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  1. Simultaneous retrieval of coherently illuminated defocused objects

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    05 Jul 2018 | BioXFEL Publications | Contributor(s): Joe Chen, Richard Kirian

    http://dx.doi.org/10.1109/ivcnz.2017.8402481 proceedings-article Chen, J.P.J. & Kirian, R.A., 2017. Simultaneous retrieval of coherently illuminated defocused objects. 2017 International Conference on Image and Vision Computing New Zealand (IVCNZ). Available at: …

  2. Computational design of thermostabilizing point mutations for G protein-coupled receptors

    0.0 out of 5 stars 

    21 Jun 2018 | BioXFEL Publications | Contributor(s): Petr Popov, Yao Peng, Ling Shen, Raymond C Stevens, Vadim Cherezov, Zhi-Jie Liu, Vsevolod Katritch

    http://dx.doi.org/10.7554/elife.34729 Engineering of GPCR constructs with improved thermostability is a key for successful structural and biochemical studies of this transmembrane protein family, targeted by 40% of all therapeutic drugs. Here we introduce a comprehensive computational approach to …

  3. Chapter 2. Delivery of GPCR Crystals for Serial Femtosecond Crystallography

    0.0 out of 5 stars 

    19 Jun 2018 | BioXFEL Publications | Contributor(s): E. E. Abola, U. Weierstall, W. Liu, V. Cherezov

    http://dx.doi.org/10.1039/9781788010504-00028 book-chapter Abola, E.E. et al., Chapter 2. Delivery of GPCR Crystals for Serial Femtosecond Crystallography. Chemical Biology, pp.28–53. Available at: http://dx.doi.org/10.1039/9781788010504-00028. E. E. Abola and U. Weierstall and W. Liu and V. …

  4. Chapter 8. Crystallography with X-ray Free Electron Lasers

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    19 Jun 2018 | BioXFEL Publications | Contributor(s): N. A. Zatsepin

    http://dx.doi.org/10.1039/9781788010504-00181 book-chapter NSF-STC Biology with X-ray Lasers (NSF-1231306) Zatsepin, N.A., Chapter 8. Crystallography with X-ray Free Electron Lasers. Chemical Biology, pp.181–224. Available at: http://dx.doi.org/10.1039/9781788010504-00181. N. A. Zatsepin

  5. Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser

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    14 Jun 2018 | BioXFEL Publications | Contributor(s): Przemyslaw Nogly, Tobias Weinert, Daniel James, Sergio Carbajo, Dmitry Ozerov, Antonia Furrer, Dardan Gashi, Veniamin Borin, Petr Skopintsev, Kathrin Jaeger, Karol Nass, Petra Båth, Robert William Bosman, Jason Koglin, Matthew Seaberg, Thomas Lane, Demet Kekilli, Steffen Brünle, Tomoyuki Tanaka, Wenting Wu, Christopher Milne, Thomas White, Anton Barty, Uwe Weierstall, Valerie Panneels, Eriko Nango, So Iwata, Mark S. Hunter, Igor Schapiro, Gebhard F.X. Schertler, Richard Neutze, Jörg Standfuss

    http://dx.doi.org/10.1126/science.aat0094 journal-article Nogly, P. et al., 2018. Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser. Science, p.eaat0094. Available at: http://dx.doi.org/10.1126/science.aat0094. Przemyslaw Nogly and Tobias Weinert and Daniel James …

  6. An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering

    0.0 out of 5 stars 

    06 Jun 2018 | BioXFEL Publications | Contributor(s): Daniel A Keedy, Zachary B Hill, Justin T Biel, Emily Kang, T Justin Rettenmaier, José Brandão-Neto, Nicholas M Pearce, Frank Von Delft, James A Wells, James Fraser

    http://dx.doi.org/10.7554/elife.36307 Allostery is an inherent feature of proteins, but it remains challenging to reveal the mechanisms by which allosteric signals propagate. A clearer understanding of this intrinsic circuitry would afford new opportunities to modulate protein function. Here, we …

  7. Enzyme intermediates captured “on the fly” by mix-and-inject serial crystallography

    0.0 out of 5 stars 

    30 May 2018 | BioXFEL Publications | Contributor(s): Jose L. Olmos, Suraj Pandey, Jose M. Martin-Garcia, George Douglas Calvey, Andrea Katz, Juraj Knoska, Christopher Kupitz, Mark S. Hunter, Mengning Liang, Dominik Oberthuer, Oleksandr Yefanov, Max Oliver Wiedorn, Michael Heyman, Mark Holl, Kanupriya Pande, Anton Barty, Mitchell Miller, Stephan Stern, Shatabdi Roy-Chowdhury, Jesse David Coe, Nirupa Nagaratnam, James D Zook, Jacob Christopher Verburgt, Tyler Norwood, Ishwor Poudyal, David Xu, Jason Koglin, Matthew H. Seaberg, Yun Zhao, Saša Bajt, Thomas Grant, Valerio Mariani, Garrett Charles Nelson, GANESH SUBRAMANIAN, Euiyoung Bae, Raimund Fromme, Russell Fung, Peter Schwander, Matthias Frank, Thomas A. White, Uwe Weierstall, Nadia Zatsepin, John Spence, Petra Fromme, Henry Chapman, Lois Pollack, Lee Tremblay, Abbas Ourmazd, George Phillips, Marius Schmidt

    http://dx.doi.org/10.1186/s12915-018-0524-5 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Olmos, J.L. et al., 2018. Enzyme intermediates captured “on the fly” by mix-and-inject serial crystallography. BMC Biology, 16(1). Available at: …

  8. Difference structures from time-resolved small-angle and wide-angle x-ray scattering

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    17 May 2018 | BioXFEL Publications | Contributor(s): Prakash Nepal, D. K. Saldin

    http://dx.doi.org/10.1103/physrevb.97.195426 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Nepal, P. & Saldin, D.K., 2018. Difference structures from time-resolved small-angle and wide-angle x-ray scattering. Physical Review B, 97(19). Available at: …

  9. Ultrafast nonthermal heating of water initiated by an X-ray Free-Electron Laser

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    14 May 2018 | BioXFEL Publications | Contributor(s): Kenneth R. Beyerlein, H. Olof Jönsson, Roberto Alonso-Mori, Andrew Aquila, Saša Bajt, Anton Barty, Richard Bean, Jason E. Koglin, Marc Messerschmidt, Davide Ragazzon, Dimosthenis Sokaras, Garth J. Williams, Stefan Hau-Riege, Sébastien Boutet, Henry Chapman, Nicuşor Tîmneanu, Carl Caleman

    http://dx.doi.org/10.1073/pnas.1711220115 journal-article Beyerlein, K.R. et al., 2018. Ultrafast nonthermal heating of water initiated by an X-ray Free-Electron Laser. Proceedings of the National Academy of Sciences, p.201711220. Available at: http://dx.doi.org/10.1073/pnas.1711220115. Kenneth …

  10. Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene

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    03 May 2018 | BioXFEL Publications | Contributor(s): Carolin Seuring, Kartik Ayyer, Eleftheria Filippaki, Miriam Barthelmess, Jean-Nicolas Longchamp, Philippe Ringler, Tommaso Pardini, David H. Wojtas, Matthew Coleman, Katerina Dörner, Silje Fuglerud, Greger Hammarin, Birgit Habenstein, Annette E. Langkilde, Antoine Loquet, Alke Meents, Roland Riek, Henning Stahlberg, Sébastien Boutet, Mark S. Hunter, Jason Koglin, Mengning Liang, Helen M. Ginn, Rick P. Millane, Matthias Frank, Anton Barty, Henry Chapman

    http://dx.doi.org/10.1038/s41467-018-04116-9 journal-article Seuring, C. et al., 2018. Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene. Nature Communications, 9(1). Available at: http://dx.doi.org/10.1038/s41467-018-04116-9. Carolin Seuring and Kartik …

  11. Microfluidic Chips for In Situ Crystal X-ray Diffraction and In Situ Dynamic Light Scattering for Serial Crystallography

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    24 Apr 2018 | BioXFEL Publications | Contributor(s): Yannig Gicquel, Robin Schubert, Svetlana Kapis, Gleb Bourenkov, Thomas Schneider, Markus Perbandt, Christian Betzel, Henry Chapman, Michael Heymann

    http://dx.doi.org/10.3791/57133 journal-article Gicquel, Y. et al., 2018. Microfluidic Chips for In Situ Crystal X-ray Diffraction and In Situ Dynamic Light Scattering for Serial Crystallography. Journal of Visualized Experiments, (134). Available at: http://dx.doi.org/10.3791/57133. Yannig …

  12. Revealing the distinct folding phases of an RNA three-helix junction

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    24 Apr 2018 | BioXFEL Publications | Contributor(s): Alex Plumridge, Andrea Katz, George Douglas Calvey, Ron Elber, Serdal Kirmizialtin, Lois Pollack

    http://dx.doi.org/10.1093/nar/gky363 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Plumridge, A. et al., 2018. Revealing the distinct folding phases of an RNA three-helix junction. Nucleic Acids Research. Available at: http://dx.doi.org/10.1093/nar/gky363. Alex Plumridge and …

  13. Molecular biophysical characterization of the third FF domain of Homo sapiens Prp40 homolog A

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    19 Apr 2018 | BioXFEL Publications | Contributor(s): Adalberto Díaz Casas, Gabriela Casanova Sepúlveda, Odalys Sánchez Negrón, Andrea P. Caro Muñiz, Stewart R. Malavé Ramos, Ana R. Cebollero López, Belinda Pastrana-Ríos

    http://dx.doi.org/10.1016/j.molstruc.2018.04.059 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Díaz Casas, A. et al., 2018. Molecular biophysical characterization of the third FF domain of Homo sapiens Prp40 homolog A. Journal of Molecular Structure, 1167, pp.174–179. …

