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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): R. B. Doak, K. Nass, S. Botha, G. J. Williams, T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, S. Boutet, I. Schlichting, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://www.bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): G. J. Williams, S. Boutet, K. N. Rendek, N. A. Zatsepin, J. E. Koglin, T. A. White, M. Caffrey, D. Wang, S. Basu, R. A. Kirian, I. Grotjohann, V. Katritch, C. Wang, G. W. Han, S. T. Shah, A. Barty, K. R. Beyerlein, R. C. Stevens, W. Liu, D. Wacker, M. M. Seibert, C. Gati, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://www.bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): R. B. Doak, I. Grotjohann, B. Nilsson, T. R. Barends, N. Coppola, G. Schaller, S. Herrmann, M. J. Bogan, D. Pietschner, F. R. Maia, R. Neutze, M. Adolph, J. Krzywinski, C. Reich, H. Soltau, A. Rudenko, R. G. Sierra, L. Gumprecht, J. Andreasson, C. Bostedt, X. Wang, N. Timneanu, H. Gorke, A. Barty, S. Schorb, M. M. Seibert, K. Nass, D. Rupp, B. Erk, T. Gorkhover, G. Potdevin, G. Hauser, S. Boutet, M. Bott, J. Ullrich, D. P. DePonte, R. Andritschke, I. Andersson, L. Foucar, F. Krasniqi, R. L. Shoeman, L. Struder, J. Hajdu, C. D. Schroter, P. Holl, H. Hirsemann, A. Rocker, S. W. Epp, I. Schlichting, B. Rudek, N. Kimmel, G. Weidenspointner, A. Aquila, S. Marchesini, M. Liang, D. Rolles, T. A. White, G. J. Williams, F. Schopper, S. Bajt, M. Barthelmess, J. Schulz, C. Y. Hampton, R. A. Kirian, A. V. Martin, D. Starodub, R. Hartmann, L. Lomb, J. D. Bozek, C. Caleman, O. Jonsson, H. Graafsma, A. Homke, S. Stern, M. Svenda, K. U. Kuhnel, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://www.bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): P. Holl, H. Graafsma, B. Erk, M. Svenda, F. R. Maia, R. L. Shoeman, L. Struder, J. Hajdu, C. Reich, S. Schorb, M. J. Bogan, D. Rolles, R. G. Sierra, L. Foucar, I. Schlichting, C. Bostedt, V. Seltzer, N. Coppola, G. Weidenspointner, A. Martin, H. Soltau, B. Nilsson, T. Ekeberg, G. Hauser, A. Aquila, S. Boutet, M. Barthelmess, J. M. Claverie, D. Odic, A. Rudenko, S. W. Epp, M. M. Seibert, F. Krasniqi, D. Starodub, R. Kirian, L. Lomb, J. D. Bozek, C. D. Schroter, O. Jonsson, H. Gorke, J. Ullrich, D. Pietschner, R. B. Doak, K. U. Kuhnel, I. Andersson, C. Abergel, G. Schaller, A. Homke, S. Marchesini, M. Hantke, H. Hirsemann, B. Iwan, T. A. White, F. Schopper, A. A. Miahnahri, S. Bajt, M. Adolph, J. Krzywinski, C. Y. Hampton, S. Stern, M. Liang, D. Westphal, D. Rupp, R. Hartmann, L. Gumprecht, J. Andreasson, C. Caleman, N. Kimmel, G. Williams, A. Rocker, D. P. DePonte, R. Andritschke, K. O. Hodgson, B. Rudek, T. Gorkhover, G. Potdevin, A. Barty, S. Herrmann, M. Bott, J. Schulz, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://www.bioxfel.org/resources/294
