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De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): R. B. Doak, K. Nass, S. Botha, G. J. Williams, T. R. Barends, J. E. Koglin, R. L. Shoeman, L. Foucar, S. Boutet, I. Schlichting, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://www.bioxfel.org/resources/238
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Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): D. Wang, R. A. Kirian, T. A. White, C. Wang, I. Grotjohann, S. Basu, K. R. Beyerlein, G. W. Han, A. Barty, V. Katritch, D. Wacker, S. T. Shah, M. M. Seibert, C. Gati, W. Liu, R. C. Stevens, K. N. Rendek, G. J. Williams, N. A. Zatsepin, J. E. Koglin, S. Boutet, M. Caffrey, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://www.bioxfel.org/resources/290
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Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): O. Jonsson, M. Svenda, J. Krzywinski, L. Lomb, H. Soltau, B. Erk, T. R. Barends, G. Hauser, S. Herrmann, D. P. DePonte, K. Nass, M. J. Bogan, J. Andreasson, R. B. Doak, H. Gorke, N. Coppola, A. Rocker, F. Krasniqi, R. Neutze, C. D. Schroter, M. Adolph, I. Andersson, G. Potdevin, J. Ullrich, S. Schorb, D. Rolles, R. G. Sierra, B. Rudek, X. Wang, A. Aquila, N. Timneanu, L. Foucar, M. M. Seibert, J. Hajdu, L. Gumprecht, H. Hirsemann, A. V. Martin, T. Gorkhover, F. Schopper, S. Boutet, C. Y. Hampton, M. Bott, I. Schlichting, R. Andritschke, G. Weidenspointner, S. W. Epp, D. Starodub, R. L. Shoeman, C. Caleman, A. Homke, P. Holl, G. J. Williams, J. Schulz, L. Struder, S. Marchesini, D. Pietschner, B. Nilsson, N. Kimmel, K. U. Kuhnel, M. Liang, J. D. Bozek, H. Graafsma, A. Rudenko, T. A. White, F. R. Maia, S. Bajt, C. Reich, M. Barthelmess, I. Grotjohann, R. A. Kirian, G. Schaller, S. Stern, D. Rupp, R. Hartmann, C. Bostedt, A. Barty, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://www.bioxfel.org/resources/252
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Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): M. Bott, I. Schlichting, K. O. Hodgson, G. Weidenspointner, A. Rudenko, D. Starodub, R. L. Shoeman, C. D. Schroter, J. M. Claverie, L. Struder, H. Soltau, P. Holl, G. Hauser, M. Svenda, V. Seltzer, A. Homke, S. Schorb, D. Pietschner, R. G. Sierra, C. Abergel, L. Foucar, H. Gorke, N. Coppola, F. Krasniqi, M. J. Bogan, J. D. Bozek, S. Boutet, C. Y. Hampton, B. Iwan, T. Ekeberg, A. A. Miahnahri, J. Ullrich, M. Barthelmess, I. Andersson, G. Schaller, A. Rocker, S. W. Epp, D. Rupp, R. Kirian, C. Caleman, L. Lomb, H. Hirsemann, O. Jonsson, F. Schopper, M. M. Seibert, J. Krzywinski, S. Marchesini, D. P. DePonte, R. B. Doak, B. Rudek, A. Barty, G. Williams, D. Westphal, M. Hantke, J. Andreasson, K. U. Kuhnel, S. Bajt, C. Reich, B. Erk, T. A. White, J. Schulz, M. Adolph, G. Potdevin, A. Martin, S. Stern, D. Rolles, R. Hartmann, C. Bostedt, L. Gumprecht, H. Graafsma, N. Kimmel, F. R. Maia, M. Liang, J. Hajdu, S. Herrmann, D. Odic, R. Andritschke, B. Nilsson, T. Gorkhover, A. Aquila, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://www.bioxfel.org/resources/294