Resources: All

Submit a resource

Finding a resource

Use the sorting or filtering options to sort results and/or narrow down the list of resources.

Use the 'Search' to find specific resources by title or description.

Popular Tags

  1. animals
  2. Cheetah
  3. chemistry
  4. crystallography
  5. Data Analysis
  6. electrons
  7. instrumentation
  8. lasers
  9. LCLS
  10. methods
  11. models
  12. molecular
  13. nanoparticles
  14. protein conformation
  15. proteins
  16. radiation effects
  17. scattering
  18. time factors
  19. x-ray
  20. x-ray diffraction

Click a tag to see only resources with that tag.

Search for Courses

  1. The Gamification of XFEL Education Using XFEL Crystal Blaster

    0.0 out of 5 stars 

    06 May 2022 | BioXFEL Publications | Contributor(s): Fiacre Kabayiza, Sarah Woodruff, William J. Bauer

    http://dx.doi.org/10.3390/cryst12050671 Novel groundbreaking techniques, such as serial femtosecond crystallography (SFX), which utilizes X-ray free-electron lasers (XFELs), have led to impressive advances in the field of structural biology. However, educating the next generation of scientists on …

  2. The ideal crystal for structural biology

    0.0 out of 5 stars 

    21 Oct 2021 | BioXFEL Publications | Contributor(s): Edward Snell, Diana Monteiro, Sarah EJ Bowman

    http://dx.doi.org/10.1107/s0108767321098901 journal-article Snell, E., Monteiro, D., & Bowman, S. (2021). The ideal crystal for structural biology. Acta Crystallographica Section A Foundations and Advances, 77(a1), a109–a109. https://doi.org/10.1107/s0108767321098901 Edward Snell and Diana …

  3. The impact of base stacking on the conformations and electrostatics of single-stranded DNA

    0.0 out of 5 stars 

    17 Feb 2017 | BioXFEL Publications | Contributor(s): Alex Plumridge, Steve P. Meisburger, Kurt Andresen, Lois Pollack

    http://dx.doi.org/10.1093/nar/gkx140 journal-article Plumridge, A. et al., 2017. The impact of base stacking on the conformations and electrostatics of single-stranded DNA. Nucleic Acids Research. Available at: http://dx.doi.org/10.1093/nar/gkx140. Alex Plumridge and Steve P. Meisburger and Kurt …

  4. The impact of library size and scale of testing on virtual screening

    0.0 out of 5 stars 

    03 Jan 2025 | BioXFEL Publications | Contributor(s): Fangyu Liu, Olivier Mailhot, Isabella S. Glenn, Seth F. Vigneron, Violla Bassim, Xinyu Xu, Karla Fonseca-Valencia, Matthew S. Smith, Dmytro S. Radchenko, James Fraser, Yurii S. Moroz, John J. Irwin, Brian K. Shoichet

    https://doi.org/10.1038/s41589-024-01797-w journal-article Liu, F., Mailhot, O., Glenn, I. S., Vigneron, S. F., Bassim, V., Xu, X., Fonseca-Valencia, K., Smith, M. S., Radchenko, D. S., Fraser, J. S., Moroz, Y. S., Irwin, J. J., & Shoichet, B. K. (2025). The impact of library size and scale of …

  5. The Importance of Ligand-Receptor Conformational Pairs in Stabilization: Spotlight on the N/OFQ G Protein-Coupled Receptor

    0.0 out of 5 stars 

    03 Nov 2015 | BioXFEL Publications | Contributor(s): Rebecca L. Miller, Aaron A. Thompson, Claudio Trapella, Remo Guerrini, Davide Malfacini, Nilkanth N Patel, Gye Won Han, Vadim Cherezov, Girolamo Caló, Vsevolod Katritch, Raymond C. Stevens

    http://dx.doi.org/10.1016/j.str.2015.07.024 Rebecca L. Miller and Aaron A. Thompson and Claudio Trapella and Remo Guerrini and Davide Malfacini and Nilkanth Patel and Gye Won Han and Vadim Cherezov and Girolamo Caló and Vsevolod Katritch and Raymond C. Stevens Miller, R.L. et al., 2015. The …

  6. The indexing ambiguity in serial femtosecond crystallography (SFX) resolved using an expectation maximization algorithm

    0.0 out of 5 stars 

    23 Sep 2014 | BioXFEL Publications | Contributor(s): Haiguang Liu, John Spence

    Crystallographic auto-indexing algorithms provide crystal orientations and unit-cell parameters and assign Miller indices based on the geometric relations between the Bragg peaks observed in diffraction patterns. However, if the Bravais symmetry is higher than the space-group symmetry, there will …

  7. The influence of promiscuous metals on metalloprotein structure: complementary techniques to separate the good, the bad and the ugly

    0.0 out of 5 stars 

    19 Dec 2017 | BioXFEL Publications | Contributor(s): Edward Snell, M. Elizabeth Snell, Oliver B. Zeldin, Geoffrey W. Grime, Elspeth F. Garman

    http://dx.doi.org/10.1107/s0108767317097677 journal-article Snell, E.H. et al., 2017. The influence of promiscuous metals on metalloprotein structure: complementary techniques to separate the good, the bad and the ugly. Acta Crystallographica Section A Foundations and Advances, 73(a1), …

  8. The Interplay between Molten Globules and Heme Disassociation Defines Human Hemoglobin Disassembly

    0.0 out of 5 stars 

    04 Feb 2020 | BioXFEL Publications | Contributor(s): Premila P. Samuel, Mark A. White, William C. Ou, David Case, George Phillips, John S. Olson

    http://dx.doi.org/10.1016/j.bpj.2020.01.031 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Samuel, P.P. et al., 2020. The Interplay between Molten Globules and Heme Disassociation Defines Human Hemoglobin Disassembly. Biophysical Journal, 118(6), pp.1381–1400. Available at: …

  9. The ligand-bound state of a G protein-coupled receptor stabilizes the interaction of functional cholesterol molecules

    0.0 out of 5 stars 

    26 Feb 2021 | BioXFEL Publications | Contributor(s): Laura Lemel, Katarzyna Nieścierowicz, M. Dolores García-Fernández, Leonardo Darré, Thierry Durroux, Marta Busnelli, Mylène Pezet, Fabrice Rébeillé, Juliette Jouhet, Bernard Mouillac, Carmen Domene, Bice Chini, Vadim Cherezov, Christophe J. Moreau

    http://dx.doi.org/10.1016/j.jlr.2021.100059 journal-article Lemel, L. et al., 2021. The ligand-bound state of a G protein-coupled receptor stabilizes the interaction of functional cholesterol molecules. Journal of Lipid Research, 62, p.100059. Available at: …

  10. The linac coherent light source single particle imaging road map

    0.0 out of 5 stars 

    21 Apr 2015 | BioXFEL Publications | Contributor(s): A. Aquila, A. Barty, C. Bostedt, S. Boutet, G. Carini, D. DePonte, P. Drell, S. Doniach, K. H. Downing, T. Earnest, H. Elmlund, V. Elser, M. Gühr, J. Hajdu, J. Hastings, S. P. Hau-Riege, Z. Huang, E. E. Lattman, F. R. N. C. Maia, S. Marchesini, A. Ourmazd, C. Pellegrini, R. Santra, I. Schlichting, C. Schroer, J. C. H. Spence, I. A. Vartanyants, S. Wakatsuki, W. I. Weis, G. J. Williams

    http://dx.doi.org/10.1063/1.4918726 A. Aquila and A. Barty and C. Bostedt and S. Boutet and G. Carini and D. dePonte and P. Drell and S. Doniach and K. H. Downing and T. Earnest and H. Elmlund and V. Elser and M. Gühr and J. Hajdu and J. Hastings and S. P. Hau-Riege and Z. Huang and E. E. Lattman …

  11. The lipid phase preference of the adenosine A2A receptor depends on its ligand binding state

    0.0 out of 5 stars 

    30 Apr 2019 | BioXFEL Publications | Contributor(s): M. Gertrude Gutierrez, Jacob Deyell, Kate L. White, Lucia C. Dalle Ore, Vadim Cherezov, Raymond C. Stevens, Noah Malmstadt

    http://dx.doi.org/10.1039/c8cc10130b As cholesterol fraction increases, ligand-bound receptor occupies more vesicle surface area, demonstrating co-localization with the cholesterol-rich phase. journal-article Gutierrez, M.G. et al., 2019. The lipid phase preference of the adenosine A2A receptor …

  12. The Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source

    0.0 out of 5 stars 

    22 Feb 2019 | BioXFEL Publications | Contributor(s): Raymond G. Sierra, Alexander Batyuk, Zhibin Sun, Andrew Aquila, Mark S. Hunter, Thomas J. Lane, Mengning Liang, Chun Hong Yoon, Roberto Alonso-Mori, Rebecca Armenta, Jean-Charles Castagna, Michael Hollenbeck, Ted O. Osier, Matt Hayes, Jeff Aldrich, Robin Curtis, Jason E. Koglin, Theodore Rendahl, Evan Rodriguez, Sergio Carbajo, Serge Guillet, Rob Paul, Philip Hart, Kazutaka Nakahara, Gabriella Carini, Hasan Demirci, E. Han Dao, Brandon Hayes, Yashas P. Rao, Matthieu Chollet, Yiping Feng, Franklin D. Fuller, Christopher Kupitz, Takahiro Sato, Matthew H. Seaberg, Sanghoon Song, Tim B. Van Driel, Hasan Yavas, Diling Zhu, Aina E. Cohen, Soichi Wakatsuki, Sébastien Boutet

    http://dx.doi.org/10.1107/s1600577519001577 The Macromolecular Femtosecond Crystallography (MFX) instrument at the Linac Coherent Light Source (LCLS) is the seventh and newest instrument at the world's first hard X-ray free-electron laser. It was designed with a primary focus on structural biology, …

