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  1. The Role of Correlation and Solvation in Ion Interactions with B-DNA

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    19 Jan 2016 | BioXFEL Publications | Contributor(s): Maria L. Sushko, Dennis G. Thomas, Suzette A. Pabit, Lois Pollack, Alexey V. Onufriev, Nathan A. Baker

    journal-article http://dx.doi.org/10.1016/j.bpj.2015.12.011 Sushko, M.L. et al., 2016. The Role of Correlation and Solvation in Ion Interactions with B-DNA. Biophysical Journal, 110(2), pp.315–326. Available at: http://dx.doi.org/10.1016/j.bpj.2015.12.011. Maria L. Sushko and Dennis G. Thomas …

  2. The room temperature crystal structure of a bacterial phytochrome determined by serial femtosecond crystallography

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    19 Oct 2016 | BioXFEL Publications | Contributor(s): Petra Edlund, Heikki Takala, Elin Claesson, Léocadie Henry, Robert Dods, Heli Lehtivuori, Matthijs Panman, Kanupriya Pande, Thomas White, Takanori Nakane, Oskar Berntsson, Emil Gustavsson, Petra Båth, Vaibhav Modi, Shatabdi Roy-Chowdhury, James D Zook, Peter Berntsen, Suraj Pandey, Ishwor Poudyal, Jason Tenboer, Christopher Kupitz, Anton Barty, Petra Fromme, Jake D. Koralek, Tomoyuki Tanaka, John Spence, Mengning Liang, Mark S. Hunter, Sebastien Boutet, Eriko Nango, Keith Moffat, Gerrit Groenhof, Janne Ihalainen, Emina A. Stojković, Marius Schmidt, Sebastian Westenhoff

    http://dx.doi.org/10.1038/srep35279 Petra Edlund and Heikki Takala and Elin Claesson and Léocadie Henry and Robert Dods and Heli Lehtivuori and Matthijs Panman and Kanupriya Pande and Thomas White and Takanori Nakane and Oskar Berntsson and Emil Gustavsson and Petra Båth and Vaibhav Modi and …

  3. The Single Particles, Clusters and Biomolecules and Serial Femtosecond Crystallography instrument of the European XFEL: initial installation

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    12 Apr 2019 | BioXFEL Publications | Contributor(s): Adrian P. Mancuso, Andrew Aquila, Lewis Batchelor, Richard J. Bean, Johan Bielecki, Gannon Borchers, Katerina Doerner, Klaus Giewekemeyer, Rita Graceffa, Oliver D. Kelsey, Yoonhee Kim, Henry J. Kirkwood, Alexis Legrand, Romain Letrun, Bradley Manning, Luis Lopez Morillo, Marc Messerschmidt, Grant Mills, Steffen Raabe, Nadja Reimers, Adam Round, Tokushi Sato, Joachim Schulz, Cedric Signe Takem, Marcin Sikorski, Stephan Stern, Prasad Thute, Patrik Vagovič, Britta Weinhausen, Thomas Tschentscher

    http://dx.doi.org/10.1107/s1600577519003308 The European X-ray Free-Electron Laser (FEL) became the first operational high-repetition-rate hard X-ray FEL with first lasing in May 2017. Biological structure determination has already benefitted from the unique properties and capabilities of X-ray …

  4. The Structural History of RNA Polymerase Transcription Machinery

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    18 Feb 2016 | Teaching Materials | Contributor(s): Roger Kornberg

    Dr. Roger Kornberg, 2006 Nobel Laureate in Chemistry, discusses the structural history of the RNA polymerase II transcription machinery and how it played a role in his successful career.

  5. The structural plasticity of nucleic acid duplexes revealed by WAXS and MD

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    23 Apr 2021 | BioXFEL Publications | Contributor(s): Weiwei He, Yen-Lin Chen, Lois Pollack, Serdal Kirmizialtin

    http://dx.doi.org/10.1126/sciadv.abf6106 Double-stranded DNA (dsDNA) and RNA (dsRNA) helices display an unusual structural diversity. Some structural variations are linked to sequence and may serve as signaling units for protein-binding partners. Therefore, elucidating the mechanisms and factors …

  6. The Structure of the PanD/PanZ Protein Complex Reveals Negative Feedback Regulation of Pantothenate Biosynthesis by Coenzyme A

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    23 Apr 2015 | BioXFEL Publications | Contributor(s): Diana C.F. Monteiro, Vijay Patel, Christopher P. Bartlett, Shingo Nozaki, Thomas D. Grant, James A. Gowdy, Gary S. Thompson, Arnout P. Kalverda, Edward H. Snell, Hironori Niki, Arwen R. Pearson, Michael E. Webb

    http://dx.doi.org/10.1016/j.chembiol.2015.03.017 Diana C.F. Monteiro and Vijay Patel and Christopher P. Bartlett and Shingo Nozaki and Thomas D. Grant and James A. Gowdy and Gary S. Thompson and Arnout P. Kalverda and Edward H. Snell and Hironori Niki and Arwen R. Pearson and Michael E. …

  7. The three-dimensional structure of Drosophila melanogaster (6–4) photolyase at room temperature

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    29 Jul 2021 | BioXFEL Publications | Contributor(s): Andrea Cellini, Weixiao Yuan Wahlgren, Léocadie Henry, Suraj Pandey, Swagatha Ghosh, Leticia Castillon, Elin Claesson, Heikki Takala, Joachim Kübel, Amke Nimmrich, Valentyna Kuznetsova, Eriko Nango, So Iwata, Shigeki Owada, Emina Stojkovic, Marius Schmidt, Janne A. Ihalainen, Sebastian Westenhoff

    http://dx.doi.org/10.1107/s2059798321005830 (6–4) photolyases are flavoproteins that belong to the photolyase/cryptochrome family. Their function is to repair DNA lesions using visible light. Here, crystal structures of Drosophila melanogaster (6–4) photolyase [Dm(6–4)photolyase] at room and …

  8. The use of haptic interfaces and web services in crystallography: an application for a `screen to beam' interface

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    11 Nov 2016 | BioXFEL Publications | Contributor(s): Andrew E. Bruno, Alexei S. Soares, Robin L. Owen, Edward Snell

    http://dx.doi.org/10.1107/s160057671601431x Haptic interfaces have become common in consumer electronics. They enable easy interaction and information entry without the use of a mouse or keyboard. The work presented here illustrates the application of a haptic interface to crystallization screening …

  9. The XBI BioLab for life science experiments at the European XFEL

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    02 Dec 2020 | BioXFEL Publications | Contributor(s): Huijong Han, Ekaterina Round, Robin Schubert, Yasmin Gül, Jana Makroczyová, Domingo Meza, Philipp Heuser, Martin Aepfelbacher, Imrich Barák, Christian Betzel, Petra Fromme, Inari Kursula, Poul Nissen, Elena Tereschenko, Joachim Schulz, Charlotte Uetrecht, Jozef Uličný, Matthias Wilmanns, Janos Hajdu, Victor S. Lamzin, Kristina Lorenzen

    http://dx.doi.org/10.1107/s1600576720013989 The science of X-ray free-electron lasers (XFELs) critically depends on the performance of the X-ray laser and on the quality of the samples placed into the X-ray beam. The stability of biological samples is limited and key biomolecular transformations …

  10. Thermal x-ray diffraction and near-field phase contrast imaging

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    27 Dec 2017 | BioXFEL Publications | Contributor(s): Zheng Li, Anton Classen, Tao Peng, Nikita Medvedev, Fenglin Wang, Henry Chapman, Yanhua Shih

    http://dx.doi.org/10.1209/0295-5075/120/16003 journal-article Li, Z. et al., 2017. Thermal x-ray diffraction and near-field phase contrast imaging. EPL (Europhysics Letters), 120(1), p.16003. Available at: http://dx.doi.org/10.1209/0295-5075/120/16003. Zheng Li and Anton Classen and Tao Peng and …

  11. Three-Dimensional Reconstruction of the Giant Mimivirus Particle with an X-Ray Free-Electron Laser

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    02 Mar 2015 | BioXFEL Publications | Contributor(s): Tomas Ekeberg, Martin Svenda, Chantal Abergel, Filipe R. N. C. Maia, Virginie Seltzer, Jean-Michel Claverie, Max Hantke, Olof Jönsson, Carl Nettelblad, Gijs Van Der Schot, Mengning Liang, Daniel P. DePonte, Anton Barty, M. Marvin Seibert, Bianca Iwan, Inger Andersson, N. Duane Loh, Andrew V. Martin, Henry Chapman, Christoph Bostedt, John D. Bozek, Ken R. Ferguson, Jacek Krzywinski, Sascha W. Epp, Daniel Rolles, Artem Rudenko, Robert Hartmann, Nils Kimmel, Janos Hajdu

    http://dx.doi.org/10.1103/physrevlett.114.098102 Tomas Ekeberg and Martin Svenda and Chantal Abergel and Filipe R. N. C. Maia and Virginie Seltzer and Jean-Michel Claverie and Max Hantke and Olof Jönsson and Carl Nettelblad and Gijs van der Schot and Mengning Liang and Daniel P. DePonte and …

  12. Three-dimensional single-particle imaging using angular correlations from X-ray laser data

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    07 May 2013 | BioXFEL Publications | Contributor(s): Haiguang Liu, Billy K. Poon, Dilano Saldin, John Spence, Peter H. Zwart

    http://dx.doi.org/10.1107/s0108767313006016 journal-article Liu, H. et al., 2013. Three-dimensional single-particle imaging using angular correlations from X-ray laser data. Acta Crystallographica Section A Foundations of Crystallography, 69(4), pp.365–373. Available at: …

