-
De novo protein crystal structure determination from X-ray free-electron laser data
08 Jan 2014 | Publications | Contributor(s): L. Foucar, S. Boutet, I. Schlichting, R. B. Doak, K. Nass, S. Botha, G. J. Williams, T. R. Barends, J. E. Koglin, R. L. Shoeman, Mark Messerschmidt
The determination of protein crystal structures is hampered by the need for macroscopic crystals. X-ray free-electron lasers (FELs) provide extremely intense pulses of femtosecond duration, which …
https://www.bioxfel.org/resources/238
-
Serial femtosecond crystallography of G protein-coupled receptors
19 Dec 2013 | Publications | Contributor(s): N. A. Zatsepin, J. E. Koglin, V. Katritch, S. T. Shah, M. Caffrey, W. Liu, R. A. Kirian, R. C. Stevens, D. Wang, I. Grotjohann, C. Wang, G. W. Han, A. Barty, S. Boutet, K. R. Beyerlein, D. Wacker, C. Gati, T. A. White, M. M. Seibert, S. Basu, K. N. Rendek, G. J. Williams, Henry Chapman, Vadim Cherezov, Petra Fromme, James Holton, Christopher Kupitz, Applications Manager, Mark Messerschmidt, Garrett Charles Nelson, John Spence, Uwe Weierstall
X-ray crystallography of G protein-coupled receptors and other membrane proteins is hampered by difficulties associated with growing sufficiently large crystals that withstand radiation damage and …
https://www.bioxfel.org/resources/290
-
Femtosecond X-ray protein nanocrystallography
02 Feb 2011 | Publications | Contributor(s): M. J. Bogan, R. B. Doak, N. Coppola, F. R. Maia, S. Marchesini, L. Foucar, C. Reich, J. Hajdu, A. Rudenko, H. Hirsemann, M. Adolph, C. Bostedt, I. Schlichting, A. Barty, T. A. White, G. Weidenspointner, D. Rupp, S. Bajt, M. M. Seibert, L. Gumprecht, N. Timneanu, G. Hauser, S. Stern, G. J. Williams, D. P. DePonte, R. Hartmann, J. Schulz, B. Erk, M. Bott, R. Andritschke, S. Herrmann, K. U. Kuhnel, C. D. Schroter, J. D. Bozek, A. Rocker, T. R. Barends, H. Graafsma, F. Krasniqi, P. Holl, L. Struder, B. Rudek, I. Grotjohann, A. Aquila, G. Schaller, D. Rolles, R. Neutze, M. Liang, N. Kimmel, F. Schopper, S. Schorb, C. Y. Hampton, R. G. Sierra, J. Krzywinski, A. V. Martin, X. Wang, H. Soltau, R. A. Kirian, M. Barthelmess, K. Nass, C. Caleman, J. Andreasson, A. Homke, T. Gorkhover, H. Gorke, D. Starodub, S. Boutet, O. Jonsson, M. Svenda, L. Lomb, I. Andersson, S. W. Epp, G. Potdevin, D. Pietschner, R. L. Shoeman, J. Ullrich, B. Nilsson, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, James Holton, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray crystallography provides the vast majority of macromolecular structures, but the success of the method relies on growing crystals of sufficient size. In conventional measurements, the …
https://www.bioxfel.org/resources/252
-
Single mimivirus particles intercepted and imaged with an X-ray laser
02 Feb 2011 | Publications | Contributor(s): L. Struder, P. Holl, M. Svenda, D. Rolles, S. Bajt, J. Ullrich, C. Bostedt, I. Andersson, A. Martin, T. A. White, G. Schaller, N. Coppola, M. J. Bogan, L. Foucar, B. Nilsson, H. Hirsemann, A. Aquila, S. Stern, F. Schopper, D. Odic, R. Hartmann, J. Krzywinski, M. Barthelmess, G. Williams, D. Starodub, S. Herrmann, D. Westphal, C. D. Schroter, R. Andritschke, J. Andreasson, A. Rudenko, T. Gorkhover, L. Lomb, O. Jonsson, M. M. Seibert, R. L. Shoeman, J. Schulz, C. Abergel, A. Homke, G. Potdevin, D. Pietschner, M. Hantke, K. U. Kuhnel, B. Iwan, V. Seltzer, H. Graafsma, A. A. Miahnahri, S. Schorb, F. R. Maia, C. Y. Hampton, R. G. Sierra, J. Hajdu, M. Adolph, D. Rupp, S. Boutet, C. Caleman, I. Schlichting, A. Rocker, T. Ekeberg, G. Weidenspointner, N. Kimmel, M. Liang, L. Gumprecht, J. M. Claverie, B. Rudek, H. Soltau, A. Barty, S. W. Epp, G. Hauser, D. P. DePonte, R. Kirian, M. Bott, K. O. Hodgson, H. Gorke, S. Marchesini, F. Krasniqi, C. Reich, R. B. Doak, J. D. Bozek, B. Erk, Henry Chapman, Matthias Frank, Petra Fromme, Stefan Hau-Riege, Mark S. Hunter, Mark Messerschmidt, Marius Schmidt, John Spence, Uwe Weierstall
X-ray lasers offer new capabilities in understanding the structure of biological systems, complex materials and matter under extreme conditions. Very short and extremely bright, coherent X-ray …
https://www.bioxfel.org/resources/294