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  1. SFX Data Analysis Workshop at 2015 ACA

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    25 Jul 2015 | Workshops | Contributor(s): Nadia Zatsepin, Tom Grant, Cornelius Gati

    Serial femtosecond crystallography has yielded several major and unique advances in structural biology previously unattainable with conventional technologies, including the potential for sub-picosecond time-resolved crystallographic studies, probing cyclic or even non-cyclic reactions. With the …

  2. SFX Data Reduction and Preprocessing

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    29 Aug 2014 | Teaching Materials

    Anton Barty (CFEL) Photons, detectors and data streams: how to get at the data and what it records. Data reduction and pre-processing: how it works and how to optimize it.

  3. SFX Data Reduction and Preprocessing with Cheetah

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    25 Jul 2015 | Teaching Materials | Contributor(s): Nadia Zatsepin

    Dr. Nadia Zatsepin discusses how to use the software program Cheetah to reduce raw SFX data from LCLS to a set of crystal "hits".

  4. SFX Indexing and Integration with CrystFEL

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    25 Jul 2015 | Teaching Materials

    Dr. Thomas White discusses how to index and integrate serial crystallography images using the CrystFEL software package.

  5. Shape transform phasing of edgy nanocrystals

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    28 Feb 2019 | BioXFEL Publications | Contributor(s): J. P. J. Chen, J. J. Donatelli, K. E. Schmidt, R. A. Kirian

    http://dx.doi.org/10.1107/s205327331900113x Diffraction patterns from small protein crystals illuminated by highly coherent X-rays often contain measurable interference signals between Bragg peaks. This coherent `shape transform' signal introduces enough additional information to allow the …

  6. Side-chain-directed model and map validation for 3D Electron Cryomicroscopy

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    09 Feb 2015 | BioXFEL Publications | Contributor(s): Benjamin A Barad, Nathaniel Echols, Ray Yu-Ruei Wang, Yifan Cheng, Frank DiMaio, Paul D Adams, James Fraser

    Advances in electron cryomicroscopy allow for the building of de novo atomic models into high resolution Coulomb potential maps. While established validation metrics independently assess map quality and model geometry, methods to assess the precise fitting of an atomic model into the map and to …

  7. Signal to noise considerations for single crystal femtosecond time resolved crystallography of the Photoactive Yellow Protein

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    09 Apr 2014 | BioXFEL Publications | Contributor(s): Jasper J. Van Thor, Mark M. Warren, Craig N. Lincoln, Matthieu Chollet, Henrik Till Lemke, David M. Fritz, Marius Schmidt, Jason Tenboer, Zhong Ren, Vukica Srajer, Keith Moffat, Tim Graber

    http://dx.doi.org/10.1039/c4fd00011k Jasper J. van Thor and Mark M. Warren and Craig N. Lincoln and Matthieu Chollet and Henrik Till Lemke and David M. Fritz and Marius Schmidt and Jason Tenboer and Zhong Ren and Vukica Srajer and Keith Moffat and Tim Graber Van Thor, J.J. et al., 2014. Signal to …

  8. Silicon Mirrors for High-Intensity X-Ray Pump and Probe Experiments

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    28 May 2014 | BioXFEL Publications | Contributor(s): Tom Pardini, Sébastien Boutet, Joseph Bradley, Tilo Döppner, Luke B. Fletcher, Dennis F. Gardner, Randy M. Hill, Mark S. Hunter, Jacek Krzywinski, Marc Messerschmidt, Arthur E. Pak, Florian Quirin, Klaus Sokolowski-Tinten, Garth J. Williams, Stefan Hau-Riege

    journal-article http://dx.doi.org/10.1103/physrevapplied.1.044007 Pardini, T. et al., 2014. Silicon Mirrors for High-Intensity X-Ray Pump and Probe Experiments. Physical Review Applied, 1(4). Available at: http://dx.doi.org/10.1103/physrevapplied.1.044007. Tom Pardini and Sébastien Boutet and …

  9. Silicon single crystal as back-reflector for high-intensity hard x-rays

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    05 Sep 2014 | BioXFEL Publications | Contributor(s): Tom Pardini, Sébastien Boutet, Joseph Bradley, Tilo Doeppner, Luke B. Fletcher, Dennis F. Gardner, Randy M. Hill, Mark S. Hunter, Jacek Krzywinski, Marc Messerschmidt, Arthur E. Pak, Florian Quirin, Klaus Sokolowski-Tinten, Garth J. Williams, Stefan Hau-Riege

    http://dx.doi.org/10.1117/12.2061087 proceedings-article Pardini, T. et al., 2014. Silicon single crystal as back-reflector for high-intensity hard x-rays S. P. Hau-Riege, S. P. Moeller, & M. Yabashi, eds. X-Ray Free-Electron Lasers: Beam Diagnostics, Beamline Instrumentation, and Applications …

  10. Simple convergent-nozzle aerosol injector for single-particle diffractive imaging with X-ray free-electron lasers

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    19 Jun 2015 | BioXFEL Publications | Contributor(s): R. A. Kirian, S. Awel, N. Eckerskorn, H. Fleckenstein, M. Wiedorn, L. Adriano, S. Bajt, M. Barthelmess, R. Bean, K. R. Beyerlein, L. M. G. Chavas, M. Domaracky, M. Heymann, D. A. Horke, J. Knoska, M. Metz, A. Morgan, D. Oberthuer, N. Roth, T. Sato, P. L. Xavier, O. Yefanov, A. V. Rode, J. Küpper, H. N. Chapman

    http://dx.doi.org/10.1063/1.4922648 R. A. Kirian and S. Awel and N. Eckerskorn and H. Fleckenstein and M. Wiedorn and L. Adriano and S. Bajt and M. Barthelmess and R. Bean and K. R. Beyerlein and L. M. G. Chavas and M. Domaracky and M. Heymann and D. A. Horke and J. Knoska and M. Metz and A. Morgan …

  11. Simulations of single-pulse Laue diffraction from proteins with radiation from synchrotron and XFEL sources

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    15 Nov 2016 | BioXFEL Publications | Contributor(s): Victoria Kabanova, Marius Schmidt, Friedrich Schotte, Marco Cammarata, Michael Wulff

    http://dx.doi.org/10.1107/s2053273316097898 journal-article Kabanova, V. et al., 2016. Simulations of single-pulse Laue diffraction from proteins with radiation from synchrotron and XFEL sources. Acta Crystallographica Section A Foundations and Advances, 72(a1), pp.s142–s142. Available at: …

  12. Simulations on time-resolved structure determination of uncrystallized biomolecules in the presence of shot noise

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    10 Apr 2015 | BioXFEL Publications | Contributor(s): K. Pande, M. Schmidt, P. Schwander, D. K. Saldin

    http://dx.doi.org/10.1063/1.4916980 K. Pande and M. Schmidt and P. Schwander and D. K. Saldin Pande, K. et al., 2015. Simulations on time-resolved structure determination of uncrystallized biomolecules in the presence of shot noise. Structural Dynamics, 2(2), p.024103. Available at: …

  13. Simultaneous retrieval of coherently illuminated defocused objects

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    05 Jul 2018 | BioXFEL Publications | Contributor(s): Joe Chen, Richard Kirian

    http://dx.doi.org/10.1109/ivcnz.2017.8402481 proceedings-article Chen, J.P.J. & Kirian, R.A., 2017. Simultaneous retrieval of coherently illuminated defocused objects. 2017 International Conference on Image and Vision Computing New Zealand (IVCNZ). Available at: …

  14. Single Particle Reconstruction

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    13 Oct 2015 | Teaching Materials

    Dr. Dilano Saldin discusses recent advances in algorithms for single particle reconstruction from solution scattering data at XFELs.

  15. Single-femtosecond atomic-resolution observation of a protein traversing a conical intersection

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    15 Nov 2020 | BioXFEL Publications | Contributor(s): A. Hosseinizadeh, N. Breckwoldt, R. Fung, R. Sepehr, M. Schmidt, P. Schwander, R. Santra, A. Ourmazd

    http://dx.doi.org/10.1101/2020.11.13.382218 The structural dynamics of a molecule are determined by the underlying potential energy landscape. Conical intersections are funnels connecting otherwise separate energy surfaces. Posited almost a century ago 1, conical intersections remain the subject of …

  16. Single-particle imaging by x-ray free-electron lasers—How many snapshots are needed?

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    20 Mar 2020 | BioXFEL Publications | Contributor(s): I. Poudyal, M. Schmidt, P. Schwander

    http://dx.doi.org/10.1063/1.5144516 journal-article Poudyal, I., Schmidt, M. & Schwander, P., 2020. Single-particle imaging by x-ray free-electron lasers—How many snapshots are needed? Structural Dynamics, 7(2), p.024102. Available at: http://dx.doi.org/10.1063/1.5144516. I. Poudyal and M. …

  17. Single-particle imaging without symmetry constraints at an X-ray free-electron laser

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    18 Sep 2018 | BioXFEL Publications | Contributor(s): Max Rose, Sergey Bobkov, Kartik Ayyer, Ruslan P. Kurta, Dmitry Dzhigaev, Young Yong Kim, Andrew J. Morgan, Chun Hong Yoon, Daniel Westphal, Johan Bielecki, Jonas A. Sellberg, Garth Williams, Filipe R.N.C. Maia, Olexander M. Yefanov, Vyacheslav Ilyin, Adrian P. Mancuso, Henry Chapman, Brenda Hogue, Andrew Aquila, Anton Barty, Ivan A. Vartanyants

    http://dx.doi.org/10.1107/s205225251801120x The analysis of a single-particle imaging (SPI) experiment performed at the AMO beamline at LCLS as part of the SPI initiative is presented here. A workflow for the three-dimensional virus reconstruction of the PR772 bacteriophage from measured …