  14. Trajectories of the ribosome as a Brownian nanomachine

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    12 Apr 2018 | BioXFEL Publications | Contributor(s): Ali Dashti, Peter Schwander, Robert Langlois, Russell Fung, Wen Li, Ahmad Hosseinizadeh, Hstau Y. Liao, Jesper Pallesen, Gyanesh Sharma, Vera A. Stupina, Anne E. Simon, Jonathan D. Dinman, Joachim Frank, Abbas Ourmazd

    http://dx.doi.org/10.1142/9789813234864_0048 book-chapter Dashti, A. et al., 2018. Trajectories of the ribosome as a Brownian nanomachine. Single-Particle Cryo-Electron Microscopy, pp.463–475. Available at: http://dx.doi.org/10.1142/9789813234864_0048. Ali Dashti and Peter Schwander and Robert …

  15. Dose efficient Compton X-ray microscopy

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    10 Apr 2018 | BioXFEL Publications | Contributor(s): P. Villanueva-Perez, S. Bajt, H. N. Chapman

    http://dx.doi.org/10.1364/optica.5.000450 journal-article Villanueva-Perez, P., Bajt, S. & Chapman, H.N., 2018. Dose efficient Compton X-ray microscopy. Optica, 5(4), p.450. Available at: http://dx.doi.org/10.1364/optica.5.000450. P. Villanueva-Perez and S. Bajt and H. N. Chapman

  16. X-ray and UV radiation-damage-induced phasing using synchrotron serial crystallography

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    06 Apr 2018 | BioXFEL Publications | Contributor(s): Nicolas Foos, Carolin Seuring, Robin Schubert, Anja Burkhardt, Olof Svensson, Alke Meents, Henry Chapman, Max H. Nanao

    http://dx.doi.org/10.1107/s2059798318001535 Specific radiation damage can be used to determine phases de novo from macromolecular crystals. This method is known as radiation-damage-induced phasing (RIP). One limitation of the method is that the dose of individual data sets must be minimized, which …

  17. Rescue of conformational dynamics in enzyme catalysis by directed evolution

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    03 Apr 2018 | BioXFEL Publications | Contributor(s): Renee Otten, Lin Liu, Lillian R. Kenner, Michael W. Clarkson, David Mavor, Dan S. Tawfik, Dorothee Kern, James Fraser

    http://dx.doi.org/10.1038/s41467-018-03562-9 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Otten, R. et al., 2018. Rescue of conformational dynamics in enzyme catalysis by directed evolution. Nature Communications, 9(1). Available at: …

  18. Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots

    0.0 out of 5 stars 

    30 Mar 2018 | BioXFEL Publications | Contributor(s): Ali Dashti, Mrinal Shekhar, Danya Ben Hail, Ghoncheh Mashayekhi, Peter Schwander, Amedee Des Georges, Joachim Frank, Abhishek Singharoy, Abbas Ourmazd

    http://dx.doi.org/10.1101/291922 We present a new approach to determining the conformational changes associated with biological function, and demonstrate its capabilities in the context of experimental single-particle cryo-EM snapshots of ryanodine receptor (RyR1), a Ca2+-channel involved in …

  19. X-ray focusing with efficient high-NA multilayer Laue lenses

    0.0 out of 5 stars 

    23 Mar 2018 | BioXFEL Publications | Contributor(s): Saša Bajt, Mauro Prasciolu, Holger Fleckenstein, Martin Domaracký, Henry Chapman, Andrew J Morgan, Oleksandr Yefanov, Marc Messerschmidt, Yang Du, Kevin T Murray, Valerio Mariani, Manuela Kuhn, Steven Aplin, Kanupriya Pande, Pablo Villanueva-Perez, Karolina Stachnik, Joe Chen, Andrzej Andrejczuk, Alke Meents, Anja Burkhardt, David Pennicard, Xiaojing Huang, Hanfei Yan, Evgeny Nazaretski, Yong S Chu, Christian E Hamm

    http://dx.doi.org/10.1038/lsa.2017.162 journal-article Bajt, S. et al., 2017. X-ray focusing with efficient high-NA multilayer Laue lenses. Light: Science & Applications, 7(3), p.17162. Available at: http://dx.doi.org/10.1038/lsa.2017.162. Saša Bajt and Mauro Prasciolu and Holger Fleckenstein …

  20. The ATPase motor of the Chd1 chromatin remodeler stimulates DNA unwrapping from the nucleosome

    0.0 out of 5 stars 

    16 Mar 2018 | BioXFEL Publications | Contributor(s): Joshua M Tokuda, Ren Ren, Robert F Levendosky, Rebecca J Tay, Ming Yan, Lois Pollack, Gregory D Bowman

    http://dx.doi.org/10.1093/nar/gky206 journal-article Tokuda, J.M. et al., 2018. The ATPase motor of the Chd1 chromatin remodeler stimulates DNA unwrapping from the nucleosome. Nucleic Acids Research, 46(10), pp.4978–4990. Available at: http://dx.doi.org/10.1093/nar/gky206. Joshua M Tokuda and …

  21. Structural biology of G protein-coupled receptors: new opportunities from XFELs and cryoEM

    0.0 out of 5 stars 

    16 Mar 2018 | BioXFEL Publications | Contributor(s): Andrii Ishchenko, Cornelius Gati, Vadim Cherezov

    http://dx.doi.org/10.1016/j.sbi.2018.03.009 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Ishchenko, A., Gati, C. & Cherezov, V., 2018. Structural biology of G protein-coupled receptors: new opportunities from XFELs and cryoEM. Current Opinion in Structural Biology, 51, …

  22. Serial Femtosecond Crystallography of G Protein–Coupled Receptors

    0.0 out of 5 stars 

    15 Mar 2018 | BioXFEL Publications | Contributor(s): Benjamin Stauch, Vadim Cherezov

    http://dx.doi.org/10.1146/annurev-biophys-070317-033239 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Stauch, B. & Cherezov, V., 2018. Serial Femtosecond Crystallography of G Protein–Coupled Receptors. Annual Review of Biophysics, 47(1). Available at: …

  23. Femtosecond profiling of shaped x-ray pulses

    0.0 out of 5 stars 

    08 Mar 2018 | BioXFEL Publications | Contributor(s): M C Hoffmann, I Grguraš, C Behrens, C Bostedt, J Bozek, H Bromberger, R Coffee, J T Costello, L F DiMauro, Y Ding, G Doumy, W Helml, M Ilchen, R Kienberger, S Lee, A R Maier, T Mazza, M Meyer, M Messerschmidt, S Schorb, W Schweinberger, K Zhang, A L Cavalieri

    http://dx.doi.org/10.1088/1367-2630/aab548 journal-article Hoffmann, M.C. et al., 2018. Femtosecond profiling of shaped x-ray pulses. New Journal of Physics, 20(3), p.033008. Available at: http://dx.doi.org/10.1088/1367-2630/aab548. M C Hoffmann and I Grguraš and C Behrens and C Bostedt and J …

  24. Direct Structural and Chemical Characterization of the Photolytic Intermediates of Methylcobalamin Using Time-Resolved X-ray Absorption Spectroscopy

    0.0 out of 5 stars 

    06 Mar 2018 | BioXFEL Publications | Contributor(s): GANESH SUBRAMANIAN, Xiaoyi Zhang, Gerdenis Kodis, Qingyu Kong, Cunming Liu, Andrew Chizmeshya, Uwe Weierstall, John Spence

    http://dx.doi.org/10.1021/acs.jpclett.8b00083 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Subramanian, G. et al., 2018. Direct Structural and Chemical Characterization of the Photolytic Intermediates of Methylcobalamin Using Time-Resolved X-ray Absorption Spectroscopy. The …

  25. Deterministic Ratchet for Sub-micrometer (Bio)particle Separation

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    06 Mar 2018 | BioXFEL Publications | Contributor(s): Daihyun Kim, Jinghui Luo, Edgar A. Arriaga, Alexandra Ros

    http://dx.doi.org/10.1021/acs.analchem.7b03774 journal-article Kim, D. et al., 2018. Deterministic Ratchet for Sub-micrometer (Bio)particle Separation. Analytical Chemistry. Available at: http://dx.doi.org/10.1021/acs.analchem.7b03774. Daihyun Kim and Jinghui Luo and Edgar A. Arriaga and …

  26. FreeDam – A Webtool for Free-Electron Laser-Induced Damage in Femtosecond X-ray Crystallography

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    21 Feb 2018 | BioXFEL Publications | Contributor(s): H. Olof Jönsson, Christofer Östlin, Howard A. Scott, Henry Chapman, Steve J. Aplin, Nicuşor Tîmneanu, Carl Caleman

    http://dx.doi.org/10.1016/j.hedp.2018.02.004 journal-article Jönsson, H.O. et al., 2018. FreeDam – A Webtool for Free-Electron Laser-Induced Damage in Femtosecond X-ray Crystallography. High Energy Density Physics. Available at: http://dx.doi.org/10.1016/j.hedp.2018.02.004. H. Olof Jönsson …

  27. Femtosecond X-ray Fourier holography imaging of free-flying nanoparticles

    0.0 out of 5 stars 

    16 Feb 2018 | BioXFEL Publications | Contributor(s): Tais Gorkhover, Anatoli Ulmer, Ken Ferguson, Max Bucher, Filipe R. N. C. Maia, Johan Bielecki, Tomas Ekeberg, Max F. Hantke, Benedikt J. Daurer, Carl Nettelblad, Jakob Andreasson, Anton Barty, Petr Bruza, Sebastian Carron, Dirk Hasse, Jacek Krzywinski, Daniel S. D. Larsson, Andrew Morgan, Kerstin Mühlig, Maria Müller, Kenta Okamoto, Alberto Pietrini, Daniela Rupp, Mario Sauppe, Gijs Van Der Schot, Marvin Seibert, Jonas A. Sellberg, Martin Svenda, Michelle Swiggers, Nicusor Timneanu, Daniel Westphal, Garth Williams, Alessandro Zani, Henry Chapman, Gyula Faigel, Thomas Möller, Janos Hajdu, Christoph Bostedt

    http://dx.doi.org/10.1038/s41566-018-0110-y journal-article Gorkhover, T. et al., 2018. Femtosecond X-ray Fourier holography imaging of free-flying nanoparticles. Nature Photonics, 12(3), pp.150–153. Available at: http://dx.doi.org/10.1038/s41566-018-0110-y. Tais Gorkhover and Anatoli Ulmer …

