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GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A2A Adenosine Receptor BioXFEL Publications |
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17 Aug 2022 |
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Structural basis for receptor selectivity and inverse agonism in S1P5 receptors BioXFEL Publications |
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12 Aug 2022 |
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The ligand-bound state of a G protein-coupled receptor stabilizes the interaction of functional cholesterol molecules BioXFEL Publications |
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26 Feb 2021 |
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Sodium Binding in Cysteinyl Leukotriene G Protein-Coupled Receptors BioXFEL Publications |
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12 Feb 2021 |
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Harnessing the power of an X-ray laser for serial crystallography of membrane proteins crystallized in lipidic cubic phase BioXFEL Publications |
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15 Oct 2020 |
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XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia BioXFEL Publications |
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09 Mar 2020 |
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Virtual discovery of melatonin receptor ligands to modulate circadian rhythms BioXFEL Publications |
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10 Feb 2020 |
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Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors BioXFEL Publications |
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06 Dec 2019 |
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Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists BioXFEL Publications |
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28 Nov 2019 |
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Structural Insights into Melatonin Receptors BioXFEL Publications |
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06 Nov 2019 |
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Toward G protein-coupled receptor structure-based drug design using X-ray lasers BioXFEL Publications |
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24 Oct 2019 |
12 |
Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs BioXFEL Publications |
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09 Oct 2019 |
13 |
Publisher Correction: Structural basis of ligand recognition at the human MT1 melatonin receptor BioXFEL Publications |
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02 May 2019 |
14 |
The lipid phase preference of the adenosine A2A receptor depends on its ligand binding state BioXFEL Publications |
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30 Apr 2019 |
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XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity BioXFEL Publications |
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24 Apr 2019 |
16 |
Structural basis of ligand recognition at the human MT1 melatonin receptor BioXFEL Publications |
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24 Apr 2019 |
17 |
High-viscosity injector-based pink-beam serial crystallography of microcrystals at a synchrotron radiation source BioXFEL Publications |
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04 Apr 2019 |
18 |
Advances in Structure Determination of G Protein-Coupled Receptors by SFX BioXFEL Publications |
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27 Dec 2018 |
19 |
Crystal structure of misoprostol bound to the labor inducer prostaglandin E2 receptor BioXFEL Publications |
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29 Nov 2018 |
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Computational design of thermostabilizing point mutations for G protein-coupled receptors BioXFEL Publications |
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21 Jun 2018 |
21 |
Structural biology of G protein-coupled receptors: new opportunities from XFELs and cryoEM BioXFEL Publications |
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16 Mar 2018 |
22 |
Serial Femtosecond Crystallography of G Protein–Coupled Receptors BioXFEL Publications |
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15 Mar 2018 |
23 |
Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor BioXFEL Publications |
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04 Jan 2018 |
24 |
High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions BioXFEL Publications |
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04 Jan 2018 |
25 |
Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors BioXFEL Publications |
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27 Jul 2017 |
26 |
A Bright Future for Serial Femtosecond Crystallography with XFELs BioXFEL Publications |
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18 Jul 2017 |
27 |
Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody BioXFEL Publications |
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18 Jul 2017 |
28 |
Critical Role of Water Molecules in Proton Translocation by the Membrane-Bound Transhydrogenase BioXFEL Publications |
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22 Jun 2017 |
29 |
Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV BioXFEL Publications |
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21 Jun 2017 |
30 |
Crystallization of Membrane Proteins: An Overview BioXFEL Publications |
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01 Jun 2017 |
31 |
Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation BioXFEL Publications |
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24 May 2017 |
