What's New: Fiscal Year 2016

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  1. Nucleation and Growth of Membrane Protein CrystalsIn Meso—A Fluorescence Microscopy Study

    02 Nov 2015 | BioXFEL Publications | Contributor(s): Andrey Bogorodskiy, Fedor Frolov, Alexey Mishin, Ekaterina Round, Vitaly Polovinkin, Vadim Cherezov, Valentin Gordeliy, Georg Büldt, Thomas Gensch, Valentin Borshchevskiy

    journal-article http://dx.doi.org/10.1021/acs.cgd.5b01061 Bogorodskiy, A. et al., 2015. Nucleation and Growth of Membrane Protein CrystalsIn Meso—A Fluorescence Microscopy Study. Crystal Growth & …

    https://www.bioxfel.org/resources/1265

  2. Crystal Structure of the Zorbamycin-Binding Protein ZbmA, the Primary Self-Resistance Element in Streptomyces flavoviridis ATCC21892

    29 Oct 2015 | BioXFEL Publications | Contributor(s): Jeffrey D. Rudolf, Lance Bigelow, Changsoo Chang, Marianne E. Cuff, Jeremy R. Lohman, Chin-Yuan Chang, Ming Ma, Dong Yang, Shonda Clancy, Gyorgy Babnigg, Andrzej Joachimiak, George Phillips, Ben Shen

    http://dx.doi.org/10.1021/acs.biochem.5b01008 Jeffrey D. Rudolf and Lance Bigelow and Changsoo Chang and Marianne E. Cuff and Jeremy R. Lohman and Chin-Yuan Chang and Ming Ma and Dong Yang and Shonda …

    https://www.bioxfel.org/resources/1087

  3. Exposing Hidden Alternative Backbone Conformations in X-ray Crystallography Using qFit

    27 Oct 2015 | BioXFEL Publications | Contributor(s): Daniel A. Keedy, James Fraser, Henry Van Den Bedem

    http://dx.doi.org/10.1371/journal.pcbi.1004507 Daniel A. Keedy and James S. Fraser and Henry van den Bedem Keedy, D.A., Fraser, J.S. & van den Bedem, H., 2015. Exposing Hidden Alternative Backbone …

    https://www.bioxfel.org/resources/975

  4. Accurate determination of segmented X-ray detector geometry

    22 Oct 2015 | BioXFEL Publications | Contributor(s): Oleksandr Yefanov, Valerio Mariani, Cornelius Gati, Thomas A. White, Henry Chapman, Anton Barty

    http://dx.doi.org/10.1364/oe.23.028459 Oleksandr Yefanov and Valerio Mariani and Cornelius Gati and Thomas A. White and Henry N. Chapman and Anton Barty Yefanov, O. et al., 2015. Accurate …

    https://www.bioxfel.org/resources/861

  5. Structure of an RNA polymerase II preinitiation complex

    20 Oct 2015 | BioXFEL Publications | Contributor(s): Kenji Murakami, Kuang-Lei Tsai, Nir Kalisman, David Bushnell, Francisco J. Asturias, Roger Kornberg

    journal-article http://dx.doi.org/10.1073/pnas.1518255112 Murakami, K. et al., 2015. Structure of an RNA polymerase II preinitiation complex. Proceedings of the National Academy of Sciences, …

    https://www.bioxfel.org/resources/1323

  6. Imaging of Objects by Coherent Diffraction of X-Ray FEL Pulses

    03 Oct 2015 | BioXFEL Publications | Contributor(s): Richard Kirian, Henry Chapman

    http://dx.doi.org/10.1007/978-3-319-04507-8_27-1 Richard A. Kirian and Henry N. Chapman Kirian, R.A. & Chapman, H.N., 2015. Imaging of Objects by Coherent Diffraction of X-Ray FEL Pulses. Synchrotron …

    https://www.bioxfel.org/resources/1069

  7. Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography

    30 Sep 2015 | BioXFEL Publications | Contributor(s): Daniel A Keedy, Lillian R Kenner, Matthew Warkentin, Rahel Woldeyes, Jesse B Hopkins, Michael Thompson, Aaron S Brewster, Andrew H Van Benschoten, Elizabeth L Baxter, Monarin Uervirojnangkoorn, Scott E McPhillips, Jinhu Song, Roberto Alonso-Mori, James Holton, William I Weis, Axel T Brunger, S Michael Soltis, Henrik Lemke, Ana Gonzalez, Nicholas K Sauter, Aina E Cohen, Henry Van Den Bedem, Robert E Thorne, James Fraser