  28. Bringing diffuse X-ray scattering into focus

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    15 Feb 2018 | BioXFEL Publications | Contributor(s): Michael E Wall, Alexander M Wolff, James Fraser

    http://dx.doi.org/10.1016/j.sbi.2018.01.009 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Wall, M.E., Wolff, A.M. & Fraser, J.S., 2018. Bringing diffuse X-ray scattering into focus. Current Opinion in Structural Biology, 50, pp.109–116. Available at: …

  29. Structure of the 30S ribosomal decoding complex at ambient temperature

    0.0 out of 5 stars 

    12 Feb 2018 | BioXFEL Publications | Contributor(s): E. Han Dao, Frederic Poitevin, Raymond G. Sierra, Cornelius Gati, Yashas Rao, Halil Ibrahim Ciftci, Fulya Akşit, Alex McGurk, Trevor Obrinski, Paul Mgbam, Brandon Hayes, Casper De Lichtenberg, Fatima Pardo-Avila, Nicholas Corsepius, Lindsey Zhang, Matt Seaberg, Mark S. Hunter, Mengling Liang, Jason E. Koglin, Soichi Wakatsuki, Hasan Demirci

    http://dx.doi.org/10.1101/262972 The ribosome translates nucleotide sequences of messenger RNA to proteins through selection of cognate transfer RNA according to the genetic code. To date, structural studies of ribosomal decoding complexes yielding high-resolution data have predominantly relied on …

  30. How 2'- O -Methylation in mRNA Disrupts tRNA Decoding during Translation Elongation

    0.0 out of 5 stars 

    06 Feb 2018 | BioXFEL Publications | Contributor(s): Junhong Choi, Gabriele Indrisiunaite, Hasan Demirci, Ka-Weng Ieong, Jinfan Wang, Alexey Petrov, Arjun Prabhakar, Gideon Rechavi, Dan Dominissini, Chuan He, Måns Ehrenberg, Joseph D. Puglisi

    http://dx.doi.org/10.1016/j.bpj.2017.11.3237 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Choi, J. et al., 2018. How 2’- O -Methylation in mRNA Disrupts tRNA Decoding during Translation Elongation. Biophysical Journal, 114(3), p.592a. Available at: …

  31. A Graphene-Based Microfluidic Platform for Electrocrystallization and In Situ X-ray Diffraction

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    02 Feb 2018 | BioXFEL Publications | Contributor(s): Shuo Sui, Yuxi Wang, Christos Dimitrakopoulos, Sarah Perry

    http://dx.doi.org/10.3390/cryst8020076 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Sui, S. et al., 2018. A Graphene-Based Microfluidic Platform for Electrocrystallization and In Situ X-ray Diffraction. Crystals, 8(2), p.76. Available at: http://dx.doi.org/10.3390/cryst8020076. …

  32. Supersaturation-controlled microcrystallization and visualization analysis for serial femtosecond crystallography

    0.0 out of 5 stars 

    01 Feb 2018 | BioXFEL Publications | Contributor(s): Dan Bi Lee, Jong-Min Kim, Jong Hyeon Seok, Ji-Hye Lee, Jae Deok Jo, Ji Young Mun, Chelsie E Conrad, Jesse David Coe, Garrett Charles Nelson, Brenda Hogue, Thomas A. White, Nadia Zatsepin, Uwe Weierstall, Anton Barty, Henry Chapman, Petra Fromme, John Spence, Mi Sook Chung, Chang-Hyun Oh, Kyung Hyun Kim

    http://dx.doi.org/10.1038/s41598-018-20899-9 journal-article Lee, D.B. et al., 2018. Supersaturation-controlled microcrystallization and visualization analysis for serial femtosecond crystallography. Scientific Reports, 8(1). Available at: http://dx.doi.org/10.1038/s41598-018-20899-9. Dan Bi Lee …

  33. Ab initio electron density determination directly from solution scattering data

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    29 Jan 2018 | BioXFEL Publications | Contributor(s): Thomas D Grant

    http://dx.doi.org/10.1038/nmeth.4581 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Grant, T.D., 2018. Ab initio electron density determination directly from solution scattering data. Nature Methods. Available at: http://dx.doi.org/10.1038/nmeth.4581. Thomas D Grant

  34. Femtosecond X-ray diffraction from an aerosolized beam of protein nanocrystals

    0.0 out of 5 stars 

    26 Jan 2018 | BioXFEL Publications | Contributor(s): Salah Awel, Richard Kirian, Max Oliver Wiedorn, Kenneth R. Beyerlein, Nils Roth, Daniel A. Horke, Dominik Oberthür, Juraj Knoska, Valerio Mariani, Andrew Morgan, Luigi Adriano, Alexandra Tolstikova, P. Lourdu Xavier, Oleksandr Yefanov, Andrew Aquila, Anton Barty, Shatabdi Roy-Chowdhury, Mark S. Hunter, Daniel James, Joseph S. Robinson, Uwe Weierstall, Andrei V. Rode, Saša Bajt, Jochen Küpper, Henry Chapman

    http://dx.doi.org/10.1107/s1600576717018131 High-resolution Bragg diffraction from aerosolized single granulovirus nanocrystals using an X-ray free-electron laser is demonstrated. The outer dimensions of the in-vacuum aerosol injector components are identical to conventional liquid-microjet nozzles …

  35. qFit-ligand reveals widespread conformational heterogeneity of drug-like molecules in X-ray electron density maps

    0.0 out of 5 stars 

    26 Jan 2018 | BioXFEL Publications | Contributor(s): Gydo CP Van Zundert, Brandi M Hudson, Daniel A Keedy, Rasmus Fonseca, Amelie Heliou, Pooja Suresh, Kenneth Borrelli, Tyler Day, James Fraser, Henry Van Den Bedem

    http://dx.doi.org/10.1101/253419 Proteins and ligands sample a conformational ensemble that governs molecular recognition, activity, and dissociation. In structure-based drug design, access to this conformational ensemble is critical to understand the balance between entropy and enthalpy in lead …

  36. Transferring the entatic-state principle to copper photochemistry

    0.0 out of 5 stars 

    15 Jan 2018 | BioXFEL Publications | Contributor(s): B. Dicke, A. Hoffmann, J. Stanek, M. S. Rampp, B. Grimm-Lebsanft, F. Biebl, D. Rukser, B. Maerz, D. Göries, M. Naumova, M. Biednov, G. Neuber, A. Wetzel, S. M. Hofmann, P. Roedig, A. Meents, J. Bielecki, J. Andreasson, K. R. Beyerlein, H. N. Chapman, C. Bressler, W. Zinth, M. Rübhausen, S. Herres-Pawlis

    http://dx.doi.org/10.1038/nchem.2916 journal-article Dicke, B. et al., 2018. Transferring the entatic-state principle to copper photochemistry. Nature Chemistry. Available at: http://dx.doi.org/10.1038/nchem.2916. B. Dicke and A. Hoffmann and J. Stanek and M. S. Rampp and B. Grimm-Lebsanft and …

  37. Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor

    0.0 out of 5 stars 

    04 Jan 2018 | BioXFEL Publications | Contributor(s): Tao Che, Susruta Majumdar, Saheem A. Zaidi, Pauline Ondachi, John D. McCorvy, Sheng Wang, Philip D. Mosier, Rajendra Uprety, Eyal Vardy, Brian E. Krumm, Gye Won Han, Ming-Yue Lee, Els Pardon, Jan Steyaert, Xi-Ping Huang, Ryan T. Strachan, Alexandra R. Tribo, Gavril W. Pasternak, F. Ivy Carroll, Raymond C. Stevens, Vadim Cherezov, Vsevolod Katritch, Daniel Wacker, Bryan L. Roth

    http://dx.doi.org/10.1016/j.cell.2017.12.011 journal-article Che, T. et al., 2018. Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor. Cell, 172(1-2), pp.55–67.e15. Available at: http://dx.doi.org/10.1016/j.cell.2017.12.011. Tao Che and Susruta Majumdar and Saheem …

  38. High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions

    0.0 out of 5 stars 

    04 Jan 2018 | BioXFEL Publications | Contributor(s): Jana Broecker, Takefumi Morizumi, Wei-Lin Ou, Viviane Klingel, Anling Kuo, David J Kissick, Andrii Ishchenko, Ming-Yue Lee, Shenglan Xu, Oleg Makarov, Vadim Cherezov, Craig M Ogata, Oliver P Ernst

    http://dx.doi.org/10.1038/nprot.2017.135 journal-article Broecker, J. et al., 2018. High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions. Nature Protocols, 13(2), pp.260–292. Available at: …

  39. Thermal x-ray diffraction and near-field phase contrast imaging

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    27 Dec 2017 | BioXFEL Publications | Contributor(s): Zheng Li, Anton Classen, Tao Peng, Nikita Medvedev, Fenglin Wang, Henry Chapman, Yanhua Shih

    http://dx.doi.org/10.1209/0295-5075/120/16003 journal-article Li, Z. et al., 2017. Thermal x-ray diffraction and near-field phase contrast imaging. EPL (Europhysics Letters), 120(1), p.16003. Available at: http://dx.doi.org/10.1209/0295-5075/120/16003. Zheng Li and Anton Classen and Tao Peng and …