  18. Single-particle imaging without symmetry constraints at an X-ray free-electron laser

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    21 Sep 2018 | BioXFEL Publications | Contributor(s): Max Rose, Sergey Bobkov, Kartik Ayyer, Ruslan P. Kurta, Dmitry Dzhigaev, Young Yong Kim, Andrew J. Morgan, Chun Hong Yoon, Daniel Westphal, Johan Bielecki, Jonas A. Sellberg, Garth Williams, Filipe R.N.C. Maia, Olexander M. Yefanov, Vyacheslav Ilyin, Adrian P. Mancuso, Henry Chapman, Brenda Hogue, Andrew Aquila, Anton Barty, Ivan A. Vartanyants

    http://dx.doi.org/10.1107/s205225251801120x/it5017sup9.mp4 component Rose, M. et al., 2018. Single-particle imaging without symmetry constraints at an X-ray free-electron laser. Available at: http://dx.doi.org/10.1107/s205225251801120x/it5017sup9.mp4. Max Rose and Sergey Bobkov and Kartik Ayyer …

  19. Single-particle structure determination by X-ray free-electron lasers: Possibilities and challenges

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    30 Apr 2015 | BioXFEL Publications | Contributor(s): A. Hosseinizadeh, A. Dashti, P. Schwander, R. Fung, A. Ourmazd

    http://dx.doi.org/10.1063/1.4919740 A. Hosseinizadeh and A. Dashti and P. Schwander and R. Fung and A. Ourmazd Hosseinizadeh, A. et al., 2015. Single-particle structure determination by X-ray free-electron lasers: Possibilities and challenges. Structural Dynamics, 2(4), p.041601. Available at: …

  20. Single-shot determination of focused FEL wave fields using iterative phase retrieval

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    18 Jul 2017 | BioXFEL Publications | Contributor(s): Masoud Mehrjoo, Klaus Giewekemeyer, Patrik Vagovič, Stephan Stern, Richard Bean, Marc Messerschmidt, Barbara Keitel, Elke Plönjes, Marion Kuhlmann, Tobias Mey, Evgeny A. Schneidmiller, Mikhail V. Yurkov, Torsten Limberg, Adrian P. Mancuso

    http://dx.doi.org/10.1364/oe.25.017892 journal-article Mehrjoo, M. et al., 2017. Single-shot determination of focused FEL wave fields using iterative phase retrieval. Optics Express, 25(15), p.17892. Available at: http://dx.doi.org/10.1364/oe.25.017892. Masoud Mehrjoo and Klaus Giewekemeyer and …

  21. Single-shot diffraction data from the Mimivirus particle using an X-ray free-electron laser

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    29 Jul 2016 | BioXFEL Publications | Contributor(s): Tomas Ekeberg, Martin Svenda, M. Marvin Seibert, Chantal Abergel, Filipe R.N.C. Maia, Virginie Seltzer, Daniel P. DePonte, Andrew Aquila, Jakob Andreasson, Bianca Iwan, Olof Jönsson, Daniel Westphal, Duško Odić, Inger Andersson, Anton Barty, Meng Liang, Andrew V. Martin, Lars Gumprecht, Holger Fleckenstein, Saša Bajt, Miriam Barthelmess, Nicola Coppola, Jean-Michel Claverie, N. Duane Loh, Christoph Bostedt, John D. Bozek, Jacek Krzywinski, Marc Messerschmidt, Michael J. Bogan, Christina Y. Hampton, Raymond G. Sierra, Matthias Frank, Robert L. Shoeman, Lukas Lomb, Lutz Foucar, Sascha W. Epp, Daniel Rolles, Artem Rudenko, Robert Hartmann, Andreas Hartmann, Nils Kimmel, Peter Holl, Georg Weidenspointner, Benedikt Rudek, Benjamin Erk, Stephan Kassemeyer, Ilme Schlichting, Lothar Strüder, Joachim Ullrich, Carlo Schmidt, Faton Krasniqi, Günter Hauser, Christian Reich, Heike Soltau, Sebastian Schorb, Helmut Hirsemann, Cornelia Wunderer, Heinz Graafsma, Henry Chapman, Janos Hajdu

    http://dx.doi.org/10.1038/sdata.2016.60 Tomas Ekeberg and Martin Svenda and M. Marvin Seibert and Chantal Abergel and Filipe R.N.C. Maia and Virginie Seltzer and Daniel P. DePonte and Andrew Aquila and Jakob Andreasson and Bianca Iwan and Olof Jönsson and Daniel Westphal and Duško Odić and Inger …

  22. Single-Walled Carbon Nanotubes Probed with Insulator-Based Dielectrophoresis

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    13 Nov 2017 | BioXFEL Publications | Contributor(s): Mohammad Towshif Rabbani, Christoph F. Schmidt, Alexandra Ros

    http://dx.doi.org/10.1021/acs.analchem.7b03105 journal-article Rabbani, M.T., Schmidt, C.F. & Ros, A., 2017. Single-Walled Carbon Nanotubes Probed with Insulator-Based Dielectrophoresis. Analytical Chemistry, 89(24), pp.13235–13244. Available at: http://dx.doi.org/10.1021/acs.analchem.7b03105. …

  23. Six-Helix Bundle and Triangle DNA Origami Insulator-Based Dielectrophoresis

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    24 Oct 2013 | BioXFEL Publications | Contributor(s): Lin Gan, Tzu-Chiao Chao, Fernanda Camacho-Alanis, Alexandra Ros

    http://dx.doi.org/10.1021/ac402493u journal-article Gan, L. et al., 2013. Six-Helix Bundle and Triangle DNA Origami Insulator-Based Dielectrophoresis. Analytical Chemistry, 85(23), pp.11427–11434. Available at: http://dx.doi.org/10.1021/ac402493u. Lin Gan and Tzu-Chiao Chao and Fernanda …

  24. Small Angle X-Ray Scattering as a Complementary Tool for High-Throughput Structural Studies

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    21 May 2014 | Publications | Contributor(s): Tom Grant, Edward Snell

    Structural crystallography and nuclear magnetic resonance (NMR) spectroscopy are the predominant techniques for understanding the biological world on a molecular level. Crystallography is constrained by the ability to form a crystal that diffracts well and NMR is constrained to smaller proteins. …

  25. Small Is Beautiful: Growth and Detection of Nanocrystals

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    27 Dec 2018 | BioXFEL Publications | Contributor(s): Jesse David Coe, Alexandra Ros

    http://dx.doi.org/10.1007/978-3-030-00551-1_3 book-chapter Coe, J. & Ros, A., 2018. Small Is Beautiful: Growth and Detection of Nanocrystals. X-ray Free Electron Lasers, pp.59–85. Available at: http://dx.doi.org/10.1007/978-3-030-00551-1_3. Jesse Coe and Alexandra Ros

  26. Small-angle X-ray and neutron scattering demonstrates that cell-free expression produces properly formed disc-shaped nanolipoprotein particles

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    20 Dec 2017 | BioXFEL Publications | Contributor(s): Thomas E. Cleveland, Wei He, Angela C. Evans, Nicholas O. Fischer, Edmond Y. Lau, Matthew Coleman, Paul Butler

    http://dx.doi.org/10.1002/pro.3365 journal-article Cleveland, T.E. et al., 2017. Small-angle X-ray and neutron scattering demonstrates that cell-free expression produces properly formed disc-shaped nanolipoprotein particles. Protein Science. Available at: http://dx.doi.org/10.1002/pro.3365. …

  27. Sodium Binding in Cysteinyl Leukotriene G Protein-Coupled Receptors

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    12 Feb 2021 | BioXFEL Publications | Contributor(s): Viktoriia Shaulskaia, Aleksandra Luginina, Polina Khorn, Anastasiia Gusach, Olga Sukhacheva, Ekaterina Smirnova, Valentin Borshchevskiy, Alexey Mishin, Vadim Cherezov

    http://dx.doi.org/10.1016/j.bpj.2020.11.987 journal-article Shaulskaia, V. et al., 2021. Sodium Binding in Cysteinyl Leukotriene G Protein-Coupled Receptors. Biophysical Journal, 120(3), p.129a. Available at: http://dx.doi.org/10.1016/j.bpj.2020.11.987. Viktoriia Shaulskaia and Aleksandra …

  28. Soft x-ray free-electron laser induced damage to inorganic scintillators

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    07 Jan 2015 | BioXFEL Publications | Contributor(s): Tomáš Burian, Věra Hájková, Jaromír Chalupský, Luděk Vyšín, Pavel Boháček, Martin Přeček, Jan Wild, Cigdem Özkan, Nicola Coppola, Shafagh Dastjani Farahani, Joachim Schulz, Harald Sinn, Thomas Tschentscher, Jérôme Gaudin, Saša Bajt, Kai Tiedtke, Sven Toleikis, Henry Chapman, Rolf A. Loch, Marek Jurek, Ryszard Sobierajski, Jacek Krzywinski, Stefan Moeller, Marion Harmand, Germano Galasso, Mitsuru Nagasono, Karel Saskl, Pavol Sovák, Libor Juha

    http://dx.doi.org/10.1364/ome.5.000254 Tomáš Burian and Věra Hájková and Jaromír Chalupský and Luděk Vyšín and Pavel Boháček and Martin Přeček and Jan Wild and Cigdem Özkan and Nicola Coppola and Shafagh Dastjani Farahani and Joachim Schulz and Harald Sinn and Thomas Tschentscher and …

