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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): R. B. Doak, K. Nass, G. J. Williams, S. Botha, T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, I. Schlichting, S. Boutet, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://www.bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): R. A. Kirian, D. Wang, V. Katritch, I. Grotjohann, C. Wang, S. T. Shah, W. Liu, A. Barty, R. C. Stevens, K. R. Beyerlein, G. W. Han, D. Wacker, C. Gati, S. Boutet, M. M. Seibert, K. N. Rendek, G. J. Williams, J. E. Koglin, T. A. White, N. A. Zatsepin, S. Basu, M. Caffrey, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://www.bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): G. Hauser, L. Foucar, T. A. White, D. P. DePonte, J. Hajdu, S. Bajt, N. Kimmel, B. Erk, H. Hirsemann, M. Liang, S. Stern, R. A. Kirian, C. D. Schroter, I. Schlichting, R. Hartmann, A. Rocker, G. Weidenspointner, M. Barthelmess, F. Krasniqi, M. Svenda, A. Aquila, G. J. Williams, T. R. Barends, L. Lomb, D. Rolles, J. Schulz, S. Herrmann, O. Jonsson, B. Rudek, K. U. Kuhnel, R. B. Doak, C. Y. Hampton, J. D. Bozek, R. Neutze, N. Coppola, A. V. Martin, H. Graafsma, M. J. Bogan, F. Schopper, C. Caleman, I. Grotjohann, R. G. Sierra, A. Homke, G. Schaller, X. Wang, M. Adolph, D. Starodub, S. Schorb, M. M. Seibert, T. Gorkhover, L. Gumprecht, D. Pietschner, J. Krzywinski, S. Boutet, N. Timneanu, B. Nilsson, H. Soltau, K. Nass, S. W. Epp, R. Andritschke, C. Reich, J. Andreasson, R. L. Shoeman, A. Rudenko, H. Gorke, M. Bott, F. R. Maia, I. Andersson, A. Barty, G. Potdevin, L. Struder, D. Rupp, J. Ullrich, S. Marchesini, P. Holl, C. Bostedt, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://www.bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): D. Starodub, J. Ullrich, S. Stern, C. D. Schroter, I. Andersson, R. Hartmann, A. Rudenko, G. Schaller, M. Adolph, S. Herrmann, N. Kimmel, C. Abergel, H. Hirsemann, R. Andritschke, M. Liang, A. Homke, F. Schopper, T. Gorkhover, L. Gumprecht, D. Pietschner, J. Krzywinski, G. Williams, M. Bott, A. A. Miahnahri, D. Westphal, K. O. Hodgson, C. Y. Hampton, J. Andreasson, R. L. Shoeman, B. Iwan, J. Schulz, S. Schorb, P. Holl, C. Caleman, R. G. Sierra, M. Svenda, A. Rocker, G. Potdevin, V. Seltzer, L. Struder, D. Rupp, B. Rudek, H. Graafsma, M. J. Bogan, A. Barty, F. R. Maia, T. Ekeberg, L. Foucar, D. P. DePonte, J. Hajdu, S. Boutet, N. Coppola, M. Barthelmess, S. W. Epp, C. Reich, I. Schlichting, R. Kirian, B. Erk, G. Weidenspointner, J. M. Claverie, S. Marchesini, O. Jonsson, C. Bostedt, H. Soltau, R. B. Doak, M. M. Seibert, A. Martin, G. Hauser, L. Lomb, D. Rolles, H. Gorke, M. Hantke, A. Aquila, F. Krasniqi, T. A. White, K. U. Kuhnel, D. Odic, J. D. Bozek, S. Bajt, B. Nilsson, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://www.bioxfel.org/resources/294
