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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): J. E. Koglin, T. R. Barends, R. L. Shoeman, L. Foucar, I. Schlichting, S. Boutet, R. B. Doak, K. Nass, G. J. Williams, S. Botha, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://www.bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): D. Wacker, S. Boutet, C. Gati, M. M. Seibert, K. N. Rendek, G. J. Williams, T. A. White, J. E. Koglin, N. A. Zatsepin, S. Basu, V. Katritch, M. Caffrey, D. Wang, R. A. Kirian, S. T. Shah, C. Wang, W. Liu, R. C. Stevens, I. Grotjohann, A. Barty, K. R. Beyerlein, G. W. Han, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://www.bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): C. Y. Hampton, A. V. Martin, I. Grotjohann, F. Schopper, G. Schaller, M. Liang, T. R. Barends, S. Herrmann, N. Kimmel, A. Homke, H. Soltau, D. Starodub, C. Caleman, J. Krzywinski, R. Neutze, R. A. Kirian, M. Barthelmess, D. Pietschner, K. Nass, B. Nilsson, J. Andreasson, H. Gorke, M. Svenda, X. Wang, L. Lomb, S. Schorb, R. G. Sierra, O. Jonsson, C. Reich, J. Ullrich, A. Rudenko, I. Andersson, F. R. Maia, G. Potdevin, M. J. Bogan, T. Gorkhover, S. Boutet, R. B. Doak, N. Coppola, A. Barty, H. Hirsemann, D. Rupp, L. Foucar, C. Bostedt, J. Hajdu, R. L. Shoeman, M. Adolph, S. W. Epp, D. P. DePonte, B. Erk, I. Schlichting, G. Hauser, G. Weidenspointner, M. M. Seibert, L. Gumprecht, S. Marchesini, N. Timneanu, J. Schulz, A. Rocker, F. Krasniqi, G. J. Williams, C. D. Schroter, S. Bajt, R. Andritschke, M. Bott, T. A. White, A. Aquila, H. Graafsma, D. Rolles, K. U. Kuhnel, B. Rudek, J. D. Bozek, R. Hartmann, P. Holl, L. Struder, S. Stern, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://www.bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): C. Caleman, J. Hajdu, A. Rocker, H. Graafsma, D. Rupp, F. R. Maia, M. Adolph, R. L. Shoeman, A. Barty, G. Weidenspointner, D. P. DePonte, B. Rudek, I. Schlichting, R. G. Sierra, N. Kimmel, M. Liang, V. Seltzer, L. Gumprecht, S. Schorb, C. Reich, J. M. Claverie, B. Erk, H. Soltau, G. Hauser, M. Bott, T. Ekeberg, K. O. Hodgson, S. Boutet, C. Bostedt, J. D. Bozek, A. Martin, H. Gorke, D. Rolles, F. Krasniqi, L. Struder, S. W. Epp, R. Kirian, P. Holl, M. Svenda, A. Aquila, G. Schaller, D. Odic, J. Ullrich, B. Nilsson, I. Andersson, R. B. Doak, N. Coppola, M. J. Bogan, L. Foucar, S. Marchesini, C. D. Schroter, J. Krzywinski, A. Rudenko, H. Hirsemann, D. Starodub, F. Schopper, M. Barthelmess, T. A. White, S. Bajt, J. Andreasson, A. Homke, G. Williams, D. Pietschner, D. Westphal, C. Abergel, R. Hartmann, O. Jonsson, M. M. Seibert, L. Lomb, S. Stern, A. A. Miahnahri, G. Potdevin, C. Y. Hampton, J. Schulz, B. Iwan, R. Andritschke, M. Hantke, T. Gorkhover, K. U. Kuhnel, S. Herrmann, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://www.bioxfel.org/resources/294