  40. Resolution extension by image summing in serial femtosecond crystallography of two-dimensional membrane-protein crystals

    0.0 out of 5 stars 

    22 Dec 2017 | BioXFEL Publications | Contributor(s): Cecilia M. Casadei, Ching-Ju Tsai, Anton Barty, Mark S. Hunter, Nadia Zatsepin, Celestino Padeste, Guido Capitani, W. Henry Benner, Sébastien Boutet, Stefan Hau-Riege, Christopher Kupitz, Marc Messerschmidt, John I. Ogren, Tom Pardini, Kenneth J. Rothschild, Leonardo Sala, Brent W. Segelke, Garth J. Williams, James E. Evans, Xiao-Dan Li, Matthew Coleman, Bill Pedrini, Matthias Frank

    http://dx.doi.org/10.1107/s2052252517017043 Previous proof-of-concept measurements on single-layer two-dimensional membrane-protein crystals performed at X-ray free-electron lasers (FELs) have demonstrated that the collection of meaningful diffraction patterns, which is not possible at synchrotrons …

  41. Resolution extension by image summing in serial femtosecond crystallography of two-dimensional membrane-protein crystals

    0.0 out of 5 stars 

    22 Dec 2017 | BioXFEL Publications | Contributor(s): Cecilia M. Casadei, Ching-Ju Tsai, Anton Barty, Mark S. Hunter, Nadia Zatsepin, Celestino Padeste, Guido Capitani, W. Henry Benner, Sébastien Boutet, Stefan Hau-Riege, Christopher Kupitz, Marc Messerschmidt, John I. Ogren, Tom Pardini, Kenneth J. Rothschild, Leonardo Sala, Brent W. Segelke, Garth J. Williams, James E. Evans, Xiao-Dan Li, Matthew Coleman, Bill Pedrini, Matthias Frank

    http://dx.doi.org/10.1107/s2052252517017043/ec5006sup1.pdf component Casadei, C.M. et al., 2018. Resolution extension by image summing in serial femtosecond crystallography of two-dimensional membrane-protein crystals. Available at: http://dx.doi.org/10.1107/s2052252517017043/ec5006sup1.pdf. …

  42. Small-angle X-ray and neutron scattering demonstrates that cell-free expression produces properly formed disc-shaped nanolipoprotein particles

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    20 Dec 2017 | BioXFEL Publications | Contributor(s): Thomas E. Cleveland, Wei He, Angela C. Evans, Nicholas O. Fischer, Edmond Y. Lau, Matthew Coleman, Paul Butler

    http://dx.doi.org/10.1002/pro.3365 journal-article Cleveland, T.E. et al., 2017. Small-angle X-ray and neutron scattering demonstrates that cell-free expression produces properly formed disc-shaped nanolipoprotein particles. Protein Science. Available at: http://dx.doi.org/10.1002/pro.3365. …

  43. Time-resolved mixing-jet X-ray free-electron laser crystallography experiments

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    19 Dec 2017 | BioXFEL Publications | Contributor(s): Dominik Oberthuer, Juraj Knoška, Max Oliver Wiedorn, Saša Bajt, Henry Chapman

    http://dx.doi.org/10.1107/s2053273317087393 journal-article Oberthuer, D. et al., 2017. Time-resolved mixing-jet X-ray free-electron laser crystallography experiments. Acta Crystallographica Section A Foundations and Advances, 73(a2), pp.C835–C835. Available at: …

  44. Picosecond to microsecond TR-XAS: intermediates in the photolysis of methylcobalamin

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    19 Dec 2017 | BioXFEL Publications | Contributor(s): GANESH SUBRAMANIAN, Gerdenis Kodis, Andrew Chizmeshya, Qingyu Kong, Xiaoyi Zhang, Uwe Weierstall, John Spence

    http://dx.doi.org/10.1107/s2053273317084455 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Subramanian, G. et al., 2017. Picosecond to microsecond TR-XAS: intermediates in the photolysis of methylcobalamin. Acta Crystallographica Section A Foundations and Advances, 73(a2), …

  45. Mechanism and X-ray damage: beware of artefacts in xylose isomerase

    0.0 out of 5 stars 

    19 Dec 2017 | BioXFEL Publications | Contributor(s): Helena Taberman, Charles S. Bury, Kristin A. Sutton, Edward Snell, Elspeth F. Garman

    http://dx.doi.org/10.1107/s205327331709341x journal-article Taberman, H. et al., 2017. Mechanism and X-ray damage: beware of artefacts in xylose isomerase. Acta Crystallographica Section A Foundations and Advances, 73(a2), pp.C232–C232. Available at: …

  46. Monochromatic and polychromatic serial crystallography at the Advanced Photon Source

    0.0 out of 5 stars 

    19 Dec 2017 | BioXFEL Publications | Contributor(s): R. F. Fischetti, J. Martin-Garcia, N. Zatsepin, N. Stander, L. Zhu, G. Subramanian, G. Nelson, J. Coe, N. Nagaratnam, S. Roy-Chowdury, D. Kissick, A. Ishchenko, C. Conrad, G. Ketawala, D. James, J. Zook, C. Ogata, N. Venugopalan, S. Xu, A. Meents, V. Srajer, R. Henning, H. Chapman, J. Spence, U. Weierstall, V. Cherezov, P. Fromme, W. Liu

    http://dx.doi.org/10.1107/s0108767317096404 journal-article Fischetti, R.F. et al., 2017. Monochromatic and polychromatic serial crystallography at the Advanced Photon Source. Acta Crystallographica Section A Foundations and Advances, 73(a1), pp.a368–a369. Available at: …

  47. Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography

    0.0 out of 5 stars 

    19 Dec 2017 | BioXFEL Publications | Contributor(s): J. R. Stagno, Y. Liu, Y. R. Bhandari, C. E. Conrad, S. Panja, M. Swain, L. Fan, G. Nelson, C. Li, D. R. Wendel, T. A. White, J. D. Coe, M. O. Wiedorn, J. Knoska, D. Oberthuer, R. A. Tuckey, P. Yu, M. Dyba, S. G. Tarasov, U. Weierstall, T. D. Grant, C. D. Schwieters, J. Zhang, A. R. Ferré-D'Amaré, P. Fromme, D. E. Draper, M. Liang, M. S. Hunter, S. Boutet, K. Tan, X. Zuo, X. Ji, A. Barty, N. A. Zatsepin, H. N. Chapman, J. C. H. Spence, S. A. Woodson, Y.-X. Wang

    http://dx.doi.org/10.1107/s0108767317099081 journal-article Stagno, J.R. et al., 2017. Structures of riboswitch RNA reaction states by mix-and-inject XFEL serial crystallography. Acta Crystallographica Section A Foundations and Advances, 73(a1), pp.a92–a92. Available at: …

  48. Low-background pink-beam serial crystallography

    0.0 out of 5 stars 

    19 Dec 2017 | BioXFEL Publications | Contributor(s): A. Meents, M. O. Wiedorn, V. Srajer, R. Henning, I. Sarrou, J. Bergtholdt, M. Barthelmess, P. Reinke, D. Dierksmeyer, A. Tolstikova, S. Schaible, M. Messerschmidt, C. M. Ogata, D. J. Kissick, M. Taft, D. Manstein, J. Lieske, D. Oberthuer, R. F. Fischetti, H. N. Chapman

    http://dx.doi.org/10.1107/s0108767317096052 journal-article Meents, A. et al., 2017. Low-background pink-beam serial crystallography. Acta Crystallographica Section A Foundations and Advances, 73(a1), pp.a405–a405. Available at: http://dx.doi.org/10.1107/s0108767317096052. A. Meents and M. O. …

  49. Atomic structure of granulin determined from native nanocrystalline granulovirus using an X-ray free-electron laser

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    19 Dec 2017 | BioXFEL Publications | Contributor(s): Cornelius Gati, Dominik Oberthuer, Oleksandr Yefanov, Richard D. Bunker, Peter Metcalf, Anton Barty, Henry Chapman

    http://dx.doi.org/10.1107/s0108767317097124 journal-article Gati, C. et al., 2017. Atomic structure of granulin determined from native nanocrystalline granulovirus using an X-ray free-electron laser. Acta Crystallographica Section A Foundations and Advances, 73(a1), pp.a292–a293. Available at: …

  50. Phase-retrieval algorithms for direct phasing of coherent nanocrystal diffraction

    0.0 out of 5 stars 

    19 Dec 2017 | BioXFEL Publications | Contributor(s): Joe Chen, Richard Kirian

    http://dx.doi.org/10.1107/s0108767317097653 journal-article Chen, J.P.J. & Kirian, R.A., 2017. Phase-retrieval algorithms for direct phasing of coherent nanocrystal diffraction. Acta Crystallographica Section A Foundations and Advances, 73(a1), pp.a239–a239. Available at: …

  51. XFEL structures of the influenza M2 proton channel at 1.4 Å: room-temperature water networks and insights into proton conduction

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    19 Dec 2017 | BioXFEL Publications | Contributor(s): Jessica L. Thomaston, Rahel Woldeyes, Takanori Nakane, Kotaro Koiwai, Ayumi Yamashita, Tomoyuki Tanaka, Toshi Arima, Jun Kobayashi, Tetsuya Masuda, Mamoru Suzuki, Michihiro Sugahara, Rie Tanaka, Eriko Nango, So Iwata, Fumiaki Yumoto, James Fraser, William F. DeGrado

    http://dx.doi.org/10.1107/s0108767317099603 journal-article Thomaston, J.L. et al., 2017. XFEL structures of the influenza M2 proton channel at 1.4 Å: room-temperature water networks and insights into proton conduction. Acta Crystallographica Section A Foundations and Advances, 73(a1), …

  52. The influence of promiscuous metals on metalloprotein structure: complementary techniques to separate the good, the bad and the ugly

