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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): R. B. Doak, K. Nass, S. Botha, G. J. Williams, T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, S. Boutet, I. Schlichting, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://www.bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): C. Gati, M. M. Seibert, G. J. Williams, S. Boutet, K. N. Rendek, N. A. Zatsepin, J. E. Koglin, T. A. White, M. Caffrey, R. A. Kirian, S. Basu, D. Wang, I. Grotjohann, C. Wang, V. Katritch, G. W. Han, A. Barty, S. T. Shah, K. R. Beyerlein, R. C. Stevens, D. Wacker, W. Liu, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://www.bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): B. Erk, G. Hauser, S. Marchesini, D. P. DePonte, G. J. Williams, M. Adolph, J. Schulz, T. A. White, F. Krasniqi, S. Bajt, C. D. Schroter, A. Rocker, K. U. Kuhnel, L. Gumprecht, J. D. Bozek, N. Timneanu, H. Graafsma, M. M. Seibert, R. Hartmann, B. Rudek, A. Aquila, S. Stern, D. Rolles, R. Andritschke, I. Grotjohann, G. Schaller, M. Bott, A. V. Martin, T. R. Barends, F. Schopper, S. Herrmann, C. Y. Hampton, H. Soltau, L. Struder, J. Krzywinski, P. Holl, D. Starodub, R. Neutze, C. Caleman, A. Homke, K. Nass, J. Andreasson, N. Kimmel, H. Gorke, M. Liang, R. G. Sierra, B. Nilsson, X. Wang, S. Schorb, D. Pietschner, I. Andersson, G. Potdevin, M. Barthelmess, J. Ullrich, R. A. Kirian, T. Gorkhover, F. R. Maia, S. Boutet, C. Reich, A. Rudenko, L. Foucar, L. Lomb, J. Hajdu, O. Jonsson, H. Hirsemann, M. Svenda, S. W. Epp, D. Rupp, R. L. Shoeman, C. Bostedt, A. Barty, R. B. Doak, I. Schlichting, N. Coppola, G. Weidenspointner, M. J. Bogan, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://www.bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): R. Kirian, M. Adolph, S. W. Epp, J. Schulz, B. Rudek, A. Barty, G. Potdevin, D. P. DePonte, L. Gumprecht, N. Kimmel, S. Marchesini, M. Liang, R. B. Doak, B. Erk, H. Graafsma, F. R. Maia, C. Reich, J. Hajdu, S. Bajt, M. Bott, K. O. Hodgson, T. A. White, D. Rolles, C. Bostedt, I. Schlichting, A. Martin, G. Weidenspointner, R. Hartmann, L. Struder, P. Holl, S. Stern, M. Svenda, B. Nilsson, H. Soltau, A. Aquila, G. Hauser, D. Odic, J. M. Claverie, T. Gorkhover, N. Coppola, S. Herrmann, M. J. Bogan, R. Andritschke, L. Foucar, H. Gorke, D. Starodub, F. Krasniqi, C. D. Schroter, J. D. Bozek, A. Rudenko, R. L. Shoeman, M. Barthelmess, D. Pietschner, J. Ullrich, C. Abergel, I. Andersson, A. Homke, G. Schaller, L. Lomb, V. Seltzer, O. Jonsson, S. Schorb, M. M. Seibert, R. G. Sierra, B. Iwan, H. Hirsemann, A. A. Miahnahri, F. Schopper, C. Y. Hampton, J. Krzywinski, T. Ekeberg, S. Boutet, M. Hantke, K. U. Kuhnel, D. Rupp, D. Westphal, C. Caleman, J. Andreasson, A. Rocker, G. Williams, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://www.bioxfel.org/resources/294