  29. Solution and Crystal Structures of a Sperm Whale Myoglobin Triple Mutant That Mimics the Sulfide-binding Hemoglobin fromLucina pectinata

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    26 Jul 2002 | BioXFEL Publications | Contributor(s): Bao D. Nguyen, Xuefeng Zhao, Krishnamurthi Vyas, Gerd N. La Mar, R. Ashley Lile, Eric Allen Brucker, George Phillips, John S. Olson, Jonathan B. Wittenberg

    http://dx.doi.org/10.1074/jbc.273.16.9517 journal-article Nguyen, B.D. et al., 1998. Solution and Crystal Structures of a Sperm Whale Myoglobin Triple Mutant That Mimics the Sulfide-binding Hemoglobin fromLucina pectinata. Journal of Biological Chemistry, 273(16), pp.9517–9526. Available at: …

  30. Solution structure(s) of trinucleosomes from contrast variation SAXS

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    12 Apr 2021 | BioXFEL Publications | Contributor(s): Alexander W Mauney, Uma M Muthurajan, Karolin Luger, Lois Pollack

    http://dx.doi.org/10.1093/nar/gkab290 Abstract Nucleosomes in all eukaryotic cells are organized into higher order structures that facilitate genome compaction. Visualizing these organized structures is an important step in understanding how genomic DNA is efficiently stored yet …

  31. Solution to the phase problem for surface X-ray diffraction

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    14 Mar 2015 | BioXFEL Publications | Contributor(s): P.F. Lyman, V.L. Shneerson, R. Fung, R.J. Harder, S.S. Parihar, H.T. Johnson-Steigelman, D.K. Saldin

    http://dx.doi.org/10.1107/s0108767308096505 journal-article Lyman, P.F. et al., 2008. Solution to the phase problem for surface X-ray diffraction. Acta Crystallographica Section A Foundations of Crystallography, 64(a1), pp.C109–C109. Available at: http://dx.doi.org/10.1107/s0108767308096505. …

  32. Solving protein nanocrystals by cryo-EM diffraction: Multiple scattering artifacts

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    07 Oct 2014 | BioXFEL Publications | Contributor(s): GANESH SUBRAMANIAN, Shibom Basu, Haiguang Liu, Jian-Min Zuo, John Spence

    http://dx.doi.org/10.1016/j.ultramic.2014.08.013 Ganesh Subramanian and Shibom Basu and Haiguang Liu and Jian-Min Zuo and John C.H. Spence Subramanian, G. et al., 2015. Solving protein nanocrystals by cryo-EM diffraction: Multiple scattering artifacts. Ultramicroscopy, 148, pp.87–93. Available …

  33. Solving protein structure from sparse serial microcrystal diffraction data at a storage-ring synchrotron source

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    20 Jul 2018 | BioXFEL Publications | Contributor(s): Ti-Yen Lan, Jennifer L. Wierman, Mark W. Tate, Hugh T. Philipp, Jose M. Martin-Garcia, Lan Zhu, David Kissick, Petra Fromme, Robert F. Fischetti, Wei Liu, Veit Elser, Sol M. Gruner

    http://dx.doi.org/10.1107/s205225251800903x In recent years, the success of serial femtosecond crystallography and the paucity of beamtime at X-ray free-electron lasers have motivated the development of serial microcrystallography experiments at storage-ring synchrotron sources. However, especially …

  34. Spatial characterization of FLASH2 pulses: current status and future plan (Conference Presentation)

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    14 May 2019 | BioXFEL Publications | Contributor(s): Masoud Mehrjoo, Elke Plönjes, Barbara Keitel, Marion Kuhlmann, Mabel Ruiz-Lopez, Thomas Wodzinski, Klaus Giewekemeyer, Patrik Vagovic, Yoonhee Kim, Mohammadreza Banjafar, Marc Messerschmidt, Tomáš Burian

    http://dx.doi.org/10.1117/12.2523254 proceedings-article Mehrjoo, M. et al., 2019. Spatial characterization of FLASH2 pulses: current status and future plan (Conference Presentation) T. Tschentscher et al., eds. X-Ray Free-Electron Lasers: Advances in Source Development and Instrumentation V. …

  35. Spatiotemporal Pattern Extraction by Spectral Analysis of Vector-Valued Observables

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    13 May 2019 | BioXFEL Publications | Contributor(s): Dimitrios Giannakis, Abbas Ourmazd, Joanna Slawinska, Zhizhen Zhao

    http://dx.doi.org/10.1007/s00332-019-09548-1 journal-article Giannakis, D. et al., 2019. Spatiotemporal Pattern Extraction by Spectral Analysis of Vector-Valued Observables. Journal of Nonlinear Science. Available at: http://dx.doi.org/10.1007/s00332-019-09548-1. Dimitrios Giannakis and Abbas …

  36. Special issue on imaging the dynamic structure of matter

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    30 Jun 2016 | BioXFEL Publications | Contributor(s): Heinrich Schwoerer, Henry Chapman, Bradley J Siwick, R J Dwayne Miller

    http://dx.doi.org/10.1088/0953-4075/49/15/150201 journal-article Schwoerer, H. et al., 2016. Special issue on imaging the dynamic structure of matter. Journal of Physics B: Atomic, Molecular and Optical Physics, 49(15), p.150201. Available at: http://dx.doi.org/10.1088/0953-4075/49/15/150201. …

  37. Spectral encoding method for measuring the relative arrival time between x-ray/optical pulses

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    28 Aug 2014 | BioXFEL Publications | Contributor(s): M. R. Bionta, N. Hartmann, M. Weaver, D. French, D. J. Nicholson, J. P. Cryan, J. M. Glownia, K. Baker, C. Bostedt, M. Chollet, Y. Ding, D. M. Fritz, A. R. Fry, D. J. Kane, J. Krzywinski, H. T. Lemke, M. Messerschmidt, S. Schorb, D. Zhu, W. E. White, R. N. Coffee

    journal-article http://dx.doi.org/10.1063/1.4893657 Bionta, M.R. et al., 2014. Spectral encoding method for measuring the relative arrival time between x-ray/optical pulses. Review of Scientific Instruments, 85(8), p.083116. Available at: http://dx.doi.org/10.1063/1.4893657. M. R. Bionta and N. …

  38. Spectral Hole Burning in Cyanobacterial Photosystem I with P700 in Oxidized and Neutral States

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    23 Sep 2016 | BioXFEL Publications | Contributor(s): Nicoleta Herascu, Mark S. Hunter, Golia Shafiei, Mehdi Najafi, T. Wade Johnson, Petra Fromme, Valter Zazubovich

    http://dx.doi.org/10.1021/acs.jpcb.6b07803 Nicoleta Herascu and Mark S. Hunter and Golia Shafiei and Mehdi Najafi and T. Wade Johnson and Petra Fromme and Valter Zazubovich Herascu, N. et al., 2016. Spectral Hole Burning in Cyanobacterial Photosystem I with P700 in Oxidized and Neutral States. The …

  39. Spectroscopic Studies of Model Photo-Receptors: Validation of a Nanosecond Time-Resolved Micro-Spectrophotometer Design Using Photoactive Yellow Protein and α-Phycoerythrocyanin

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    16 Sep 2013 | BioXFEL Publications | Contributor(s): Namrta Purwar, Jason Tenboer, Shailesh Tripathi, Marius Schmidt

    http://dx.doi.org/10.3390/ijms140918881 journal-article Purwar, N. et al., 2013. Spectroscopic Studies of Model Photo-Receptors: Validation of a Nanosecond Time-Resolved Micro-Spectrophotometer Design Using Photoactive Yellow Protein and α-Phycoerythrocyanin. International Journal of Molecular …

  40. Spermine Condenses DNA, but Not RNA Duplexes

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    10 Jan 2017 | BioXFEL Publications | Contributor(s): Andrea Katz, Igor S. Tolokh, Suzette A. Pabit, Nathan Baker, Alexey V. Onufriev, Lois Pollack

    http://dx.doi.org/10.1016/j.bpj.2016.11.018 journal-article Katz, A.M. et al., 2017. Spermine Condenses DNA, but Not RNA Duplexes. Biophysical Journal, 112(1), pp.22–30. Available at: http://dx.doi.org/10.1016/j.bpj.2016.11.018. Andrea M. Katz and Igor S. Tolokh and Suzette A. Pabit and Nathan …

  41. SPIND: a reference-based auto-indexing algorithm for sparse serial crystallography data

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    10 Dec 2018 | BioXFEL Publications | Contributor(s): Chufeng Li, Xuanxuan Li, Richard Kirian, John Spence, Haiguang Liu, Nadia Zatsepin

    http://dx.doi.org/10.1107/s2052252518014951 SPIND (sparse-pattern indexing) is an auto-indexing algorithm for sparse snapshot diffraction patterns (`stills') that requires the positions of only five Bragg peaks in a single pattern, when provided with unit-cell parameters. The …