  13. The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature

    0.0 out of 5 stars 

    27 May 2022 | BioXFEL Publications | Contributor(s): Galen J. Correy, Daniel W. Kneller, Gwyndalyn Phillips, Swati Pant, Silvia Russi, Aina E. Cohen, George Meigs, James Holton, Stefan Gahbauer, Michael Thompson, Alan Ashworth, Leighton Coates, Andrey Kovalevsky, Flora Meilleur, James Fraser

    http://dx.doi.org/10.1126/sciadv.abo5083 The nonstructural protein 3 (NSP3) macrodomain of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (Mac1) removes adenosine diphosphate (ADP) ribosylation posttranslational modifications, playing a key role in the immune evasion capabilities of …

  14. The mythical metal – insights on the accuracy of metal identification in structural biology

    0.0 out of 5 stars 

    26 Sep 2023 | BioXFEL Publications | Contributor(s): Edward Snell, Elspeth F. Garman, Geoff W. Grime, Aina E. Cohen, Sarah EJ Bowman

    http://dx.doi.org/10.1107/s2053273323097188 journal-article Snell, E. H., Garman, E. F., Grime, G. W., Cohen, A. E., & Bowman, S. E. J. (2023). The mythical metal – insights on the accuracy of metal identification in structural biology. Acta Crystallographica Section A Foundations and Advances, …

  15. The neutralization effect of montelukast on SARS-CoV-2 is shown by multiscale in silico simulations and combined in vitro studies

    0.0 out of 5 stars 

    22 Oct 2021 | BioXFEL Publications | Contributor(s): Serdar Durdagi, Timucin Avsar, Muge Didem Orhan, Muge Serhatli, Bertan Koray Balcioglu, Hasan Umit Ozturk, Alisan Kayabolen, Yuksel Cetin, Seyma Aydinlik, Tugba Bagci-Onder, Saban Tekin, Hasan Demirci, Mustafa Guzel, Atilla Akdemir, Seyma Calis, Lalehan Oktay, Ilayda Tolu, Yasar Enes Butun, Ece Erdemoglu, Alpsu Olkan, Nurettin Tokay, Şeyma Işık, Aysenur Ozcan, Elif Acar, Sehriban Buyukkilic, Yesim Yumak

    http://dx.doi.org/10.1016/j.ymthe.2021.10.014 journal-article Durdagi, S., Avsar, T., Orhan, M. D., Serhatli, M., Balcioglu, B. K., Ozturk, H. U., Kayabolen, A., Cetin, Y., Aydinlik, S., Bagci-Onder, T., Tekin, S., Demirci, H., Guzel, M., Akdemir, A., Calis, S., Oktay, L., Tolu, I., Butun, Y. E., …

  16. The phase problem for two-dimensional crystals. II. Simulations

    0.0 out of 5 stars 

    03 Sep 2018 | BioXFEL Publications | Contributor(s): Romain D. Arnal, Yun Zhao, Alok K. Mitra, John Spence, Rick P. Millane

    http://dx.doi.org/10.1107/s2053273318008707 Phasing of diffraction data from two-dimensional crystals using only minimal molecular envelope information is investigated by simulation. Two-dimensional crystals are an attractive target for studying membrane proteins using X-ray free-electron lasers, …

  17. The Pixel Anomaly Detection Tool: a user-friendly GUI for classifying detector frames using machine-learning approaches

    0.0 out of 5 stars 

    12 Feb 2024 | BioXFEL Publications | Contributor(s): Gihan Kaushylal Ketawala, Caitlin M. Reiter, Petra Fromme, Sabine Botha

    http://dx.doi.org/10.1107/s1600576724000116 Data collection at X-ray free electron lasers has particular experimental challenges, such as continuous sample delivery or the use of novel ultrafast high-dynamic-range gain-switching X-ray detectors. This can result in a multitude of data artefacts, …

  18. The primary structural photoresponse of phytochrome proteins captured by a femtosecond X-ray laser

    0.0 out of 5 stars 

    30 Mar 2020 | BioXFEL Publications | Contributor(s): Elin Claesson, Weixiao Yuan Wahlgren, Heikki Takala, Suraj Pandey, Leticia Castillon, Valentyna Kuznetsova, Léocadie Henry, Matthijs Panman, Melissa Carrillo, Joachim Kübel, Rahul Nanekar, Linnéa Isaksson, Amke Nimmrich, Andrea Cellini, Dmitry Morozov, Michał Maj, Moona Kurttila, Robert William Bosman, Eriko Nango, Rie Tanaka, Tomoyuki Tanaka, Luo Fangjia, So Iwata, Shigeki Owada, Keith Moffat, Gerrit Groenhof, Emina Stojkovic, Janne A Ihalainen, Marius Schmidt, Sebastian Westenhoff

    http://dx.doi.org/10.7554/elife.53514 Phytochrome proteins control the growth, reproduction, and photosynthesis of plants, fungi, and bacteria. Light is detected by a bilin cofactor, but it remains elusive how this leads to activation of the protein through structural changes. We present serial …

  19. The Role of Correlation and Solvation in Ion Interactions with B-DNA

    0.0 out of 5 stars 

    19 Jan 2016 | BioXFEL Publications | Contributor(s): Maria L. Sushko, Dennis G. Thomas, Suzette A. Pabit, Lois Pollack, Alexey V. Onufriev, Nathan A. Baker

    journal-article http://dx.doi.org/10.1016/j.bpj.2015.12.011 Sushko, M.L. et al., 2016. The Role of Correlation and Solvation in Ion Interactions with B-DNA. Biophysical Journal, 110(2), pp.315–326. Available at: http://dx.doi.org/10.1016/j.bpj.2015.12.011. Maria L. Sushko and Dennis G. Thomas …

  20. The room temperature crystal structure of a bacterial phytochrome determined by serial femtosecond crystallography

    0.0 out of 5 stars 

    19 Oct 2016 | BioXFEL Publications | Contributor(s): Petra Edlund, Heikki Takala, Elin Claesson, Léocadie Henry, Robert Dods, Heli Lehtivuori, Matthijs Panman, Kanupriya Pande, Thomas White, Takanori Nakane, Oskar Berntsson, Emil Gustavsson, Petra Båth, Vaibhav Modi, Shatabdi Roy-Chowdhury, James D Zook, Peter Berntsen, Suraj Pandey, Ishwor Poudyal, Jason Tenboer, Christopher Kupitz, Anton Barty, Petra Fromme, Jake D. Koralek, Tomoyuki Tanaka, John Spence, Mengning Liang, Mark S. Hunter, Sebastien Boutet, Eriko Nango, Keith Moffat, Gerrit Groenhof, Janne Ihalainen, Emina A. Stojković, Marius Schmidt, Sebastian Westenhoff

    http://dx.doi.org/10.1038/srep35279 Petra Edlund and Heikki Takala and Elin Claesson and Léocadie Henry and Robert Dods and Heli Lehtivuori and Matthijs Panman and Kanupriya Pande and Thomas White and Takanori Nakane and Oskar Berntsson and Emil Gustavsson and Petra Båth and Vaibhav Modi and …

  21. The Single Particles, Clusters and Biomolecules and Serial Femtosecond Crystallography instrument of the European XFEL: initial installation

    0.0 out of 5 stars 

    12 Apr 2019 | BioXFEL Publications | Contributor(s): Adrian P. Mancuso, Andrew Aquila, Lewis Batchelor, Richard J. Bean, Johan Bielecki, Gannon Borchers, Katerina Doerner, Klaus Giewekemeyer, Rita Graceffa, Oliver D. Kelsey, Yoonhee Kim, Henry J. Kirkwood, Alexis Legrand, Romain Letrun, Bradley Manning, Luis Lopez Morillo, Marc Messerschmidt, Grant Mills, Steffen Raabe, Nadja Reimers, Adam Round, Tokushi Sato, Joachim Schulz, Cedric Signe Takem, Marcin Sikorski, Stephan Stern, Prasad Thute, Patrik Vagovič, Britta Weinhausen, Thomas Tschentscher

    http://dx.doi.org/10.1107/s1600577519003308 The European X-ray Free-Electron Laser (FEL) became the first operational high-repetition-rate hard X-ray FEL with first lasing in May 2017. Biological structure determination has already benefitted from the unique properties and capabilities of X-ray …

  22. The Structural History of RNA Polymerase Transcription Machinery

    0.0 out of 5 stars 

    18 Feb 2016 | Teaching Materials | Contributor(s): Roger Kornberg

    Dr. Roger Kornberg, 2006 Nobel Laureate in Chemistry, discusses the structural history of the RNA polymerase II transcription machinery and how it played a role in his successful career.

