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Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance

By Kaitlyn Tsai, Vanja Stojković, Lianet Noda-Garcia, Iris Diane Young¹, Alexander G Myasnikov, Jordan Kleinman, Ali Palla, Stephen N Floor, Adam Frost, James Fraser², Dan S Tawfik, Danica Galonić Fujimori

1. University of California - San Francisco 2. University of California-San Francisco

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Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance

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