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XFEL structures of the influenza M2 proton channel: Room temperature water networks and insights into proton conduction

By Jessica L. Thomaston, Rahel Woldeyes1, Takanori Nakane, Ayumi Yamashita, Tomoyuki Tanaka, Kotaro Koiwai, Aaron S. Brewster, Benjamin A. Barad, Yujie Chen2, Thomas Lemmin, Monarin Uervirojnangkoorn, Toshi Arima, Jun Kobayashi, Tetsuya Masuda, Mamoru Suzuki, Michihiro Sugahara, Nicholas K. Sauter, Rie Tanaka, Osamu Nureki, Kensuke Tono, Yasumasa Joti, Eriko Nango, So Iwata, Fumiaki Yumoto, James Fraser3, William F. DeGrado

1. University of California - San Francisco 2. Cornell University 3. University of California-San Francisco

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Category

BioXFEL Publications

Published on

Type

journal-article

Author

Jessica L. Thomaston and Rahel A. Woldeyes and Takanori Nakane and Ayumi Yamashita and Tomoyuki Tanaka and Kotaro Koiwai and Aaron S. Brewster and Benjamin A. Barad and Yujie Chen and Thomas Lemmin and Monarin Uervirojnangkoorn and Toshi Arima and Jun Kobayashi and Tetsuya Masuda and Mamoru Suzuki and Michihiro Sugahara and Nicholas K. Sauter and Rie Tanaka and Osamu Nureki and Kensuke Tono and Yasumasa Joti and Eriko Nango and So Iwata and Fumiaki Yumoto and James S. Fraser and William F. DeGrado

Citation

Thomaston, J.L. et al., 2017. XFEL structures of the influenza M2 proton channel: Room temperature water networks and insights into proton conduction. Proceedings of the National Academy of Sciences, 114(51), pp.13357–13362. Available at: http://dx.doi.org/10.1073/pnas.1705624114.

DOI

http://dx.doi.org/10.1073/pnas.1705624114

Funding

NSF-STC Biology with X-ray Lasers (NSF-1231306)