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Enzyme intermediates captured “on the fly” by mix-and-inject serial crystallography

By Jose L. Olmos, Suraj Pandey1, Jose M. Martin-Garcia, George Douglas Calvey, Andrea Katz, Juraj Knoska, Christopher Kupitz2, Mark S. Hunter2, Mengning Liang, Dominik Oberthuer, Oleksandr Yefanov, Max Oliver Wiedorn3, Michael Heyman, Mark Holl, Kanupriya Pande1, Anton Barty, Mitchell Miller4, Stephan Stern, Shatabdi Roy-Chowdhury5, Jesse David Coe5, Nirupa Nagaratnam5, James D Zook5, Jacob Christopher Verburgt6, Tyler Norwood, Ishwor Poudyal1, David Xu, Jason Koglin, Matthew H. Seaberg, Yun Zhao5, Saša Bajt, Thomas Grant, Valerio Mariani, Garrett Charles Nelson5, GANESH SUBRAMANIAN5, Euiyoung Bae, Raimund Fromme, Russell Fung7, Peter Schwander7, Matthias Frank8, Thomas A. White, Uwe Weierstall5, Nadia Zatsepin5, John Spence5, Petra Fromme5, Henry Chapman3, Lois Pollack9, Lee Tremblay10, Abbas Ourmazd7, George Phillips4, Marius Schmidt1

1. University of Wisconsin - Milwaukee 2. SLAC National Accelerator Laboratory 3. Center for Free-Electron Laser Science 4. Rice University 5. Arizona State University 6. BioXFEL Undergraduate Summer Intern 7. University of Wisconsin-Milwaukee 8. Lawrence Livermore National Laboratory 9. Cornell University 10. 4Marbles Inc.

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Category

BioXFEL Publications

Published on

Type

journal-article

Author

Jose L. Olmos and Suraj Pandey and Jose M. Martin-Garcia and George Calvey and Andrea Katz and Juraj Knoska and Christopher Kupitz and Mark S. Hunter and Mengning Liang and Dominik Oberthuer and Oleksandr Yefanov and Max Wiedorn and Michael Heyman and Mark Holl and Kanupriya Pande and Anton Barty and Mitchell D. Miller and Stephan Stern and Shatabdi Roy-Chowdhury and Jesse Coe and Nirupa Nagaratnam and James Zook and Jacob Verburgt and Tyler Norwood and Ishwor Poudyal and David Xu and Jason Koglin and Matthew H. Seaberg and Yun Zhao and Saša Bajt and Thomas Grant and Valerio Mariani and Garrett Nelson and Ganesh Subramanian and Euiyoung Bae and Raimund Fromme and Russell Fung and Peter Schwander and Matthias Frank and Thomas A. White and Uwe Weierstall and Nadia Zatsepin and John Spence and Petra Fromme and Henry N. Chapman and Lois Pollack and Lee Tremblay and Abbas Ourmazd and George N. Phillips and Marius Schmidt

Citation

Olmos, J.L. et al., 2018. Enzyme intermediates captured “on the fly” by mix-and-inject serial crystallography. BMC Biology, 16(1). Available at: http://dx.doi.org/10.1186/s12915-018-0524-5.

DOI

http://dx.doi.org/10.1186/s12915-018-0524-5

Funding

NSF-STC Biology with X-ray Lasers (NSF-1231306)