    Determining the interconverting conformations of dynamic proteins in atomic detail is a major challenge for structural biology. Conformational heterogeneity in the active site of the dynamic enzyme …

    https://www.bioxfel.org/resources/878

  8. Structural and evolutionary relationships of “AT-less” type I polyketide synthase ketosynthases

    29 Sep 2015 | BioXFEL Publications | Contributor(s): Jeremy R. Lohman, Ming Ma, Jerzy Osipiuk, Boguslaw Nocek, Youngchang Kim, Changsoo Chang, Marianne Cuff, Jamey Mack, Lance Bigelow, Hui Li, Michael Endres, Gyorgy Babnigg, Andrzej Joachimiak, George Phillips, Ben Shen

    http://dx.doi.org/10.1073/pnas.1515460112 Jeremy R. Lohman and Ming Ma and Jerzy Osipiuk and Boguslaw Nocek and Youngchang Kim and Changsoo Chang and Marianne Cuff and Jamey Mack and Lance Bigelow …

    https://www.bioxfel.org/resources/931

  9. Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor

    29 Sep 2015 | BioXFEL Publications | Contributor(s): Haitao Zhang, Hamiyet Unal, Russell Desnoyer, Gye Won Han, Nilkanth N Patel, Vsevolod Katritch, Sadashiva S. Karnik, Vadim Cherezov, Raymond C. Stevens

    http://dx.doi.org/10.1074/jbc.m115.689000 Haitao Zhang and Hamiyet Unal and Russell Desnoyer and Gye Won Han and Nilkanth Patel and Vsevolod Katritch and Sadashiva S. Karnik and Vadim Cherezov and …

    https://www.bioxfel.org/resources/934

  10. Towards phasing using high X-ray intensity

    29 Sep 2015 | BioXFEL Publications | Contributor(s): Lorenzo Galli, Sang-Kil Son, Thomas R. M. Barends, Thomas A. White, Anton Barty, Sabine Botha, Sébastien Boutet, Carl Caleman, R. Bruce Doak, Max H. Nanao, Karol Nass, Robert L. Shoeman, Nicusor Timneanu, Robin Santra, Ilme Schlichting, Henry Chapman

    X-ray free-electron lasers (XFELs) show great promise for macromolecular structure determination from sub-micrometre-sized crystals, using the emerging method of serial femtosecond crystallography. …

    https://www.bioxfel.org/resources/958

  11. Molecular architecture of the yeast Mediator complex

    24 Sep 2015 | BioXFEL Publications | Contributor(s): Philip J Robinson, Michael J Trnka, Riccardo Pellarin, Charles H Greenberg, David Bushnell, Ralph Davis, Alma L Burlingame, Andrej Sali, Roger Kornberg

    http://dx.doi.org/10.7554/elife.08719 Philip J Robinson and Michael J Trnka and Riccardo Pellarin and Charles H Greenberg and David A Bushnell and Ralph Davis and Alma L Burlingame and Andrej Sali …

    https://www.bioxfel.org/resources/885

  12. Hollow cone illumination for fast TEM, and outrunning damage with electrons

    23 Sep 2015 | BioXFEL Publications | Contributor(s): J C H Spence, G Subramanian, P Musumeci

    http://dx.doi.org/10.1088/0953-4075/48/21/214003 J C H Spence and G Subramanian and P Musumeci Spence, J.C.H., Subramanian, G. & Musumeci, P., 2015. Hollow cone illumination for fast TEM, and …

    https://www.bioxfel.org/resources/862

  13. Image reconstruction in serial femtosecond nanocrystallography using x-ray free-electron lasers

    21 Sep 2015 | BioXFEL Publications | Contributor(s): Joe Chen, Richard Kirian, Kenneth R. Beyerlein, Richard J. Bean, Andrew J. Morgan, Oleksandr M. Yefanov, Romain D. Arnal, David H. Wojtas, Phil J. Bones, Henry Chapman, John Spence, Rick P. Millane

    http://dx.doi.org/10.1117/12.2187610 Joe P. J. Chen and Richard A. Kirian and Kenneth R. Beyerlein and Richard J. Bean and Andrew J. Morgan and Oleksandr M. Yefanov and Romain D. Arnal and David H. …