    0.0 out of 5 stars 

    19 Dec 2017 | BioXFEL Publications | Contributor(s): Edward Snell, M. Elizabeth Snell, Oliver B. Zeldin, Geoffrey W. Grime, Elspeth F. Garman

    http://dx.doi.org/10.1107/s0108767317097677 journal-article Snell, E.H. et al., 2017. The influence of promiscuous metals on metalloprotein structure: complementary techniques to separate the good, the bad and the ugly. Acta Crystallographica Section A Foundations and Advances, 73(a1), …

  53. Structural changes of tailless bacteriophage ΦX174 during penetration of bacterial cell walls

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    11 Dec 2017 | BioXFEL Publications | Contributor(s): Yingyuan Sun, Aaron P. Roznowski, Joshua M. Tokuda, Thomas Klose, Alexander Mauney, Lois Pollack, Bentley A. Fane, Michael G. Rossmann

    http://dx.doi.org/10.1073/pnas.1716614114 journal-article Sun, Y. et al., 2017. Structural changes of tailless bacteriophage ΦX174 during penetration of bacterial cell walls. Proceedings of the National Academy of Sciences, p.201716614. Available at: http://dx.doi.org/10.1073/pnas.1716614114. …

  54. 5th BioXFEL International Conference

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    04 Dec 2017 | Downloads

    …

  55. EuXFEL Workshop

    0.0 out of 5 stars 

    30 Nov 2017 | Downloads

    …

  56. Publisher's Note: “Enzyme transient state kinetics in crystal and solution from the perspective of a time-resolved crystallographer” [Struct. Dyn. 1, 024701 (2014)]

    0.0 out of 5 stars 

    28 Nov 2017 | BioXFEL Publications | Contributor(s): Marius Schmidt, Dilano Saldin

    http://dx.doi.org/10.1063/1.5016802 journal-article Schmidt, M. & Saldin, D.K., 2017. Publisher’s Note: “Enzyme transient state kinetics in crystal and solution from the perspective of a time-resolved crystallographer” [Struct. Dyn. 1, 024701 (2014)]. Structural Dynamics, 4(6), p.069901. …

  57. New routes for PTP1B allosteric inhibition by multitemperature crystallography, fragment screening and covalent tethering

    0.0 out of 5 stars 

    14 Nov 2017 | BioXFEL Publications | Contributor(s): Daniel A Keedy, Zachary B Hill, Justin T Biel, Emily Kang, T. Justin Rettenmaier, Jose Brandao-Neto, Nicholas M Pearce, Frank Von Delft, James A. Wells, James Fraser

    http://dx.doi.org/10.1101/218966 Allostery is an inherent feature of proteins and provides alternative routes to regulating function. Small-molecule allosteric inhibitors are often desirable; however, it remains challenging to identify surface sites in proteins which can bind small molecules and …

  58. Single-Walled Carbon Nanotubes Probed with Insulator-Based Dielectrophoresis

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    13 Nov 2017 | BioXFEL Publications | Contributor(s): Mohammad Towshif Rabbani, Christoph F. Schmidt, Alexandra Ros

    http://dx.doi.org/10.1021/acs.analchem.7b03105 journal-article Rabbani, M.T., Schmidt, C.F. & Ros, A., 2017. Single-Walled Carbon Nanotubes Probed with Insulator-Based Dielectrophoresis. Analytical Chemistry, 89(24), pp.13235–13244. Available at: http://dx.doi.org/10.1021/acs.analchem.7b03105. …

  59. A peak-finding algorithm based on robust statistical analysis in serial crystallography

    0.0 out of 5 stars 

    03 Nov 2017 | BioXFEL Publications | Contributor(s): Marjan Hadian-Jazi, Marc Messerschmidt, Connie Darmanin, Klaus Giewekemeyer, Adrian P. Mancuso, Brian Abbey

    http://dx.doi.org/10.1107/s1600576717014340 The recent development of serial crystallography at synchrotron and X-ray free-electron laser (XFEL) sources is producing crystallographic datasets of ever increasing volume. The size of these datasets is such that fast and efficient analysis presents a …

  60. Revealing Accessibility of Cryptic Protein Binding Sites within the Functional Collagen Fibril

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    01 Nov 2017 | BioXFEL Publications | Contributor(s): Cody Hoop, Jie Zhu, Ana Nunes, David Case, Jean Baum

    http://dx.doi.org/10.3390/biom7040076 journal-article Hoop, C. et al., 2017. Revealing Accessibility of Cryptic Protein Binding Sites within the Functional Collagen Fibril. Biomolecules, 7(4), p.76. Available at: http://dx.doi.org/10.3390/biom7040076. Cody Hoop and Jie Zhu and Ana Nunes and …

  61. Pink-beam serial crystallography

    0.0 out of 5 stars 

    30 Oct 2017 | BioXFEL Publications | Contributor(s): A. Meents, M. O. Wiedorn, V. Srajer, R. Henning, I. Sarrou, J. Bergtholdt, M. Barthelmess, P. Y. A. Reinke, D. Dierksmeyer, A. Tolstikova, S. Schaible, M. Messerschmidt, C. M. Ogata, D. J. Kissick, M. H. Taft, D. J. Manstein, J. Lieske, D. Oberthuer, R. F. Fischetti, H. N. Chapman

    http://dx.doi.org/10.1038/s41467-017-01417-3 journal-article Meents, A. et al., 2017. Pink-beam serial crystallography. Nature Communications, 8(1). Available at: http://dx.doi.org/10.1038/s41467-017-01417-3. A. Meents and M. O. Wiedorn and V. Srajer and R. Henning and I. Sarrou and J. …

  62. Performance of silicon drift detectors at LCLS

    0.0 out of 5 stars 

    25 Oct 2017 | BioXFEL Publications | Contributor(s): G. Blaj, C. J. Kenney, S. Boutet, G. Carini, M. Chollet, G. Dakovski, G. Haller, P. Hart, S. Herrmann, J. Koglin, M. Messerschmidt, S. Nelson, J. Pines, S. Song, J. Thayer, A. Tomada, G. Williams

    http://dx.doi.org/10.1109/nssmic.2016.8069827 proceedings-article Blaj, G. et al., 2016. Performance of silicon drift detectors at LCLS. 2016 IEEE Nuclear Science Symposium, Medical Imaging Conference and Room-Temperature Semiconductor Detector Workshop (NSS/MIC/RTSD). Available at: …

  63. Corrigendum: Diffraction data of core-shell nanoparticles from an X-ray free electron laser

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    24 Oct 2017 | BioXFEL Publications | Contributor(s): Xuanxuan Li, Chun-Ya Chiu, Hsiang-Ju Wang, Stephan Kassemeyer, Sabine Botha, Robert L Shoeman, Robert M Lawrence, Christopher Kupitz, Richard Kirian, Daniel James, Dingjie Wang, Garrett Charles Nelson, Marc Messerschmidt, Sébastien Boutet, Garth J Williams, Elisabeth Hartmann, Aliakbar Jafarpour, Lutz M Foucar, Anton Barty, Henry Chapman, Mengning Liang, Andreas Menzel, Fenglin Wang, Shibom Basu, Raimund Fromme, R.Bruce Doak, Petra Fromme, Uwe Weierstall, Michael H Huang, John Spence, Ilme Schlichting, Brenda Hogue, Haiguang Liu

    http://dx.doi.org/10.1038/sdata.2017.154 journal-article Li, X. et al., 2017. Corrigendum: Diffraction data of core-shell nanoparticles from an X-ray free electron laser. Scientific Data, 4, p.170154. Available at: http://dx.doi.org/10.1038/sdata.2017.154. Xuanxuan Li and Chun-Ya Chiu and …

  64. Analysis of XFEL serial diffraction data from individual crystalline fibrils

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    20 Oct 2017 | BioXFEL Publications | Contributor(s): David H. Wojtas, Kartik Ayyer, Mengning Liang, Estelle Mossou, Filippo Romoli, Carolin Seuring, Kenneth R. Beyerlein, Richard J. Bean, Andrew J. Morgan, Dominik Oberthuer, Holger Fleckenstein, Michael Heymann, Cornelius Gati, Oleksandr Yefanov, Miriam Barthelmess, Eirini Ornithopoulou, Lorenzo Galli, P. Lourdu Xavier, Wai Li Ling, Matthias Frank, Chun Hong Yoon, Thomas A. White, Saša Bajt, Anna Mitraki, Sebastien Boutet, Andrew Aquila, Anton Barty, V. Trevor Forsyth, Henry Chapman, Rick P. Millane

    http://dx.doi.org/10.1107/s2052252517014324 Serial diffraction data collected at the Linac Coherent Light Source from crystalline amyloid fibrils delivered in a liquid jet show that the fibrils are well oriented in the jet. At low fibril concentrations, diffraction patterns are recorded from single …

  65. FBXW8-dependent degradation of MRFAP1 in anaphase controls mitotic cell death

    0.0 out of 5 stars 

    16 Oct 2017 | BioXFEL Publications | Contributor(s): Duan-Zhuo Li, Shun-Fang Liu, Lan Zhu, Yu-Xing Wang, Yi-Xiang Chen, Jie Liu, Gang Hu, Xin Yu, Jian Li, Jin Zhang, Zhi-Xiang Wu, Han Lu, Wei Liu, Bin Liu

    http://dx.doi.org/10.18632/oncotarget.21843 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Li, D.-Z. et al., 2017. FBXW8-dependent degradation of MRFAP1 in anaphase controls mitotic cell death. Oncotarget, 8(57). Available at: http://dx.doi.org/10.18632/oncotarget.21843. …