  42. Split-Second Reactions

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    24 Apr 2017 | BioXFEL Publications | Contributor(s): Petra Fromme, John Spence

    http://dx.doi.org/10.1038/scientificamerican0517-62 journal-article Fromme, P. & Spence, J.C.H., 2017. Split-Second Reactions. Scientific American, 316(5), pp.62–67. Available at: http://dx.doi.org/10.1038/scientificamerican0517-62. Petra Fromme and John C. H. Spence

  43. Stable Chromosome Condensation Revealed by Chromosome Conformation Capture

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    05 Nov 2015 | BioXFEL Publications | Contributor(s): Kyle P. Eagen, Tom A. Hartl, Roger D. Kornberg

    journal-article http://dx.doi.org/10.1016/j.cell.2015.10.026 Eagen, K.P., Hartl, T.A. & Kornberg, R.D., 2015. Stable Chromosome Condensation Revealed by Chromosome Conformation Capture. Cell, 163(4), pp.934–946. Available at: http://dx.doi.org/10.1016/j.cell.2015.10.026. Kyle P. Eagen and …

  44. State of the structure address on MET receptor activation by HGF

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    17 Apr 2021 | BioXFEL Publications | Contributor(s): Edmond M. Linossi, Gabriella O. Estevam, Masaya Oshima, James Fraser, Eric A. Collisson, Natalia Jura

    http://dx.doi.org/10.1042/bst20200394 The MET receptor tyrosine kinase (RTK) and its cognate ligand hepatocyte growth factor (HGF) comprise a signaling axis essential for development, wound healing and tissue homeostasis. Aberrant HGF/MET signaling is a driver of many cancers and contributes to …

  45. Statistical Analysis of Crystallization Database Links Protein Physico-Chemical Features with Crystallization Mechanisms

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    02 Jul 2014 | BioXFEL Publications | Contributor(s): Diana Fusco, Timothy J. Barnum, Andrew E. Bruno, Joseph Luft, Edward Snell, Sayan Mukherjee, Patrick Charbonneau

    http://dx.doi.org/10.1371/journal.pone.0101123 journal-article Fusco, D. et al., 2014. Statistical Analysis of Crystallization Database Links Protein Physico-Chemical Features with Crystallization Mechanisms B. Kobe, ed. PLoS ONE, 9(7), p.e101123. Available at: …

  46. Strategies to sample crystallization space

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    14 Oct 2015 | Teaching Materials | Contributor(s): Joseph Luft

    Joe Luft discusses crystallization screening strategies to maximize the likelihood of success.

  47. stream2stats

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    01 Apr 2015 | Downloads | Contributor(s): Tom Grant

    'stream2stats' makes quick work of calculating a variety of merging statistics from SFX data and plotting them

  48. Strongly aligned gas-phase molecules at free-electron lasers

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    17 Sep 2015 | BioXFEL Publications | Contributor(s): Thomas Kierspel, Joss Wiese, Terry Mullins, Joseph Robinson, Andy Aquila, Anton Barty, Richard Bean, Rebecca Boll, Sébastien Boutet, Philip Bucksbaum, Henry Chapman, Lauge Christensen, Alan Fry, Mark S. Hunter, Jason E Koglin, Mengning Liang, Valerio Mariani, Andrew Morgan, Adi Natan, Vladimir Petrovic, Daniel Rolles, Artem Rudenko, Kirsten Schnorr, Henrik Stapelfeldt, Stephan Stern, Jan Thøgersen, Chun Hong Yoon, Fenglin Wang, Sebastian Trippel, Jochen Küpper

    http://dx.doi.org/10.1088/0953-4075/48/20/204002 Thomas Kierspel and Joss Wiese and Terry Mullins and Joseph Robinson and Andy Aquila and Anton Barty and Richard Bean and Rebecca Boll and Sébastien Boutet and Philip Bucksbaum and Henry N Chapman and Lauge Christensen and Alan Fry and Mark Hunter …

  49. Structural adaptation of oxygen tolerance in 4-hydroxybutyrl-CoA dehydratase, a key enzyme of archaeal carbon fixation

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    07 Feb 2020 | BioXFEL Publications | Contributor(s): Hasan Demirci, Bradley B. Tolar, Tzanko Doukov, Aldis Petriceks, Akshaye Pal, Yasuo Yoshikuni, Aharon Gomez, David A. Saez, Esteban Vöhringer-Martinez, Thomas Schwander, Tobias J. Erb, Christopher A. Francis, Soichi Wakatsuki

    http://dx.doi.org/10.1101/2020.02.05.935528 AbstractAutotrophic microorganisms that convert inorganic carbon into organic matter were key players in the evolution of life on Earth. As the early atmosphere became oxygenated, microorganisms needed to develop mechanisms for oxygen protection, …

  50. Structural analysis of wild-type and Val120Thr mutant Candida boidinii formate dehydrogenase by X-ray crystallography

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    20 Oct 2023 | BioXFEL Publications | Contributor(s): Mehmet Gul, Busra Yuksel, Huri Bulut, Hasan Demirci

    http://dx.doi.org/10.1107/s2059798323008070 Candida boidinii NAD+-dependent formate dehydrogenase (CbFDH) has gained significant attention for its potential application in the production of biofuels and various industrial chemicals from inorganic carbon dioxide. The present study …

  51. Structural and biophysical properties of FopA, a major outer membrane protein of Francisella tularensis

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    01 Aug 2022 | BioXFEL Publications | Contributor(s): Nirupa Nagaratnam, Jose M. Martin-Garcia, Jay-How Yang, Matthew R. Goode, Gihan Kaushylal Ketawala, Felicia M. Craciunescu, James D Zook, Manashi Sonowal, Dewight Williams, Thomas D. Grant, Raimund Fromme, Debra T. Hansen, Petra Fromme

    http://dx.doi.org/10.1371/journal.pone.0267370 Francisella tularensis is an extremely infectious pathogen and a category A bioterrorism agent. It causes the highly contagious zoonosis, Tularemia. Currently, FDA approved vaccines against tularemia are unavailable. F. tularensis outer membrane …

  52. Structural and evolutionary relationships of ketosynthase domains from modular polyketide synthases

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    25 Jun 2015 | BioXFEL Publications | Contributor(s): JR Lohman, A Joachimiak, GN Phillips Jr, B Shen

    journal-article http://dx.doi.org/10.1055/s-0035-1556231 Lohman, J. et al., 2015. Structural and evolutionary relationships of ketosynthase domains from modular polyketide synthases. Planta Medica, 81(11). Available at: http://dx.doi.org/10.1055/s-0035-1556231. JR Lohman and A Joachimiak and GN …

  53. Structural and evolutionary relationships of “AT-less” type I polyketide synthase ketosynthases

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    29 Sep 2015 | BioXFEL Publications | Contributor(s): Jeremy R. Lohman, Ming Ma, Jerzy Osipiuk, Boguslaw Nocek, Youngchang Kim, Changsoo Chang, Marianne Cuff, Jamey Mack, Lance Bigelow, Hui Li, Michael Endres, Gyorgy Babnigg, Andrzej Joachimiak, George Phillips, Ben Shen

    http://dx.doi.org/10.1073/pnas.1515460112 Jeremy R. Lohman and Ming Ma and Jerzy Osipiuk and Boguslaw Nocek and Youngchang Kim and Changsoo Chang and Marianne Cuff and Jamey Mack and Lance Bigelow and Hui Li and Michael Endres and Gyorgy Babnigg and Andrzej Joachimiak and George N. Phillips and Ben …

  54. Structural basis for bifunctional peptide recognition at human δ-opioid receptor

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    16 Feb 2015 | BioXFEL Publications | Contributor(s): Gustavo Fenalti, Nadia Zatsepin, Cecilia Betti, Patrick Giguere, Gye Won Han, Andrii Ishchenko, Wei Liu, Karel Guillemyn, Haitao Zhang, Daniel James, Dingjie Wang, Uwe Weierstall, John Spence, Sébastien Boutet, Marc Messerschmidt, Garth J Williams, Cornelius Gati, Oleksandr M Yefanov, Thomas A White, Dominik Oberthuer, Markus Metz, Chun Hong Yoon, Anton Barty, Henry Chapman, Shibom Basu, Jesse David Coe, Chelsie E Conrad, Raimund Fromme, Petra Fromme, Dirk Tourwé, Peter W Schiller, Bryan L Roth, Steven Ballet, Vsevolod Katritch, Raymond C Stevens, Vadim Cherezov

    http://dx.doi.org/10.1038/nsmb.2965 Gustavo Fenalti and Nadia A Zatsepin and Cecilia Betti and Patrick Giguere and Gye Won Han and Andrii Ishchenko and Wei Liu and Karel Guillemyn and Haitao Zhang and Daniel James and Dingjie Wang and Uwe Weierstall and John C H Spence and Sébastien Boutet and …

  55. Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics

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    14 Feb 2022 | BioXFEL Publications | Contributor(s): Kaitlyn Tsai, Vanja Stojković, D. John Lee, Iris Diane Young, Teresa Szal, Dorota Klepacki, Nora Vázquez-Laslop, Alexander S. Mankin, James Fraser, Danica Galonić Fujimori

    http://dx.doi.org/10.1038/s41594-022-00723-9 journal-article Tsai, K., Stojković, V., Lee, D. J., Young, I. D., Szal, T., Klepacki, D., Vázquez-Laslop, N., Mankin, A. S., Fraser, J. S., & Fujimori, D. G. (2022). Structural basis for context-specific inhibition of translation by oxazolidinone …