  23. The structural plasticity of nucleic acid duplexes revealed by WAXS and MD

    0.0 out of 5 stars 

    23 Apr 2021 | BioXFEL Publications | Contributor(s): Weiwei He, Yen-Lin Chen, Lois Pollack, Serdal Kirmizialtin

    http://dx.doi.org/10.1126/sciadv.abf6106 Double-stranded DNA (dsDNA) and RNA (dsRNA) helices display an unusual structural diversity. Some structural variations are linked to sequence and may serve as signaling units for protein-binding partners. Therefore, elucidating the mechanisms and factors …

  24. The Structure of the PanD/PanZ Protein Complex Reveals Negative Feedback Regulation of Pantothenate Biosynthesis by Coenzyme A

    0.0 out of 5 stars 

    23 Apr 2015 | BioXFEL Publications | Contributor(s): Diana C.F. Monteiro, Vijay Patel, Christopher P. Bartlett, Shingo Nozaki, Thomas D. Grant, James A. Gowdy, Gary S. Thompson, Arnout P. Kalverda, Edward H. Snell, Hironori Niki, Arwen R. Pearson, Michael E. Webb

    http://dx.doi.org/10.1016/j.chembiol.2015.03.017 Diana C.F. Monteiro and Vijay Patel and Christopher P. Bartlett and Shingo Nozaki and Thomas D. Grant and James A. Gowdy and Gary S. Thompson and Arnout P. Kalverda and Edward H. Snell and Hironori Niki and Arwen R. Pearson and Michael E. …

  25. The three-dimensional structure of Drosophila melanogaster (6–4) photolyase at room temperature

    0.0 out of 5 stars 

    29 Jul 2021 | BioXFEL Publications | Contributor(s): Andrea Cellini, Weixiao Yuan Wahlgren, Léocadie Henry, Suraj Pandey, Swagatha Ghosh, Leticia Castillon, Elin Claesson, Heikki Takala, Joachim Kübel, Amke Nimmrich, Valentyna Kuznetsova, Eriko Nango, So Iwata, Shigeki Owada, Emina Stojkovic, Marius Schmidt, Janne A. Ihalainen, Sebastian Westenhoff

    http://dx.doi.org/10.1107/s2059798321005830 (6–4) photolyases are flavoproteins that belong to the photolyase/cryptochrome family. Their function is to repair DNA lesions using visible light. Here, crystal structures of Drosophila melanogaster (6–4) photolyase [Dm(6–4)photolyase] at room and …

  26. The use of haptic interfaces and web services in crystallography: an application for a `screen to beam' interface

    0.0 out of 5 stars 

    11 Nov 2016 | BioXFEL Publications | Contributor(s): Andrew E. Bruno, Alexei S. Soares, Robin L. Owen, Edward Snell

    http://dx.doi.org/10.1107/s160057671601431x Haptic interfaces have become common in consumer electronics. They enable easy interaction and information entry without the use of a mouse or keyboard. The work presented here illustrates the application of a haptic interface to crystallization screening …

  27. The XBI BioLab for life science experiments at the European XFEL

    0.0 out of 5 stars 

    02 Dec 2020 | BioXFEL Publications | Contributor(s): Huijong Han, Ekaterina Round, Robin Schubert, Yasmin Gül, Jana Makroczyová, Domingo Meza, Philipp Heuser, Martin Aepfelbacher, Imrich Barák, Christian Betzel, Petra Fromme, Inari Kursula, Poul Nissen, Elena Tereschenko, Joachim Schulz, Charlotte Uetrecht, Jozef Uličný, Matthias Wilmanns, Janos Hajdu, Victor S. Lamzin, Kristina Lorenzen

    http://dx.doi.org/10.1107/s1600576720013989 The science of X-ray free-electron lasers (XFELs) critically depends on the performance of the X-ray laser and on the quality of the samples placed into the X-ray beam. The stability of biological samples is limited and key biomolecular transformations …

  28. Thermal x-ray diffraction and near-field phase contrast imaging

    0.0 out of 5 stars 

    27 Dec 2017 | BioXFEL Publications | Contributor(s): Zheng Li, Anton Classen, Tao Peng, Nikita Medvedev, Fenglin Wang, Henry Chapman, Yanhua Shih

    http://dx.doi.org/10.1209/0295-5075/120/16003 journal-article Li, Z. et al., 2017. Thermal x-ray diffraction and near-field phase contrast imaging. EPL (Europhysics Letters), 120(1), p.16003. Available at: http://dx.doi.org/10.1209/0295-5075/120/16003. Zheng Li and Anton Classen and Tao Peng and …

  29. Three-Dimensional Reconstruction of the Giant Mimivirus Particle with an X-Ray Free-Electron Laser

    0.0 out of 5 stars 

    02 Mar 2015 | BioXFEL Publications | Contributor(s): Tomas Ekeberg, Martin Svenda, Chantal Abergel, Filipe R. N. C. Maia, Virginie Seltzer, Jean-Michel Claverie, Max Hantke, Olof Jönsson, Carl Nettelblad, Gijs Van Der Schot, Mengning Liang, Daniel P. DePonte, Anton Barty, M. Marvin Seibert, Bianca Iwan, Inger Andersson, N. Duane Loh, Andrew V. Martin, Henry Chapman, Christoph Bostedt, John D. Bozek, Ken R. Ferguson, Jacek Krzywinski, Sascha W. Epp, Daniel Rolles, Artem Rudenko, Robert Hartmann, Nils Kimmel, Janos Hajdu

    http://dx.doi.org/10.1103/physrevlett.114.098102 Tomas Ekeberg and Martin Svenda and Chantal Abergel and Filipe R. N. C. Maia and Virginie Seltzer and Jean-Michel Claverie and Max Hantke and Olof Jönsson and Carl Nettelblad and Gijs van der Schot and Mengning Liang and Daniel P. DePonte and …

  30. Three-dimensional single-particle imaging using angular correlations from X-ray laser data

    0.0 out of 5 stars 

    07 May 2013 | BioXFEL Publications | Contributor(s): Haiguang Liu, Billy K. Poon, Dilano Saldin, John Spence, Peter H. Zwart

    http://dx.doi.org/10.1107/s0108767313006016 journal-article Liu, H. et al., 2013. Three-dimensional single-particle imaging using angular correlations from X-ray laser data. Acta Crystallographica Section A Foundations of Crystallography, 69(4), pp.365–373. Available at: …

  31. Three-dimensional-printed gas dynamic virtual nozzles for x-ray laser sample delivery

    0.0 out of 5 stars 

    18 May 2016 | BioXFEL Publications | Contributor(s): Garrett Charles Nelson, Richard Kirian, Uwe Weierstall, Nadia Zatsepin, Tomáš Faragó, Tilo Baumbach, Fabian Wilde, Fabian B. P. Niesler, Benjamin Zimmer, Izumi Ishigami, Masahide Hikita, Saša Bajt, Syun-Ru Yeh, Denis L. Rousseau, Henry Chapman, John Spence, Michael Heymann

    http://dx.doi.org/10.1364/oe.24.011515 Garrett Nelson and Richard A. Kirian and Uwe Weierstall and Nadia A. Zatsepin and Tomáš Faragó and Tilo Baumbach and Fabian Wilde and Fabian B. P. Niesler and Benjamin Zimmer and Izumi Ishigami and Masahide Hikita and Saša Bajt and Syun-Ru Yeh and Denis L. …

  32. Time-Resolved Contrast Variation SAXS for Studying RNA-Protein Interactions

    0.0 out of 5 stars 

    15 Feb 2019 | BioXFEL Publications | Contributor(s): Suzette A. Pabit, Andrea Katz, George Douglas Calvey, Lois Pollack

    http://dx.doi.org/10.1016/j.bpj.2018.11.1733 poster Pabit, S.A. et al., 2019. Time-Resolved Contrast Variation SAXS for Studying RNA-Protein Interactions. Biophysical Journal, 116(3), p.319a–320a. Available at: http://dx.doi.org/10.1016/j.bpj.2018.11.1733. Suzette A. Pabit and Andrea M. Katz …

  33. Time-resolved cryogenic electron tomography for the study of transient cellular processes

    0.0 out of 5 stars 

    08 May 2024 | BioXFEL Publications | Contributor(s): Joseph Yoniles, Jacob A. Summers, Kara Zielinski, Cali Antolini, Mayura Panjalingam, Stella Lisova, Frank R. Moss, Maximus Aldo Di Perna, Christopher Kupitz, Mark S. Hunter, Lois Pollack, Soichi Wakatsuki, Peter D. Dahlberg

    http://dx.doi.org/10.1091/mbc.e24-01-0042 Cryogenic electron tomography (cryo-ET) is the highest resolution imaging technique applicable to the life sciences, enabling subnanometer visualization of specimens preserved in their near native states. The rapid plunge freezing process used to prepare …

  34. Time-resolved cryogenic electron tomography for the study of transient cellular processes

    0.0 out of 5 stars 

    08 May 2024 | BioXFEL Publications | Contributor(s): Joseph Yoniles, Jacob A. Summers, Kara Zielinski, Cali Antolini, Mayura Panjalingam, Stella Lisova, Frank R. Moss, Maximus Aldo Di Perna, Christopher Kupitz, Mark S. Hunter, Lois Pollack, Soichi Wakatsuki, Peter D. Dahlberg

    https://doi.org/10.1091/mbc.e24-01-0042 Cryogenic electron tomography (cryo-ET) is the highest resolution imaging technique applicable to the life sciences, enabling subnanometer visualization of specimens preserved in their near native states. The rapid plunge freezing process used to prepare …

  35. Time-resolved cryogenic electron tomography using mix-and-inject microfluidic devices

    0.0 out of 5 stars 

    10 Apr 2025 | BioXFEL Publications | Contributor(s): Peter Dahlberg, Joey Yoniles, Jacob Summers, Kara Zielinski, Cali Antolini, Mayura Panjalingam, Stella Lisova, Frank Moss, Maximus Perna, Christopher Kupitz, Mark S. Hunter, Lois Pollack, Soichi Wakatsuki

    https://doi.org/10.1063/4.0000362 Cryogenic electron tomography (cryo-ET) is the highest resolution three-dimensional imaging technique applicable to the life sciences, enabling sub-nanometer visualization of rapidly frozen biological specimens preserved in their near native states. The rapid …

  36. Time-Resolved Crystallography at X-ray Free Electron Lasers and Synchrotron Light Sources

    0.0 out of 5 stars 

    09 Dec 2015 | BioXFEL Publications | Contributor(s): Marius Schmidt

    http://dx.doi.org/10.1080/08940886.2015.1101324 Marius Schmidt Schmidt, M., 2015. Time-Resolved Crystallography at X-ray Free Electron Lasers and Synchrotron Light Sources. Synchrotron Radiation News, 28(6), pp.25–30. Available at: http://dx.doi.org/10.1080/08940886.2015.1101324. NSF-STC Biology …