  13. Three-dimensional-printed gas dynamic virtual nozzles for x-ray laser sample delivery

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    18 May 2016 | BioXFEL Publications | Contributor(s): Garrett Charles Nelson, Richard Kirian, Uwe Weierstall, Nadia Zatsepin, Tomáš Faragó, Tilo Baumbach, Fabian Wilde, Fabian B. P. Niesler, Benjamin Zimmer, Izumi Ishigami, Masahide Hikita, Saša Bajt, Syun-Ru Yeh, Denis L. Rousseau, Henry Chapman, John Spence, Michael Heymann

    http://dx.doi.org/10.1364/oe.24.011515 Garrett Nelson and Richard A. Kirian and Uwe Weierstall and Nadia A. Zatsepin and Tomáš Faragó and Tilo Baumbach and Fabian Wilde and Fabian B. P. Niesler and Benjamin Zimmer and Izumi Ishigami and Masahide Hikita and Saša Bajt and Syun-Ru Yeh and Denis L. …

  14. Time-Resolved Contrast Variation SAXS for Studying RNA-Protein Interactions

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    15 Feb 2019 | BioXFEL Publications | Contributor(s): Suzette A. Pabit, Andrea Katz, George Douglas Calvey, Lois Pollack

    http://dx.doi.org/10.1016/j.bpj.2018.11.1733 poster Pabit, S.A. et al., 2019. Time-Resolved Contrast Variation SAXS for Studying RNA-Protein Interactions. Biophysical Journal, 116(3), p.319a–320a. Available at: http://dx.doi.org/10.1016/j.bpj.2018.11.1733. Suzette A. Pabit and Andrea M. Katz …

  15. Time-resolved cryogenic electron tomography for the study of transient cellular processes

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    08 May 2024 | BioXFEL Publications | Contributor(s): Joseph Yoniles, Jacob A. Summers, Kara Zielinski, Cali Antolini, Mayura Panjalingam, Stella Lisova, Frank R. Moss, Maximus Aldo Di Perna, Christopher Kupitz, Mark S. Hunter, Lois Pollack, Soichi Wakatsuki, Peter D. Dahlberg

    http://dx.doi.org/10.1091/mbc.e24-01-0042 Cryogenic electron tomography (cryo-ET) is the highest resolution imaging technique applicable to the life sciences, enabling subnanometer visualization of specimens preserved in their near native states. The rapid plunge freezing process used to prepare …

  16. Time-resolved cryogenic electron tomography for the study of transient cellular processes

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    08 May 2024 | BioXFEL Publications | Contributor(s): Joseph Yoniles, Jacob A. Summers, Kara Zielinski, Cali Antolini, Mayura Panjalingam, Stella Lisova, Frank R. Moss, Maximus Aldo Di Perna, Christopher Kupitz, Mark S. Hunter, Lois Pollack, Soichi Wakatsuki, Peter D. Dahlberg

    https://doi.org/10.1091/mbc.e24-01-0042 Cryogenic electron tomography (cryo-ET) is the highest resolution imaging technique applicable to the life sciences, enabling subnanometer visualization of specimens preserved in their near native states. The rapid plunge freezing process used to prepare …

  17. Time-Resolved Crystallography at X-ray Free Electron Lasers and Synchrotron Light Sources

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    09 Dec 2015 | BioXFEL Publications | Contributor(s): Marius Schmidt

    http://dx.doi.org/10.1080/08940886.2015.1101324 Marius Schmidt Schmidt, M., 2015. Time-Resolved Crystallography at X-ray Free Electron Lasers and Synchrotron Light Sources. Synchrotron Radiation News, 28(6), pp.25–30. Available at: http://dx.doi.org/10.1080/08940886.2015.1101324. NSF-STC Biology …

  18. Time-resolved Crystallography on Protein Photoreceptors and Enzymes

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    08 Dec 2023 | BioXFEL Publications | Contributor(s): Marius Schmidt

    http://dx.doi.org/10.1039/bk9781837670154-00203 Time-resolved macromolecular crystallography (TRX) unifies structure determination of biomolecules with chemical kinetics. Developed at synchrotron light sources, TRX has been transformed by serial femtosecond crystallography (SFX) at X-ray free …

  19. Time-resolved functional expansion of visual rhodopsin detected by x-ray scattering

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    11 Feb 2022 | BioXFEL Publications | Contributor(s): C. Swathi K. Menon, Konstantinos Karpos, Thomas D. Grant, Andrey V. Struts, Steven D.E. Fried, Roberto C. Alvarez, Suchithranga M.D.C. Perera, Irina V. Kosheleva, Alan Grossfield, Petra Fromme, Richard Kirian, Michael F. Brown

    http://dx.doi.org/10.1016/j.bpj.2021.11.1313 journal-article Menon, C. S. K., Karpos, K., Grant, T. D., Struts, A. V., Fried, S. D. E., Alvarez, R. C., Perera, S. M. D. C., Kosheleva, I. V., Grossfield, A., Fromme, P., Kirian, R. A., & Brown, M. F. (2022). Time-resolved functional expansion of …

  20. Time-Resolved Macromolecular Crystallography at Modern X-Ray Sources

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    01 Jun 2017 | BioXFEL Publications | Contributor(s): Marius Schmidt

    http://dx.doi.org/10.1007/978-1-4939-7000-1_11 book-chapter NSF-STC Biology with X-ray Lasers (NSF-1231306) Schmidt, M., 2017. Time-Resolved Macromolecular Crystallography at Modern X-Ray Sources. Protein Crystallography, pp.273–294. Available at: http://dx.doi.org/10.1007/978-1-4939-7000-1_11. …

  21. Time-resolved mixing-jet X-ray free-electron laser crystallography experiments

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    19 Dec 2017 | BioXFEL Publications | Contributor(s): Dominik Oberthuer, Juraj Knoška, Max Oliver Wiedorn, Saša Bajt, Henry Chapman

    http://dx.doi.org/10.1107/s2053273317087393 journal-article Oberthuer, D. et al., 2017. Time-resolved mixing-jet X-ray free-electron laser crystallography experiments. Acta Crystallographica Section A Foundations and Advances, 73(a2), pp.C835–C835. Available at: …

  22. Time-resolved serial crystallography captures high-resolution intermediates of photoactive yellow protein

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    04 Dec 2014 | BioXFEL Publications | Contributor(s): Jason Tenboer, Shibom Basu, Nadia Zatsepin, Kanupriya Pande, Despina Milathianaki, Matthias Frank, Mark S. Hunter, Sébastien Boutet, Garth J. Williams, Jason E. Koglin, Dominik Oberthuer, Michael Heymann, Christopher Kupitz, Chelsie E Conrad, Jesse David Coe, Shatabdi Roy-Chowdhury, Uwe Weierstall, Daniel James, Dingjie Wang, Thomas Grant, Anton Barty, Oleksandr Yefanov, Jennifer Scales, Cornelius Gati, Carolin Seuring, Vukica Srajer, Robert Henning, Peter Schwander, Raimund Fromme, Abbas Ourmazd, Keith Moffat, Jasper J. Van Thor, John Spence, Petra Fromme, Henry Chapman, Marius Schmidt

    http://dx.doi.org/10.1126/science.1259357 Jason Tenboer and Shibom Basu and Nadia Zatsepin and Kanupriya Pande and Despina Milathianaki and Matthias Frank and Mark Hunter and Sébastien Boutet and Garth J. Williams and Jason E. Koglin and Dominik Oberthuer and Michael Heymann and Christopher …

  23. Time-resolved serial crystallography captures high-resolution intermediates of photoactive yellow protein.

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    05 Dec 2014 | Publications

    Authors: Tenboer, J., Basu, S., Zatsepin, N., Pande, K., Milathianaki, D., Frank, M., Hunter, M., Boutet, S., Williams, G. J., Koglin, J. E., Oberthuer, D., Heymann, M., Kupitz, C., Conrad, C., Coe, J., Roy-Chowdhury, S., Weierstall, U., James, D., Wang, D., Grant, T., Barty, A., Yefanov, O., …

  24. Time-resolved serial femtosecond crystallography at the European XFEL

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    18 Nov 2019 | BioXFEL Publications | Contributor(s): Suraj Pandey, Richard Bean, Tokushi Sato, Ishwor Poudyal, Johan Bielecki, Jorvani Cruz Villarreal, Oleksandr Yefanov, Valerio Mariani, Thomas A. White, Christopher Kupitz, Mark S. Hunter, Mohamed H. Abdellatif, Saša Bajt, Valerii Bondar, Austin Echelmeier, Diandra Doppler, Moritz Emons, Matthias Frank, Raimund Fromme, Yaroslav Gevorkov, Gabriele Giovanetti, Man Jiang, Daihyun Kim, Yoonhee Kim, Henry Kirkwood, Anna Klimovskaia, Juraj Knoska, Faisal Hammad Mekky Koua, Romain Letrun, Stella Lisova, Luis Maia, Victoria Mazalova, Domingo Meza, Thomas Michelat, Abbas Ourmazd, Guido Palmer, Marco Ramilli, Robin Schubert, Peter Schwander, Alessandro Silenzi, Jolanta Sztuk-Dambietz, Alexandra Tolstikova, Henry Chapman, Alexandra Ros, Anton Barty, Petra Fromme, Adrian P. Mancuso, Marius Schmidt

    http://dx.doi.org/10.1038/s41592-019-0628-z journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Pandey, S. et al., 2019. Time-resolved serial femtosecond crystallography at the European XFEL. Nature Methods. Available at: http://dx.doi.org/10.1038/s41592-019-0628-z. Suraj Pandey and …

  25. Time-Resolved Spectra from Millivolt EELS Data

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    30 May 2014 | BioXFEL Publications | Contributor(s): Chufeng Li, GANESH SUBRAMANIAN, John Spence

    http://dx.doi.org/10.1017/s1431927614000890 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Li, C., Subramanian, G. & Spence, J.C.H., 2014. Time-Resolved Spectra from Millivolt EELS Data. Microscopy and Microanalysis, 20(03), pp.837–846. Available at: …