  56. Structural Basis for Ligand Recognition and Functional Selectivity at Angiotensin Receptor

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    29 Sep 2015 | BioXFEL Publications | Contributor(s): Haitao Zhang, Hamiyet Unal, Russell Desnoyer, Gye Won Han, Nilkanth N Patel, Vsevolod Katritch, Sadashiva S. Karnik, Vadim Cherezov, Raymond C. Stevens

    http://dx.doi.org/10.1074/jbc.m115.689000 Haitao Zhang and Hamiyet Unal and Russell Desnoyer and Gye Won Han and Nilkanth Patel and Vsevolod Katritch and Sadashiva S. Karnik and Vadim Cherezov and Raymond C. Stevens Zhang, H. et al., 2015. Structural Basis for Ligand Recognition and Functional …

  57. Structural basis for light control of cell development revealed by crystal structures of a myxobacterial phytochrome

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    29 Aug 2018 | BioXFEL Publications | Contributor(s): Nicole C. Woitowich, Andrei S. Halavaty, Patricia Waltz, Christopher Kupitz, Joseph Valera, Gregory Tracy, Kevin D. Gallagher, Elin Claesson, Takanori Nakane, Suraj Pandey, Garrett Charles Nelson, Rie Tanaka, Eriko Nango, Eiichi Mizohata, Shigeki Owada, Kensure Tono, Yasumasa Joti, Angela C. Nugent, Hardik Patel, Ayesha Mapara, James Hopkins, Phu Duong, Dorina Bizhga, Svetlana E. Kovaleva, Rachael St. Peter, Cynthia N. Hernandez, Wesley B. Ozarowski, Shatabdi Roy-Chowdhuri, Jay-How Yang, Petra Edlund, Heikki Takala, Janne Ihalainen, Jennifer Brayshaw, Tyler Norwood, Ishwor Poudyal, Petra Fromme, John Spence, Keith Moffat, Sebastian Westenhoff, Marius Schmidt, Emina A. Stojković

    http://dx.doi.org/10.1107/s2052252518010631 Phytochromes are red-light photoreceptors that were first characterized in plants, with homologs in photosynthetic and non-photosynthetic bacteria known as bacteriophytochromes (BphPs). Upon absorption of light, BphPs interconvert between two states …

  58. Structural basis for receptor selectivity and inverse agonism in S1P5 receptors

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    12 Aug 2022 | BioXFEL Publications | Contributor(s): Elizaveta Lyapina, Egor Marin, Anastasiia Gusach, Philipp Orekhov, Andrey Gerasimov, Aleksandra Luginina, Daniil Vakhrameev, Margarita Ergasheva, Margarita Kovaleva, Georgii Khusainov, Polina Khorn, Mikhail Shevtsov, Kirill Kovalev, Sergey Bukhdruker, Ivan Okhrimenko, Petr Popov, Hao Hu, Uwe Weierstall, Wei Liu, Yunje Cho, Ivan Gushchin, Andrey Rogachev, Gleb Bourenkov, Sehan Park, Gisu Park, Hyo Jung Hyun, Jaehyun Park, Valentin Gordeliy, Valentin Borshchevskiy, Alexey Mishin, Vadim Cherezov

    http://dx.doi.org/10.1038/s41467-022-32447-1 AbstractThe bioactive lysophospholipid sphingosine-1-phosphate (S1P) acts via five different subtypes of S1P receptors (S1PRs) - S1P1-5. S1P5 is predominantly expressed in nervous and immune systems, regulating the egress of natural killer cells from …

  59. Structural basis for selectivity and diversity in angiotensin II receptors

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    04 Apr 2017 | BioXFEL Publications | Contributor(s): Haitao Zhang, Gye Won Han, Alexander Batyuk, Andrii Ishchenko, Kate L. White, Nilkanth N Patel, Anastasiia Sadybekov, Beata Zamlynny, Michael T. Rudd, Kaspar Hollenstein, Alexandra Tolstikova, Thomas A. White, Mark S. Hunter, Uwe Weierstall, Wei Liu, Kerim Babaoglu, Eric L. Moore, Ryan D. Katz, Jennifer M. Shipman, Margarita Garcia-Calvo, Sujata Sharma, Payal Sheth, Stephen M. Soisson, Raymond C. Stevens, Vsevolod Katritch, Vadim Cherezov

    http://dx.doi.org/10.1038/nature22035 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Zhang, H. et al., 2017. Structural basis for selectivity and diversity in angiotensin II receptors. Nature, 544(7650), pp.327–332. Available at: http://dx.doi.org/10.1038/nature22035. Haitao …

  60. Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases

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    29 May 2015 | BioXFEL Publications | Contributor(s): Fengbin Wang, Shanteri Singh, Weijun Xu, Kate E. Helmich, Mitchell Miller, Hongnan Cao, Craig A. Bingman, Jon S. Thorson, George Phillips

    http://dx.doi.org/10.1021/acschembio.5b00244 Fengbin Wang and Shanteri Singh and Weijun Xu and Kate E. Helmich and Mitchell D. Miller and Hongnan Cao and Craig A. Bingman and Jon S. Thorson and George N. Phillips Wang, F. et al., 2015. Structural Basis for the Stereochemical Control of Amine …

  61. Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile α Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors

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    04 Jun 2015 | BioXFEL Publications | Contributor(s): Ying Wu, Leonardus M. I. Koharudin, Jennifer Mehrens, Maria DeLucia, Chang-Hyeok Byeon, In-Ja L. Byeon, Guillermo Calero, Jinwoo Ahn, Angela M. Gronenborn

    journal-article http://dx.doi.org/10.1074/jbc.m115.665513 Wu, Y. et al., 2015. Structural Basis of Clade-specific Engagement of SAMHD1 (Sterile α Motif and Histidine/Aspartate-containing Protein 1) Restriction Factors by Lentiviral Viral Protein X (Vpx) Virulence Factors. Journal of Biological …

  62. Structural basis of ligand recognition at the human MT1 melatonin receptor

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    24 Apr 2019 | BioXFEL Publications | Contributor(s): Benjamin Stauch, Linda C. Johansson, John D. McCorvy, Nilkanth N Patel, Gye Won Han, Xi-Ping Huang, Cornelius Gati, Alexander Batyuk, Samuel T. Slocum, Andrii Ishchenko, Wolfgang Brehm, Thomas A. White, Nairie Michaelian, Caleb Alexander Madsen, Lan Zhu, Thomas D. Grant, Jessica M. Grandner, Anna Shiriaeva, Reid H. J. Olsen, Alexandra R. Tribo, Saïd Yous, Raymond C. Stevens, Uwe Weierstall, Vsevolod Katritch, Bryan L. Roth, Wei Liu, Vadim Cherezov

    http://dx.doi.org/10.1038/s41586-019-1141-3 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Stauch, B. et al., 2019. Structural basis of ligand recognition at the human MT1 melatonin receptor. Nature. Available at: http://dx.doi.org/10.1038/s41586-019-1141-3. Benjamin Stauch and …

  63. Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors

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    06 Dec 2019 | BioXFEL Publications | Contributor(s): Anastasiia Gusach, Aleksandra Luginina, Egor Marin, Rebecca L. Brouillette, Élie Besserer-Offroy, Jean-Michel Longpré, Andrii Ishchenko, Petr Popov, Nilkanth N Patel, Taku Fujimoto, Toru Maruyama, Benjamin Stauch, Margarita Ergasheva, Daria Romanovskaia, Anastasiia Stepko, Kirill Kovalev, Mikhail Shevtsov, Valentin Gordeliy, Gye Won Han, Vsevolod Katritch, Valentin Borshchevskiy, Philippe Sarret, Alexey Mishin, Vadim Cherezov

    http://dx.doi.org/10.1038/s41467-019-13348-2 journal-article Gusach, A. et al., 2019. Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors. Nature Communications, 10(1). Available at: http://dx.doi.org/10.1038/s41467-019-13348-2. Anastasiia Gusach and …

  64. Structural Basis of Stereospecificity in the Bacterial Enzymatic Cleavage of β-Aryl Ether Bonds in Lignin

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    04 Dec 2015 | BioXFEL Publications | Contributor(s): Kate E. Helmich, Jose Henrique Pereira, Daniel L. Gall, Richard A. Heins, Ryan P. McAndrew, Craig Bingman, Kai Deng, Keefe C. Holland, Daniel R. Noguera, Blake A. Simmons, Kenneth L. Sale, John Ralph, Timothy J. Donohue, Paul D. Adams, George Phillips

    http://dx.doi.org/10.1074/jbc.m115.694307 Kate E. Helmich and Jose Henrique Pereira and Daniel L. Gall and Richard A. Heins and Ryan P. McAndrew and Craig Bingman and Kai Deng and Keefe C. Holland and Daniel R. Noguera and Blake A. Simmons and Kenneth L. Sale and John Ralph and Timothy J. Donohue …