  37. Time-resolved Crystallography on Protein Photoreceptors and Enzymes

    0.0 out of 5 stars 

    08 Dec 2023 | BioXFEL Publications | Contributor(s): Marius Schmidt

    http://dx.doi.org/10.1039/bk9781837670154-00203 Time-resolved macromolecular crystallography (TRX) unifies structure determination of biomolecules with chemical kinetics. Developed at synchrotron light sources, TRX has been transformed by serial femtosecond crystallography (SFX) at X-ray free …

  38. Time-resolved functional expansion of visual rhodopsin detected by x-ray scattering

    0.0 out of 5 stars 

    11 Feb 2022 | BioXFEL Publications | Contributor(s): C. Swathi K. Menon, Konstantinos Karpos, Thomas D. Grant, Andrey V. Struts, Steven D.E. Fried, Roberto C. Alvarez, Suchithranga M.D.C. Perera, Irina V. Kosheleva, Alan Grossfield, Petra Fromme, Richard Kirian, Michael F. Brown

    http://dx.doi.org/10.1016/j.bpj.2021.11.1313 journal-article Menon, C. S. K., Karpos, K., Grant, T. D., Struts, A. V., Fried, S. D. E., Alvarez, R. C., Perera, S. M. D. C., Kosheleva, I. V., Grossfield, A., Fromme, P., Kirian, R. A., & Brown, M. F. (2022). Time-resolved functional expansion of …

  39. Time-Resolved Macromolecular Crystallography at Modern X-Ray Sources

    0.0 out of 5 stars 

    01 Jun 2017 | BioXFEL Publications | Contributor(s): Marius Schmidt

    http://dx.doi.org/10.1007/978-1-4939-7000-1_11 book-chapter NSF-STC Biology with X-ray Lasers (NSF-1231306) Schmidt, M., 2017. Time-Resolved Macromolecular Crystallography at Modern X-Ray Sources. Protein Crystallography, pp.273–294. Available at: http://dx.doi.org/10.1007/978-1-4939-7000-1_11. …

  40. Time-resolved mixing-jet X-ray free-electron laser crystallography experiments

    0.0 out of 5 stars 

    19 Dec 2017 | BioXFEL Publications | Contributor(s): Dominik Oberthuer, Juraj Knoška, Max Oliver Wiedorn, Saša Bajt, Henry Chapman

    http://dx.doi.org/10.1107/s2053273317087393 journal-article Oberthuer, D. et al., 2017. Time-resolved mixing-jet X-ray free-electron laser crystallography experiments. Acta Crystallographica Section A Foundations and Advances, 73(a2), pp.C835–C835. Available at: …

  41. Time-resolved serial crystallography captures high-resolution intermediates of photoactive yellow protein

    0.0 out of 5 stars 

    04 Dec 2014 | BioXFEL Publications | Contributor(s): Jason Tenboer, Shibom Basu, Nadia Zatsepin, Kanupriya Pande, Despina Milathianaki, Matthias Frank, Mark S. Hunter, Sébastien Boutet, Garth J. Williams, Jason E. Koglin, Dominik Oberthuer, Michael Heymann, Christopher Kupitz, Chelsie E Conrad, Jesse David Coe, Shatabdi Roy-Chowdhury, Uwe Weierstall, Daniel James, Dingjie Wang, Thomas Grant, Anton Barty, Oleksandr Yefanov, Jennifer Scales, Cornelius Gati, Carolin Seuring, Vukica Srajer, Robert Henning, Peter Schwander, Raimund Fromme, Abbas Ourmazd, Keith Moffat, Jasper J. Van Thor, John Spence, Petra Fromme, Henry Chapman, Marius Schmidt

    http://dx.doi.org/10.1126/science.1259357 Jason Tenboer and Shibom Basu and Nadia Zatsepin and Kanupriya Pande and Despina Milathianaki and Matthias Frank and Mark Hunter and Sébastien Boutet and Garth J. Williams and Jason E. Koglin and Dominik Oberthuer and Michael Heymann and Christopher …

  42. Time-resolved serial crystallography captures high-resolution intermediates of photoactive yellow protein.

    0.0 out of 5 stars 

    05 Dec 2014 | Publications

    Authors: Tenboer, J., Basu, S., Zatsepin, N., Pande, K., Milathianaki, D., Frank, M., Hunter, M., Boutet, S., Williams, G. J., Koglin, J. E., Oberthuer, D., Heymann, M., Kupitz, C., Conrad, C., Coe, J., Roy-Chowdhury, S., Weierstall, U., James, D., Wang, D., Grant, T., Barty, A., Yefanov, O., …

  43. Time-resolved serial femtosecond crystallography at the European XFEL

    0.0 out of 5 stars 

    18 Nov 2019 | BioXFEL Publications | Contributor(s): Suraj Pandey, Richard Bean, Tokushi Sato, Ishwor Poudyal, Johan Bielecki, Jorvani Cruz Villarreal, Oleksandr Yefanov, Valerio Mariani, Thomas A. White, Christopher Kupitz, Mark S. Hunter, Mohamed H. Abdellatif, Saša Bajt, Valerii Bondar, Austin Echelmeier, Diandra Doppler, Moritz Emons, Matthias Frank, Raimund Fromme, Yaroslav Gevorkov, Gabriele Giovanetti, Man Jiang, Daihyun Kim, Yoonhee Kim, Henry Kirkwood, Anna Klimovskaia, Juraj Knoska, Faisal Hammad Mekky Koua, Romain Letrun, Stella Lisova, Luis Maia, Victoria Mazalova, Domingo Meza, Thomas Michelat, Abbas Ourmazd, Guido Palmer, Marco Ramilli, Robin Schubert, Peter Schwander, Alessandro Silenzi, Jolanta Sztuk-Dambietz, Alexandra Tolstikova, Henry Chapman, Alexandra Ros, Anton Barty, Petra Fromme, Adrian P. Mancuso, Marius Schmidt

    http://dx.doi.org/10.1038/s41592-019-0628-z journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Pandey, S. et al., 2019. Time-resolved serial femtosecond crystallography at the European XFEL. Nature Methods. Available at: http://dx.doi.org/10.1038/s41592-019-0628-z. Suraj Pandey and …

  44. Time-Resolved Spectra from Millivolt EELS Data

    0.0 out of 5 stars 

    30 May 2014 | BioXFEL Publications | Contributor(s): Chufeng Li, GANESH SUBRAMANIAN, John Spence

    http://dx.doi.org/10.1017/s1431927614000890 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Li, C., Subramanian, G. & Spence, J.C.H., 2014. Time-Resolved Spectra from Millivolt EELS Data. Microscopy and Microanalysis, 20(03), pp.837–846. Available at: …

  45. Time-resolved structural studies with serial crystallography: A new light on retinal proteins

    0.0 out of 5 stars 

    29 Jun 2015 | BioXFEL Publications | Contributor(s): Valérie Panneels, Wenting Wu, Ching-Ju Tsai, Przemek Nogly, Jan Rheinberger, Kathrin Jaeger, Gregor Cicchetti, Cornelius Gati, Leonhard M. Kick, Leonardo Sala, Guido Capitani, Chris Milne, Celestino Padeste, Bill Pedrini, Xiao-Dan Li, Jörg Standfuss, Rafael Abela, Gebhard F.X. Schertler

    journal-article http://dx.doi.org/10.1063/1.4922774 NSF-STC Biology with X-ray Lasers (NSF-1231306) Panneels, V. et al., 2015. Time-resolved structural studies with serial crystallography: A new light on retinal proteins. Structural Dynamics, 2(4), p.041718. Available at: …

  46. Toward Analysis of Proteins in Single Cells: A Quantitative Approach Employing Isobaric Tags with MALDI Mass Spectrometry Realized with a Microfluidic Platform

    0.0 out of 5 stars 

    03 Jun 2016 | BioXFEL Publications | Contributor(s): Mian Yang, Randall Nelson, Alexandra Ros

    http://dx.doi.org/10.1021/acs.analchem.5b03419 journal-article Yang, M., Nelson, R. & Ros, A., 2016. Toward Analysis of Proteins in Single Cells: A Quantitative Approach Employing Isobaric Tags with MALDI Mass Spectrometry Realized with a Microfluidic Platform. Analytical Chemistry, 88(13), …

  47. Toward atomic resolution diffractive imaging of isolated molecules with X-ray free-electron lasers

    0.0 out of 5 stars 

    15 Aug 2014 | BioXFEL Publications | Contributor(s): S. Stern, L. Holmegaard, F. Filsinger, A. Rouzée, A. Rudenko, P. Johnsson, A. V. Martin, A. Barty, C. Bostedt, J. Bozek, R. Coffee, S. Epp, B. Erk, L. Foucar, R. Hartmann, N. Kimmel, K-U. Kühnel, J. Maurer, M. Messerschmidt, B. Rudek, D. Starodub, J. Thøgersen, G. Weidenspointner, T. A. White, H. Stapelfeldt, D. Rolles, H. N. Chapman, J. Küpper

    http://dx.doi.org/10.1039/c4fd00028e S. Stern and L. Holmegaard and F. Filsinger and A. Rouzée and A. Rudenko and P. Johnsson and A. V. Martin and A. Barty and C. Bostedt and J. Bozek and R. Coffee and S. Epp and B. Erk and L. Foucar and R. Hartmann and N. Kimmel and K-U. Kühnel and J. Maurer and …

  48. Toward G protein-coupled receptor structure-based drug design using X-ray lasers

    0.0 out of 5 stars 

    24 Oct 2019 | BioXFEL Publications | Contributor(s): Andrii Ishchenko, Benjamin Stauch, Gye Won Han, Alexander Batyuk, Anna Shiriaeva, Chufeng Li, Nadia Zatsepin, Uwe Weierstall, Wei Liu, Eriko Nango, Takanori Nakane, Rie Tanaka, Kensuke Tono, Yasumasa Joti, So Iwata, Isabel Moraes, Cornelius Gati, Vadim Cherezov

    http://dx.doi.org/10.1107/s2052252519013137 Rational structure-based drug design (SBDD) relies on the availability of a large number of co-crystal structures to map the ligand-binding pocket of the target protein and use this information for lead-compound optimization via an iterative process. …

