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Rescue of conformational dynamics in enzyme catalysis by directed evolution

By Renee Otten, Lin Liu, Lillian R. Kenner, Michael W. Clarkson, David Mavor, Dan S. Tawfik, Dorothee Kern, James Fraser1

1. University of California-San Francisco

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Category

BioXFEL Publications

Published on

Type

journal-article

Author

Renee Otten and Lin Liu and Lillian R. Kenner and Michael W. Clarkson and David Mavor and Dan S. Tawfik and Dorothee Kern and James S. Fraser

Citation

Otten, R. et al., 2018. Rescue of conformational dynamics in enzyme catalysis by directed evolution. Nature Communications, 9(1). Available at: http://dx.doi.org/10.1038/s41467-018-03562-9.

DOI

http://dx.doi.org/10.1038/s41467-018-03562-9

Funding

NSF-STC Biology with X-ray Lasers (NSF-1231306)