What's New: Calendar year 2016

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  1. Protein Crystallization in an Actuated Microfluidic Nanowell Device

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    25 Feb 2016 | BioXFEL Publications | Contributor(s): Bahige G. Abdallah, Shatabdi Roy-Chowdhury, Raimund Fromme, Petra Fromme, Alexandra Ros

    http://dx.doi.org/10.1021/acs.cgd.5b01748 Bahige G. Abdallah and Shatabdi Roy-Chowdhury and Raimund Fromme and Petra Fromme and Alexandra Ros Abdallah, B.G. et al., 2016. Protein Crystallization in …

    https://www.bioxfel.org/resources/915

  2. Polyclonal Antibody Production for Membrane Proteins via Genetic Immunization

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    24 Feb 2016 | BioXFEL Publications | Contributor(s): Debra T. Hansen, Mark D. Robida, Felicia M. Craciunescu, Andrey V. Loskutov, Katerina Dörner, John-Charles Rodenberry, Xiao Wang, Tien L. Olson, Hetal Patel, Petra Fromme, Kathryn F. Sykes

    http://dx.doi.org/10.1038/srep21925 Debra T. Hansen and Mark D. Robida and Felicia M. Craciunescu and Andrey V. Loskutov and Katerina Dörner and John-Charles Rodenberry and Xiao Wang and Tien L. …

    https://www.bioxfel.org/resources/1099

  3. Reconstructing three-dimensional helical structure with an X-ray free electron laser

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    23 Feb 2016 | BioXFEL Publications | Contributor(s): M. Uddin

    Recovery of three-dimensional structure from single-particle X-ray scattering of completely randomly oriented diffraction patterns as predicted a few decades ago has been realized owing to the advent …

    https://www.bioxfel.org/resources/1295

  4. Loop dynamics of thymidine diphosphate-rhamnose 3′-O-methyltransferase (CalS11), an enzyme in calicheamicin biosynthesis

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    18 Feb 2016 | BioXFEL Publications | Contributor(s): Lu Han, Shanteri Singh, Jon S. Thorson, George Phillips

    http://dx.doi.org/10.1063/1.4941368 Lu Han and Shanteri Singh and Jon S. Thorson and George N. Phillips Han, L. et al., 2016. Loop dynamics of thymidine diphosphate-rhamnose 3′-O-methyltransferase …

    https://www.bioxfel.org/resources/929

  5. The Structural History of RNA Polymerase Transcription Machinery

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    18 Feb 2016 | Teaching Materials | Contributor(s): Roger Kornberg

    Dr. Roger Kornberg, 2006 Nobel Laureate in Chemistry, discusses the structural history of the RNA polymerase II transcription machinery and how it played a role in his successful career.

    https://www.bioxfel.org/resources/914

  6. Structural Studies of the Human Kappa Opioid Receptor Active State Conformations

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    16 Feb 2016 | BioXFEL Publications | Contributor(s): Ming-Yue Lee, Nilkanth N Patel, Vsevolod Katritch, Raymond C. Stevens, Vadim Cherezov

    http://dx.doi.org/10.1016/j.bpj.2015.11.275 Ming-Yue Lee and Nilkanth Patel and Vsevolod Katritch and Raymond C. Stevens and Vadim Cherezov Lee, M.-Y. et al., 2016. Structural Studies of the Human …

    https://www.bioxfel.org/resources/1077

  7. An in Vitro Investigation of Globin Folding and Expression

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    16 Feb 2016 | BioXFEL Publications | Contributor(s): Premila P. Samuel, William Ou, George Phillips, John S. Olson

    http://dx.doi.org/10.1016/j.bpj.2015.11.1166 journal-article Samuel, P.P. et al., 2016. An in Vitro Investigation of Globin Folding and Expression. Biophysical Journal, 110(3), p.209a–210a. …

    https://www.bioxfel.org/resources/1420

  8. Preparation and Delivery of Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography

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    16 Feb 2016 | BioXFEL Publications | Contributor(s): Andrii Ishchenko, Vadim Cherezov, Wei Liu

    http://dx.doi.org/10.1016/j.bpj.2015.11.383 Andrii Ishchenko and Vadim Cherezov and Wei Liu Ishchenko, A., Cherezov, V. & Liu, W., 2016. Preparation and Delivery of Microcrystals in Lipidic Cubic …