  49. Toward steering a jet of particles into an x-ray beam with optically induced forces

    0.0 out of 5 stars 

    25 Aug 2015 | BioXFEL Publications | Contributor(s): Niko Eckerskorn, Richard Bowman, Richard Kirian, Salah Awel, Max Oliver Wiedorn, Jochen Küpper, Miles J. Padgett, Henry Chapman, Andrei V. Rode

    http://dx.doi.org/10.1117/12.2191442 Niko Eckerskorn and Richard Bowman and Richard A. Kirian and Salah Awel and Max Wiedorn and Jochen Küpper and Miles J. Padgett and Henry N. Chapman and Andrei V. Rode Eckerskorn, N. et al., 2015. Toward steering a jet of particles into an x-ray beam with …

  50. Toward unsupervised single-shot diffractive imaging of heterogeneous particles using X-ray free-electron lasers

    0.0 out of 5 stars 

    14 Nov 2013 | BioXFEL Publications | Contributor(s): Hyung Joo Park, N. Duane Loh, Raymond G. Sierra, Christina Y. Hampton, Dmitri Starodub, Andrew V. Martin, Anton Barty, Andrew Aquila, Joachim Schulz, Jan Steinbrener, Robert L. Shoeman, Lukas Lomb, Stephan Kassemeyer, Christoph Bostedt, John Bozek, Sascha W. Epp, Benjamin Erk, Robert Hartmann, Daniel Rolles, Artem Rudenko, Benedikt Rudek, Lutz Foucar, Nils Kimmel, Georg Weidenspointner, Guenter Hauser, Peter Holl, Emanuele Pedersoli, Mengning Liang, Mark S. Hunter, Lars Gumprecht, Nicola Coppola, Cornelia Wunderer, Heinz Graafsma, Filipe R.N.C. Maia, Tomas Ekeberg, Max Hantke, Holger Fleckenstein, Helmut Hirsemann, Karol Nass, Herbert J. Tobias, George R. Farquar, W. Henry Benner, Stefan Hau-Riege, Christian Reich, Andreas Hartmann, Heike Soltau, Stefano Marchesini, Sasa Bajt, Miriam Barthelmess, Lothar Strueder, Joachim Ullrich, Philip Bucksbaum, Matthias Frank, Ilme Schlichting, Henry Chapman, Michael J. Bogan, Veit Elser

    journal-article http://dx.doi.org/10.1364/oe.21.028729 Park, H.J. et al., 2013. Toward unsupervised single-shot diffractive imaging of heterogeneous particles using X-ray free-electron lasers. Optics Express, 21(23), p.28729. Available at: http://dx.doi.org/10.1364/oe.21.028729. Hyung Joo Park …

  51. Towards a generalised approach for the time-resolved crystallographic study of enzymes

    0.0 out of 5 stars 

    05 Jan 2016 | BioXFEL Publications | Contributor(s): Diana C. F. Monteiro, Vijay Patel, Christopher P. Bartlett, Shingo Nozaki, Thomas D. Grant, James A. Gowdy, Gary S. Thompson, Arnout P. Kalverda, Edward Snell, Hironori Niki, Arwen R. Pearson, Michael E. Webb

    http://dx.doi.org/10.1107/s205327331509957x Diana C. F. Monteiro and Vijay Patel and Christopher P. Bartlett and Shingo Nozaki and Thomas D. Grant and James A. Gowdy and Gary S. Thompson and Arnout P. Kalverda and Edward H. Snell and Hironori Niki and Arwen R. Pearson and Michael E. Webb Monteiro, …

  52. Towards phasing using high X-ray intensity

    0.0 out of 5 stars 

    29 Sep 2015 | BioXFEL Publications | Contributor(s): Lorenzo Galli, Sang-Kil Son, Thomas R. M. Barends, Thomas A. White, Anton Barty, Sabine Botha, Sébastien Boutet, Carl Caleman, R. Bruce Doak, Max H. Nanao, Karol Nass, Robert L. Shoeman, Nicusor Timneanu, Robin Santra, Ilme Schlichting, Henry Chapman

    X-ray free-electron lasers (XFELs) show great promise for macromolecular structure determination from sub-micrometre-sized crystals, using the emerging method of serial femtosecond crystallography. The extreme brightness of the XFEL radiation can multiply ionize most, if not all, atoms in a …

  53. Towards protein-crystal centering using second-harmonic generation (SHG) microscopy

    0.0 out of 5 stars 

    18 Apr 2013 | BioXFEL Publications | Contributor(s): David J. Kissick, Christopher M. Dettmar, Michael Becker, Anne M. Mulichak, Vadim Cherezov, Stephan L. Ginell, Kevin P. Battaile, Lisa J. Keefe, Robert F. Fischetti, Garth J. Simpson

    http://dx.doi.org/10.1107/s0907444913002746 journal-article Kissick, D.J. et al., 2013. Towards protein-crystal centering using second-harmonic generation (SHG) microscopy. Acta Crystallographica Section D Biological Crystallography, 69(5), pp.843–851. Available at: …

  54. Towards RIP using free-electron laser SFX data

    0.0 out of 5 stars 

    04 Feb 2015 | BioXFEL Publications | Contributor(s): Lorenzo Galli, Sang-Kil Son, Thomas A. White, Robin Santra, Henry Chapman, Max H. Nanao

    Here, it is shown that simulated native serial femtosecond crystallography (SFX) cathepsin B data can be phased by rapid ionization of sulfur atoms. Utilizing standard software adopted for radiation-damage-induced phasing (RIP), the effects on both substructure determination and phasing of the …

  55. Towards time-resolved serial crystallography in a microfluidic device

    0.0 out of 5 stars 

    26 Jun 2015 | BioXFEL Publications | Contributor(s): Ashtamurthy S. Pawate, Vukica Šrajer, Jeremy Schieferstein, Sudipto Guha, Robert Henning, Irina Kosheleva, Marius Schmidt, Zhong Ren, Paul J. A. Kenis, Sarah Perry

    Serial methods for crystallography have the potential to enable dynamic structural studies of protein targets that have been resistant to single-crystal strategies. The use of serial data-collection strategies can circumvent challenges associated with radiation damage and repeated reaction …

  56. Toxicity of Eosinophil MBP Is Repressed by Intracellular Crystallization and Promoted by Extracellular Aggregation

    0.0 out of 5 stars 

    26 Feb 2015 | BioXFEL Publications | Contributor(s): Alice Soragni, Shida Yousefi, Christina Stoeckle, Angela B. Soriaga, Michael R. Sawaya, Evelyne Kozlowski, Inès Schmid, Susanne Radonjic-Hoesli, Sebastien Boutet, Garth J. Williams, Marc Messerschmidt, M. Marvin Seibert, Duilio Cascio, Nadia A. Zatsepin, Manfred Burghammer, Christian Riekel, Jacques-Philippe Colletier, Roland Riek, David S. Eisenberg, Hans-Uwe Simon

    http://dx.doi.org/10.1016/j.molcel.2015.01.026 Alice Soragni and Shida Yousefi and Christina Stoeckle and Angela B. Soriaga and Michael R. Sawaya and Evelyne Kozlowski and Inès Schmid and Susanne Radonjic-Hoesli and Sebastien Boutet and Garth J. Williams and Marc Messerschmidt and M. Marvin …

  57. Trace phase detection and strain characterization from serial X-ray free-electron laser crystallography of a Pr0.5Ca0.5MnO3 powder

    0.0 out of 5 stars 

    17 Nov 2014 | BioXFEL Publications | Contributor(s): Kenneth R. Beyerlein, Christian Jooss, Anton Barty, Richard Bean, Sébastien Boutet, Sarnjeet S. Dhesi, R. Bruce Doak, Michael Först, Lorenzo Galli, Richard Kirian, Joseph Kozak, Michael Lang, Roman Mankowsky, Marc Messerschmidt, John Spence, Dingjie Wang, Uwe Weierstall, Thomas A. White, Garth J. Williams, Oleksandr Yefanov, Nadia Zatsepin, Andrea Cavalleri, Henry Chapman

    http://dx.doi.org/10.1017/s0885715614001171 We report on the analysis of virtual powder-diffraction patterns from serial femtosecond crystallography (SFX) data collected at an X-ray free-electron laser. Different approaches to binning and normalizing these patterns are discussed with respect to the …

  58. Trajectories of the ribosome as a Brownian nanomachine

    0.0 out of 5 stars 

    24 Nov 2014 | BioXFEL Publications | Contributor(s): Ali Dashti, Peter Schwander, Robert Langlois, Russell Fung, Wen Li, Ahmad Hosseinizadeh, Hstau Y. Liao, Jesper Pallesen, Gyanesh Sharma, Vera A. Stupina, Anne E. Simon, Jonathan D. Dinman, Joachim Frank, Abbas Ourmazd

    http://dx.doi.org/10.1073/pnas.1419276111 Ali Dashti and Peter Schwander and Robert Langlois and Russell Fung and Wen Li and Ahmad Hosseinizadeh and Hstau Y. Liao and Jesper Pallesen and Gyanesh Sharma and Vera A. Stupina and Anne E. Simon and Jonathan D. Dinman and Joachim Frank and Abbas Ourmazd …

  59. Trajectories of the ribosome as a Brownian nanomachine

    0.0 out of 5 stars 

    12 Apr 2018 | BioXFEL Publications | Contributor(s): Ali Dashti, Peter Schwander, Robert Langlois, Russell Fung, Wen Li, Ahmad Hosseinizadeh, Hstau Y. Liao, Jesper Pallesen, Gyanesh Sharma, Vera A. Stupina, Anne E. Simon, Jonathan D. Dinman, Joachim Frank, Abbas Ourmazd

    http://dx.doi.org/10.1142/9789813234864_0048 book-chapter Dashti, A. et al., 2018. Trajectories of the ribosome as a Brownian nanomachine. Single-Particle Cryo-Electron Microscopy, pp.463–475. Available at: http://dx.doi.org/10.1142/9789813234864_0048. Ali Dashti and Peter Schwander and Robert …