  66. Post-sample aperture for low background diffraction experiments at X-ray free-electron lasers

    0.0 out of 5 stars 

    16 Oct 2017 | BioXFEL Publications | Contributor(s): Max Oliver Wiedorn, Salah Awel, Andrew J. Morgan, Miriam Barthelmess, Richard Bean, Kenneth R. Beyerlein, Leonard M. G. Chavas, Niko Eckerskorn, Holger Fleckenstein, Michael Heymann, Daniel A. Horke, Juraj Knoška, Valerio Mariani, Dominik Oberthür, Nils Roth, Oleksandr Yefanov, Anton Barty, Saša Bajt, Jochen Küpper, Andrei V. Rode, Richard Kirian, Henry Chapman

    http://dx.doi.org/10.1107/s1600577517011961 The success of diffraction experiments from weakly scattering samples strongly depends on achieving an optimal signal-to-noise ratio. This is particularly important in single-particle imaging experiments where diffraction signals are typically very weak …

  67. Enzyme Intermediates Captured "on-the-fly" by Mix-and-Inject Serial Crystallography

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    13 Oct 2017 | BioXFEL Publications | Contributor(s): Jose Olmos, Suraj Pandey, Jose M. Martin-Garcia, George Douglas Calvey, Andrea Katz, Juray Knoska, Christopher Kupitz, Mark S. Hunter, Mengning Liang, Dominik Oberthuer, Oleksandr Yefanov, Max Oliver Wiedorn, Michael Heymann, Mark Holl, Kanupriya Pande, Anton Barty, Mitchell Miller, Stephan Stern, Shatabdi Roy-Chowdhury, Jesse David Coe, Nirupa Nagaratnam, James D Zook, Jacob Christopher Verburgt, Tyler Norwood, Ishwor Poudyal, David Xu, Jason Koglin, Matt Seaberg, Yun Zhao, Sasa Bajt, Thomas Grant, Valerio Mariani, Garrett Charles Nelson, GANESH SUBRAMANIAN, Euiyoung Bae, Raimund Fromme, Russel Fung, Peter Schwander, Matthias Frank, Thomas White, Uwe Weierstall, Nadia Zatsepin, John Spence, Petra Fromme, Henry Chapman, Lois Pollack, Lee Tremblay, Abbas Ourmazd, George Phillips, Marius Schmidt

    http://dx.doi.org/10.1101/202432 Ever since the first atomic structure of an enzyme was solved, the discovery of the mechanism and dynamics of reactions catalyzed by biomolecules has been the key goal for the understanding of the molecular processes that drive life on earth. Despite a large number …

  68. Correlations in Scattered X-Ray Laser Pulses Reveal Nanoscale Structural Features of Viruses

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    12 Oct 2017 | BioXFEL Publications | Contributor(s): Ruslan P. Kurta, Jeffrey J. Donatelli, Chun Hong Yoon, Peter Berntsen, Johan Bielecki, Benedikt J. Daurer, Hasan Demirci, Petra Fromme, Max Felix Hantke, Filipe R. N. C. Maia, Anna Munke, Carl Nettelblad, Kanupriya Pande, Hemanth K. N. Reddy, Jonas A. Sellberg, Raymond G. Sierra, Martin Svenda, Gijs Van Der Schot, Ivan A. Vartanyants, Garth J. Williams, P. Lourdu Xavier, Andrew Aquila, Peter H. Zwart, Adrian P. Mancuso

    http://dx.doi.org/10.1103/physrevlett.119.158102 journal-article Kurta, R.P. et al., 2017. Correlations in Scattered X-Ray Laser Pulses Reveal Nanoscale Structural Features of Viruses. Physical Review Letters, 119(15). Available at: http://dx.doi.org/10.1103/physrevlett.119.158102. Ruslan P. …

  69. Optimal Pulse Processing, Pile-Up Decomposition, and Applications of Silicon Drift Detectors at LCLS

    0.0 out of 5 stars 

    11 Oct 2017 | BioXFEL Publications | Contributor(s): G. Blaj, C. J. Kenney, A. Dragone, G. Carini, S. Herrmann, P. Hart, A. Tomada, J. Koglin, G. Haller, S. Boutet, M. Messerschmidt, G. Williams, M. Chollet, G. Dakovski, S. Nelson, J. Pines, S. Song, J. Thayer

    http://dx.doi.org/10.1109/tns.2017.2762281 journal-article Blaj, G. et al., 2017. Optimal Pulse Processing, Pile-Up Decomposition, and Applications of Silicon Drift Detectors at LCLS. IEEE Transactions on Nuclear Science, 64(11), pp.2854–2868. Available at: …

  70. Mix-and-diffuse serial synchrotron crystallography

    0.0 out of 5 stars 

    09 Oct 2017 | BioXFEL Publications | Contributor(s): Kenneth R. Beyerlein, Dennis Dierksmeyer, Valerio Mariani, Manuela Kuhn, Iosifina Sarrou, Angelica Ottaviano, Salah Awel, Juraj Knoska, Silje Fuglerud, Olof Jönsson, Stephan Stern, Max Oliver Wiedorn, Oleksandr Yefanov, Luigi Adriano, Richard Bean, Anja Burkhardt, Pontus Fischer, Michael Heymann, Daniel A. Horke, Katharina E. J. Jungnickel, Elena Kovaleva, Olga Lorbeer, Markus Metz, Jan Meyer, Andrew Morgan, Kanupriya Pande, Saravanan Panneerselvam, Carolin Seuring, Aleksandra Tolstikova, Julia Lieske, Steve Aplin, Manfred Roessle, Thomas A. White, Henry Chapman, Alke Meents, Dominik Oberthuer

    http://dx.doi.org/10.1107/s2052252517013124 Unravelling the interaction of biological macromolecules with ligands and substrates at high spatial and temporal resolution remains a major challenge in structural biology. The development of serial crystallography methods at X-ray free-electron lasers …

  71. Nanocrystallography measurements of early stage synthetic malaria pigment

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    28 Sep 2017 | BioXFEL Publications | Contributor(s): Ruben A. Dilanian, Victor Streltsov, Hannah D. Coughlan, Harry M. Quiney, Andrew V. Martin, Nectarios Klonis, Con Dogovski, Sébastien Boutet, Marc Messerschmidt, Garth J. Williams, Sophie Williams, Nicholas W. Phillips, Keith A. Nugent, Leann Tilley, Brian Abbey

    http://dx.doi.org/10.1107/s1600576717012663 The recent availability of extremely intense, femtosecond X-ray free-electron laser (XFEL) sources has spurred the development of serial femtosecond nanocrystallography (SFX). Here, SFX is used to analyze nanoscale crystals of β-hematin, the synthetic …

  72. Merging single-shot XFEL diffraction data from inorganic nanoparticles: a new approach to size and orientation determination

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    22 Sep 2017 | BioXFEL Publications | Contributor(s): Xuanxuan Li, John Spence, Brenda Hogue, Haiguang Liu

    http://dx.doi.org/10.1107/s2052252517012398 X-ray free-electron lasers (XFELs) provide new opportunities for structure determination of biomolecules, viruses and nanomaterials. With unprecedented peak brilliance and ultra-short pulse duration, XFELs can tolerate higher X-ray doses by exploiting the …

  73. Structure determination based on continuous diffraction from macromolecular crystals

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    14 Sep 2017 | BioXFEL Publications | Contributor(s): Henry Chapman, Petra Fromme

    http://dx.doi.org/10.1016/j.sbi.2017.07.008 journal-article Chapman, H.N. & Fromme, P., 2017. Structure determination based on continuous diffraction from macromolecular crystals. Current Opinion in Structural Biology, 45, pp.170–177. Available at: http://dx.doi.org/10.1016/j.sbi.2017.07.008. …

  74. Phase retrieval in the presence of multiplicative noise

    0.0 out of 5 stars 

    06 Sep 2017 | BioXFEL Publications | Contributor(s): Joe Chen, Richard Kirian

    http://dx.doi.org/10.1117/12.2275182 proceedings-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Chen, J.P.J. & Kirian, R.A., 2017. Phase retrieval in the presence of multiplicative noise J. J. Dolne & R. P. Millane, eds. Unconventional and Indirect Imaging, Image Reconstruction, and …

  75. Rescue of Conformational Dynamics in Enzyme Catalysis by Directed Evolution

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    06 Sep 2017 | BioXFEL Publications | Contributor(s): Renee Otten, Lin Liu, Lillian R. Kenner, Michael W. Clarkson, David Mavor, Dan S. Tawfik, Dorothee Kern, James Fraser

    http://dx.doi.org/10.1101/185009 Rational design and directed evolution have proved to be successful approaches to increase catalytic efficiencies of both natural and artificial enzymes. However, a comprehensive understanding of how evolution shapes the energy landscape of catalysis remains a …

  76. XFEL structures of the influenza M2 proton channel: Room temperature water networks and insights into proton conduction

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    23 Aug 2017 | BioXFEL Publications | Contributor(s): Jessica L. Thomaston, Rahel Woldeyes, Takanori Nakane, Ayumi Yamashita, Tomoyuki Tanaka, Kotaro Koiwai, Aaron S. Brewster, Benjamin A. Barad, Yujie Chen, Thomas Lemmin, Monarin Uervirojnangkoorn, Toshi Arima, Jun Kobayashi, Tetsuya Masuda, Mamoru Suzuki, Michihiro Sugahara, Nicholas K. Sauter, Rie Tanaka, Osamu Nureki, Kensuke Tono, Yasumasa Joti, Eriko Nango, So Iwata, Fumiaki Yumoto, James Fraser, William F. DeGrado

    http://dx.doi.org/10.1073/pnas.1705624114 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Thomaston, J.L. et al., 2017. XFEL structures of the influenza M2 proton channel: Room temperature water networks and insights into proton conduction. Proceedings of the National Academy of …