  65. Structural biology in the time of COVID-19: perspectives on methods and milestones

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    22 Apr 2021 | BioXFEL Publications | Contributor(s): Miranda Lynch, Edward Snell, Sarah EJ Bowman

    http://dx.doi.org/10.1107/s2052252521003948 The global COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has wreaked unprecedented havoc on global society, in terms of a huge loss of life and burden of morbidity, economic upheaval and social disruption. Yet …

  66. Structural biology is solved — now what?

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    11 Jan 2022 | BioXFEL Publications | Contributor(s): Abbas Ourmazd, Keith Moffat, Eaton E Lattman

    http://dx.doi.org/10.1038/s41592-021-01357-3 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Ourmazd, A., Moffat, K., & Lattman, E. E. (2022). Structural biology is solved — now what? Nature Methods, 19(1), 24–26. https://doi.org/10.1038/s41592-021-01357-3 Abbas Ourmazd and …

  67. Structural biology of G protein-coupled receptors: new opportunities from XFELs and cryoEM

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    16 Mar 2018 | BioXFEL Publications | Contributor(s): Andrii Ishchenko, Cornelius Gati, Vadim Cherezov

    http://dx.doi.org/10.1016/j.sbi.2018.03.009 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Ishchenko, A., Gati, C. & Cherezov, V., 2018. Structural biology of G protein-coupled receptors: new opportunities from XFELs and cryoEM. Current Opinion in Structural Biology, 51, …

  68. Structural changes of tailless bacteriophage ΦX174 during penetration of bacterial cell walls

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    11 Dec 2017 | BioXFEL Publications | Contributor(s): Yingyuan Sun, Aaron P. Roznowski, Joshua M. Tokuda, Thomas Klose, Alexander Mauney, Lois Pollack, Bentley A. Fane, Michael G. Rossmann

    http://dx.doi.org/10.1073/pnas.1716614114 journal-article Sun, Y. et al., 2017. Structural changes of tailless bacteriophage ΦX174 during penetration of bacterial cell walls. Proceedings of the National Academy of Sciences, p.201716614. Available at: http://dx.doi.org/10.1073/pnas.1716614114. …

  69. Structural characterization of AtmS13, a putative sugar aminotransferase involved in indolocarbazole AT2433 aminopentose biosynthesis

    0.0 out of 5 stars 

    10 Jun 2015 | BioXFEL Publications | Contributor(s): Shanteri Singh, Youngchang Kim, Fengbin Wang, Lance Bigelow, Michael Endres, Madan K. Kharel, Gyorgy Babnigg, Craig A. Bingman, Andrzej Joachimiak, Jon S. Thorson, George Phillips

    http://dx.doi.org/10.1002/prot.24844 Shanteri Singh and Youngchang Kim and Fengbin Wang and Lance Bigelow and Michael Endres and Madan K. Kharel and Gyorgy Babnigg and Craig A. Bingman and Andrzej Joachimiak and Jon S. Thorson and George N. Phillips Singh, S. et al., 2015. Structural …

  70. Structural Characterization of CalS8, a TDP-α-d-Glucose Dehydrogenase Involved in Calicheamicin Aminodideoxypentose Biosynthesis

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    03 Aug 2015 | BioXFEL Publications | Contributor(s): Shanteri Singh, Karolina Michalska, Lance Bigelow, Michael Endres, Madan K. Kharel, Gyorgy Babnigg, Ragothaman M. Yennamalli, Craig A. Bingman, Andrzej Joachimiak, Jon S. Thorson, George Phillips

    http://dx.doi.org/10.1074/jbc.m115.673459 Shanteri Singh and Karolina Michalska and Lance Bigelow and Michael Endres and Madan K. Kharel and Gyorgy Babnigg and Ragothaman M. Yennamalli and Craig A. Bingman and Andrzej Joachimiak and Jon S. Thorson and George N. Phillips Singh, S. et al., 2015. …

  71. Structural dynamics of a methionine γ-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate

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    29 Apr 2016 | BioXFEL Publications | Contributor(s): Hongnan Cao, Kemin Tan, Fengbin Wang, Lance Bigelow, Ragothaman M. Yennamalli, Robert Jedrzejczak, Gyorgy Babnigg, Craig A. Bingman, Andrzej Joachimiak, Madan K. Kharel, Shanteri Singh, Jon S. Thorson, George Phillips

    http://dx.doi.org/10.1063/1.4948539 journal-article Cao, H. et al., 2016. Structural dynamics of a methionine γ-lyase for calicheamicin biosynthesis: Rotation of the conserved tyrosine stacking with pyridoxal phosphate. Structural Dynamics, 3(3), p.034702. Available at: …

  72. Structural enzymology using X-ray free electron lasers

    0.0 out of 5 stars 

    15 Dec 2016 | BioXFEL Publications | Contributor(s): Christopher Kupitz, Jose L. Olmos, Mark Holl, Lee Tremblay, Kanupriya Pande, Suraj Pandey, Dominik Oberthür, Mark S. Hunter, Mengning Liang, Andrew Aquila, Jason Tenboer, George Douglas Calvey, Andrea Katz, Yujie Chen, Max Oliver Wiedorn, Juraj Knoska, Alke Meents, Valerio Majriani, Tyler Norwood, Ishwor Poudyal, Thomas Grant, Mitchell Miller, Weijun Xu, Aleksandra Tolstikova, Andrew Morgan, Markus Metz, Jose M. Martin-Garcia, James D Zook, Shatabdi Roy-Chowdhury, Jesse David Coe, Nirupa Nagaratnam, Domingo Meza, Raimund Fromme, Shibom Basu, Matthias Frank, Thomas White, Anton Barty, Sasa Bajt, Oleksandr Yefanov, Henry Chapman, Nadia Zatsepin, Garrett Charles Nelson, Uwe Weierstall, John Spence, Peter Schwander, Lois Pollack, Petra Fromme, Abbas Ourmazd, George Phillips, Marius Schmidt

    http://dx.doi.org/10.1063/1.4972069 Christopher Kupitz and Jose L. Olmos and Mark Holl and Lee Tremblay and Kanupriya Pande and Suraj Pandey and Dominik Oberthür and Mark Hunter and Mengning Liang and Andrew Aquila and Jason Tenboer and George Calvey and Andrea Katz and Yujie Chen and Max O. …

  73. Structural insight into host plasma membrane association and assembly of HIV-1 Matrix protein

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    21 Feb 2021 | BioXFEL Publications | Contributor(s): Halilibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Kensaku Anraku, Kazuaki Monde, Çağdaş Dağ, Ebru Destan, Busra Yuksel, Esra Ayan, Gunseli Yildirim, Merve Yigin, F. Betul Ertem, Alaleh Shafiei, Omur Guven, Sabri O. Besler, Raymond G. Sierra, Chun Hong Yoon, Zhen Su, Mengling Liang, Burcin Acar, Turkan Haliloglu, Masami Otsuka, Fumiaki Yumoto, Mikako Fujita, Toshiya Senda, Hasan Demirci

    http://dx.doi.org/10.1101/2021.02.21.432153 ABSTRACTHIV-1 continues to be a global health concern since AIDS was first recognized by the World Health Organization (WHO). It is estimated that there were 38 million people infected with HIV-1 and 1.5 million deaths in 2019 alone. A better …

  74. Structural insight into host plasma membrane association and assembly of HIV-1 matrix protein

    0.0 out of 5 stars 

    04 Aug 2021 | BioXFEL Publications | Contributor(s): Halilibrahim Ciftci, Hiroshi Tateishi, Kotaro Koiwai, Ryoko Koga, Kensaku Anraku, Kazuaki Monde, Çağdaş Dağ, Ebru Destan, Busra Yuksel, Esra Ayan, Gunseli Yildirim, Merve Yigin, F. Betul Ertem, Alaleh Shafiei, Omur Guven, Sabri O. Besler, Raymond G. Sierra, Chun Hong Yoon, Zhen Su, Mengling Liang, Burcin Acar, Turkan Haliloglu, Masami Otsuka, Fumiaki Yumoto, Mikako Fujita, Toshiya Senda, Hasan Demirci

    http://dx.doi.org/10.1038/s41598-021-95236-8 AbstractOligomerization of Pr55Gag is a critical step of the late stage of the HIV life cycle. It has been known that the binding of IP6, an abundant endogenous cyclitol molecule at the MA domain, has been linked to the oligomerization of Pr55Gag. …

  75. Structural insights into bifunctional thaumarchaeal crotonyl-CoA hydratase and 3-hydroxypropionyl-CoA dehydratase from Nitrosopumilus maritimus

    0.0 out of 5 stars 

    24 Nov 2021 | BioXFEL Publications | Contributor(s): Ebru Destan, Busra Yuksel, Bradley B. Tolar, Esra Ayan, Sam Deutsch, Yasuo Yoshikuni, Soichi Wakatsuki, Christopher A. Francis, Hasan Demirci

    http://dx.doi.org/10.1038/s41598-021-02180-8 AbstractThe ammonia-oxidizing thaumarchaeal 3-hydroxypropionate/4-hydroxybutyrate (3HP/4HB) cycle is one of the most energy-efficient CO2 fixation cycles discovered thus far. The protein encoded by Nmar_1308 (from Nitrosopumilus maritimus SCM1) is a …

  76. Structural insights into conformational switching in latency-associated peptide between transforming growth factor β-1 bound and unbound states