    https://www.bioxfel.org/resources/1078

  9. Continuous Changes in Structure Mapped by Manifold Embedding of Single-Particle Data in Cryo-EM

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    14 Feb 2016 | BioXFEL Publications | Contributor(s): Joachim Frank, Abbas Ourmazd

    http://dx.doi.org/10.1016/j.ymeth.2016.02.007 Joachim Frank and Abbas Ourmazd Frank, J. & Ourmazd, A., 2016. Continuous Changes in Structure Mapped by Manifold Embedding of Single-Particle Data in …

    https://www.bioxfel.org/resources/913

  10. Macromolecular diffractive imaging using imperfect crystals

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    10 Feb 2016 | BioXFEL Publications | Contributor(s): Kartik Ayyer, Oleksandr M. Yefanov, Dominik Oberthür, Shatabdi Roy-Chowdhury, Lorenzo Galli, Valerio Mariani, Shibom Basu, Jesse David Coe, Chelsie E Conrad, Raimund Fromme, Alexander Schaffer, Katerina Dörner, Daniel James, Christopher Kupitz, Markus Metz, Garrett Charles Nelson, Paulraj Lourdu Xavier, Kenneth R. Beyerlein, Marius Schmidt, Iosifina Sarrou, John Spence, Uwe Weierstall, Thomas A. White, Jay-How Yang, Yun Zhao, Mengning Liang, Andrew Aquila, Mark S. Hunter, Joseph S. Robinson, Jason E. Koglin, Sébastien Boutet, Petra Fromme, Anton Barty, Henry Chapman

    http://dx.doi.org/10.1038/nature16949 Kartik Ayyer and Oleksandr M. Yefanov and Dominik Oberthür and Shatabdi Roy-Chowdhury and Lorenzo Galli and Valerio Mariani and Shibom Basu and Jesse Coe and …

    https://www.bioxfel.org/resources/912

  11. Concentration of Sindbis virus with optimized gradient insulator-based dielectrophoresis

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    08 Feb 2016 | BioXFEL Publications | Contributor(s): Jie Ding, Robert M Lawrence, Paul V. Jones, Brenda Hogue, Mark A. Hayes

    http://dx.doi.org/10.1039/c5an02430g Jie Ding and Robert M. Lawrence and Paul V. Jones and Brenda G. Hogue and Mark A. Hayes Ding, J. et al., 2016. Concentration of Sindbis virus with optimized …

    https://www.bioxfel.org/resources/911

  12. CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites

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    05 Feb 2016 | BioXFEL Publications | Contributor(s): Peter Cimermancic, Patrick Weinkam, T. Justin Rettenmaier, Leon Bichmann, Daniel A. Keedy, Rahel Woldeyes, Dina Schneidman-Duhovny, Omar N. Demerdash, Julie C. Mitchell, James A. Wells, James Fraser, Andrej Sali

    http://dx.doi.org/10.1016/j.jmb.2016.01.029 Peter Cimermancic and Patrick Weinkam and T. Justin Rettenmaier and Leon Bichmann and Daniel A. Keedy and Rahel A. Woldeyes and Dina Schneidman-Duhovny and …

    https://www.bioxfel.org/resources/910

  13. Transient lattice contraction in the solid-to-plasma transition

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    29 Jan 2016 | BioXFEL Publications | Contributor(s): Ken R. Ferguson, Maximilian Bucher, Tais Gorkhover, Sébastien Boutet, Hironobu Fukuzawa, Jason E. Koglin, Yoshiaki Kumagai, Alberto Lutman, Agostino Marinelli, Marc Messerschmidt, Kiyonobu Nagaya, Jim Turner, Kiyoshi Ueda, Garth J. Williams, Philip H. Bucksbaum, Christoph Bostedt

    http://dx.doi.org/10.1126/sciadv.1500837 Ken R. Ferguson and Maximilian Bucher and Tais Gorkhover and Sébastien Boutet and Hironobu Fukuzawa and Jason E. Koglin and Yoshiaki Kumagai and Alberto …

    https://www.bioxfel.org/resources/909

  14. One dimensional focusing with high numerical aperture multilayer Laue lens

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    28 Jan 2016 | BioXFEL Publications | Contributor(s): Saša Bajt, Mauro Prasciolu, Andrew J. Morgan, Henry Chapman, Jacek Krzywinski, Andrzej Andrejczuk

    http://dx.doi.org/10.1063/1.4937543 Saša Bajt and Mauro Prasciolu and Andrew J. Morgan and Henry N. Chapman and Jacek Krzywinski and Andrzej Andrejczuk Bajt, S. et al., 2016. One dimensional …