  77. Conformational landscape of a virus by single-particle X-ray scattering

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    14 Aug 2017 | BioXFEL Publications | Contributor(s): Ahmad Hosseinizadeh, Ghoncheh Mashayekhi, Jeremy Copperman, Peter Schwander, Ali Dashti, Reyhaneh Sepehr, Russell Fung, Marius Schmidt, Chun Hong Yoon, Brenda Hogue, Garth J Williams, Andrew Aquila, Abbas Ourmazd

    http://dx.doi.org/10.1038/nmeth.4395 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Hosseinizadeh, A. et al., 2017. Conformational landscape of a virus by single-particle X-ray scattering. Nature Methods. Available at: http://dx.doi.org/10.1038/nmeth.4395. Ahmad Hosseinizadeh and …

  78. Incoherent Diffractive Imaging via Intensity Correlations of Hard X Rays

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    31 Jul 2017 | BioXFEL Publications | Contributor(s): Anton Classen, Kartik Ayyer, Henry Chapman, Ralf Röhlsberger, Joachim Von Zanthier

    http://dx.doi.org/10.1103/physrevlett.119.053401 journal-article Classen, A. et al., 2017. Incoherent Diffractive Imaging via Intensity Correlations of Hard X Rays. Physical Review Letters, 119(5). Available at: http://dx.doi.org/10.1103/physrevlett.119.053401. Anton Classen and Kartik Ayyer and …

  79. Allosteric Inhibitors, Crystallography, and Comparative Analysis Reveal Network of Coordinated Movement across Human Herpesvirus Proteases

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    31 Jul 2017 | BioXFEL Publications | Contributor(s): Timothy M. Acker, Jonathan E. Gable, Markus-Frederik Bohn, Priyadarshini Jaishankar, Michael Thompson, James Fraser, Adam R. Renslo, Charles S. Craik

    http://dx.doi.org/10.1021/jacs.7b04030 journal-article Acker, T.M. et al., 2017. Allosteric Inhibitors, Crystallography, and Comparative Analysis Reveal Network of Coordinated Movement across Human Herpesvirus Proteases. Journal of the American Chemical Society. Available at: …

  80. Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors

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    27 Jul 2017 | BioXFEL Publications | Contributor(s): X. Edward Zhou, Yuanzheng He, Parker W. De Waal, Xiang Gao, Yanyong Kang, Ned Van Eps, Yanting Yin, Kuntal Pal, Devrishi Goswami, Thomas A. White, Anton Barty, Naomi R. Latorraca, Henry Chapman, Wayne L. Hubbell, Ron O. Dror, Raymond C. Stevens, Vadim Cherezov, Vsevolod V. Gurevich, Patrick R. Griffin, Oliver P. Ernst, Karsten Melcher, H. Eric Xu

    http://dx.doi.org/10.1016/j.cell.2017.07.002 journal-article Zhou, X.E. et al., 2017. Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors. Cell, 170(3), pp.457–469.e13. Available at: http://dx.doi.org/10.1016/j.cell.2017.07.002. X. Edward Zhou and …

  81. Cell-free production of a functional oligomeric form of aChlamydiamajor outer-membrane protein (MOMP) for vaccine development

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    24 Jul 2017 | BioXFEL Publications | Contributor(s): Wei He, Martina Felderman, Angela C. Evans, Jia Geng, David Homan, Feliza Bourguet, Nicholas O. Fischer, Yuanpei Li, Kit S. Lam, Aleksandr Noy, Li Xing, R. Holland Cheng, Amy Rasley, Craig D. Blanchette, Kurt Kamrud, Nathaniel Wang, Heather Gouvis, Todd C. Peterson, Bolyn Hubby, Matthew Coleman

    http://dx.doi.org/10.1074/jbc.m117.784561 journal-article He, W. et al., 2017. Cell-free production of a functional oligomeric form of aChlamydiamajor outer-membrane protein (MOMP) for vaccine development. Journal of Biological Chemistry, 292(36), pp.15121–15132. Available at: …

  82. Development of a ceramic injection molding process for liquid jet nozzles to be applied for X-ray free-electron lasers

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    24 Jul 2017 | BioXFEL Publications | Contributor(s): Volker Piotter, Alexander Klein, Klaus Plewa, Kenneth R. Beyerlein, Henry Chapman, Saša Bajt

    http://dx.doi.org/10.1007/s00542-017-3493-7 journal-article Piotter, V. et al., 2017. Development of a ceramic injection molding process for liquid jet nozzles to be applied for X-ray free-electron lasers. Microsystem Technologies. Available at: http://dx.doi.org/10.1007/s00542-017-3493-7. …

  83. A Bright Future for Serial Femtosecond Crystallography with XFELs

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    18 Jul 2017 | BioXFEL Publications | Contributor(s): Linda C. Johansson, Benjamin Stauch, Andrii Ishchenko, Vadim Cherezov

    http://dx.doi.org/10.1016/j.tibs.2017.06.007 journal-article Johansson, L.C. et al., 2017. A Bright Future for Serial Femtosecond Crystallography with XFELs. Trends in Biochemical Sciences. Available at: http://dx.doi.org/10.1016/j.tibs.2017.06.007. Linda C. Johansson and Benjamin Stauch and …

  84. Single-shot determination of focused FEL wave fields using iterative phase retrieval

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    18 Jul 2017 | BioXFEL Publications | Contributor(s): Masoud Mehrjoo, Klaus Giewekemeyer, Patrik Vagovič, Stephan Stern, Richard Bean, Marc Messerschmidt, Barbara Keitel, Elke Plönjes, Marion Kuhlmann, Tobias Mey, Evgeny A. Schneidmiller, Mikhail V. Yurkov, Torsten Limberg, Adrian P. Mancuso

    http://dx.doi.org/10.1364/oe.25.017892 journal-article Mehrjoo, M. et al., 2017. Single-shot determination of focused FEL wave fields using iterative phase retrieval. Optics Express, 25(15), p.17892. Available at: http://dx.doi.org/10.1364/oe.25.017892. Masoud Mehrjoo and Klaus Giewekemeyer and …

  85. Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody

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    17 Jul 2017 | BioXFEL Publications | Contributor(s): Andrii Ishchenko, Daniel Wacker, Mili Kapoor, Ai Zhang, Gye Won Han, Shibom Basu, Nilkanth N Patel, Marc Messerschmidt, Uwe Weierstall, Wei Liu, Vsevolod Katritch, Bryan L. Roth, Raymond C. Stevens, Vadim Cherezov

    http://dx.doi.org/10.1073/pnas.1700891114 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Ishchenko, A. et al., 2017. Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody. Proceedings of the National Academy of Sciences, …

  86. Crystal structure of CO-bound cytochrome c oxidase determined by serial femtosecond X-ray crystallography at room temperature

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    11 Jul 2017 | BioXFEL Publications | Contributor(s): Izumi Ishigami, Nadia Zatsepin, Masahide Hikita, Chelsie E Conrad, Garrett Charles Nelson, Jesse David Coe, Shibom Basu, Thomas D. Grant, Matthew H. Seaberg, Raymond G. Sierra, Mark S. Hunter, Petra Fromme, Raimund Fromme, Syun-Ru Yeh, Denis L. Rousseau

    http://dx.doi.org/10.1073/pnas.1705628114 Cytochromecoxidase (CcO), the terminal enzyme in the electron transfer chain, translocates protons across the inner mitochondrial membrane by harnessing the free energy generated by the reduction of oxygen to water. Several redox-coupled proton …

  87. FELIX: an algorithm for indexing multiple crystallites in X-ray free-electron laser snapshot diffraction images

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    07 Jul 2017 | BioXFEL Publications | Contributor(s): Kenneth R. Beyerlein, Thomas A. White, Oleksandr Yefanov, Cornelius Gati, Ivan G. Kazantsev, Nicolai Fog-Gade Nielsen, Peter M. Larsen, Henry Chapman, Søren Schmidt

    http://dx.doi.org/10.1107/s1600576717007506 A novel algorithm for indexing multiple crystals in snapshot X-ray diffraction images, especially suited for serial crystallography data, is presented. The algorithm, FELIX, utilizes a generalized parametrization of the Rodrigues–Frank space, in which …

  88. Continuous diffraction of molecules and disordered molecular crystals

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    07 Jul 2017 | BioXFEL Publications | Contributor(s): Henry Chapman, Oleksandr M. Yefanov, Kartik Ayyer, Thomas A. White, Anton Barty, Andrew Morgan, Valerio Mariani, Dominik Oberthuer, Kanupriya Pande

    http://dx.doi.org/10.1107/s160057671700749x The intensities of far-field diffraction patterns of orientationally aligned molecules obey Wilson statistics, whether those molecules are in isolation (giving rise to a continuous diffraction pattern) or arranged in a crystal (giving rise to Bragg …

  89. Watching proteins function with time-resolved x-ray crystallography

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    03 Jul 2017 | BioXFEL Publications | Contributor(s): Vukica Šrajer, Marius Schmidt

    http://dx.doi.org/10.1088/1361-6463/aa7d32 journal-article Šrajer, V. & Schmidt, M., 2017. Watching proteins function with time-resolved x-ray crystallography. Journal of Physics D: Applied Physics, 50(37), p.373001. Available at: http://dx.doi.org/10.1088/1361-6463/aa7d32. Vukica Šrajer and …

  90. How Cubic Can Ice Be?

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    28 Jun 2017 | BioXFEL Publications | Contributor(s): Andrew J. Amaya, Harshad Pathak, Viraj P. Modak, Hartawan Laksmono, N. Duane Loh, Jonas A. Sellberg, Raymond G. Sierra, Trevor A. McQueen, Matt J. Hayes, Garth J. Williams, Marc Messerschmidt, Sébastien Boutet, Michael J. Bogan, Anders Nilsson, Claudiu A. Stan, Barbara E. Wyslouzil

    http://dx.doi.org/10.1021/acs.jpclett.7b01142 journal-article Amaya, A.J. et al., 2017. How Cubic Can Ice Be? The Journal of Physical Chemistry Letters, pp.3216–3222. Available at: http://dx.doi.org/10.1021/acs.jpclett.7b01142. Andrew J. Amaya and Harshad Pathak and Viraj P. Modak and Hartawan …