  26. Time-resolved structural studies with serial crystallography: A new light on retinal proteins

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    29 Jun 2015 | BioXFEL Publications | Contributor(s): Valérie Panneels, Wenting Wu, Ching-Ju Tsai, Przemek Nogly, Jan Rheinberger, Kathrin Jaeger, Gregor Cicchetti, Cornelius Gati, Leonhard M. Kick, Leonardo Sala, Guido Capitani, Chris Milne, Celestino Padeste, Bill Pedrini, Xiao-Dan Li, Jörg Standfuss, Rafael Abela, Gebhard F.X. Schertler

    journal-article http://dx.doi.org/10.1063/1.4922774 NSF-STC Biology with X-ray Lasers (NSF-1231306) Panneels, V. et al., 2015. Time-resolved structural studies with serial crystallography: A new light on retinal proteins. Structural Dynamics, 2(4), p.041718. Available at: …

  27. Toward Analysis of Proteins in Single Cells: A Quantitative Approach Employing Isobaric Tags with MALDI Mass Spectrometry Realized with a Microfluidic Platform

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    03 Jun 2016 | BioXFEL Publications | Contributor(s): Mian Yang, Randall Nelson, Alexandra Ros

    http://dx.doi.org/10.1021/acs.analchem.5b03419 journal-article Yang, M., Nelson, R. & Ros, A., 2016. Toward Analysis of Proteins in Single Cells: A Quantitative Approach Employing Isobaric Tags with MALDI Mass Spectrometry Realized with a Microfluidic Platform. Analytical Chemistry, 88(13), …

  28. Toward atomic resolution diffractive imaging of isolated molecules with X-ray free-electron lasers

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    15 Aug 2014 | BioXFEL Publications | Contributor(s): S. Stern, L. Holmegaard, F. Filsinger, A. Rouzée, A. Rudenko, P. Johnsson, A. V. Martin, A. Barty, C. Bostedt, J. Bozek, R. Coffee, S. Epp, B. Erk, L. Foucar, R. Hartmann, N. Kimmel, K-U. Kühnel, J. Maurer, M. Messerschmidt, B. Rudek, D. Starodub, J. Thøgersen, G. Weidenspointner, T. A. White, H. Stapelfeldt, D. Rolles, H. N. Chapman, J. Küpper

    http://dx.doi.org/10.1039/c4fd00028e S. Stern and L. Holmegaard and F. Filsinger and A. Rouzée and A. Rudenko and P. Johnsson and A. V. Martin and A. Barty and C. Bostedt and J. Bozek and R. Coffee and S. Epp and B. Erk and L. Foucar and R. Hartmann and N. Kimmel and K-U. Kühnel and J. Maurer and …

  29. Toward G protein-coupled receptor structure-based drug design using X-ray lasers

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    24 Oct 2019 | BioXFEL Publications | Contributor(s): Andrii Ishchenko, Benjamin Stauch, Gye Won Han, Alexander Batyuk, Anna Shiriaeva, Chufeng Li, Nadia Zatsepin, Uwe Weierstall, Wei Liu, Eriko Nango, Takanori Nakane, Rie Tanaka, Kensuke Tono, Yasumasa Joti, So Iwata, Isabel Moraes, Cornelius Gati, Vadim Cherezov

    http://dx.doi.org/10.1107/s2052252519013137 Rational structure-based drug design (SBDD) relies on the availability of a large number of co-crystal structures to map the ligand-binding pocket of the target protein and use this information for lead-compound optimization via an iterative process. …

  30. Toward steering a jet of particles into an x-ray beam with optically induced forces

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    25 Aug 2015 | BioXFEL Publications | Contributor(s): Niko Eckerskorn, Richard Bowman, Richard Kirian, Salah Awel, Max Oliver Wiedorn, Jochen Küpper, Miles J. Padgett, Henry Chapman, Andrei V. Rode

    http://dx.doi.org/10.1117/12.2191442 Niko Eckerskorn and Richard Bowman and Richard A. Kirian and Salah Awel and Max Wiedorn and Jochen Küpper and Miles J. Padgett and Henry N. Chapman and Andrei V. Rode Eckerskorn, N. et al., 2015. Toward steering a jet of particles into an x-ray beam with …

  31. Toward unsupervised single-shot diffractive imaging of heterogeneous particles using X-ray free-electron lasers

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    14 Nov 2013 | BioXFEL Publications | Contributor(s): Hyung Joo Park, N. Duane Loh, Raymond G. Sierra, Christina Y. Hampton, Dmitri Starodub, Andrew V. Martin, Anton Barty, Andrew Aquila, Joachim Schulz, Jan Steinbrener, Robert L. Shoeman, Lukas Lomb, Stephan Kassemeyer, Christoph Bostedt, John Bozek, Sascha W. Epp, Benjamin Erk, Robert Hartmann, Daniel Rolles, Artem Rudenko, Benedikt Rudek, Lutz Foucar, Nils Kimmel, Georg Weidenspointner, Guenter Hauser, Peter Holl, Emanuele Pedersoli, Mengning Liang, Mark S. Hunter, Lars Gumprecht, Nicola Coppola, Cornelia Wunderer, Heinz Graafsma, Filipe R.N.C. Maia, Tomas Ekeberg, Max Hantke, Holger Fleckenstein, Helmut Hirsemann, Karol Nass, Herbert J. Tobias, George R. Farquar, W. Henry Benner, Stefan Hau-Riege, Christian Reich, Andreas Hartmann, Heike Soltau, Stefano Marchesini, Sasa Bajt, Miriam Barthelmess, Lothar Strueder, Joachim Ullrich, Philip Bucksbaum, Matthias Frank, Ilme Schlichting, Henry Chapman, Michael J. Bogan, Veit Elser

    journal-article http://dx.doi.org/10.1364/oe.21.028729 Park, H.J. et al., 2013. Toward unsupervised single-shot diffractive imaging of heterogeneous particles using X-ray free-electron lasers. Optics Express, 21(23), p.28729. Available at: http://dx.doi.org/10.1364/oe.21.028729. Hyung Joo Park …

  32. Towards a generalised approach for the time-resolved crystallographic study of enzymes

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    05 Jan 2016 | BioXFEL Publications | Contributor(s): Diana C. F. Monteiro, Vijay Patel, Christopher P. Bartlett, Shingo Nozaki, Thomas D. Grant, James A. Gowdy, Gary S. Thompson, Arnout P. Kalverda, Edward Snell, Hironori Niki, Arwen R. Pearson, Michael E. Webb

    http://dx.doi.org/10.1107/s205327331509957x Diana C. F. Monteiro and Vijay Patel and Christopher P. Bartlett and Shingo Nozaki and Thomas D. Grant and James A. Gowdy and Gary S. Thompson and Arnout P. Kalverda and Edward H. Snell and Hironori Niki and Arwen R. Pearson and Michael E. Webb Monteiro, …

  33. Towards phasing using high X-ray intensity

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    29 Sep 2015 | BioXFEL Publications | Contributor(s): Lorenzo Galli, Sang-Kil Son, Thomas R. M. Barends, Thomas A. White, Anton Barty, Sabine Botha, Sébastien Boutet, Carl Caleman, R. Bruce Doak, Max H. Nanao, Karol Nass, Robert L. Shoeman, Nicusor Timneanu, Robin Santra, Ilme Schlichting, Henry Chapman

    X-ray free-electron lasers (XFELs) show great promise for macromolecular structure determination from sub-micrometre-sized crystals, using the emerging method of serial femtosecond crystallography. The extreme brightness of the XFEL radiation can multiply ionize most, if not all, atoms in a …

  34. Towards protein-crystal centering using second-harmonic generation (SHG) microscopy

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    18 Apr 2013 | BioXFEL Publications | Contributor(s): David J. Kissick, Christopher M. Dettmar, Michael Becker, Anne M. Mulichak, Vadim Cherezov, Stephan L. Ginell, Kevin P. Battaile, Lisa J. Keefe, Robert F. Fischetti, Garth J. Simpson

    http://dx.doi.org/10.1107/s0907444913002746 journal-article Kissick, D.J. et al., 2013. Towards protein-crystal centering using second-harmonic generation (SHG) microscopy. Acta Crystallographica Section D Biological Crystallography, 69(5), pp.843–851. Available at: …

  35. Towards RIP using free-electron laser SFX data

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    04 Feb 2015 | BioXFEL Publications | Contributor(s): Lorenzo Galli, Sang-Kil Son, Thomas A. White, Robin Santra, Henry Chapman, Max H. Nanao

    Here, it is shown that simulated native serial femtosecond crystallography (SFX) cathepsin B data can be phased by rapid ionization of sulfur atoms. Utilizing standard software adopted for radiation-damage-induced phasing (RIP), the effects on both substructure determination and phasing of the …

  36. Towards time-resolved serial crystallography in a microfluidic device

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    26 Jun 2015 | BioXFEL Publications | Contributor(s): Ashtamurthy S. Pawate, Vukica Šrajer, Jeremy Schieferstein, Sudipto Guha, Robert Henning, Irina Kosheleva, Marius Schmidt, Zhong Ren, Paul J. A. Kenis, Sarah Perry

    Serial methods for crystallography have the potential to enable dynamic structural studies of protein targets that have been resistant to single-crystal strategies. The use of serial data-collection strategies can circumvent challenges associated with radiation damage and repeated reaction …