  60. Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms

    0.0 out of 5 stars 

    14 Apr 2014 | BioXFEL Publications | Contributor(s): V. Schweikhard, C. Meng, K. Murakami, C. D. Kaplan, R. D. Kornberg, S. M. Block

    journal-article http://dx.doi.org/10.1073/pnas.1405181111 Schweikhard, V. et al., 2014. Transcription factors TFIIF and TFIIS promote transcript elongation by RNA polymerase II by synergistic and independent mechanisms. Proceedings of the National Academy of Sciences, 111(18), pp.6642–6647. …

  61. Transferring the entatic-state principle to copper photochemistry

    0.0 out of 5 stars 

    15 Jan 2018 | BioXFEL Publications | Contributor(s): B. Dicke, A. Hoffmann, J. Stanek, M. S. Rampp, B. Grimm-Lebsanft, F. Biebl, D. Rukser, B. Maerz, D. Göries, M. Naumova, M. Biednov, G. Neuber, A. Wetzel, S. M. Hofmann, P. Roedig, A. Meents, J. Bielecki, J. Andreasson, K. R. Beyerlein, H. N. Chapman, C. Bressler, W. Zinth, M. Rübhausen, S. Herres-Pawlis

    http://dx.doi.org/10.1038/nchem.2916 journal-article Dicke, B. et al., 2018. Transferring the entatic-state principle to copper photochemistry. Nature Chemistry. Available at: http://dx.doi.org/10.1038/nchem.2916. B. Dicke and A. Hoffmann and J. Stanek and M. S. Rampp and B. Grimm-Lebsanft and …

  62. Transient lattice contraction in the solid-to-plasma transition

    0.0 out of 5 stars 

    29 Jan 2016 | BioXFEL Publications | Contributor(s): Ken R. Ferguson, Maximilian Bucher, Tais Gorkhover, Sébastien Boutet, Hironobu Fukuzawa, Jason E. Koglin, Yoshiaki Kumagai, Alberto Lutman, Agostino Marinelli, Marc Messerschmidt, Kiyonobu Nagaya, Jim Turner, Kiyoshi Ueda, Garth J. Williams, Philip H. Bucksbaum, Christoph Bostedt

    http://dx.doi.org/10.1126/sciadv.1500837 Ken R. Ferguson and Maximilian Bucher and Tais Gorkhover and Sébastien Boutet and Hironobu Fukuzawa and Jason E. Koglin and Yoshiaki Kumagai and Alberto Lutman and Agostino Marinelli and Marc Messerschmidt and Kiyonobu Nagaya and Jim Turner and Kiyoshi Ueda …

  63. Transient state measurements on proteins by time-resolved crystallography

    0.0 out of 5 stars 

    22 Apr 2022 | BioXFEL Publications | Contributor(s): Tek Narsingh Malla, Marius Schmidt

    http://dx.doi.org/10.1016/j.sbi.2022.102376 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Malla, T. N., & Schmidt, M. (2022). Transient state measurements on proteins by time-resolved crystallography. Current Opinion in Structural Biology, 74, 102376. …

  64. Transmission electron microscopy for the evaluation and optimization of crystal growth

    0.0 out of 5 stars 

    26 Apr 2016 | BioXFEL Publications | Contributor(s): Hilary P. Stevenson, Guowu Lin, Christopher Barnes, Ieva Sutkeviciute, Troy Krzysiak, Simon C. Weiss, Shelley Reynolds, Ying Wu, Veeranagu Nagarajan, Alexander M. Makhov, Robert M Lawrence, Emily Lamm, Lisa Clark, Timothy J. Gardella, Brenda Hogue, Craig M. Ogata, Jinwoo Ahn, Angela M. Gronenborn, James F. Conway, Jean-Pierre Vilardaga, Aina E. Cohen, Guillermo Calero

    The crystallization of protein samples remains the most significant challenge in structure determination by X-ray crystallography. Here, the effectiveness of transmission electron microscopy (TEM) analysis to aid in the crystallization of biological macromolecules is demonstrated. It was found that …

  65. Tuning RNA Flexibility with Helix Length and Junction Sequence

    0.0 out of 5 stars 

    15 Dec 2015 | BioXFEL Publications | Contributor(s): Julie L. Sutton, Lois Pollack

    http://dx.doi.org/10.1016/j.bpj.2015.10.039 journal-article Sutton, J.L. & Pollack, L., 2015. Tuning RNA Flexibility with Helix Length and Junction Sequence. Biophysical Journal, 109(12), pp.2644–2653. Available at: http://dx.doi.org/10.1016/j.bpj.2015.10.039. Julie L. Sutton and Lois Pollack

  66. Turning up the heat on molecular machines with multi-temperature and temperature-jump X-ray scattering experiments

    0.0 out of 5 stars 

    21 Oct 2021 | BioXFEL Publications | Contributor(s): Michael Thompson, Alexander Wolff, Benjamin Barad, Wilson Nieves Vasquez, Nathaniel Brown, Hyun Sun Cho, Friedrich Schotte, Valentyn Stadnytskyi, Philip Anfinrud, James Fraser

    http://dx.doi.org/10.1107/s0108767321097841 journal-article Thompson, M., Wolff, A., Barad, B., Vasquez, W. N., Brown, N., Cho, H. S., Schotte, F., Stadnytskyi, V., Anfinrud, P., & Fraser, J. (2021). Turning up the heat on molecular machines with multi-temperature and temperature-jump X-ray …

  67. Two disparate ligand-binding sites in the human P2Y1 receptor

    0.0 out of 5 stars 

    30 Mar 2015 | BioXFEL Publications | Contributor(s): Dandan Zhang, Zhan-Guo Gao, Kaihua Zhang, Evgeny Kiselev, Steven Crane, Jiang Wang, Silvia Paoletta, Cuiying Yi, Limin Ma, Wenru Zhang, Gye Won Han, Hong Liu, Vadim Cherezov, Vsevolod Katritch, Hualiang Jiang, Raymond C. Stevens, Kenneth A. Jacobson, Qiang Zhao, Beili Wu

    http://dx.doi.org/10.1038/nature14287 Dandan Zhang and Zhan-Guo Gao and Kaihua Zhang and Evgeny Kiselev and Steven Crane and Jiang Wang and Silvia Paoletta and Cuiying Yi and Limin Ma and Wenru Zhang and Gye Won Han and Hong Liu and Vadim Cherezov and Vsevolod Katritch and Hualiang Jiang and …

  68. Ultrafast Membrane Protein Dynamics Revealed by X-Ray Scattering with a Femtosecond Free-Electron Laser

    0.0 out of 5 stars 

    12 Feb 2021 | BioXFEL Publications | Contributor(s): Thomas D. Grant, Suchithranga M.D.C. Perera, Leslie A. Salas-Estrada, Andrey V. Struts, Udeep Chawla, Steven D.E. Fried, Nipuna Weerasinghe, Kostantinos Karpos, Domingo Meza, Nadia Zatsepin, Alan Grossfield, Derek Mendez, Petra Fromme, Richard Kirian, Michael F. Brown

    http://dx.doi.org/10.1016/j.bpj.2020.11.1006 journal-article Grant, T.D. et al., 2021. Ultrafast Membrane Protein Dynamics Revealed by X-Ray Scattering with a Femtosecond Free-Electron Laser. Biophysical Journal, 120(3), p.133a. Available at: http://dx.doi.org/10.1016/j.bpj.2020.11.1006. Thomas …

  69. Ultrafast nonthermal heating of water initiated by an X-ray Free-Electron Laser

    0.0 out of 5 stars 

    14 May 2018 | BioXFEL Publications | Contributor(s): Kenneth R. Beyerlein, H. Olof Jönsson, Roberto Alonso-Mori, Andrew Aquila, Saša Bajt, Anton Barty, Richard Bean, Jason E. Koglin, Marc Messerschmidt, Davide Ragazzon, Dimosthenis Sokaras, Garth J. Williams, Stefan Hau-Riege, Sébastien Boutet, Henry Chapman, Nicuşor Tîmneanu, Carl Caleman

    http://dx.doi.org/10.1073/pnas.1711220115 journal-article Beyerlein, K.R. et al., 2018. Ultrafast nonthermal heating of water initiated by an X-ray Free-Electron Laser. Proceedings of the National Academy of Sciences, p.201711220. Available at: http://dx.doi.org/10.1073/pnas.1711220115. Kenneth …

  70. Ultrafast self-gating Bragg diffraction of exploding nanocrystals in an X-ray laser

    0.0 out of 5 stars 

    20 Jan 2015 | BioXFEL Publications | Contributor(s): Carl Caleman, Nicuşor Tîmneanu, Andrew V. Martin, H. Olof Jönsson, Andrew Aquila, Anton Barty, Howard A. Scott, Thomas A. White, Henry Chapman

    http://dx.doi.org/10.1364/oe.23.001213 Carl Caleman and Nicuşor Tîmneanu and Andrew V. Martin and H. Olof Jönsson and Andrew Aquila and Anton Barty and Howard A. Scott and Thomas A. White and Henry N. Chapman Caleman, C. et al., 2015. Ultrafast self-gating Bragg diffraction of exploding …

  71. Ultrafast Three-Dimensional Imaging of Lattice Dynamics in Individual Gold Nanocrystals

    0.0 out of 5 stars 

    24 May 2013 | BioXFEL Publications | Contributor(s): J. N. Clark, L. Beitra, G. Xiong, A. Higginbotham, D. M. Fritz, H. T. Lemke, D. Zhu, M. Chollet, G. J. Williams, M. Messerschmidt, B. Abbey, R. J. Harder, A. M. Korsunsky, J. S. Wark, I. K. Robinson

    http://dx.doi.org/10.1126/science.1236034 journal-article Clark, J.N. et al., 2013. Ultrafast Three-Dimensional Imaging of Lattice Dynamics in Individual Gold Nanocrystals. Science, 341(6141), pp.56–59. Available at: http://dx.doi.org/10.1126/science.1236034. J. N. Clark and L. Beitra and G. …