32 |
Structure of the full-length glucagon class B G-protein-coupled receptor BioXFEL Publications |
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17 May 2017 |
33 |
Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand BioXFEL Publications |
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17 May 2017 |
34 |
Chemically Stable Lipids for Membrane Protein Crystallization BioXFEL Publications |
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12 May 2017 |
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Structural basis for selectivity and diversity in angiotensin II receptors BioXFEL Publications |
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04 Apr 2017 |
36 |
Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists BioXFEL Publications |
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06 Dec 2016 |
37 |
Native phasing of x-ray free-electron laser data for a G protein-coupled receptor BioXFEL Publications |
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24 Sep 2016 |
38 |
Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography BioXFEL Publications |
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21 Sep 2016 |
39 |
Serial Femtosecond Crystallography of Membrane Proteins BioXFEL Publications |
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23 Aug 2016 |
40 |
Serial femtosecond crystallography datasets from G protein-coupled receptors BioXFEL Publications |
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29 Jul 2016 |
41 |
X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex BioXFEL Publications |
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11 Apr 2016 |
42 |
Structural Studies of the Human Kappa Opioid Receptor Active State Conformations BioXFEL Publications |
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16 Feb 2016 |
43 |
Preparation and Delivery of Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography BioXFEL Publications |
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16 Feb 2016 |
44 |
Ternary structure reveals mechanism of a membrane diacylglycerol kinase BioXFEL Publications |
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17 Dec 2015 |
45 |
The Fragment Molecular Orbital Method Reveals New Insight into the Chemical Nature of GPCR–Ligand Interactions BioXFEL Publications |
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07 Dec 2015 |
46 |
The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor BioXFEL Publications |
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03 Nov 2015 |
47 |
Nucleation and Growth of Membrane Protein CrystalsIn Meso—A Fluorescence Microscopy Study BioXFEL Publications |
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02 Nov 2015 |
48 |
Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor BioXFEL Publications |
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30 Sep 2015 |
49 |
Serial femtosecond X-ray diffraction of enveloped virus microcrystals BioXFEL Publications |
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21 Aug 2015 |
50 |
Serial femtosecond crystallography of soluble proteins in lipidic cubic phase BioXFEL Publications |
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04 Aug 2015 |
51 |
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser BioXFEL Publications |
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22 Jul 2015 |
52 |
A novel inert crystal delivery medium for serial femtosecond crystallography BioXFEL Publications |
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29 Jun 2015 |
53 |
Structure of the Angiotensin Receptor Revealed by Serial Femtosecond Crystallography BioXFEL Publications |
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25 Apr 2015 |
54 |
Two disparate ligand-binding sites in the human P2Y1 receptor BioXFEL Publications |
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30 Mar 2015 |
55 |
Fluorescence Recovery After Photobleaching in Lipidic Cubic Phase (LCP-FRAP) BioXFEL Publications |
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22 Mar 2015 |
56 |
GPCR structure, function, drug discovery and crystallography: report from Academia-Industry International Conference (UK Royal Society) Chicheley Hall, 1–2 September 2014 BioXFEL Publications |
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13 Mar 2015 |
57 |
Structural basis for bifunctional peptide recognition at human δ-opioid receptor BioXFEL Publications |
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16 Feb 2015 |
58 |
Lipidic cubic phase serial millisecond crystallography using synchrotron radiation BioXFEL Publications |
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02 Jan 2015 |
59 |
Generic GPCR residue numbers – aligning topology maps while minding the gaps BioXFEL Publications |
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22 Dec 2014 |
60 |
Preparation of microcrystals in lipidic cubic phase for serial femtosecond crystallography BioXFEL Publications |
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14 Aug 2014 |
61 |
Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography BioXFEL Publications |
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14 Feb 2014 |
62 |
Integrated nonlinear optical imaging microscope for on-axis crystal detection and centering at a synchrotron beamline BioXFEL Publications |
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02 May 2013 |
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Towards protein-crystal centering using second-harmonic generation (SHG) microscopy BioXFEL Publications |
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18 Apr 2013 |
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Nonlinear Optical Imaging of Integral Membrane Protein Crystals in Lipidic Mesophases BioXFEL Publications |
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21 Dec 2009 |