Rocker, G. Schaller, X. Wang, F. Krasniqi, S. Schorb, C. D. Schroter, I. Grotjohann, R. G. Sierra, M. Barthelmess, R. A. Kirian, T. Gorkhover, D. Rolles, J. Krzywinski, S. Boutet, B. Rudek, H. Soltau, A. Aquila, L. Lomb, O. Jonsson, M. Svenda, C. Y. Hampton, J. Andreasson, R. L. Shoeman, A. V. Martin, H. Gorke, F. Schopper, K. Nass, S. W. Epp, N. Coppola, M. J. Bogan, R. B. Doak, A. Homke, G. Potdevin, D. Starodub, J. Ullrich, S. Marchesini, C. Caleman, I. Andersson, M. Adolph, D. Pietschner, J. Hajdu, S. Bajt, B. Nilsson, H. Hirsemann, L. Foucar, T. A. White, L. Gumprecht, N. Timneanu, M. M. Seibert, I. Schlichting, R. Hartmann, A. Rudenko, G. Weidenspointner, F. R. Maia, S. Stern, C. Reich, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://www.bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): B. Iwan, S. Bajt, A. A. Miahnahri, M. Adolph, C. Y. Hampton, T. A. White, H. Graafsma, F. R. Maia, J. Hajdu, R. Hartmann, D. Rupp, L. Gumprecht, C. Caleman, N. Kimmel, S. Stern, A. Rocker, M. Liang, I. Schlichting, G. Weidenspointner, D. P. DePonte, K. O. Hodgson, T. Gorkhover, B. Rudek, S. Herrmann, A. Barty, M. Bott, R. Andritschke, J. M. Claverie, H. Soltau, G. Hauser, B. Erk, M. Svenda, R. L. Shoeman, L. Struder, C. Reich, P. Holl, H. Gorke, F. Krasniqi, J. D. Bozek, D. Rolles, L. Foucar, V. Seltzer, C. Bostedt, N. Coppola, S. Schorb, A. Martin, M. J. Bogan, R. G. Sierra, J. Ullrich, I. Andersson, G. Schaller, T. Ekeberg, B. Nilsson, S. Boutet, A. Aquila, M. Barthelmess, D. Odic, H. Hirsemann, F. Schopper, J. Krzywinski, A. Rudenko, M. M. Seibert, R. Kirian, D. Starodub, L. Lomb, C. D. Schroter, O. Jonsson, S. W. Epp, G. Williams, D. Westphal, J. Andreasson, D. Pietschner, K. U. Kuhnel, C. Abergel, S. Marchesini, A. Homke, M. Hantke, R. B. Doak, J. Schulz, G. Potdevin, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://www.bioxfel.org/resources/294