  72. Ultrafast X-ray probing of water structure below the homogeneous ice nucleation temperature

    0.0 out of 5 stars 

    17 Jun 2014 | BioXFEL Publications | Contributor(s): J. A. Sellberg, C. Huang, T. A. McQueen, N. D. Loh, H. Laksmono, D. Schlesinger, R. G. Sierra, D. Nordlund, C. Y. Hampton, D. Starodub, D. P. DePonte, M. Beye, C. Chen, A. V. Martin, A. Barty, K. T. Wikfeldt, T. M. Weiss, C. Caronna, J. Feldkamp, L. B. Skinner, M. M. Seibert, M. Messerschmidt, G. J. Williams, S. Boutet, L. G. M. Pettersson, M. J. Bogan, A. Nilsson

    journal-article http://dx.doi.org/10.1038/nature13266 Sellberg, J.A. et al., 2014. Ultrafast X-ray probing of water structure below the homogeneous ice nucleation temperature. Nature, 510(7505), pp.381–384. Available at: http://dx.doi.org/10.1038/nature13266. J. A. Sellberg and C. Huang and T. …

  73. Uncoupling Promoter Opening from Start-Site Scanning

    0.0 out of 5 stars 

    13 Jun 2015 | BioXFEL Publications | Contributor(s): Kenji Murakami, Pierre-Jean Mattei, Ralph E. Davis, Huiyan Jin, Craig D. Kaplan, Roger D. Kornberg

    journal-article http://dx.doi.org/10.1016/j.molcel.2015.05.021 Murakami, K. et al., 2015. Uncoupling Promoter Opening from Start-Site Scanning. Molecular Cell, 59(1), pp.133–138. Available at: http://dx.doi.org/10.1016/j.molcel.2015.05.021. Kenji Murakami and Pierre-Jean Mattei and Ralph E. …

  74. Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT fromSulfolobus solfataricus

    0.0 out of 5 stars 

    20 Mar 2014 | BioXFEL Publications | Contributor(s): Fengbin Wang, Shanteri Singh, Jianjun Zhang, Tyler D. Huber, Kate E. Helmich, Manjula Sunkara, Katherine A. Hurley, Randal D. Goff, Craig A. Bingman, Andrew J. Morris, Jon S. Thorson, George Phillips

    http://dx.doi.org/10.1111/febs.12784 journal-article Wang, F. et al., 2014. Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT fromSulfolobus solfataricus. FEBS Journal, 281(18), pp.4224–4239. Available at: …

  75. Understanding nucleic acid structural changes by comparing wide-angle x-ray scattering (WAXS) experiments to molecular dynamics simulations

    0.0 out of 5 stars 

    25 May 2016 | BioXFEL Publications | Contributor(s): Suzette A. Pabit, Andrea Katz, Igor S. Tolokh, Aleksander Drozdetski, Nathan Baker, Alexey V. Onufriev, Lois Pollack

    http://dx.doi.org/10.1063/1.4950814 journal-article Pabit, S.A. et al., 2016. Understanding nucleic acid structural changes by comparing wide-angle x-ray scattering (WAXS) experiments to molecular dynamics simulations. The Journal of Chemical Physics, 144(20), p.205102. Available at: …

  76. Unique patterns of transcript and miRNA expression in the South American strong voltage electric eel (Electrophorus electricus)

    0.0 out of 5 stars 

    25 Mar 2015 | BioXFEL Publications | Contributor(s): Lindsay L Traeger, Jeremy D Volkening, Howell Moffett, Jason R Gallant, Po-Hao Chen, Carl D Novina, George Phillips, Rene Anand, Gregg B Wells, Matthew Pinch, Robert Güth, Graciela A Unguez, James S Albert, Harold Zakon, Michael R Sussman, Manoj P Samanta

    http://dx.doi.org/10.1186/s12864-015-1288-8 Lindsay L Traeger and Jeremy D Volkening and Howell Moffett and Jason R Gallant and Po-Hao Chen and Carl D Novina and George N Phillips and Rene Anand and Gregg B Wells and Matthew Pinch and Robert Güth and Graciela A Unguez and James S Albert and Harold …

  77. Use of transmission electron microscopy to identify nanocrystals of challenging protein targets

    0.0 out of 5 stars 

    28 May 2014 | BioXFEL Publications | Contributor(s): H. P. Stevenson, A. M. Makhov, M. Calero, A. L. Edwards, O. B. Zeldin, I. I. Mathews, G. Lin, C. O. Barnes, H. Santamaria, T. M. Ross, S. M. Soltis, C. Khosla, V. Nagarajan, J. F. Conway, A. E. Cohen, G. Calero

    http://dx.doi.org/10.1073/pnas.1400240111 journal-article Stevenson, H.P. et al., 2014. Use of transmission electron microscopy to identify nanocrystals of challenging protein targets. Proceedings of the National Academy of Sciences, 111(23), pp.8470–8475. Available at: …

  78. Use of triple correlations for the sign determinations of expansion coefficients of symmetric approximations to the diffraction volumes of regular viruses

    0.0 out of 5 stars 

    18 Jun 2015 | BioXFEL Publications | Contributor(s): H. C. Poon, D. K. Saldin

    http://dx.doi.org/10.1063/1.4922476 H. C. Poon and D. K. Saldin Poon, H.C. & Saldin, D.K., 2015. Use of triple correlations for the sign determinations of expansion coefficients of symmetric approximations to the diffraction volumes of regular viruses. Structural Dynamics, 2(4), p.041716. Available …

  79. Using a commodity high-definition television for collaborative structural biology

    0.0 out of 5 stars 

    28 May 2014 | BioXFEL Publications | Contributor(s): Ragothaman Yennamalli, Raj Arangarasan, Aaron Bryden, Michael Gleicher, George Phillips

    Visualization of protein structures using stereoscopic systems is frequently needed by structural biologists working to understand a protein's structure–function relationships. Often several scientists are working as a team and need simultaneous interaction with each other and the graphics …

  80. Using deep mutational scanning to identify the determinants of antibiotic resistance

    0.0 out of 5 stars 

    11 Feb 2022 | BioXFEL Publications | Contributor(s): Christian B. Macdonald, Alexis Kelley, Jenna Pellegrino, Willow Coyote-Maestas, James Fraser

    http://dx.doi.org/10.1016/j.bpj.2021.11.665 journal-article Macdonald, C. B., Kelley, A., Pellegrino, J., Coyote-Maestas, W., & Fraser, J. (2022). Using deep mutational scanning to identify the determinants of antibiotic resistance. Biophysical Journal, 121(3), 422a. …

  81. Using Machine Learning to Achieve Accurate Estimates of Fetal Gestational Age and Personalized Predictions of Fetal Growth

    0.0 out of 5 stars 

    24 Mar 2020 | BioXFEL Publications | Contributor(s): Russell Fung, Jose Villar, Ali Dashti, Leila Cheikh Ismail, Eleonora Staines-Urias, Eric O. Ohuma, Laurent J. Salomon, Cesar G. Victora, Fernando C. Barros, Ann Lambert, Maria Carvalho, Yasmin A. Jaffer, Alison J. Noble, Michael G. Gravett, Manorama Purwar, Ruyan Pang, Enrico Bertino, Shama Munim, Aung Myat Min, Rose McGready, Shane A. Norris, Zulfiqar A Bhutta, Stephen H. Kennedy, Aris T. Papageorghiou, Abbas Ourmazd, International Fetal And Newborn Gro Group

    http://dx.doi.org/10.2139/ssrn.3471997 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Fung, R. et al., 2019. Using Machine Learning to Achieve Accurate Estimates of Fetal Gestational Age and Personalized Predictions of Fetal Growth. SSRN Electronic Journal. Available at: …

  82. Using X-ray Diffraction Techniques for Biomimetic Drug Development, Formulation, and Polymorphic Characterization

    0.0 out of 5 stars 

    30 Dec 2020 | BioXFEL Publications | Contributor(s): Israel Rodriguez, Ritika Gautam, Arthur Tinoco

    http://dx.doi.org/10.3390/biomimetics6010001 Drug development is a decades-long, multibillion dollar investment that often limits itself. To decrease the time to drug approval, efforts are focused on drug targets and drug formulation for optimal biocompatibility and efficacy. X-ray structural …

  83. Using XFELs to measure the solution structures of biomolecules

    0.0 out of 5 stars 

    13 Oct 2015 | Teaching Materials

    Dr. Lois Pollack presents an introduction to small and wide angle X-ray solution scattering techniques and describes the advances made possible by XFELs.