    https://www.bioxfel.org/resources/965

  14. Strongly aligned gas-phase molecules at free-electron lasers

    17 Sep 2015 | BioXFEL Publications | Contributor(s): Thomas Kierspel, Joss Wiese, Terry Mullins, Joseph Robinson, Andy Aquila, Anton Barty, Richard Bean, Rebecca Boll, Sébastien Boutet, Philip Bucksbaum, Henry Chapman, Lauge Christensen, Alan Fry, Mark S. Hunter, Jason E Koglin, Mengning Liang, Valerio Mariani, Andrew Morgan, Adi Natan, Vladimir Petrovic, Daniel Rolles, Artem Rudenko, Kirsten Schnorr, Henrik Stapelfeldt, Stephan Stern, Jan Thøgersen, Chun Hong Yoon, Fenglin Wang, Sebastian Trippel, Jochen Küpper

    http://dx.doi.org/10.1088/0953-4075/48/20/204002 Thomas Kierspel and Joss Wiese and Terry Mullins and Joseph Robinson and Andy Aquila and Anton Barty and Richard Bean and Rebecca Boll and Sébastien …

    https://www.bioxfel.org/resources/936

  15. Synchrotron topographic evaluation of strain around craters generated by irradiation with X-ray pulses from free electron laser with different intensities

    11 Sep 2015 | BioXFEL Publications | Contributor(s): W. Wierzchowski, K. Wieteska, R. Sobierajski, D. Klinger, J. Pełka, D. Żymierska, C. Paulmann, S.P. Hau-Riege, R.A. London, A. Graf, T. Burian, J. Chalupský, J. Gaudin, J. Krzywinski, S. Moeller, M. Messerschmidt, J. Bozek, Ch. Bostedt

    http://dx.doi.org/10.1016/j.nimb.2015.07.115 W. Wierzchowski and K. Wieteska and R. Sobierajski and D. Klinger and J. Pełka and D. Żymierska and C. Paulmann and S.P. Hau-Riege and R.A. London and …

    https://www.bioxfel.org/resources/1082

  16. Structure of the toxic core of α-synuclein from invisible crystals

    08 Sep 2015 | BioXFEL Publications | Contributor(s): Jose A. Rodriguez, Magdalena I. Ivanova, Michael R. Sawaya, Duilio Cascio, Francis E. Reyes, Dan Shi, Smriti Sangwan, Elizabeth L. Guenther, Lisa M. Johnson, Meng Zhang, Lin Jiang, Mark A. Arbing, Brent L. Nannenga, Johan Hattne, Julian Whitelegge, Aaron S. Brewster, Marc Messerschmidt, Sébastien Boutet, Nicholas K. Sauter, Tamir Gonen, David S. Eisenberg

    http://dx.doi.org/10.1038/nature15368 Jose A. Rodriguez and Magdalena I. Ivanova and Michael R. Sawaya and Duilio Cascio and Francis E. Reyes and Dan Shi and Smriti Sangwan and Elizabeth L. Guenther …

    https://www.bioxfel.org/resources/1091

  17. X-ray two-photon absorption with high fluence XFEL pulses

    07 Sep 2015 | BioXFEL Publications | Contributor(s): J Hoszowska, J Szlachetko, J-Cl Dousse, W Błachucki, Y Kayser, Ch Milne, M Pajek, S Boutet, M Messerschmidt, G Williams, C T Chantler

    http://dx.doi.org/10.1088/1742-6596/635/10/102009 J Hoszowska and J Szlachetko and J-Cl Dousse and W Błachucki and Y Kayser and Ch Milne and M Pajek and S Boutet and M Messerschmidt and G Williams …

    https://www.bioxfel.org/resources/938

  18. Real-time observation of the initiation of RNA polymerase II transcription

    02 Sep 2015 | BioXFEL Publications | Contributor(s): Furqan M. Fazal, Cong A. Meng, Kenji Murakami, Roger Kornberg, Steven M. Block

    journal-article http://dx.doi.org/10.1038/nature14882 Fazal, F.M. et al., 2015. Real-time observation of the initiation of RNA polymerase II transcription. Nature, 525(7568), pp.274–277. Available …

    https://www.bioxfel.org/resources/1270