  37. Toxicity of Eosinophil MBP Is Repressed by Intracellular Crystallization and Promoted by Extracellular Aggregation

    0.0 out of 5 stars 

    26 Feb 2015 | BioXFEL Publications | Contributor(s): Alice Soragni, Shida Yousefi, Christina Stoeckle, Angela B. Soriaga, Michael R. Sawaya, Evelyne Kozlowski, Inès Schmid, Susanne Radonjic-Hoesli, Sebastien Boutet, Garth J. Williams, Marc Messerschmidt, M. Marvin Seibert, Duilio Cascio, Nadia A. Zatsepin, Manfred Burghammer, Christian Riekel, Jacques-Philippe Colletier, Roland Riek, David S. Eisenberg, Hans-Uwe Simon

    http://dx.doi.org/10.1016/j.molcel.2015.01.026 Alice Soragni and Shida Yousefi and Christina Stoeckle and Angela B. Soriaga and Michael R. Sawaya and Evelyne Kozlowski and Inès Schmid and Susanne Radonjic-Hoesli and Sebastien Boutet and Garth J. Williams and Marc Messerschmidt and M. Marvin …

  38. Trace phase detection and strain characterization from serial X-ray free-electron laser crystallography of a Pr0.5Ca0.5MnO3 powder

    0.0 out of 5 stars 

    17 Nov 2014 | BioXFEL Publications | Contributor(s): Kenneth R. Beyerlein, Christian Jooss, Anton Barty, Richard Bean, Sébastien Boutet, Sarnjeet S. Dhesi, R. Bruce Doak, Michael Först, Lorenzo Galli, Richard Kirian, Joseph Kozak, Michael Lang, Roman Mankowsky, Marc Messerschmidt, John Spence, Dingjie Wang, Uwe Weierstall, Thomas A. White, Garth J. Williams, Oleksandr Yefanov, Nadia Zatsepin, Andrea Cavalleri, Henry Chapman

    http://dx.doi.org/10.1017/s0885715614001171 We report on the analysis of virtual powder-diffraction patterns from serial femtosecond crystallography (SFX) data collected at an X-ray free-electron laser. Different approaches to binning and normalizing these patterns are discussed with respect to the …

  39. Trajectories of the ribosome as a Brownian nanomachine

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    24 Nov 2014 | BioXFEL Publications | Contributor(s): Ali Dashti, Peter Schwander, Robert Langlois, Russell Fung, Wen Li, Ahmad Hosseinizadeh, Hstau Y. Liao, Jesper Pallesen, Gyanesh Sharma, Vera A. Stupina, Anne E. Simon, Jonathan D. Dinman, Joachim Frank, Abbas Ourmazd

    http://dx.doi.org/10.1073/pnas.1419276111 Ali Dashti and Peter Schwander and Robert Langlois and Russell Fung and Wen Li and Ahmad Hosseinizadeh and Hstau Y. Liao and Jesper Pallesen and Gyanesh Sharma and Vera A. Stupina and Anne E. Simon and Jonathan D. Dinman and Joachim Frank and Abbas Ourmazd …

  40. Trajectories of the ribosome as a Brownian nanomachine

    0.0 out of 5 stars 

    12 Apr 2018 | BioXFEL Publications | Contributor(s): Ali Dashti, Peter Schwander, Robert Langlois, Russell Fung, Wen Li, Ahmad Hosseinizadeh, Hstau Y. Liao, Jesper Pallesen, Gyanesh Sharma, Vera A. Stupina, Anne E. Simon, Jonathan D. Dinman, Joachim Frank, Abbas Ourmazd

    http://dx.doi.org/10.1142/9789813234864_0048 book-chapter Dashti, A. et al., 2018. Trajectories of the ribosome as a Brownian nanomachine. Single-Particle Cryo-Electron Microscopy, pp.463–475. Available at: http://dx.doi.org/10.1142/9789813234864_0048. Ali Dashti and Peter Schwander and Robert …

  41. Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms

    0.0 out of 5 stars 

    14 Apr 2014 | BioXFEL Publications | Contributor(s): V. Schweikhard, C. Meng, K. Murakami, C. D. Kaplan, R. D. Kornberg, S. M. Block

    journal-article http://dx.doi.org/10.1073/pnas.1405181111 Schweikhard, V. et al., 2014. Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms. Proceedings of the National Academy of Sciences, 111(18), pp.6642–6647. …

  42. Transferring the entatic-state principle to copper photochemistry

    0.0 out of 5 stars 

    15 Jan 2018 | BioXFEL Publications | Contributor(s): B. Dicke, A. Hoffmann, J. Stanek, M. S. Rampp, B. Grimm-Lebsanft, F. Biebl, D. Rukser, B. Maerz, D. Göries, M. Naumova, M. Biednov, G. Neuber, A. Wetzel, S. M. Hofmann, P. Roedig, A. Meents, J. Bielecki, J. Andreasson, K. R. Beyerlein, H. N. Chapman, C. Bressler, W. Zinth, M. Rübhausen, S. Herres-Pawlis

    http://dx.doi.org/10.1038/nchem.2916 journal-article Dicke, B. et al., 2018. Transferring the entatic-state principle to copper photochemistry. Nature Chemistry. Available at: http://dx.doi.org/10.1038/nchem.2916. B. Dicke and A. Hoffmann and J. Stanek and M. S. Rampp and B. Grimm-Lebsanft and …

  43. Transient lattice contraction in the solid-to-plasma transition

    0.0 out of 5 stars 

    29 Jan 2016 | BioXFEL Publications | Contributor(s): Ken R. Ferguson, Maximilian Bucher, Tais Gorkhover, Sébastien Boutet, Hironobu Fukuzawa, Jason E. Koglin, Yoshiaki Kumagai, Alberto Lutman, Agostino Marinelli, Marc Messerschmidt, Kiyonobu Nagaya, Jim Turner, Kiyoshi Ueda, Garth J. Williams, Philip H. Bucksbaum, Christoph Bostedt

    http://dx.doi.org/10.1126/sciadv.1500837 Ken R. Ferguson and Maximilian Bucher and Tais Gorkhover and Sébastien Boutet and Hironobu Fukuzawa and Jason E. Koglin and Yoshiaki Kumagai and Alberto Lutman and Agostino Marinelli and Marc Messerschmidt and Kiyonobu Nagaya and Jim Turner and Kiyoshi Ueda …

  44. Transient state measurements on proteins by time-resolved crystallography

    0.0 out of 5 stars 

    22 Apr 2022 | BioXFEL Publications | Contributor(s): Tek Narsingh Malla, Marius Schmidt

    http://dx.doi.org/10.1016/j.sbi.2022.102376 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Malla, T. N., & Schmidt, M. (2022). Transient state measurements on proteins by time-resolved crystallography. Current Opinion in Structural Biology, 74, 102376. …

  45. Transmission electron microscopy for the evaluation and optimization of crystal growth

    0.0 out of 5 stars 

    26 Apr 2016 | BioXFEL Publications | Contributor(s): Hilary P. Stevenson, Guowu Lin, Christopher Barnes, Ieva Sutkeviciute, Troy Krzysiak, Simon C. Weiss, Shelley Reynolds, Ying Wu, Veeranagu Nagarajan, Alexander M. Makhov, Robert M Lawrence, Emily Lamm, Lisa Clark, Timothy J. Gardella, Brenda Hogue, Craig M. Ogata, Jinwoo Ahn, Angela M. Gronenborn, James F. Conway, Jean-Pierre Vilardaga, Aina E. Cohen, Guillermo Calero

    The crystallization of protein samples remains the most significant challenge in structure determination by X-ray crystallography. Here, the effectiveness of transmission electron microscopy (TEM) analysis to aid in the crystallization of biological macromolecules is demonstrated. It was found that …

  46. Tuning RNA Flexibility with Helix Length and Junction Sequence

    0.0 out of 5 stars 

    15 Dec 2015 | BioXFEL Publications | Contributor(s): Julie L. Sutton, Lois Pollack

    http://dx.doi.org/10.1016/j.bpj.2015.10.039 journal-article Sutton, J.L. & Pollack, L., 2015. Tuning RNA Flexibility with Helix Length and Junction Sequence. Biophysical Journal, 109(12), pp.2644–2653. Available at: http://dx.doi.org/10.1016/j.bpj.2015.10.039. Julie L. Sutton and Lois Pollack

  47. Turning up the heat on molecular machines with multi-temperature and temperature-jump X-ray scattering experiments

    0.0 out of 5 stars 

    21 Oct 2021 | BioXFEL Publications | Contributor(s): Michael Thompson, Alexander Wolff, Benjamin Barad, Wilson Nieves Vasquez, Nathaniel Brown, Hyun Sun Cho, Friedrich Schotte, Valentyn Stadnytskyi, Philip Anfinrud, James Fraser

    http://dx.doi.org/10.1107/s0108767321097841 journal-article Thompson, M., Wolff, A., Barad, B., Vasquez, W. N., Brown, N., Cho, H. S., Schotte, F., Stadnytskyi, V., Anfinrud, P., & Fraser, J. (2021). Turning up the heat on molecular machines with multi-temperature and temperature-jump X-ray …

  48. Two disparate ligand-binding sites in the human P2Y1 receptor

    0.0 out of 5 stars 

    30 Mar 2015 | BioXFEL Publications | Contributor(s): Dandan Zhang, Zhan-Guo Gao, Kaihua Zhang, Evgeny Kiselev, Steven Crane, Jiang Wang, Silvia Paoletta, Cuiying Yi, Limin Ma, Wenru Zhang, Gye Won Han, Hong Liu, Vadim Cherezov, Vsevolod Katritch, Hualiang Jiang, Raymond C. Stevens, Kenneth A. Jacobson, Qiang Zhao, Beili Wu

    http://dx.doi.org/10.1038/nature14287 Dandan Zhang and Zhan-Guo Gao and Kaihua Zhang and Evgeny Kiselev and Steven Crane and Jiang Wang and Silvia Paoletta and Cuiying Yi and Limin Ma and Wenru Zhang and Gye Won Han and Hong Liu and Vadim Cherezov and Vsevolod Katritch and Hualiang Jiang and …