  84. Valence electron energy-loss spectroscopy study of ZrSiO4 and ZrO2

    0.0 out of 5 stars 

    16 Jul 2013 | BioXFEL Publications | Contributor(s): Nan Jiang, John Spence

    journal-article http://dx.doi.org/10.1016/j.ultramic.2013.06.021 Jiang, N. & Spence, J.C.H., 2013. Valence electron energy-loss spectroscopy study of ZrSiO4 and ZrO2. Ultramicroscopy, 134, pp.68–76. Available at: http://dx.doi.org/10.1016/j.ultramic.2013.06.021. Nan Jiang and John C.H. Spence

  85. Vibrational Excitations and Low-Energy Electronic Structure of Epoxide-Decorated Graphene

    0.0 out of 5 stars 

    17 Dec 2013 | BioXFEL Publications | Contributor(s): E. C. Mattson, J. E. Johns, K. Pande, R. A. Bosch, S. Cui, M. Gajdardziska-Josifovska, M. Weinert, J. H. Chen, M. C. Hersam, C. J. Hirschmugl

    journal-article http://dx.doi.org/10.1021/jz4025386 Mattson, E.C. et al., 2014. Vibrational Excitations and Low-Energy Electronic Structure of Epoxide-Decorated Graphene. The Journal of Physical Chemistry Letters, 5(1), pp.212–219. Available at: http://dx.doi.org/10.1021/jz4025386. E. C. …

  86. Viral anti‐inflammatory serpin reduces immuno‐coagulopathic pathology in SARS‐CoV‐2 mouse models of infection

    0.0 out of 5 stars 

    03 Aug 2023 | BioXFEL Publications | Contributor(s): Liqiang Zhang, Yize (Henry) Li, Karen Kibler, Simona Kraberger, Arvind Varsani, Julie Turk, Nora Elmadbouly, Emily Aliskevich, Laurel Spaccarelli, Bereket Estifanos, Junior Enow, Isabela Rivabem Zanetti, Nicholas Saldevar, Efrem Lim, Jessika Schlievert, Kyle Browder, Anjali Wilson, Fernando Arcos Juan, Aubrey Pinteric, Aman Garg, Henna Monder, Rohan Saju, Savanah Gisriel, Bertram Jacobs, Timothy L Karr, Esther Borges Florsheim, Vivek Kumar, John Wallen, Masmudur Rahman, Grant McFadden, Brenda Hogue, Alexandra R Lucas

    http://dx.doi.org/10.15252/emmm.202317376 AbstractSARS‐CoV‐2 acute respiratory distress syndrome (ARDS) induces uncontrolled lung inflammation and coagulopathy with high mortality. Anti‐viral drugs and monoclonal antibodies reduce early COVID‐19 severity, but treatments for late‐stage …

  87. Viral RNA Folding Studied through Contrast Variation Small Angle- X Ray Scattering

    0.0 out of 5 stars 

    07 Feb 2020 | BioXFEL Publications | Contributor(s): Josue San Emeterio, Lois Pollack

    http://dx.doi.org/10.1016/j.bpj.2019.11.1319 journal-article Emeterio, J. S., & Pollack, L. (2020). Viral RNA Folding Studied through Contrast Variation Small Angle- X Ray Scattering. Biophysical Journal, 118(3), 222a. https://doi.org/10.1016/j.bpj.2019.11.1319 Josue San Emeterio and Lois Pollack

  88. Virtual discovery of melatonin receptor ligands to modulate circadian rhythms

    0.0 out of 5 stars 

    10 Feb 2020 | BioXFEL Publications | Contributor(s): Reed M. Stein, Hye Jin Kang, John D. McCorvy, Grant C. Glatfelter, Anthony J. Jones, Tao Che, Samuel Slocum, Xi-Ping Huang, Olena Savych, Yurii S. Moroz, Benjamin Stauch, Linda C. Johansson, Vadim Cherezov, Terry Kenakin, John J. Irwin, Brian K. Shoichet, Bryan L. Roth, Margarita L. Dubocovich

    http://dx.doi.org/10.1038/s41586-020-2027-0 journal-article NSF-STC Biology with X-ray Lasers (NSF-1231306) Stein, R.M. et al., 2020. Virtual discovery of melatonin receptor ligands to modulate circadian rhythms. Nature. Available at: http://dx.doi.org/10.1038/s41586-020-2027-0. Reed M. Stein and …

  89. Virus Crystallography

    0.0 out of 5 stars 

    14 Oct 2015 | Teaching Materials | Contributor(s): Robert M Lawrence

    Dr. Rob Lawrence describes the unique problems associated with crystallization of virus particles and different methods to overcome them.

  90. Virus Dynamics Studied by Time-Resolved Small Angle X-Ray Scattering

    0.0 out of 5 stars 

    15 Feb 2019 | BioXFEL Publications | Contributor(s): Josue San Emeterio, Lois Pollack

    http://dx.doi.org/10.1016/j.bpj.2018.11.2321 journal-article San Emeterio, J., & Pollack, L. (2019). Virus Dynamics Studied by Time-Resolved Small Angle X-Ray Scattering. Biophysical Journal, 116(3), 431a. https://doi.org/10.1016/j.bpj.2018.11.2321 Josue San Emeterio and Lois Pollack

  91. Visualization of biomolecular structures by WAXS and MD

    0.0 out of 5 stars 

    21 Oct 2021 | BioXFEL Publications | Contributor(s): Weiwei He, Yen-Lin Chen, Serdal Kirmizialtin, Lois Pollack

    http://dx.doi.org/10.1107/s0108767321098755 journal-article He, W., Chen, Y.-L., Kirmizialtin, S., & Pollack, L. (2021). Visualization of biomolecular structures by WAXS and MD. Acta Crystallographica Section A Foundations and Advances, 77(a1), a124–a124. …

  92. Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser

    0.0 out of 5 stars 

    13 Oct 2015 | Teaching Materials

    We describe a method to measure ultrafast protein structural changes using time-resolved wide-angle X-ray scattering at an X-ray free-electron laser. We demonstrated this approach using multiphoton excitation of the Blastochloris viridis photosynthetic reaction center, observing an ultrafast …

  93. Visualizing aerosol-particle injection for diffractive-imaging experiments

    0.0 out of 5 stars 

    16 Mar 2016 | BioXFEL Publications | Contributor(s): Salah Awel, Richard Kirian, Niko Eckerskorn, Max Oliver Wiedorn, Daniel A. Horke, Andrei V. Rode, Jochen Küpper, Henry Chapman

    http://dx.doi.org/10.1364/oe.24.006507 Salah Awel and Richard A. Kirian and Niko Eckerskorn and Max Wiedorn and Daniel A. Horke and Andrei V. Rode and Jochen Küpper and Henry N. Chapman Awel, S. et al., 2016. Visualizing aerosol-particle injection for diffractive-imaging experiments. Optics …

  94. Visualizing Disordered Single-Stranded RNA: Connecting Sequence, Structure, and Electrostatics

    0.0 out of 5 stars 

    05 Dec 2019 | BioXFEL Publications | Contributor(s): Alex Plumridge, Kurt Andresen, Lois Pollack

    http://dx.doi.org/10.1021/jacs.9b04461 journal-article Plumridge, A., Andresen, K. & Pollack, L., 2019. Visualizing Disordered Single-Stranded RNA: Connecting Sequence, Structure, and Electrostatics. Journal of the American Chemical Society. Available at: http://dx.doi.org/10.1021/jacs.9b04461. …

  95. Visualizing single-stranded nucleic acids in solution

    0.0 out of 5 stars 

    13 Dec 2016 | BioXFEL Publications | Contributor(s): Alex Plumridge, Steve P. Meisburger, Lois Pollack

    http://dx.doi.org/10.1093/nar/gkw1297 journal-article Plumridge, A., Meisburger, S.P. & Pollack, L., 2016. Visualizing single-stranded nucleic acids in solution. Nucleic Acids Research, p.gkw1297. Available at: http://dx.doi.org/10.1093/nar/gkw1297. Alex Plumridge and Steve P. Meisburger and …

  96. Vitamin C Binds to SARS Coronavirus-2 Main Protease Essential for Viral Replication

    0.0 out of 5 stars 

    04 May 2021 | BioXFEL Publications | Contributor(s): Tek Narsingh Malla, Suraj Pandey, Luis Aldama, Dennisse Feliz, Moraima Noda, Ishwor Poudyal, George Phillips, Emina Stojkovic, Marius Schmidt

    http://dx.doi.org/10.1101/2021.05.02.442358 AbstractThere is an urgent need for anti-viral agents that treat and/or prevent Covid-19 caused by SARS-Coronavirus (CoV-2) infections. The replication of the SARS CoV-2 is dependent on the activity of two cysteine proteases, a papain-like protease, …

  97. Volume-conserving trans–cis isomerization pathways in photoactive yellow protein visualized by picosecond X-ray crystallography

    0.0 out of 5 stars 

    01 Feb 2013 | BioXFEL Publications | Contributor(s): Yang Ouk Jung, Jae Hyuk Lee, Joonghan Kim, Marius Schmidt, Keith Moffat, Vukica Šrajer, Hyotcherl Ihee

    http://dx.doi.org/10.1038/nchem.1565 journal-article Jung, Y.O. et al., 2013. Volume-conserving trans–cis isomerization pathways in photoactive yellow protein visualized by picosecond X-ray crystallography. Nature Chemistry, 5(3), pp.212–220. Available at: …

  98. Watching proteins function with time-resolved x-ray crystallography

    0.0 out of 5 stars 

    03 Jul 2017 | BioXFEL Publications | Contributor(s): Vukica Šrajer, Marius Schmidt

    http://dx.doi.org/10.1088/1361-6463/aa7d32 journal-article Šrajer, V. & Schmidt, M., 2017. Watching proteins function with time-resolved x-ray crystallography. Journal of Physics D: Applied Physics, 50(37), p.373001. Available at: http://dx.doi.org/10.1088/1361-6463/aa7d32. Vukica Šrajer and …

  99. What is the outcome of your crystallization experiment

    0.0 out of 5 stars 

    14 Oct 2015 | Teaching Materials | Contributor(s): Joseph Luft

    Joe Luft discusses the detection of hits in crystallization screening experiments for both macro and nanocrystals.

  100. What it takes for a successful mix-and-inject serial crystallography experiment: from a sample preparation and sample delivery perspective

    0.0 out of 5 stars 

    21 Oct 2021 | BioXFEL Publications | Contributor(s): Kara Zielinski, Lois Pollack

    http://dx.doi.org/10.1107/s0108767321099219 journal-article Zielinski, K., & Pollack, L. (2021). What it takes for a successful mix-and-inject serial crystallography experiment: from a sample preparation and sample delivery perspective. Acta Crystallographica Section A Foundations and Advances, …