Popular Articles
- Crystal structure of CO-bound cytochrome c oxidase determined by serial femtosecond X-ray crystallography at room temperature
- NSF awards $22.5 million to capture biology at the atomic level using X-ray lasers
- BioXFEL Research Support Call for Proposals
- Frankuchen Award : ACA 2019
- UWM researchers create first 3D movie of virus in action
Archived Articles
News
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- Monday, 29 January 2018
New research published today in Nature Methods by BioXFEL researcher Tom Grant opens up new avenues for studying the structures of particles floating in solution.
Typically, molecular structures are determined using a technique known as crystallography, where molecules are chemically induced to align next to each other in a large 3D lattice.
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- Thursday, 02 November 2017
BioXFEL was well represented at the LCLS/SSRL Users' Meeting with Henry Chapman giving a plenary talk on Serial Femtosecond Crystallography: Past, Present, and Future featuring snippets from data as recent as 24 hours before the talk. David Bushnell, moderated a session that included the LCLS young investigator award and Linda Horton, Director of the Department of Energy Basic Energy Sciences Materials Science and Engineering Division. A meeting of the joint LCLS and SSRL Users Executive Committee took place with Linda Horton, Petra Fromme, David Bushnell and Edward Snell present.
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- Tuesday, 31 October 2017
A team of BioXFEL ASU scientists led by Professor and STC Member Alexandra Ros in the School of Molecular Sciences and the Biodesign Center for Applied Structural Discovery, has been just the second user group to conduct experiments at the brand new European X-ray free electron laser facility (EuXFEL) in Hamburg, Germany. This 1.5-billion-dollar facility is the third, and by far the most powerful, X-ray laser in the world. After ten years of construction, it opened for first experiments just a month ago.
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- Thursday, 05 October 2017
On October 4th, 2017, Drs. Jacques Dubochet (formerly of University of Lausanne in Switzerland), Joachim Frank (Columbia University), and Richard Henderson (British Medical Research Council’s Laboratory of Molecular Biology in Cambridge, UK) were awarded the Nobel Prize in Chemistry for developing cryo-electron microscopy (Cryo-EM) for the high resolution structure determination of biomolecules in solution.
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- Tuesday, 12 September 2017
Scientists who make movies of molecules in motion have a new high-speed camera to shoot with. The €1.2-billion (US$1.4-billion) European X-ray Free Electron Laser (XFEL) will start running its first experiments in September near Hamburg, Germany. The European XFEL fires powerful X-rays in bursts of a few hundred femtoseconds: so short that, like strobe lights, they can capture snapshots of jittery molecules frozen in time, and with a wavelength small enough to provide pictures at atomic resolution.
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- Tuesday, 29 August 2017
Mix-and-inject serial crystallography (MISC) is a technique designed to image enzyme catalyzed reactions in which small protein crystals are mixed with a substrate just prior to being probed by an X-ray pulse. This approach offers several advantages over flow cell studies. It provides (i) room temperature structures at near atomic resolution, (ii) time resolution ranging from microseconds to seconds, and (iii) convenient reaction initiation.
More Articles...
- Conformational landscape of a virus by single-particle X-ray scattering
- UWM researchers create first 3D movie of virus in action
- A Bright Future for Serial Femtosecond Crystallography with XFELs
- Experimental strategies for imaging bioparticles with femtosecond hard X-ray pulses
- Single-shot determination of focused FEL wave fields using iterative phase retrieval