  49. Ultrafast Membrane Protein Dynamics Revealed by X-Ray Scattering with a Femtosecond Free-Electron Laser

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    12 Feb 2021 | BioXFEL Publications | Contributor(s): Thomas D. Grant, Suchithranga M.D.C. Perera, Leslie A. Salas-Estrada, Andrey V. Struts, Udeep Chawla, Steven D.E. Fried, Nipuna Weerasinghe, Kostantinos Karpos, Domingo Meza, Nadia Zatsepin, Alan Grossfield, Derek Mendez, Petra Fromme, Richard Kirian, Michael F. Brown

    http://dx.doi.org/10.1016/j.bpj.2020.11.1006 journal-article Grant, T.D. et al., 2021. Ultrafast Membrane Protein Dynamics Revealed by X-Ray Scattering with a Femtosecond Free-Electron Laser. Biophysical Journal, 120(3), p.133a. Available at: http://dx.doi.org/10.1016/j.bpj.2020.11.1006. Thomas …

  50. Ultrafast nonthermal heating of water initiated by an X-ray Free-Electron Laser

    0.0 out of 5 stars 

    14 May 2018 | BioXFEL Publications | Contributor(s): Kenneth R. Beyerlein, H. Olof Jönsson, Roberto Alonso-Mori, Andrew Aquila, Saša Bajt, Anton Barty, Richard Bean, Jason E. Koglin, Marc Messerschmidt, Davide Ragazzon, Dimosthenis Sokaras, Garth J. Williams, Stefan Hau-Riege, Sébastien Boutet, Henry Chapman, Nicuşor Tîmneanu, Carl Caleman

    http://dx.doi.org/10.1073/pnas.1711220115 journal-article Beyerlein, K.R. et al., 2018. Ultrafast nonthermal heating of water initiated by an X-ray Free-Electron Laser. Proceedings of the National Academy of Sciences, p.201711220. Available at: http://dx.doi.org/10.1073/pnas.1711220115. Kenneth …

  51. Ultrafast self-gating Bragg diffraction of exploding nanocrystals in an X-ray laser

    0.0 out of 5 stars 

    20 Jan 2015 | BioXFEL Publications | Contributor(s): Carl Caleman, Nicuşor Tîmneanu, Andrew V. Martin, H. Olof Jönsson, Andrew Aquila, Anton Barty, Howard A. Scott, Thomas A. White, Henry Chapman

    http://dx.doi.org/10.1364/oe.23.001213 Carl Caleman and Nicuşor Tîmneanu and Andrew V. Martin and H. Olof Jönsson and Andrew Aquila and Anton Barty and Howard A. Scott and Thomas A. White and Henry N. Chapman Caleman, C. et al., 2015. Ultrafast self-gating Bragg diffraction of exploding …

  52. Ultrafast Three-Dimensional Imaging of Lattice Dynamics in Individual Gold Nanocrystals

    0.0 out of 5 stars 

    24 May 2013 | BioXFEL Publications | Contributor(s): J. N. Clark, L. Beitra, G. Xiong, A. Higginbotham, D. M. Fritz, H. T. Lemke, D. Zhu, M. Chollet, G. J. Williams, M. Messerschmidt, B. Abbey, R. J. Harder, A. M. Korsunsky, J. S. Wark, I. K. Robinson

    http://dx.doi.org/10.1126/science.1236034 journal-article Clark, J.N. et al., 2013. Ultrafast Three-Dimensional Imaging of Lattice Dynamics in Individual Gold Nanocrystals. Science, 341(6141), pp.56–59. Available at: http://dx.doi.org/10.1126/science.1236034. J. N. Clark and L. Beitra and G. …

  53. Ultrafast X-ray probing of water structure below the homogeneous ice nucleation temperature

    0.0 out of 5 stars 

    17 Jun 2014 | BioXFEL Publications | Contributor(s): J. A. Sellberg, C. Huang, T. A. McQueen, N. D. Loh, H. Laksmono, D. Schlesinger, R. G. Sierra, D. Nordlund, C. Y. Hampton, D. Starodub, D. P. DePonte, M. Beye, C. Chen, A. V. Martin, A. Barty, K. T. Wikfeldt, T. M. Weiss, C. Caronna, J. Feldkamp, L. B. Skinner, M. M. Seibert, M. Messerschmidt, G. J. Williams, S. Boutet, L. G. M. Pettersson, M. J. Bogan, A. Nilsson

    journal-article http://dx.doi.org/10.1038/nature13266 Sellberg, J.A. et al., 2014. Ultrafast X-ray probing of water structure below the homogeneous ice nucleation temperature. Nature, 510(7505), pp.381–384. Available at: http://dx.doi.org/10.1038/nature13266. J. A. Sellberg and C. Huang and T. …

  54. Uncoupling Promoter Opening from Start-Site Scanning

    0.0 out of 5 stars 

    13 Jun 2015 | BioXFEL Publications | Contributor(s): Kenji Murakami, Pierre-Jean Mattei, Ralph E. Davis, Huiyan Jin, Craig D. Kaplan, Roger D. Kornberg

    journal-article http://dx.doi.org/10.1016/j.molcel.2015.05.021 Murakami, K. et al., 2015. Uncoupling Promoter Opening from Start-Site Scanning. Molecular Cell, 59(1), pp.133–138. Available at: http://dx.doi.org/10.1016/j.molcel.2015.05.021. Kenji Murakami and Pierre-Jean Mattei and Ralph E. …

  55. Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT fromSulfolobus solfataricus

    0.0 out of 5 stars 

    20 Mar 2014 | BioXFEL Publications | Contributor(s): Fengbin Wang, Shanteri Singh, Jianjun Zhang, Tyler D. Huber, Kate E. Helmich, Manjula Sunkara, Katherine A. Hurley, Randal D. Goff, Craig A. Bingman, Andrew J. Morris, Jon S. Thorson, George Phillips

    http://dx.doi.org/10.1111/febs.12784 journal-article Wang, F. et al., 2014. Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT fromSulfolobus solfataricus. FEBS Journal, 281(18), pp.4224–4239. Available at: …

  56. Understanding nucleic acid structural changes by comparing wide-angle x-ray scattering (WAXS) experiments to molecular dynamics simulations

    0.0 out of 5 stars 

    25 May 2016 | BioXFEL Publications | Contributor(s): Suzette A. Pabit, Andrea Katz, Igor S. Tolokh, Aleksander Drozdetski, Nathan Baker, Alexey V. Onufriev, Lois Pollack

    http://dx.doi.org/10.1063/1.4950814 journal-article Pabit, S.A. et al., 2016. Understanding nucleic acid structural changes by comparing wide-angle x-ray scattering (WAXS) experiments to molecular dynamics simulations. The Journal of Chemical Physics, 144(20), p.205102. Available at: …

  57. Unique patterns of transcript and miRNA expression in the South American strong voltage electric eel (Electrophorus electricus)

    0.0 out of 5 stars 

    25 Mar 2015 | BioXFEL Publications | Contributor(s): Lindsay L Traeger, Jeremy D Volkening, Howell Moffett, Jason R Gallant, Po-Hao Chen, Carl D Novina, George Phillips, Rene Anand, Gregg B Wells, Matthew Pinch, Robert Güth, Graciela A Unguez, James S Albert, Harold Zakon, Michael R Sussman, Manoj P Samanta

    http://dx.doi.org/10.1186/s12864-015-1288-8 Lindsay L Traeger and Jeremy D Volkening and Howell Moffett and Jason R Gallant and Po-Hao Chen and Carl D Novina and George N Phillips and Rene Anand and Gregg B Wells and Matthew Pinch and Robert Güth and Graciela A Unguez and James S Albert and Harold …

  58. Use of transmission electron microscopy to identify nanocrystals of challenging protein targets

    0.0 out of 5 stars 

    28 May 2014 | BioXFEL Publications | Contributor(s): H. P. Stevenson, A. M. Makhov, M. Calero, A. L. Edwards, O. B. Zeldin, I. I. Mathews, G. Lin, C. O. Barnes, H. Santamaria, T. M. Ross, S. M. Soltis, C. Khosla, V. Nagarajan, J. F. Conway, A. E. Cohen, G. Calero

    http://dx.doi.org/10.1073/pnas.1400240111 journal-article Stevenson, H.P. et al., 2014. Use of transmission electron microscopy to identify nanocrystals of challenging protein targets. Proceedings of the National Academy of Sciences, 111(23), pp.8470–8475. Available at: …

  59. Use of triple correlations for the sign determinations of expansion coefficients of symmetric approximations to the diffraction volumes of regular viruses

    0.0 out of 5 stars 

    18 Jun 2015 | BioXFEL Publications | Contributor(s): H. C. Poon, D. K. Saldin

    http://dx.doi.org/10.1063/1.4922476 H. C. Poon and D. K. Saldin Poon, H.C. & Saldin, D.K., 2015. Use of triple correlations for the sign determinations of expansion coefficients of symmetric approximations to the diffraction volumes of regular viruses. Structural Dynamics, 2(4), p.041716. Available …

  60. Using a commodity high-definition television for collaborative structural biology

    0.0 out of 5 stars 

    28 May 2014 | BioXFEL Publications | Contributor(s): Ragothaman Yennamalli, Raj Arangarasan, Aaron Bryden, Michael Gleicher, George Phillips

    Visualization of protein structures using stereoscopic systems is frequently needed by structural biologists working to understand a protein's structure–function relationships. Often several scientists are working as a team and need simultaneous interaction with each other and the graphics …