    https://www.bioxfel.org/resources/928

  15. Imaging of Objects by Coherent Diffraction of X-Ray Free-Electron Laser Pulses

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    28 Jan 2016 | BioXFEL Publications | Contributor(s): Richard Kirian, Henry Chapman

    http://dx.doi.org/10.1007/978-3-319-04507-8_27-2 Richard A. Kirian and Henry N. Chapman Kirian, R.A. & Chapman, H.N., 2015. Imaging of Objects by Coherent Diffraction of X-Ray Free-Electron Laser …

    https://www.bioxfel.org/resources/1070

  16. Femtosecond and nanometre visualization of structural dynamics in superheated nanoparticles

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    25 Jan 2016 | BioXFEL Publications | Contributor(s): Tais Gorkhover, Sebastian Schorb, Ryan Coffee, Marcus Adolph, Lutz Foucar, Daniela Rupp, Andrew Aquila, John D. Bozek, Sascha W. Epp, Benjamin Erk, Lars Gumprecht, Lotte Holmegaard, Andreas Hartmann, Robert Hartmann, Günter Hauser, Peter Holl, Andre Hömke, Per Johnsson, Nils Kimmel, Kai-Uwe Kühnel, Marc Messerschmidt, Christian Reich, Arnaud Rouzée, Benedikt Rudek, Carlo Schmidt, Joachim Schulz, Heike Soltau, Stephan Stern, Georg Weidenspointner, Bill White, Jochen Küpper, Lothar Strüder, Ilme Schlichting, Joachim Ullrich, Daniel Rolles, Artem Rudenko, Thomas Möller, Christoph Bostedt

    http://dx.doi.org/10.1038/nphoton.2015.264 Tais Gorkhover and Sebastian Schorb and Ryan Coffee and Marcus Adolph and Lutz Foucar and Daniela Rupp and Andrew Aquila and John D. Bozek and Sascha W. Epp …

    https://www.bioxfel.org/resources/908

  17. Melatonin receptor activation increases glutamatergic synaptic transmission in the rat medial lateral habenula

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    22 Jan 2016 | BioXFEL Publications | Contributor(s): Katherine M. Evely, Randall L. Hudson, Margarita L. Dubocovich, Samir Haj-dahmane

    http://dx.doi.org/10.1002/syn.21892 journal-article Evely, K.M. et al., 2016. Melatonin receptor activation increases glutamatergic synaptic transmission in the rat medial lateral habenula. …

    https://www.bioxfel.org/resources/1667

  18. Serial femtosecond crystallography opens new avenues for Structural Biology

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    20 Jan 2016 | BioXFEL Publications | Contributor(s): Jesse David Coe, Petra Fromme

    http://dx.doi.org/10.2174/0929866523666160120152937 Jesse Coe and Petra Fromme Coe, J. & Fromme, P., 2016. Serial femtosecond crystallography opens new avenues for Structural Biology. PPL, 23(3), …

    https://www.bioxfel.org/resources/981

  19. The Role of Correlation and Solvation in Ion Interactions with B-DNA

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    19 Jan 2016 | BioXFEL Publications | Contributor(s): Maria L. Sushko, Dennis G. Thomas, Suzette A. Pabit, Lois Pollack, Alexey V. Onufriev, Nathan A. Baker

    journal-article http://dx.doi.org/10.1016/j.bpj.2015.12.011 Sushko, M.L. et al., 2016. The Role of Correlation and Solvation in Ion Interactions with B-DNA. Biophysical Journal, 110(2), …

    https://www.bioxfel.org/resources/1306

  20. In cellulo serial crystallography of alcohol oxidase crystals inside yeast cells

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    11 Jan 2016 | BioXFEL Publications | Contributor(s): Arjen J. Jakobi, Daniel M. Passon, Kèvin Knoops, Francesco Stellato, Mengning Liang, Thomas A. White, Thomas Seine, Marc Messerschmidt, Henry Chapman, Matthias Wilmanns

