News

Dynamics and Kinetics in Structural Biology

Understand the latest experimental tools in structured biology with this pioneering work by Keith Moffat and Eaton E. Lattman. Structural biology seeks to understand the chemical mechanisms and functions of biological molecules based on their atomic structures. Until recently, these structures have been studied only statically.

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Visualizing the 3D Structures of Molecules Involved in Life's Processes UPR Workshop

"Visualizing the 3D Structures of Molecules Involved in Life's Processes" Workshop

Undergraduate students attending college in Puerto Rico are invited to participate in this two-day workshop.

 

The workshop will be available in the following locations from 8am - 4pm each day:

  • February 5th - 6th in Mayaguez
  • February 7th - 8th in San Juan

 

Workshop Components:

  1. Focused on structural biology at X-ray sources

  2. Lectures and practicals from experts in the field

  3. Real synchrotron data collection and data processing opportunities

     

General Workshop Topics:

  1. Introduction to Structural Biology

  2. Crystallographic approaches

  3. X-ray imaging at synchrotrons and XFELs)

  4. Complementary techniques

     

    CLICK HERE TO REGISTER!

2024 BioXFEL Spring Symposium

The 2024 BioXFEL Spring Symposium will be at Arizona State University from March 6 – 7, 2024. The symposium will consist of scientist and student presentations, a poster session, and networking/recruitment opportunities.

 

List of Conference Hotels

 

Tentative List of Presenters

 

 

For registration payment and information, please click here.

 

 

Heterogeneity in M. tuberculosis β-lactamase inhibition by Sulbactam

In a paper just published in Nature Communications, a team of BioXFEL researchers and collaborators used mix-and-inject serial crystallography (MISC) to analyze the reaction of the β-lactamase BlaC from tuberculosis bacteria with the suicide inhibitor sulbactam (SUB).

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Earliest molecular events of vision revealed

A large international team lead by Valerie Paneels and Gebhard Schertler revealed the molecular mechanism of light receptor activation in the eyes of vertebrae animals by time-resolved serial femtosecond crystallography (TR-SFX). The article appeared in Nature online on March 22 2023. BioXFEL researchers Schmidt and Stojković were invited to write a News and Views article summarizing the general findings focused on the light-activated bovine rhodopsin.

The News and Views article is available here: https://www.nature.com/articles/d41586-023-00504-4.

 

Figure

Caption: The structure of the eye-pigment rhodopsin in the resting state. The retinal is shown in green in the 11-cis configuration. The retinal is bound via a Schiff-base to a lysine sidechain. BioXFEL researchers Schmidt and Stojković wrote a News and Views article in Nature summarizing newest results on the activation of rhodopsin by light.

2023 BioXFEL Conference

 

Click here for Conference Agenda

 

Click here for Welcome Packet  

 

The National Science Foundation BioXFEL Science and Technology Center is pleased to announce that it will be hosting its 10th Annual International Conference May 16 - 18, 2023. The "From Time-Resolved Structure Factor Amplitudes to Structure and Dynamics" workshop with Drs. Marius Schmidt, Sabine Botha, and Sebastian Westenhoff will be held May 15, 2023.

 

The BioXFEL Annual International Conference brings together experts in a variety of fields (structural biology, physics, biochemistry, and more) to discuss the most recent advances in structural biology using X-ray Free Electron Lasers (XFELs). The conference features talks by leading scientists in the field, a poster session, as well as networking, and professional development opportunities.

 

REGISTER HERE 

 

Conference Co-chairs:

Edward Snell (Hauptman-Woodward Institute)

Juan Lopez Garriga (University of Puerto Rico at Mayagüez)

Alexandra Ros (Arizona State University) 

 

Presenters:

***PLEASE NOTE: This list is being added to daily, so please check back to see the updated list as more presenters are added.***

Roberto Alonso Mori (Stanford)

Roberto Alvarez (ASU)

Thomas Barends (Max Planck Institute for Medical Research)

Shibom Basu (European Molecular Biology Laboratory)

Sabine Botha (Arizona State University)

Florian Dworkowski (Paul Scherrer Institute)

Hao Hu (Arizona State University)

Rebecca Jernigan (Arizona State University) (University of Arizona)

Robert Kaindl (Arizona State University)

Jan Kern (Lawrence Berkeley National Laboratory)

Matthias Kling (SLAC/Stanford University)

Juan Lopez-Garriga (University of Puerto Rico at Mayagüez)

Darya Marchany-Rivera (SLAC National Accelerator Laboratory)

Henrike Müller-Werkmeister (University of Potsdam)

Tek Narsingh Malla (University of Wisconsin-Milwaukee)

Lois Pollack (Cornell University)

Matthew Rodrigues (Paul Scherrer Institute)

Alexandra Ros (Arizona State University)

Christina Schmidt (Cornell)

Marius Schmidt (University of Wisconsin-Milwaukee)

Chenghua Shao (RCSB Protein Data Bank)

Megan Shelby (Lawrence Livermore National Laboratory)

Michael Steinmetz (Paul Scherrer Institute)

Emina Stojkovic (Northeastern Illinois University)

Mike Thompson (University of California Merced)

Raphael de Wijn (European XFEL)

Lainey Williamson (Cardiff University)

Sebastian Westenhoff (University of Gothenburg)

Kara Zielinski (Cornell)

 

 

Keynote Speaker:

Tabbetha Dobbins - Dept. of Physics & Astronomy (Rowan University)

 

Posters:

Poster abstracts can be submitted using this format (download as a Microsoft Word file to edit) to Michael Logar at  This email address is being protected from spambots. You need JavaScript enabled to view it.  

by April 1st. Posters submitted by April 1st may be selected for a talk. We cannot guarantee that abstracts submitted after April 1st will be considered for a talk.

A scientific poster session will be held during the evening on Tuesday, May 16th. 

Poster sizing requirements are 40" x 32" or less.

For BioXFEL members, please download the following template to use for your poster.

 

Registration Fees:

For more information to register click HERE.  

 

To Be a Sponsor or Exhibitor: 

Please look over our Sponsorship Brochure and contact Michael Logar at  This email address is being protected from spambots. You need JavaScript enabled to view it.  or 716-898-8594 for more information.