  61. Using deep mutational scanning to identify the determinants of antibiotic resistance

    0.0 out of 5 stars 

    11 Feb 2022 | BioXFEL Publications | Contributor(s): Christian B. Macdonald, Alexis Kelley, Jenna Pellegrino, Willow Coyote-Maestas, James Fraser

    http://dx.doi.org/10.1016/j.bpj.2021.11.665 journal-article Macdonald, C. B., Kelley, A., Pellegrino, J., Coyote-Maestas, W., & Fraser, J. (2022). Using deep mutational scanning to identify the determinants of antibiotic resistance. Biophysical Journal, 121(3), 422a. …

  62. Using Machine Learning to Achieve Accurate Estimates of Fetal Gestational Age and Personalized Predictions of Fetal Growth

    0.0 out of 5 stars 

    24 Mar 2020 | BioXFEL Publications | Contributor(s): Russell Fung, Jose Villar, Ali Dashti, Leila Cheikh Ismail, Eleonora Staines-Urias, Eric O. Ohuma, Laurent J. Salomon, Cesar G. Victora, Fernando C. Barros, Ann Lambert, Maria Carvalho, Yasmin A. Jaffer, Alison J. Noble, Michael G. Gravett, Manorama Purwar, Ruyan Pang, Enrico Bertino, Shama Munim, Aung Myat Min, Rose McGready, Shane A. Norris, Zulfiqar A Bhutta, Stephen H. Kennedy, Aris T. Papageorghiou, Abbas Ourmazd, International Fetal And Newborn Gro Group

    http://dx.doi.org/10.2139/ssrn.3471997 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Fung, R. et al., 2019. Using Machine Learning to Achieve Accurate Estimates of Fetal Gestational Age and Personalized Predictions of Fetal Growth. SSRN Electronic Journal. Available at: …

  63. Using X-ray Diffraction Techniques for Biomimetic Drug Development, Formulation, and Polymorphic Characterization

    0.0 out of 5 stars 

    30 Dec 2020 | BioXFEL Publications | Contributor(s): Israel Rodriguez, Ritika Gautam, Arthur Tinoco

    http://dx.doi.org/10.3390/biomimetics6010001 Drug development is a decades-long, multibillion dollar investment that often limits itself. To decrease the time to drug approval, efforts are focused on drug targets and drug formulation for optimal biocompatibility and efficacy. X-ray structural …

  64. Using XFELs to measure the solution structures of biomolecules

    0.0 out of 5 stars 

    13 Oct 2015 | Teaching Materials

    Dr. Lois Pollack presents an introduction to small and wide angle X-ray solution scattering techniques and describes the advances made possible by XFELs.

  65. Valence electron energy-loss spectroscopy study of ZrSiO4 and ZrO2

    0.0 out of 5 stars 

    16 Jul 2013 | BioXFEL Publications | Contributor(s): Nan Jiang, John Spence

    journal-article http://dx.doi.org/10.1016/j.ultramic.2013.06.021 Jiang, N. & Spence, J.C.H., 2013. Valence electron energy-loss spectroscopy study of ZrSiO4 and ZrO2. Ultramicroscopy, 134, pp.68–76. Available at: http://dx.doi.org/10.1016/j.ultramic.2013.06.021. Nan Jiang and John C.H. Spence

  66. Vibrational Excitations and Low-Energy Electronic Structure of Epoxide-Decorated Graphene

    0.0 out of 5 stars 

    17 Dec 2013 | BioXFEL Publications | Contributor(s): E. C. Mattson, J. E. Johns, K. Pande, R. A. Bosch, S. Cui, M. Gajdardziska-Josifovska, M. Weinert, J. H. Chen, M. C. Hersam, C. J. Hirschmugl

    journal-article http://dx.doi.org/10.1021/jz4025386 Mattson, E.C. et al., 2014. Vibrational Excitations and Low-Energy Electronic Structure of Epoxide-Decorated Graphene. The Journal of Physical Chemistry Letters, 5(1), pp.212–219. Available at: http://dx.doi.org/10.1021/jz4025386. E. C. …

  67. Viral anti‐inflammatory serpin reduces immuno‐coagulopathic pathology in SARS‐CoV‐2 mouse models of infection

    0.0 out of 5 stars 

    03 Aug 2023 | BioXFEL Publications | Contributor(s): Liqiang Zhang, Yize (Henry) Li, Karen Kibler, Simona Kraberger, Arvind Varsani, Julie Turk, Nora Elmadbouly, Emily Aliskevich, Laurel Spaccarelli, Bereket Estifanos, Junior Enow, Isabela Rivabem Zanetti, Nicholas Saldevar, Efrem Lim, Jessika Schlievert, Kyle Browder, Anjali Wilson, Fernando Arcos Juan, Aubrey Pinteric, Aman Garg, Henna Monder, Rohan Saju, Savanah Gisriel, Bertram Jacobs, Timothy L Karr, Esther Borges Florsheim, Vivek Kumar, John Wallen, Masmudur Rahman, Grant McFadden, Brenda Hogue, Alexandra R Lucas

    http://dx.doi.org/10.15252/emmm.202317376 AbstractSARS‐CoV‐2 acute respiratory distress syndrome (ARDS) induces uncontrolled lung inflammation and coagulopathy with high mortality. Anti‐viral drugs and monoclonal antibodies reduce early COVID‐19 severity, but treatments for late‐stage …

  68. Viral RNA Folding Studied through Contrast Variation Small Angle- X Ray Scattering

    0.0 out of 5 stars 

    07 Feb 2020 | BioXFEL Publications | Contributor(s): Josue San Emeterio, Lois Pollack

    http://dx.doi.org/10.1016/j.bpj.2019.11.1319 journal-article Emeterio, J. S., & Pollack, L. (2020). Viral RNA Folding Studied through Contrast Variation Small Angle- X Ray Scattering. Biophysical Journal, 118(3), 222a. https://doi.org/10.1016/j.bpj.2019.11.1319 Josue San Emeterio and Lois Pollack

  69. Virtual discovery of melatonin receptor ligands to modulate circadian rhythms

    0.0 out of 5 stars 

    10 Feb 2020 | BioXFEL Publications | Contributor(s): Reed M. Stein, Hye Jin Kang, John D. McCorvy, Grant C. Glatfelter, Anthony J. Jones, Tao Che, Samuel Slocum, Xi-Ping Huang, Olena Savych, Yurii S. Moroz, Benjamin Stauch, Linda C. Johansson, Vadim Cherezov, Terry Kenakin, John J. Irwin, Brian K. Shoichet, Bryan L. Roth, Margarita L. Dubocovich

    http://dx.doi.org/10.1038/s41586-020-2027-0 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Stein, R.M. et al., 2020. Virtual discovery of melatonin receptor ligands to modulate circadian rhythms. Nature. Available at: http://dx.doi.org/10.1038/s41586-020-2027-0. Reed M. Stein and …

  70. Virus Crystallography

    0.0 out of 5 stars 

    14 Oct 2015 | Teaching Materials | Contributor(s): Robert M Lawrence

    Dr. Rob Lawrence describes the unique problems associated with crystallization of virus particles and different methods to overcome them.

  71. Virus Dynamics Studied by Time-Resolved Small Angle X-Ray Scattering

    0.0 out of 5 stars 

    15 Feb 2019 | BioXFEL Publications | Contributor(s): Josue San Emeterio, Lois Pollack

    http://dx.doi.org/10.1016/j.bpj.2018.11.2321 journal-article San Emeterio, J., & Pollack, L. (2019). Virus Dynamics Studied by Time-Resolved Small Angle X-Ray Scattering. Biophysical Journal, 116(3), 431a. https://doi.org/10.1016/j.bpj.2018.11.2321 Josue San Emeterio and Lois Pollack

  72. Visualization of biomolecular structures by WAXS and MD

    0.0 out of 5 stars 

    21 Oct 2021 | BioXFEL Publications | Contributor(s): Weiwei He, Yen-Lin Chen, Serdal Kirmizialtin, Lois Pollack

    http://dx.doi.org/10.1107/s0108767321098755 journal-article He, W., Chen, Y.-L., Kirmizialtin, S., & Pollack, L. (2021). Visualization of biomolecular structures by WAXS and MD. Acta Crystallographica Section A Foundations and Advances, 77(a1), a124–a124. …

  73. Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser

    0.0 out of 5 stars 

    13 Oct 2015 | Teaching Materials

    We describe a method to measure ultrafast protein structural changes using time-resolved wide-angle X-ray scattering at an X-ray free-electron laser. We demonstrated this approach using multiphoton excitation of the Blastochloris viridis photosynthetic reaction center, observing an ultrafast …

  74. Visualizing aerosol-particle injection for diffractive-imaging experiments

    0.0 out of 5 stars 

    16 Mar 2016 | BioXFEL Publications | Contributor(s): Salah Awel, Richard Kirian, Niko Eckerskorn, Max Oliver Wiedorn, Daniel A. Horke, Andrei V. Rode, Jochen Küpper, Henry Chapman

    http://dx.doi.org/10.1364/oe.24.006507 Salah Awel and Richard A. Kirian and Niko Eckerskorn and Max Wiedorn and Daniel A. Horke and Andrei V. Rode and Jochen Küpper and Henry N. Chapman Awel, S. et al., 2016. Visualizing aerosol-particle injection for diffractive-imaging experiments. Optics …

  75. Visualizing Disordered Single-Stranded RNA: Connecting Sequence, Structure, and Electrostatics

    0.0 out of 5 stars 

    05 Dec 2019 | BioXFEL Publications | Contributor(s): Alex Plumridge, Kurt Andresen, Lois Pollack

    http://dx.doi.org/10.1021/jacs.9b04461 journal-article Plumridge, A., Andresen, K. & Pollack, L., 2019. Visualizing Disordered Single-Stranded RNA: Connecting Sequence, Structure, and Electrostatics. Journal of the American Chemical Society. Available at: http://dx.doi.org/10.1021/jacs.9b04461. …