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    05 Feb 2020 | BioXFEL Publications | Contributor(s): Timothy R. Stachowski, Mary E. Snell, Edward Snell

    http://dx.doi.org/10.1107/s205225251901707x Transforming growth factor β-1 (TGFβ-1) is a secreted signalling protein that directs many cellular processes and is an attractive target for the treatment of several diseases. The primary endogenous activity regulatory mechanism for TGFβ-1 is …

  77. Structural Insights into Melatonin Receptors

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    06 Nov 2019 | BioXFEL Publications | Contributor(s): Benjamin Stauch, Linda C. Johansson, Vadim Cherezov

    http://dx.doi.org/10.1111/febs.15128 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Stauch, B., Johansson, L.C. & Cherezov, V., 2019. Structural Insights into Melatonin Receptors. The FEBS Journal. Available at: http://dx.doi.org/10.1111/febs.15128. Benjamin Stauch and Linda C. …

  78. Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody

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    17 Jul 2017 | BioXFEL Publications | Contributor(s): Andrii Ishchenko, Daniel Wacker, Mili Kapoor, Ai Zhang, Gye Won Han, Shibom Basu, Nilkanth N Patel, Marc Messerschmidt, Uwe Weierstall, Wei Liu, Vsevolod Katritch, Bryan L. Roth, Raymond C. Stevens, Vadim Cherezov

    http://dx.doi.org/10.1073/pnas.1700891114 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Ishchenko, A. et al., 2017. Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody. Proceedings of the National Academy of Sciences, …

  79. Structural knowledge or X-ray damage? A case study on xylose isomerase illustrating both

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    24 Jun 2019 | BioXFEL Publications | Contributor(s): Helena Taberman, Charles S. Bury, Mark J. Van Der Woerd, Edward Snell, Elspeth F. Garman

    http://dx.doi.org/10.1107/s1600577519005599 Xylose isomerase (XI) is an industrially important metalloprotein studied for decades. Its reaction mechanism has been postulated to involve movement of the catalytic metal cofactor to several different conformations. Here, a dose-dependent approach was …

  80. Structural knowledge or X-ray damage? Dose-dependent case studies on xylose isomerase revealing structural perturbations

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    03 Jan 2020 | BioXFEL Publications | Contributor(s): Edward Snell, Helena Taberman, Charles S. Bury, Mark J. Van Der Woerd, Elspeth F. Garman

    http://dx.doi.org/10.1107/s010876731909771x poster NSF-STC Biology with X-ray Lasers (NSF-1231306) Snell, E.H. et al., 1999. Structural knowledge or X-ray damage? Dose-dependent case studies on xylose isomerase revealing structural perturbations. Acta Crystallographica Section A Foundations and …

  81. Structural studies of P-type ATPase–ligand complexes using an X-ray free-electron laser

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    11 Jun 2015 | BioXFEL Publications | Contributor(s): Maike Bublitz, Karol Nass, Nikolaj D. Drachmann, Anders J. Markvardsen, Matthias J. Gutmann, Thomas R. M. Barends, Daniel Mattle, Robert L. Shoeman, R. Bruce Doak, Sébastien Boutet, Marc Messerschmidt, Marvin M. Seibert, Garth J. Williams, Lutz Foucar, Linda Reinhard, Oleg Sitsel, Jonas L. Gregersen, Johannes D. Clausen, Thomas Boesen, Kamil Gotfryd, Kai-Tuo Wang, Claus Olesen, Jesper V. Møller, Poul Nissen, Ilme Schlichting

    Membrane proteins are key players in biological systems, mediating signalling events and the specific transport ofe.g.ions and metabolites. Consequently, membrane proteins are targeted by a large number of currently approved drugs. Understanding their functions and molecular mechanisms is greatly …

  82. Structural Studies of the Human Kappa Opioid Receptor Active State Conformations

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    16 Feb 2016 | BioXFEL Publications | Contributor(s): Ming-Yue Lee, Nilkanth N Patel, Vsevolod Katritch, Raymond C. Stevens, Vadim Cherezov

    http://dx.doi.org/10.1016/j.bpj.2015.11.275 Ming-Yue Lee and Nilkanth Patel and Vsevolod Katritch and Raymond C. Stevens and Vadim Cherezov Lee, M.-Y. et al., 2016. Structural Studies of the Human Kappa Opioid Receptor Active State Conformations. Biophysical Journal, 110(3), p.38a–39a. Available …

  83. Structure and Function of REP34 Implicates Carboxypeptidase Activity inFrancisella tularensisHost Cell Invasion

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    18 Sep 2014 | BioXFEL Publications | Contributor(s): Geoffrey K. Feld, Sahar El-Etr, Michele H. Corzett, Mark S. Hunter, Kamila Belhocine, Denise M. Monack, Matthias Frank, Brent W. Segelke, Amy Rasley

    http://dx.doi.org/10.1074/jbc.m114.599381 journal-article Feld, G.K. et al., 2014. Structure and Function of REP34 Implicates Carboxypeptidase Activity inFrancisella tularensisHost Cell Invasion. Journal of Biological Chemistry, 289(44), pp.30668–30679. Available at: …

  84. Structure and specificity of a permissive bacterial C-prenyltransferase

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    06 Feb 2017 | BioXFEL Publications | Contributor(s): Sherif I Elshahawi, Hongnan Cao, Khaled A Shaaban, Larissa V Ponomareva, Thangaiah Subramanian, Mark L Farman, H Peter Spielmann, George Phillips, Jon S Thorson, Shanteri Singh

    journal-article http://dx.doi.org/10.1038/nchembio.2285 Elshahawi, S.I. et al., 2017. Structure and specificity of a permissive bacterial C-prenyltransferase. Nature Chemical Biology, 13(4), pp.366–368. Available at: http://dx.doi.org/10.1038/nchembio.2285. Sherif I Elshahawi and Hongnan Cao …

  85. Structure and Substrate Specificity of a Eukaryotic Fucosidase fromFusarium graminearum

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    02 Aug 2014 | BioXFEL Publications | Contributor(s): Hongnan Cao, Jonathan D. Walton, Phil Brumm, George Phillips

    http://dx.doi.org/10.1074/jbc.m114.583286 journal-article Cao, H. et al., 2014. Structure and Substrate Specificity of a Eukaryotic Fucosidase fromFusarium graminearum. Journal of Biological Chemistry, 289(37), pp.25624–25638. Available at: http://dx.doi.org/10.1074/jbc.m114.583286. Hongnan …

  86. Structure determination based on continuous diffraction from macromolecular crystals

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    14 Sep 2017 | BioXFEL Publications | Contributor(s): Henry Chapman, Petra Fromme

    http://dx.doi.org/10.1016/j.sbi.2017.07.008 journal-article Chapman, H.N. & Fromme, P., 2017. Structure determination based on continuous diffraction from macromolecular crystals. Current Opinion in Structural Biology, 45, pp.170–177. Available at: http://dx.doi.org/10.1016/j.sbi.2017.07.008. …

  87. Structure Determination from Disordered Ensembles of Identical Particles

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    22 Mar 2013 | BioXFEL Publications | Contributor(s): Richard Kirian, Dilano Saldin

    http://dx.doi.org/10.1080/08940886.2013.771070 journal-article Kirian, R.A. & Saldin, D.K., 2013. Structure Determination from Disordered Ensembles of Identical Particles. Synchrotron Radiation News, 26(2), pp.20–25. Available at: http://dx.doi.org/10.1080/08940886.2013.771070. Richard A. …

  88. Structure Determination from Lipidic Cubic Phase Embedded Microcrystals by MicroED

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    30 Jul 2020 | BioXFEL Publications | Contributor(s): Lan Zhu, Guanhong Bu, Liang Jing, Dan Shi, Ming-Yue Lee, Tamir Gonen, Wei Liu, Brent L. Nannenga

    http://dx.doi.org/10.1016/j.str.2020.07.006 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Zhu, L. et al., 2020. Structure Determination from Lipidic Cubic Phase Embedded Microcrystals by MicroED. Structure, 28(10), pp.1149–1159.e4. Available at: …

  89. Structure Determination from Multiple-Scattering Electron Crystallography

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    22 Jul 2022 | BioXFEL Publications | Contributor(s): Jeffrey Donatelli, John Spence

    http://dx.doi.org/10.1017/s1431927622010418 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Donatelli, J., & Spence, J. (2022). Structure Determination from Multiple-Scattering Electron Crystallography. Microscopy and Microanalysis, 28(S1), 2766–2767. …

  90. Structure determination with weak anomalous signal

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    24 Apr 2015 | BioXFEL Publications | Contributor(s): Thomas Charles Terwilliger, Li-Wei Hung, Paul D. Adams, Nathanial D Echols, Ralf Grosse-Kunstleve, James Holton, Gabor Bunkoczi, Randy J. Read, David Akey, Janet Smith

    http://dx.doi.org/10.2172/1178320 Thomas Charles Terwilliger and Li-Wei Hung and Paul D. Adams and Nathanial D Echols and Ralf Grosse-Kunstleve and James Holton and Gabor Bunkoczi and Randy J. Read and David Akey and Janet Smith Terwilliger, T.C. et al., 2015. Structure determination with weak …