    The possibility of using femtosecond pulses from an X-ray free-electron laser to collect diffraction data from protein crystals formed in their native cellular organelle has been explored. X-ray …

    https://www.bioxfel.org/resources/907

  21. Computational crystallization

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    11 Jan 2016 | BioXFEL Publications | Contributor(s): Irem Altan, Patrick Charbonneau, Edward Snell

    http://dx.doi.org/10.1016/j.abb.2016.01.004 Irem Altan and Patrick Charbonneau and Edward H. Snell Altan, I., Charbonneau, P. & Snell, E.H., 2016. Computational crystallization. Archives of …

    https://www.bioxfel.org/resources/1076

  22. Serial femtosecond crystallography on in vivo grown crystals at SACLA - developments and results

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    05 Jan 2016 | BioXFEL Publications | Contributor(s): Leonard M. G. Chavas, Sasa Bajt, Lars Gumprecht, Henry Chapman

    http://dx.doi.org/10.1107/s2053273315097831 Leonard M. G. Chavas and Sasa Bajt and Lars Gumprecht and Henry N. Chapman Chavas, L.M.G. et al., 2015. Serial femtosecond crystallography on in vivo …

    https://www.bioxfel.org/resources/959

  23. Towards a generalised approach for the time-resolved crystallographic study of enzymes

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    05 Jan 2016 | BioXFEL Publications | Contributor(s): Diana C. F. Monteiro, Vijay Patel, Christopher P. Bartlett, Shingo Nozaki, Thomas D. Grant, James A. Gowdy, Gary S. Thompson, Arnout P. Kalverda, Edward Snell, Hironori Niki, Arwen R. Pearson, Michael E. Webb

    http://dx.doi.org/10.1107/s205327331509957x Diana C. F. Monteiro and Vijay Patel and Christopher P. Bartlett and Shingo Nozaki and Thomas D. Grant and James A. Gowdy and Gary S. Thompson and Arnout …

    https://www.bioxfel.org/resources/960

  24. Phase retrieval for randomly terminated finite crystals

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    05 Jan 2016 | BioXFEL Publications | Contributor(s): Joe Chen, Rick A. Kirian, Richard J. Bean, Kenneth R. Beyerlein, Miriam Barthelmess, Chun Hong Yoon, Fenglin Wang, Flavio Capotondi, Emanuele Pedersoli, Anton Barty, Henry Chapman, Philip J. Bones, Romain D. Arnal, Rick P. Millane, John Spence

    http://dx.doi.org/10.1107/s2053273315099714 Joe P. J. Chen and Rick A. Kirian and Richard J. Bean and Kenneth R. Beyerlein and Miriam Barthelmess and Chun Hong Yoon and Fenglin Wang and Flavio …

    https://www.bioxfel.org/resources/961

  25. Improving resolution in serial crystallography

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    05 Jan 2016 | BioXFEL Publications | Contributor(s): Kartik Ayyer, Oleksandr M. Yefanov, Dominik Oberthuer, Shatabdi Roy Chowdhury, Lorenzo Galli, Valerio Mariani, Shibom Basu, Jesse David Coe, Chelsie E Conrad, Raimund Fromme, Katerina Doerner, Matthias Frank, Daniel James, Christopher Kupitz, Markus Metz, Garrett Charles Nelson, Xavier L. Paulraj, Kenneth Beyerlein, Marius Schmidt, Iosifina Sarrou, John Spence, Uwe Weierstall, Thomas A. White, Jayhow Yang, Nadia Zatsepin, Yun Zhao, Mengning Liang, Andrew Aquila, Mark S. Hunter, Joseph S. Robinson, Jason E. Koglin, Sébastien Boutet, Petra Fromme, Anton Barty, Henry Chapman

    http://dx.doi.org/10.1107/s2053273315099738 Kartik Ayyer and Oleksandr M. Yefanov and Dominik Oberthuer and Shatabdi Chowdhury and Lorenzo Galli and Valerio Mariani and Shibom Basu and Jesse Coe and …

    https://www.bioxfel.org/resources/962

  26. Serial synchrotron crystallography experiments at EMBL beamline P14 at PETRA III

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    05 Jan 2016 | BioXFEL Publications | Contributor(s): Thomas R. Schneider, Gleb Bourenkov, Cornelius Gati, Henry Chapman, Lars Redecke, Ulrich Zander, José A. Marquez, Florent Cipriani

    http://dx.doi.org/10.1107/s2053273315099805 Thomas R. Schneider and Gleb Bourenkov and Cornelius Gati and Henry N. Chapman and Lars Redecke and Ulrich Zander and José A. Marquez and Florent Cipriani …

    https://www.bioxfel.org/resources/963

  27. Interview with Dilano Saldin

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    05 Jan 2016 | Teaching Materials

    Combining data from new facilities with mathematical methods, Professor Dilano Saldin is in pursuit of a technique to determine the structure of molecules without the need for purification …

    https://www.bioxfel.org/resources/868

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