  76. Visualizing single-stranded nucleic acids in solution

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    13 Dec 2016 | BioXFEL Publications | Contributor(s): Alex Plumridge, Steve P. Meisburger, Lois Pollack

    http://dx.doi.org/10.1093/nar/gkw1297 journal-article Plumridge, A., Meisburger, S.P. & Pollack, L., 2016. Visualizing single-stranded nucleic acids in solution. Nucleic Acids Research, p.gkw1297. Available at: http://dx.doi.org/10.1093/nar/gkw1297. Alex Plumridge and Steve P. Meisburger and …

  77. Vitamin C Binds to SARS Coronavirus-2 Main Protease Essential for Viral Replication

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    04 May 2021 | BioXFEL Publications | Contributor(s): Tek Narsingh Malla, Suraj Pandey, Luis Aldama, Dennisse Feliz, Moraima Noda, Ishwor Poudyal, George Phillips, Emina Stojkovic, Marius Schmidt

    http://dx.doi.org/10.1101/2021.05.02.442358 AbstractThere is an urgent need for anti-viral agents that treat and/or prevent Covid-19 caused by SARS-Coronavirus (CoV-2) infections. The replication of the SARS CoV-2 is dependent on the activity of two cysteine proteases, a papain-like protease, …

  78. Volume-conserving trans–cis isomerization pathways in photoactive yellow protein visualized by picosecond X-ray crystallography

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    01 Feb 2013 | BioXFEL Publications | Contributor(s): Yang Ouk Jung, Jae Hyuk Lee, Joonghan Kim, Marius Schmidt, Keith Moffat, Vukica Šrajer, Hyotcherl Ihee

    http://dx.doi.org/10.1038/nchem.1565 journal-article Jung, Y.O. et al., 2013. Volume-conserving trans–cis isomerization pathways in photoactive yellow protein visualized by picosecond X-ray crystallography. Nature Chemistry, 5(3), pp.212–220. Available at: …

  79. Watching proteins function with time-resolved x-ray crystallography

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    03 Jul 2017 | BioXFEL Publications | Contributor(s): Vukica Šrajer, Marius Schmidt

    http://dx.doi.org/10.1088/1361-6463/aa7d32 journal-article Šrajer, V. & Schmidt, M., 2017. Watching proteins function with time-resolved x-ray crystallography. Journal of Physics D: Applied Physics, 50(37), p.373001. Available at: http://dx.doi.org/10.1088/1361-6463/aa7d32. Vukica Šrajer and …

  80. What is the outcome of your crystallization experiment

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    14 Oct 2015 | Teaching Materials | Contributor(s): Joseph Luft

    Joe Luft discusses the detection of hits in crystallization screening experiments for both macro and nanocrystals.

  81. What it takes for a successful mix-and-inject serial crystallography experiment: from a sample preparation and sample delivery perspective

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    21 Oct 2021 | BioXFEL Publications | Contributor(s): Kara Zielinski, Lois Pollack

    http://dx.doi.org/10.1107/s0108767321099219 journal-article Zielinski, K., & Pollack, L. (2021). What it takes for a successful mix-and-inject serial crystallography experiment: from a sample preparation and sample delivery perspective. Acta Crystallographica Section A Foundations and Advances, …

  82. When Your Crystals Bite

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    14 Oct 2015 | Teaching Materials | Contributor(s): George Phillips

    Dr. George Phillips describes properties of crystals such as twinning and other defects and how they can adversely affect crystallographic analysis.

  83. Winning the Battle of Signal vs. Noise

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    29 Aug 2014 | Teaching Materials

    James Holton (UCSF/LBNL) I will review the major sources of error that contribute to macromolecular crystallography (MX) data with a particular focus on MX data from X-ray Free Electron Lasers. The absolute limits will be defined, and the potential of new and future technologies for overcoming …

  84. WNT5A Inhibits Hepatocyte Proliferation and Concludes β-Catenin Signaling in Liver Regeneration

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    19 Jun 2015 | BioXFEL Publications | Contributor(s): Jing Yang, Antonella Cusimano, Jappmann K. Monga, Morgan E. Preziosi, Filippo Pullara, Guillermo Calero, Richard Lang, Terry P. Yamaguchi, Kari N. Nejak-Bowen, Satdarshan P. Monga

    journal-article http://dx.doi.org/10.1016/j.ajpath.2015.04.021 Yang, J. et al., 2015. WNT5A Inhibits Hepatocyte Proliferation and Concludes β-Catenin Signaling in Liver Regeneration. The American Journal of Pathology, 185(8), pp.2194–2205. Available at: …

  85. workspace

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    17 Oct 2013 | Tools

    workspace

  86. X-ray and UV radiation-damage-induced phasing using synchrotron serial crystallography

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    06 Apr 2018 | BioXFEL Publications | Contributor(s): Nicolas Foos, Carolin Seuring, Robin Schubert, Anja Burkhardt, Olof Svensson, Alke Meents, Henry Chapman, Max H. Nanao

    http://dx.doi.org/10.1107/s2059798318001535 Specific radiation damage can be used to determine phases de novo from macromolecular crystals. This method is known as radiation-damage-induced phasing (RIP). One limitation of the method is that the dose of individual data sets must be minimized, which …

  87. X-ray crystal structure of the transmembrane beta-domain from intimin from EHEC strain O157:H7

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    12 Jun 2012 | BioXFEL Publications | Contributor(s): J.W. Fairman, N. Dautin, D. Wojtowicz, L. Wei, N. Noinaj, T.J. Barnard, E. Udho, A. Finkelstein, T.M. Przytycka, V. Cherezov, S.K. Buchanan

    http://dx.doi.org/10.2210/pdb4e1s/pdb component Fairman, J.W. et al., 2012. X-ray crystal structure of the transmembrane beta-domain from intimin from EHEC strain O157:H7. Available at: http://dx.doi.org/10.2210/pdb4e1s/pdb. J.W. Fairman and N. Dautin and D. Wojtowicz and L. Wei and N. Noinaj …

  88. X-ray crystal structure of the transmembrane beta-domain from invasin from Yersinia pseudotuberculosis

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    12 Jun 2012 | BioXFEL Publications | Contributor(s): J.W. Fairman, N. Dautin, D. Wojtowicz, L. Wei, N. Noinaj, T.J. Barnard, E. Udho, A. Finkelstein, T.M. Przytycka, V. Cherezov, S.K. Buchanan

    http://dx.doi.org/10.2210/pdb4e1t/pdb component Fairman, J.W. et al., 2012. X-ray crystal structure of the transmembrane beta-domain from invasin from Yersinia pseudotuberculosis. Available at: http://dx.doi.org/10.2210/pdb4e1t/pdb. J.W. Fairman and N. Dautin and D. Wojtowicz and L. Wei and N. …

  89. X-Ray Diffraction from Isolated and Strongly Aligned Gas-Phase Molecules with a Free-Electron Laser

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    05 Mar 2014 | BioXFEL Publications | Contributor(s): Jochen Küpper, Stephan Stern, Lotte Holmegaard, Frank Filsinger, Arnaud Rouzée, Artem Rudenko, Per Johnsson, Andrew V. Martin, Marcus Adolph, Andrew Aquila, Saša Bajt, Anton Barty, Christoph Bostedt, John Bozek, Carl Caleman, Ryan Coffee, Nicola Coppola, Tjark Delmas, Sascha Epp, Benjamin Erk, Lutz Foucar, Tais Gorkhover, Lars Gumprecht, Andreas Hartmann, Robert Hartmann, Günter Hauser, Peter Holl, Andre Hömke, Nils Kimmel, Faton Krasniqi, Kai-Uwe Kühnel, Jochen Maurer, Marc Messerschmidt, Robert Moshammer, Christian Reich, Benedikt Rudek, Robin Santra, Ilme Schlichting, Carlo Schmidt, Sebastian Schorb, Joachim Schulz, Heike Soltau, John Spence, Dmitri Starodub, Lothar Strüder, Jan Thøgersen, Marc J. J. Vrakking, Georg Weidenspointner, Thomas A. White, Cornelia Wunderer, Gerard Meijer, Joachim Ullrich, Henrik Stapelfeldt, Daniel Rolles, Henry Chapman

    http://dx.doi.org/10.1103/physrevlett.112.083002 Jochen Küpper and Stephan Stern and Lotte Holmegaard and Frank Filsinger and Arnaud Rouzée and Artem Rudenko and Per Johnsson and Andrew V. Martin and Marcus Adolph and Andrew Aquila and Saša Bajt and Anton Barty and Christoph Bostedt and John …

  90. X-ray Emission Spectroscopy at X-ray Free Electron Lasers: Limits to Observation of the Classical Spectroscopic Response for Electronic Structure Analysis

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    19 Dec 2018 | BioXFEL Publications | Contributor(s): Scott C. Jensen, Brendan Sullivan, Daniel A. Hartzler, Jose Meza Aguilar, Salah Awel, Saša Bajt, Shibom Basu, Richard Bean, Henry Chapman, Chelsie E Conrad, Matthias Frank, Raimund Fromme, Jose M. Martin-Garcia, Thomas D. Grant, Michael Heymann, Mark S. Hunter, Gihan Kaushylal Ketawala, Richard Kirian, Juraj Knoska, Christopher Kupitz, Xuanxuan Li, Mengning Liang, Stella Lisova, Valerio Mariani, Victoria Mazalova, Marc Messerschmidt, Michael Moran, Garrett Charles Nelson, Dominik Oberthür, Alex Schaffer, Raymond G. Sierra, Natalie Vaughn, Uwe Weierstall, Max Oliver Wiedorn, P. Lourdu Xavier, Jay-How Yang, Oleksandr Yefanov, Nadia Zatsepin, Andrew Aquila, Petra Fromme, Sébastien Boutet, Gerald T. Seidler, Yulia Pushkar

    http://dx.doi.org/10.1021/acs.jpclett.8b03595 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Jensen, S.C. et al., 2019. X-ray Emission Spectroscopy at X-ray Free Electron Lasers: Limits to Observation of the Classical Spectroscopic Response for Electronic Structure Analysis. The …