  91. Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex

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    09 Sep 2016 | BioXFEL Publications | Contributor(s): Philip J. Robinson, Michael J. Trnka, David Bushnell, Ralph E. Davis, Pierre-Jean Mattei, Alma L. Burlingame, Roger Kornberg

    http://dx.doi.org/10.1016/j.cell.2016.08.050 Philip J. Robinson and Michael J. Trnka and David A. Bushnell and Ralph E. Davis and Pierre-Jean Mattei and Alma L. Burlingame and Roger D. Kornberg Robinson, P.J. et al., 2016. Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex. …

  92. Structure of a cupin protein Plu4264 from Photorhabdus luminescens subsp. laumondii TTO1 at 1.35 Å resolution

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    30 Oct 2014 | BioXFEL Publications | Contributor(s): R. Sophia Weerth, Karolina Michalska, Craig A. Bingman, Ragothaman M. Yennamalli, Hui Li, Robert Jedrzejczak, Fengbin Wang, Gyorgy Babnigg, Andrzej Joachimiak, Michael G. Thomas, George Phillips

    http://dx.doi.org/10.1002/prot.24705 journal-article Weerth, R.S. et al., 2014. Structure of a cupin protein Plu4264 from Photorhabdus luminescens subsp. laumondii TTO1 at 1.35 Å resolution. Proteins: Structure, Function, and Bioinformatics, 83(2), pp.383–388. Available at: …

  93. Structure of a cupin protein Plu4264 from Photorhabdus luminescens subsp. laumondii TTO1 at 1.35 Å resolution

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    14 Apr 2015 | BioXFEL Publications | Contributor(s): R. Sophia Weerth, Karolina Michalska, Craig A. Bingman, Ragothaman M. Yennamalli, Hui Li, Robert Jedrzejczak, Fengbin Wang, Gyorgy Babnigg, Andrzej Joachimiak, Michael G. Thomas, George Phillips

    http://dx.doi.org/10.1002/prot.24798 R. Sophia Weerth and Karolina Michalska and Craig A. Bingman and Ragothaman M. Yennamalli and Hui Li and Robert Jedrzejczak and Fengbin Wang and Gyorgy Babnigg and Andrzej Joachimiak and Michael G. Thomas and George N. Phillips Sophia Weerth, R. et al., 2015. …

  94. Structure of a photosynthetic reaction centre determined by serial femtosecond crystallography

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    19 Dec 2013 | BioXFEL Publications | Contributor(s): Linda C. Johansson, David Arnlund, Gergely Katona, Thomas A. White, Anton Barty, Daniel P. DePonte, Robert L. Shoeman, Cecilia Wickstrand, Amit Sharma, Garth J. Williams, Andrew Aquila, Michael J. Bogan, Carl Caleman, Jan Davidsson, R Bruce Doak, Matthias Frank, Raimund Fromme, Lorenzo Galli, Ingo Grotjohann, Mark S. Hunter, Stephan Kassemeyer, Richard Kirian, Christopher Kupitz, Mengning Liang, Lukas Lomb, Erik Malmerberg, Andrew V. Martin, Marc Messerschmidt, Karol Nass, Lars Redecke, M Marvin Seibert, Jennie Sjöhamn, Jan Steinbrener, Francesco Stellato, Dingjie Wang, Weixaio Y. Wahlgren, Uwe Weierstall, Sebastian Westenhoff, Nadia Zatsepin, Sébastien Boutet, John Spence, Ilme Schlichting, Henry Chapman, Petra Fromme, Richard Neutze

    http://dx.doi.org/10.1038/ncomms3911 Linda C. Johansson and David Arnlund and Gergely Katona and Thomas A. White and Anton Barty and Daniel P. DePonte and Robert L. Shoeman and Cecilia Wickstrand and Amit Sharma and Garth J. Williams and Andrew Aquila and Michael J. Bogan and Carl Caleman and Jan …

  95. Structure of an RNA polymerase II preinitiation complex

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    20 Oct 2015 | BioXFEL Publications | Contributor(s): Kenji Murakami, Kuang-Lei Tsai, Nir Kalisman, David Bushnell, Francisco J. Asturias, Roger Kornberg

    journal-article http://dx.doi.org/10.1073/pnas.1518255112 Murakami, K. et al., 2015. Structure of an RNA polymerase II preinitiation complex. Proceedings of the National Academy of Sciences, 112(44), pp.13543–13548. Available at: http://dx.doi.org/10.1073/pnas.1518255112. Kenji Murakami and …

  96. Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists

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    06 Dec 2016 | BioXFEL Publications | Contributor(s): Yi Zheng, Ling Qin, Natalia V. Ortiz Zacarías, Henk De Vries, Gye Won Han, Martin Gustavsson, Marta Dabros, Chunxia Zhao, Robert J. Cherney, Percy Carter, Dean Stamos, Ruben Abagyan, Vadim Cherezov, Raymond C. Stevens, Adriaan P. IJzerman, Laura H. Heitman, Andrew Tebben, Irina Kufareva, Tracy M. Handel

    http://dx.doi.org/10.1038/nature20605 journal-article Zheng, Y. et al., 2016. Structure of CC chemokine receptor 2 with orthosteric and allosteric antagonists. Nature, 540(7633), pp.458–461. Available at: http://dx.doi.org/10.1038/nature20605. Yi Zheng and Ling Qin and Natalia V. Ortiz …

  97. Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV

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    21 Jun 2017 | BioXFEL Publications | Contributor(s): Yi Zheng, Gye Won Han, Ruben Abagyan, Beili Wu, Raymond C. Stevens, Vadim Cherezov, Irina Kufareva, Tracy M. Handel

    http://dx.doi.org/10.1016/j.immuni.2017.05.002 journal-article Zheng, Y. et al., 2017. Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV. Immunity, 46(6), pp.1005–1017.e5. Available at: …

  98. Structure of CPV17 polyhedrin determined by the improved analysis of serial femtosecond crystallographic data

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    09 Mar 2015 | BioXFEL Publications | Contributor(s): Helen M. Ginn, Marc Messerschmidt, Xiaoyun Ji, Hanwen Zhang, Danny Axford, Richard J. Gildea, Graeme Winter, Aaron S. Brewster, Johan Hattne, Armin Wagner, Jonathan M. Grimes, Gwyndaf Evans, Nicholas K. Sauter, Geoff Sutton, David I. Stuart

    http://dx.doi.org/10.1038/ncomms7435 Helen M. Ginn and Marc Messerschmidt and Xiaoyun Ji and Hanwen Zhang and Danny Axford and Richard J. Gildea and Graeme Winter and Aaron S. Brewster and Johan Hattne and Armin Wagner and Jonathan M. Grimes and Gwyndaf Evans and Nicholas K. Sauter and Geoff Sutton …

  99. Structure of photosystem II and substrate binding at room temperature

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    18 Nov 2016 | BioXFEL Publications | Contributor(s): Iris Diane Young, Mohamed Ibrahim, Ruchira Chatterjee, Sheraz Gul, Franklin D. Fuller, Sergey Koroidov, Aaron S. Brewster, Rosalie Tran, Roberto Alonso-Mori, Thomas Kroll, Tara Michels-Clark, Hartawan Laksmono, Raymond G. Sierra, Claudiu A. Stan, Rana Hussein, Miao Zhang, Lacey Douthit, Markus Kubin, Casper De Lichtenberg, Long Vo Pham, Håkan Nilsson, Mun Hon Cheah, Dmitriy Shevela, Claudio Saracini, Mackenzie A. Bean, Ina Seuffert, Dimosthenis Sokaras, Tsu-Chien Weng, Ernest Pastor, Clemens Weninger, Thomas Fransson, Louise Lassalle, Philipp Bräuer, Pierre Aller, Peter T. Docker, Babak Andi, Allen M. Orville, James M. Glownia, Silke Nelson, Marcin Sikorski, Diling Zhu, Mark S. Hunter, Thomas J. Lane, Andy Aquila, Jason E. Koglin, Joseph Robinson, Mengning Liang, Sébastien Boutet, Artem Y. Lyubimov, Monarin Uervirojnangkoorn, Nigel W. Moriarty, Dorothee Liebschner, Pavel V. Afonine, David G. Waterman, Gwyndaf Evans, Philippe Wernet, Holger Dobbek, William I. Weis, Axel T. Brunger, Petrus H. Zwart, Paul D. Adams, Athina Zouni, Johannes Messinger, Uwe Bergmann, Nicholas K. Sauter, Jan Kern, Vittal K. Yachandra, Junko Yano

    http://dx.doi.org/10.1038/nature20161 Iris D. Young and Mohamed Ibrahim and Ruchira Chatterjee and Sheraz Gul and Franklin D. Fuller and Sergey Koroidov and Aaron S. Brewster and Rosalie Tran and Roberto Alonso-Mori and Thomas Kroll and Tara Michels-Clark and Hartawan Laksmono and Raymond G. Sierra …

  100. Structure of RNA 3′-phosphate cyclase bound to substrate RNA

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    27 Aug 2014 | BioXFEL Publications | Contributor(s): Kevin K. Desai, Craig A. Bingman, Chin L. Cheng, George Phillips, Ronald T. Raines

    http://dx.doi.org/10.1261/rna.045823.114 journal-article Desai, K.K. et al., 2014. Structure of RNA 3′-phosphate cyclase bound to substrate RNA. RNA, 20(10), pp.1560–1566. Available at: http://dx.doi.org/10.1261/rna.045823.114. Kevin K. Desai and Craig A. Bingman and Chin L. Cheng and George …