  91. Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source

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    27 Jun 2017 | BioXFEL Publications | Contributor(s): Hemanth K.N. Reddy, Chun Hong Yoon, Andrew Aquila, Salah Awel, Kartik Ayyer, Anton Barty, Peter Berntsen, Johan Bielecki, Sergey Bobkov, Maximilian Bucher, Gabriella A. Carini, Sebastian Carron, Henry Chapman, Benedikt Daurer, Hasan Demirci, Tomas Ekeberg, Petra Fromme, Janos Hajdu, Max Felix Hanke, Philip Hart, Brenda Hogue, Ahmad Hosseinizadeh, Yoonhee Kim, Richard Kirian, Ruslan P. Kurta, Daniel S.D. Larsson, N. Duane Loh, Filipe R.N.C. Maia, Adrian P. Mancuso, Kerstin Mühlig, Anna Munke, Daewoong Nam, Carl Nettelblad, Abbas Ourmazd, Max Rose, Peter Schwander, Marvin Seibert, Jonas A. Sellberg, Changyong Song, John Spence, Martin Svenda, Gijs Van Der Schot, Ivan A. Vartanyants, Garth J. Williams, P. Lourdu Xavier

    http://dx.doi.org/10.1038/sdata.2017.79 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Reddy, H.K.N. et al., 2017. Coherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source. Scientific Data, 4, p.170079. Available at: …

  92. Algorithm for Reconstruction of 3D Images of Nanorice Particles from Diffraction Patterns of Two Particles in Independent Random Orientations with an X-ray Laser

    0.0 out of 5 stars 

    23 Jun 2017 | BioXFEL Publications | Contributor(s): Sung Soon Kim, Sandi Wibowo, Dilano Saldin

    http://dx.doi.org/10.3390/app7070646 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Kim, S., Wibowo, S. & Saldin, D., 2017. Algorithm for Reconstruction of 3D Images of Nanorice Particles from Diffraction Patterns of Two Particles in Independent Random Orientations with an X-ray …

  93. Critical Role of Water Molecules in Proton Translocation by the Membrane-Bound Transhydrogenase

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    22 Jun 2017 | BioXFEL Publications | Contributor(s): Pius S. Padayatti, Josephine H. Leung, Paween Mahinthichaichan, Emad Tajkhorshid, Andrii Ishchenko, Vadim Cherezov, S. Michael Soltis, J. Baz Jackson, C. David Stout, Robert B. Gennis, Qinghai Zhang

    http://dx.doi.org/10.1016/j.str.2017.05.022 journal-article Padayatti, P.S. et al., 2017. Critical Role of Water Molecules in Proton Translocation by the Membrane-Bound Transhydrogenase. Structure, 25(7), pp.1111–1119.e3. Available at: http://dx.doi.org/10.1016/j.str.2017.05.022. Pius S. …

  94. Non-thermal damage to lead tungstate induced by intense short-wavelength laser radiation (Conference Presentation)

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    21 Jun 2017 | BioXFEL Publications | Contributor(s): Vojtech Vozda, Pavel Boháček, Tomáš Burian, Jaromir Chalupský, Vera Hájková, Libor Juha, Ludek Vyšín, Jérôme Gaudin, Philip A. Heimann, Stefan Hau-Riege, Marek Jurek, Dorota Klinger, Jacek Krzywinski, Marc Messerschmidt, Stefan P. Moeller, Robert Nagler, Jerzy B. Pelka, Michael Rowen, William F. Schlotter, Michele L. Swiggers, Harald Sinn, Ryszard Sobierajski, Kai Tiedtke, Sven Toleikis, Thomas Tschentscher, Joshua J. Turner, Hubertus Wabnitz, Art J. Nelson, Maria V. Kozlova, Sam M. Vinko, Thomas Whitcher, Thomas Dzelzainis, Oldrich Renner, Karel Saksl, Roland R. Fäustlin, Ali R. Khorsand, Marta Fajardo, Bianca S. Iwan, Jakob Andreasson, Janos Hajdu, Nicusor Timneanu, Justin S. Wark, David Riley, Richard W. Lee, Mitsuru Nagasono, Makina Yabashi

    http://dx.doi.org/10.1117/12.2270944 proceedings-article Vozda, V. et al., 2017. Non-thermal damage to lead tungstate induced by intense short-wavelength laser radiation (Conference Presentation) L. Juha, S. Bajt, & R. Soufli, eds. Damage to VUV, EUV, and X-ray Optics VI. Available at: …

  95. Corrigendum: Double-flow focused liquid injector for efficient serial femtosecond crystallography

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    21 Jun 2017 | BioXFEL Publications | Contributor(s): Dominik Oberthuer, Juraj Knoška, Max Oliver Wiedorn, Kenneth R. Beyerlein, David Bushnell, Elena G. Kovaleva, Michael Heymann, Lars Gumprecht, Richard Kirian, Anton Barty, Valerio Mariani, Aleksandra Tolstikova, Luigi Adriano, Salah Awel, Miriam Barthelmess, Katerina Dörner, P. Lourdu Xavier, Oleksandr Yefanov, Daniel R. James, Garrett Charles Nelson, Dingjie Wang, George Douglas Calvey, Yujie Chen, Andrea Schmidt, Michael Szczepek, Stefan Frielingsdorf, Oliver Lenz, Edward Snell, Philip J. Robinson, Božidar Šarler, Grega Belšak, Marjan Maček, Fabian Wilde, Andrew Aquila, Sébastien Boutet, Mengning Liang, Mark S. Hunter, Patrick Scheerer, John D. Lipscomb, Uwe Weierstall, Roger Kornberg, John Spence, Lois Pollack, Henry Chapman, Saša Bajt

    http://dx.doi.org/10.1038/srep46846 journal-article Oberthuer, D. et al., 2017. Corrigendum: Double-flow focused liquid injector for efficient serial femtosecond crystallography. Scientific Reports, 7, p.46846. Available at: http://dx.doi.org/10.1038/srep46846. Dominik Oberthuer and Juraj …

  96. Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV

    0.0 out of 5 stars 

    21 Jun 2017 | BioXFEL Publications | Contributor(s): Yi Zheng, Gye Won Han, Ruben Abagyan, Beili Wu, Raymond C. Stevens, Vadim Cherezov, Irina Kufareva, Tracy M. Handel

    http://dx.doi.org/10.1016/j.immuni.2017.05.002 journal-article Zheng, Y. et al., 2017. Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV. Immunity, 46(6), pp.1005–1017.e5. Available at: …

  97. Synthesis and biochemical characterization of EGF receptor in a water-soluble membrane model system

    0.0 out of 5 stars 

    06 Jun 2017 | BioXFEL Publications | Contributor(s): Tiffany M. Scharadin, Wei He, Yianni Yiannakou, Alexey A. Tomilov, Matthew Saldana, Gino A. Cortopassi, Kermit L. Carraway, Matthew Coleman, Paul T. Henderson

    http://dx.doi.org/10.1371/journal.pone.0177761 journal-article Scharadin, T.M. et al., 2017. Synthesis and biochemical characterization of EGF receptor in a water-soluble membrane model system L. Buday, ed. PLOS ONE, 12(6), p.e0177761. Available at: …

  98. Flow-aligned, single-shot fiber diffraction using a femtosecond X-ray free-electron laser

    0.0 out of 5 stars 

    02 Jun 2017 | BioXFEL Publications | Contributor(s): David Popp, N. Duane Loh, Habiba Zorgati, Umesh Ghoshdastider, Lu Ting Liow, Magdalena I. Ivanova, Mårten Larsson, Daniel P. DePonte, Richard Bean, Kenneth R. Beyerlein, Cornelius Gati, Dominik Oberthuer, David Arnlund, Gisela Brändén, Peter Berntsen, Duilio Cascio, Leonard M. G. Chavas, Joe Chen, Ke Ding, Holger Fleckenstein, Lars Gumprecht, Rajiv Harimoorthy, Estelle Mossou, Michael R. Sawaya, Aaron S. Brewster, Johan Hattne, Nicholas K. Sauter, Marvin Seibert, Carolin Seuring, Francesco Stellato, Thomas Tilp, David S. Eisenberg, Marc Messerschmidt, Garth J. Williams, Jason E. Koglin, Lee Makowski, Rick P. Millane, Trevor Forsyth, Sébastien Boutet, Thomas A. White, Anton Barty, Henry Chapman, Swaine L. Chen, Mengning Liang, Richard Neutze, Robert C. Robinson

    http://dx.doi.org/10.1002/cm.21378 journal-article Popp, D. et al., 2017. Flow-aligned, single-shot fiber diffraction using a femtosecond X-ray free-electron laser. Cytoskeleton. Available at: http://dx.doi.org/10.1002/cm.21378. David Popp and N. Duane Loh and Habiba Zorgati and Umesh …

  99. Outrunning damage: Electrons vs X-rays—timescales and mechanisms

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    01 Jun 2017 | BioXFEL Publications | Contributor(s): John Spence

    http://dx.doi.org/10.1063/1.4984606 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Spence, J.C.H., 2017. Outrunning damage: Electrons vs X-rays—timescales and mechanisms. Structural Dynamics, 4(4), p.044027. Available at: http://dx.doi.org/10.1063/1.4984606. John C. …

  100. Crystallization of Membrane Proteins: An Overview

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    01 Jun 2017 | BioXFEL Publications | Contributor(s): Andrii Ishchenko, Enrique E. Abola, Vadim Cherezov

    http://dx.doi.org/10.1007/978-1-4939-7000-1_5 book-chapter Ishchenko, A., Abola, E.E. & Cherezov, V., 2017. Crystallization of Membrane Proteins: An Overview. Protein Crystallography, pp.117–141. Available at: http://dx.doi.org/10.1007/978-1-4939-7000-1_5. Andrii Ishchenko and Enrique E. Abola …