  91. X-ray focusing with efficient high-NA multilayer Laue lenses

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    23 Mar 2018 | BioXFEL Publications | Contributor(s): Saša Bajt, Mauro Prasciolu, Holger Fleckenstein, Martin Domaracký, Henry Chapman, Andrew J Morgan, Oleksandr Yefanov, Marc Messerschmidt, Yang Du, Kevin T Murray, Valerio Mariani, Manuela Kuhn, Steven Aplin, Kanupriya Pande, Pablo Villanueva-Perez, Karolina Stachnik, Joe Chen, Andrzej Andrejczuk, Alke Meents, Anja Burkhardt, David Pennicard, Xiaojing Huang, Hanfei Yan, Evgeny Nazaretski, Yong S Chu, Christian E Hamm

    http://dx.doi.org/10.1038/lsa.2017.162 journal-article Bajt, S. et al., 2017. X-ray focusing with efficient high-NA multilayer Laue lenses. Light: Science & Applications, 7(3), p.17162. Available at: http://dx.doi.org/10.1038/lsa.2017.162. Saša Bajt and Mauro Prasciolu and Holger Fleckenstein …

  92. X-ray Free Electron Lasers

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    27 Dec 2018 | BioXFEL Publications

    http://dx.doi.org/10.1007/978-3-030-00551-1 book Boutet, S., Fromme, P. & Hunter, M.S. eds., 2018. X-ray Free Electron Lasers. Available at: http://dx.doi.org/10.1007/978-3-030-00551-1.

  93. X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex

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    11 Apr 2016 | BioXFEL Publications | Contributor(s): X. Edward Zhou, Xiang Gao, Anton Barty, Yanyong Kang, Yuanzheng He, Wei Liu, Andrii Ishchenko, Thomas A. White, Oleksandr Yefanov, Gye Won Han, Qingping Xu, Parker W. De Waal, Kelly M. Suino-Powell, Sébastien Boutet, Garth J. Williams, Meitian Wang, Dianfan Li, Martin Caffrey, Henry Chapman, John Spence, Petra Fromme, Uwe Weierstall, Raymond C. Stevens, Vadim Cherezov, Karsten Melcher, H. Eric Xu

    http://dx.doi.org/10.1038/sdata.2016.21 X. Edward Zhou and Xiang Gao and Anton Barty and Yanyong Kang and Yuanzheng He and Wei Liu and Andrii Ishchenko and Thomas A. White and Oleksandr Yefanov and Gye Won Han and Qingping Xu and Parker W. de Waal and Kelly M. Suino-Powell and Sébastien Boutet and …

  94. X-ray laser-induced electron dynamics observed by femtosecond diffraction from nanocrystals of Buckminsterfullerene

    0.0 out of 5 stars 

    09 Sep 2016 | BioXFEL Publications | Contributor(s): Brian Abbey, Ruben A. Dilanian, Connie Darmanin, Rebecca A. Ryan, Corey T. Putkunz, Andrew V. Martin, David Wood, Victor Streltsov, Michael W. M. Jones, Naylyn Gaffney, Felix Hofmann, Garth J. Williams, Sébastien Boutet, Marc Messerschmidt, M. Marvin Seibert, Sophie Williams, Evan Curwood, Eugeniu Balaur, Andrew G. Peele, Keith A. Nugent, Harry M. Quiney

    http://dx.doi.org/10.1126/sciadv.1601186 Brian Abbey and Ruben A. Dilanian and Connie Darmanin and Rebecca A. Ryan and Corey T. Putkunz and Andrew V. Martin and David Wood and Victor Streltsov and Michael W. M. Jones and Naylyn Gaffney and Felix Hofmann and Garth J. Williams and Sébastien Boutet …

  95. X-ray lasers and crystallography

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    29 Apr 2014 | BioXFEL Publications | Contributor(s): John Spence

    journal-article http://dx.doi.org/10.1107/s2052252514009567 Spence, J.C.H., 2014. X-ray lasers and crystallography. IUCrJ, 1(3), pp.151–152. Available at: http://dx.doi.org/10.1107/s2052252514009567. John C.H. Spence

  96. X-Ray Lasers in Biology

    0.0 out of 5 stars 

    24 Apr 2017 | BioXFEL Publications | Contributor(s): John Spence

    http://dx.doi.org/10.1016/bs.aiep.2017.01.008 book-chapter NSF-STC Biology with X-ray Lasers (NSF-1231306) Spence, J.C.H., 2017. X-Ray Lasers in Biology. Advances in Imaging and Electron Physics, pp.103–152. Available at: http://dx.doi.org/10.1016/bs.aiep.2017.01.008. John C.H. Spence

  97. X-ray scattering exhibits time-resolved view of rhodopsin activation

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    10 Feb 2023 | BioXFEL Publications | Contributor(s): C. Swathi K. Menon, Konstantinos Karpos, Thomas D. Grant, Andrey V. Struts, Steven D.E. Fried, Suchithranga M.D.C. Perera, Irina V. Kosheleva, Leslie Salas-Estrada, Alan Grossfield, Petra Fromme, Richard Kirian, Michael F. Brown

    http://dx.doi.org/10.1016/j.bpj.2022.11.1170 journal-article Menon, C. S. K., Karpos, K., Grant, T. D., Struts, A. V., Fried, S. D. E., Perera, S. M. D. C., Kosheleva, I. V., Salas-Estrada, L., Grossfield, A., Fromme, P., Kirian, R. A., & Brown, M. F. (2023). X-ray scattering exhibits …

  98. X-ray two-photon absorption with high fluence XFEL pulses

    0.0 out of 5 stars 

    07 Sep 2015 | BioXFEL Publications | Contributor(s): J Hoszowska, J Szlachetko, J-Cl Dousse, W Błachucki, Y Kayser, Ch Milne, M Pajek, S Boutet, M Messerschmidt, G Williams, C T Chantler

    http://dx.doi.org/10.1088/1742-6596/635/10/102009 J Hoszowska and J Szlachetko and J-Cl Dousse and W Błachucki and Y Kayser and Ch Milne and M Pajek and S Boutet and M Messerschmidt and G Williams and C T Chantler Hoszowska, J. et al., 2015. X-ray two-photon absorption with high fluence XFEL …

  99. X-ray-Based Techniques to Study the Nano–Bio Interface

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    02 Mar 2021 | BioXFEL Publications | Contributor(s): Carlos Sanchez-Cano, Ramon A. Alvarez-Puebla, John M. Abendroth, Tobias Beck, Robert Blick, Yuan Cao, Frank Caruso, Indranath Chakraborty, Henry Chapman, Chunying Chen, Bruce E. Cohen, Andre L. C. Conceição, David P. Cormode, Daxiang Cui, Kenneth A. Dawson, Gerald Falkenberg, Chunhai Fan, Neus Feliu, Mingyuan Gao, Elisabetta Gargioni, Claus-C. Glüer, Florian Grüner, Moustapha Hassan, Yong Hu, Yalan Huang, Samuel Huber, Nils Huse, Yanan Kang, Ali Khademhosseini, Thomas F. Keller, Christian Körnig, Nicholas A. Kotov, Dorota Koziej, Xing-Jie Liang, Beibei Liu, Sijin Liu, Yang Liu, Ziyao Liu, Luis M. Liz-Marzán, Xiaowei Ma, Andres Machicote, Wolfgang Maison, Adrian P. Mancuso, Saad Megahed, Bert Nickel, Ferdinand Otto, Cristina Palencia, Sakura Pascarelli, Arwen Pearson, Oula Peñate-Medina, Bing Qi, Joachim Rädler, Joseph J. Richardson, Axel Rosenhahn, Kai Rothkamm, Michael Rübhausen, Milan K. Sanyal, Raymond E. Schaak, Heinz-Peter Schlemmer, Marius Schmidt, Oliver Schmutzler, Theo Schotten, Florian Schulz, A. K. Sood, Kathryn M. Spiers, Theresa Staufer, Dominik M. Stemer, Andreas Stierle, Xing Sun, Gohar Tsakanova, Paul S. Weiss, Horst Weller, Fabian Westermeier, Ming Xu, Huijie Yan, Yuan Zeng, Ying Zhao, Yuliang Zhao, Dingcheng Zhu, Ying Zhu, Wolfgang J. Parak

    http://dx.doi.org/10.1021/acsnano.0c09563 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Sanchez-Cano, C. et al., 2021. X-ray-Based Techniques to Study the Nano–Bio Interface. ACS Nano, 15(3), pp.3754–3807. Available at: http://dx.doi.org/10.1021/acsnano.0c09563. Carlos …

  100. XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia

    0.0 out of 5 stars 

    09 Mar 2020 | BioXFEL Publications | Contributor(s): James D Zook, Mrinal Shekhar, Debra Hansen, Chelsie E Conrad, Thomas Grant, Chitrak Gupta, Thomas White, Anton Barty, Shibom Basu, Yun Zhao, Nadia Zatsepin, Andrii Ishchenko, Alex Batyuk, Cornelius Gati, Chufeng Li, Lorenzo Galli, Jesse David Coe, Mark S. Hunter, Meng Liang, Uwe Weierstall, Garret Nelson, Daniel James, Benjamin Stauch, Felicia Craciunescu, Darren Gary Thifault, Wei Liu, Vadim Cherezov, Abhishek Singharoy, Petra Fromme

    http://dx.doi.org/10.1016/j.str.2020.02.005 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Zook, J. et al., 2020. XFEL and NMR Structures of Francisella Lipoprotein Reveal Conformational Space of Drug Target against Tularemia. Structure. Available at: …